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Semiquantitative RT-PCR analysis
Semiquantitative RT-PCR analysis

... 2. Cloning of pGL3 promoter vectors containing promoter region: The 1560-bp DNA fragment of the p15INK4b promoter region and 975-bp DNA fragment of p19INK4d promoter region containing a potential FOXO binding sequence were amplified by PCR with 293T genomic DNA as a template. The 293T genomic DNA wa ...
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... Repression can occur at multiple loci A repressor will act on all loci that have a copy of its target operator sequence ...
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Basics of Molecular Biology

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BioInformatics at FSU - whose job is it and why it needs

... genome. (The cells of sexually reproducing organisms such as ourselves are generally diploid: they contain two copies of the genome, one inherited from the mother, the other from the father.) Closely related organisms can vary widely in the quantity of DNA in their genomes, even though they contain ...
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... • Could also be used to examine known motif enrichment • Is motif enrichment correlated with ChIP-seq enrichment? • Is motif more enriched in peak summits than peak flanks? • Motif analysis could identify transcription factor partners of ChIP-seq factors ...
summing-up - Zanichelli online per la scuola
summing-up - Zanichelli online per la scuola

... translated into proteins. In this case several copies of the virus are formed that destroy the host cell (lytic cycle). In other cases, the genetic material is integrated into the genome of the bacterium and duplicates with it (lysogenic cycle). ...
BIO 245: Principles of Genetics Course description BIO 245
BIO 245: Principles of Genetics Course description BIO 245

... mathematics (MAT 142, MAT 143 or higher level) or equivalent. Offered in fall semesters on the St. Thomas campus only. Goals & Objectives - Goal #1: To learn and apply concepts of modern transmission and molecular genetics. o Objective 1A: To identify and describe the process and purposes of the cel ...
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Editing-Regulation&GO - Bioinformatics Research Group at SRI

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transcript - Genetic Alliance UK
transcript - Genetic Alliance UK

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Investigating regulation of aging by transcription factors DAF 16 and

... each other in terms of promoting longevity in C. elegans. This will be done in the experiment using the aforementioned methods, which involve using RNA interference methods to silence certain genes. Through this, we can gain insight into whether the two transcription factors regulate each other and ...
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B8. Nucleic Acids (HL)

... coded by a sequence of nitrogenous bases • Through a series of processes (transcription and translation), the nitrogenous bases will come to dictate a series of amino acids – These amino acids will form a polypeptide which will in turn form a protein : GENE TO PROTEIN • Proteins directly or indirect ...
Medical School Biochemistry
Medical School Biochemistry

... characterized by the presence of sequences that are repeated in tandem a variable number of times; i.e., they contain a variable number of tandem repeats (VNTRs). What is the chance that two siblings will be indistinguishable based on genetic testing for hypervariability at one particular VNTR locus ...
gen-305-presentation-13-2016
gen-305-presentation-13-2016

... Copyright ©The McGraw-Hill Companies, Inc. Permission required for reproduction or display ...
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RNA polymerase - Industrial ISD
RNA polymerase - Industrial ISD

... • RNA polymerase separates the DNA strands at the appropriate point and bonds the RNA nucleotides as they base-pair along the DNA template. • Like DNA polymerases, RNA polymerases can add nucleotides only to the 3’ end of the growing ...
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Transkriptom a proteom - Univerzita Karlova v Praze

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21 356 Molecular Biology Spring 2017
21 356 Molecular Biology Spring 2017

... This course covers topics focused on gene expression and its regulation in eukaryotic cells. Specific areas of focus include: Gene organization and chromosome structure, Mechanisms of replication, Mutations, Mechanisms of DNA damage and repair, Transcription and regulation of RNA synthesis, Posttran ...
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Transcriptional regulation

In molecular biology and genetics, transcriptional regulation is the means by which a cell regulates the conversion of DNA to RNA (transcription), thereby orchestrating gene activity. A single gene can be regulated in a range of ways, from altering the number of copies of RNA that are transcribed, to the temporal control of when the gene is transcribed. This control allows the cell or organism to respond to a variety of intra- and extracellular signals and thus mount a response. Some examples of this include producing the mRNA that encode enzymes to adapt to a change in a food source, producing the gene products involved in cell cycle specific activities, and producing the gene products responsible for cellular differentiation in higher eukaryotes.The regulation of transcription is a vital process in all living organisms. It is orchestrated by transcription factors and other proteins working in concert to finely tune the amount of RNA being produced through a variety of mechanisms. Prokaryotic organisms and eukaryotic organisms have very different strategies of accomplishing control over transcription, but some important features remain conserved between the two. Most importantly is the idea of combinatorial control, which is that any given gene is likely controlled by a specific combination of factors to control transcription. In a hypothetical example, the factors A and B might regulate a distinct set of genes from the combination of factors A and C. This combinatorial nature extends to complexes of far more than two proteins, and allows a very small subset (less than 10%) of the genome to control the transcriptional program of the entire cell.
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