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Introduction to genome biology
Introduction to genome biology

... • Genes comprise only about 2% of the human genome; the rest consists of non-coding regions, whose functions may include providing chromosomal structural integrity and regulating when, where, and in what quantity proteins are made (regulatory regions). • The terms exon and intron refer to coding (tr ...
 Honors Biology Unit 6 Ch. 10 “DNA, RNA & Protein synthesis”
 Honors Biology Unit 6 Ch. 10 “DNA, RNA & Protein synthesis”

...  I can describe what happens during transcription.  I can describe what happens during translation.  I can explain how transcription and translation work together to make a protein. b. I can identify how each type of RNA is involved in protein synthesis. c. I can describe the functions of protein ...
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U - West Windsor-Plainsboro Regional School District

... • 3.2 million DNA base pairs • 1.5% encode proteins < = > 98.5% not protein encoding ...
Crash Course in Biochemistry
Crash Course in Biochemistry

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Unfolded Protein Response (UPR)
Unfolded Protein Response (UPR)

... Looking for transcription factors which bind to BiP promoter Nucleotide sequence of the 2140 to 219 region of the human GRP78 promoter. ...
DNA
DNA

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Genomics

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Nucleosides, nucleotides, nucleic acids

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3D Ribbon-like Model

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Derived copy of Bis2A 14.1 Bacterial Gene
Derived copy of Bis2A 14.1 Bacterial Gene

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Chapter 13.1 and 13.2 RNA, Ribosomes, and Protein Synthesis

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... For each hormone, a specific receptor exists within the cell. It is important to note one fundamental difference, however, between the steroid hormones and the other signaling molecules. The receptors for growth factors and neurotransmitters lie on the outer surface of the cell and directly bind the ...
Unit 2 DNA Outline - Westgate Mennonite Collegiate
Unit 2 DNA Outline - Westgate Mennonite Collegiate

... An operon is a cluster of genes usually coding for proteins related to a particular metabolic pathway, along with the short DNA sequences that control their transcription. The parts of an operon include a repressor and a regulator gene as well as the structural genes. Gene Expression in Eukaryotes S ...
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Bioinformatics and Personal Health/Intro computer lab

... transcription factors, inactivating them. When GA is present the DELLA domain binds the protein GID1. This binding causes the DELLA protein to be tagged for degradation (using ubiquitination). With DELLA proteins degraded the transcription factors are able to bind promoters and turn on gene expressi ...
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Protein Synthesis - MsJacksonsBiologyWiki
Protein Synthesis - MsJacksonsBiologyWiki

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RNA and Protein Synthesis

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Gel Electrophoresis

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Transcriptional regulation

In molecular biology and genetics, transcriptional regulation is the means by which a cell regulates the conversion of DNA to RNA (transcription), thereby orchestrating gene activity. A single gene can be regulated in a range of ways, from altering the number of copies of RNA that are transcribed, to the temporal control of when the gene is transcribed. This control allows the cell or organism to respond to a variety of intra- and extracellular signals and thus mount a response. Some examples of this include producing the mRNA that encode enzymes to adapt to a change in a food source, producing the gene products involved in cell cycle specific activities, and producing the gene products responsible for cellular differentiation in higher eukaryotes.The regulation of transcription is a vital process in all living organisms. It is orchestrated by transcription factors and other proteins working in concert to finely tune the amount of RNA being produced through a variety of mechanisms. Prokaryotic organisms and eukaryotic organisms have very different strategies of accomplishing control over transcription, but some important features remain conserved between the two. Most importantly is the idea of combinatorial control, which is that any given gene is likely controlled by a specific combination of factors to control transcription. In a hypothetical example, the factors A and B might regulate a distinct set of genes from the combination of factors A and C. This combinatorial nature extends to complexes of far more than two proteins, and allows a very small subset (less than 10%) of the genome to control the transcriptional program of the entire cell.
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