Spring 2015 CH 421 Name ________________________________________ Section ___________ Post‐lab 3: The Grignard Reaction: Preparation of an Alcohol
... 4) Aldehydes undergo reaction with a Grignard reagent to provide an alcohol product. Many aldehydes are prone to air oxidation. For instance, a bottle of benzaldehyde will turn from a clear liquid to a white solid if left open over time. What is the oxidation produ ...
... 4) Aldehydes undergo reaction with a Grignard reagent to provide an alcohol product. Many aldehydes are prone to air oxidation. For instance, a bottle of benzaldehyde will turn from a clear liquid to a white solid if left open over time. What is the oxidation produ ...
Kwang-Ting Liu Department of Chemistry National Taiwan
... American textbook is chosen for individual section according to the lecturer’s preference. • “Organic Chemistry B” is a two-semester course consists of three hours of lecture and one hour of recitation per week. ...
... American textbook is chosen for individual section according to the lecturer’s preference. • “Organic Chemistry B” is a two-semester course consists of three hours of lecture and one hour of recitation per week. ...
Chapter 7
... • We also saw that the alkynide ion can react with a methyl halide or a primary alkyl halide with no branching at the beta carbon • We should now recognize this as an Sn2 reaction with the alkynide ion as the nucleophile and the alkyl halide as the substrate ...
... • We also saw that the alkynide ion can react with a methyl halide or a primary alkyl halide with no branching at the beta carbon • We should now recognize this as an Sn2 reaction with the alkynide ion as the nucleophile and the alkyl halide as the substrate ...
Abstract OXIDATIVE TRANSFORMATIONS AND CYCLIZATIONS
... active esters with amines. An alternative approach, which is quite attractive from the economical and green chemistry point of view, is the oxidative amidation of aldehydes. Few reports adopting the above strategy have appeared in the literature which employs a transition metal catalyst in combinati ...
... active esters with amines. An alternative approach, which is quite attractive from the economical and green chemistry point of view, is the oxidative amidation of aldehydes. Few reports adopting the above strategy have appeared in the literature which employs a transition metal catalyst in combinati ...
Air-Stable Trialkylphosphonium Salts
... Isolated yields; average of two runs. b Literature yields, using P(t-Bu)3 (ref 3c), are reported in parentheses. c The E olefin is produced with >20:1 E:Z selectivity. ...
... Isolated yields; average of two runs. b Literature yields, using P(t-Bu)3 (ref 3c), are reported in parentheses. c The E olefin is produced with >20:1 E:Z selectivity. ...
Reactions of 2, 6-cycloheptadienone and 2, 7
... to 1 1. with ethanol. Reference standards were prepared from a titrated solution of 70% HCIOl in EtOH, EtOH, hexane, and the standard solution such that the final solutions contained 5.0 ml of standard, 1.0 ml of EtOH, and 2.0 ml of hexane. The amount of perchlorate formed in a reaction was determin ...
... to 1 1. with ethanol. Reference standards were prepared from a titrated solution of 70% HCIOl in EtOH, EtOH, hexane, and the standard solution such that the final solutions contained 5.0 ml of standard, 1.0 ml of EtOH, and 2.0 ml of hexane. The amount of perchlorate formed in a reaction was determin ...
The Formation of 2,2,4-Trimethyl-2,3-dihydro-1H-1,5
... Reactions of o-phenylenediamine with a dicarboxylic acid can produce several different products depending on the specific conditions [1]. In the presence of cyclization agents such as hydrochloric acid or polyphosphoric acid, these reactions have been reported to give benzimidazoles [2,3]. This is a ...
... Reactions of o-phenylenediamine with a dicarboxylic acid can produce several different products depending on the specific conditions [1]. In the presence of cyclization agents such as hydrochloric acid or polyphosphoric acid, these reactions have been reported to give benzimidazoles [2,3]. This is a ...
chm 434f/1206f solid state materials chemistry
... • Form or morphology and physical size of product controls synthesis method of choice and potential utility • Single crystal, phase pure, defect free solids - do not exist and if they did not likely of much interest! • Single crystal (SC) that has been defect modified with dopants - intrinsic vs ext ...
... • Form or morphology and physical size of product controls synthesis method of choice and potential utility • Single crystal, phase pure, defect free solids - do not exist and if they did not likely of much interest! • Single crystal (SC) that has been defect modified with dopants - intrinsic vs ext ...
Carbohydrate Chemistry
... Include appropriate background information. If a key starting compound in a synthesis is cited without further details as to its origins, you may need to look up the paper that describes its preparation. Other background information should be included to the extent that you feel it is necessary to u ...
... Include appropriate background information. If a key starting compound in a synthesis is cited without further details as to its origins, you may need to look up the paper that describes its preparation. Other background information should be included to the extent that you feel it is necessary to u ...
PDF document
... ILs have found wide applications in chemical synthesis,10–12 biocatalytic transformations,13 electrochemistry,14 and analytical and separation science.15 In view of both the advantages and disadvantages of homogeneous and heterogeneous catalysts, and to improve catalyst recovery, multiphase systems, ...
... ILs have found wide applications in chemical synthesis,10–12 biocatalytic transformations,13 electrochemistry,14 and analytical and separation science.15 In view of both the advantages and disadvantages of homogeneous and heterogeneous catalysts, and to improve catalyst recovery, multiphase systems, ...
Direct ester condensation catalyzed by bulky diarylammonium
... condensation reaction of carboxylic acids with alcohols is catalyzed by Brønsted acids such as HCl, H2SO4, p-toluenesulfonic acid and so on for acid-resistance substrates. For acid-sensitive substrates, weak Brønsted acids such as pyridinium p-toluenesulfonate should be used. However, these have low ...
... condensation reaction of carboxylic acids with alcohols is catalyzed by Brønsted acids such as HCl, H2SO4, p-toluenesulfonic acid and so on for acid-resistance substrates. For acid-sensitive substrates, weak Brønsted acids such as pyridinium p-toluenesulfonate should be used. However, these have low ...
16.2: Structure and Bonding in Ethers and Epoxides
... 16.1: Nomenclature of Ethers, Epoxides, and Sulfides (Please read) 16.2: Structure and Bonding in Ethers and Epoxides The ether oxygen is sp3-hybridized and tetrahedral. In general, the C-O bonds of ethers have low reactivity. 16.3: Physical Properties of Ethers The O-H group of alcohols act as both ...
... 16.1: Nomenclature of Ethers, Epoxides, and Sulfides (Please read) 16.2: Structure and Bonding in Ethers and Epoxides The ether oxygen is sp3-hybridized and tetrahedral. In general, the C-O bonds of ethers have low reactivity. 16.3: Physical Properties of Ethers The O-H group of alcohols act as both ...
Screening - Entrance
... 11. An aqueous solution of 6.3 g oxalic acid dehydrate is made up to 250ml> the volume of 0.1N NaOH required to completely neutralize 10ml of this solution is : (a) 40ml (b) 20ml (c) 10ml (d) 4ml 12. The correct order of basicities of the following compounds is : ...
... 11. An aqueous solution of 6.3 g oxalic acid dehydrate is made up to 250ml> the volume of 0.1N NaOH required to completely neutralize 10ml of this solution is : (a) 40ml (b) 20ml (c) 10ml (d) 4ml 12. The correct order of basicities of the following compounds is : ...
Chapter 7
... • We also saw that the alkynide ion can react with a methyl halide or a primary alkyl halide with no branching at the beta carbon • We should now recognize this as an Sn2 reaction with the alkynide ion as the nucleophile and the alkyl halide as the substrate ...
... • We also saw that the alkynide ion can react with a methyl halide or a primary alkyl halide with no branching at the beta carbon • We should now recognize this as an Sn2 reaction with the alkynide ion as the nucleophile and the alkyl halide as the substrate ...
3 金属材料合成3-2 B
... zGeneral idea is the same as the growth of gold nanorods (seed-mediated method)Slightly change the conditions when growing nanorods (concentration of different reactants)Cubes, hexagon, triangle, tetrapods, branchedExperimental methods involve: 1) the preparation of Au seed particles; and 2) the sub ...
... zGeneral idea is the same as the growth of gold nanorods (seed-mediated method)Slightly change the conditions when growing nanorods (concentration of different reactants)Cubes, hexagon, triangle, tetrapods, branchedExperimental methods involve: 1) the preparation of Au seed particles; and 2) the sub ...
Lecture 28 - The Cook Group @ NDSU
... Free radical halogenation of alkanes will produce alkyl halides, however, the reaction usually produces a mixture of products. Note that the reaction proceeds via carbon radical intermediates and similar to carbocations, a carbon radical is more stable if it is more substituted. Thus, tertiary hydro ...
... Free radical halogenation of alkanes will produce alkyl halides, however, the reaction usually produces a mixture of products. Note that the reaction proceeds via carbon radical intermediates and similar to carbocations, a carbon radical is more stable if it is more substituted. Thus, tertiary hydro ...
Amines - ChemConnections
... reaction of p-nitroaniline with NaNO2 in H2SO4 followed by the addition of ...
... reaction of p-nitroaniline with NaNO2 in H2SO4 followed by the addition of ...
Chapter 13. Plannig and Execution of Multistep Synthesis
... vinyl ether in dihydropyran. (catalyst: p-toluenesulfonic acid or its pyridinium salt) ...
... vinyl ether in dihydropyran. (catalyst: p-toluenesulfonic acid or its pyridinium salt) ...
Discodermolide
(+)-Discodermolide is a polyketide natural product found to stabilize microtubule. (+)-discodermolide was isolated by Gunasekera and his co-workers at the Harbor Branch Oceanographic Institute from the deep-sea sponge Discodermia dissoluta in 1990. (+)-Discodermolide was found to be a potent inhibitor of tumor cell growth in several MDR cancer cell lines. (+)-discodermolide also shows some unique characters, including a linear backbone structure, immunosuppressive properties both in vitro and in vivo, potent induction of an accelerated senescence phenotype, and synergistic antiproliferative activity in combination with paclitaxel. Discodermolide was recognized as one of the most potent natural promoters of tubulin assembly. A large number of efforts toward the total synthesis of (+)-discodermolide were directed by its interesting biological activities and extreme scarcity of natural sources (0.002% w/w from frozen marine sponge). The compound supply necessary for complete clinical trials cannot be met by harvesting, isolation, and purification. As of 2005, attempts at synthesis or semi-synthesis by fermentation have proven unsuccessful. As a result, all discodermolide used in preclinical studies and clinical trials has come from large-scale total synthesis.