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Nicotine injections into the ventral tegmental area increase
Nicotine injections into the ventral tegmental area increase

... stimulatory effect of locally applied nicotine was completely blocked by pretreatment with mecamylamine (1.0 mg/kg, s.c.). Repeated intra-tegmental iniections of a subthreshold dose of nicotine (2.0 btg/side every 2 days), gradually increased locomotion, compared to the effect of acute intra-tegment ...
Implications of Polychronous Neuronal Groups for the Nature of Mental Representations
Implications of Polychronous Neuronal Groups for the Nature of Mental Representations

... it is important to understand how they are generated and propagated. An individual neuron remains at its resting potential until it receives, or “observes”, a sufficient number of spikes in a short enough period of time, at which point this coincident input causes the neuron to generate an action po ...
Behavioural Brain Research Ventral pallidum roles in reward and
Behavioural Brain Research Ventral pallidum roles in reward and

... eating and food ‘wanting’ [62]. The ventral pallidum may play an even more unique role in mediating reward beyond being necessary for motivated eating: it is the only structure known to us in which local lesions also eliminate normal ‘liking’ for sucrose, and replace it with ‘disliking’ [60]. ‘Likin ...
Chapter 122: Neurocircuitry Of Parkinson`s Disease
Chapter 122: Neurocircuitry Of Parkinson`s Disease

... SNr can be broadly subdivided into a dorsolateral sensorimotor and a ventromedial associative territory (78). By and large, projections from these areas target the same nuclei that also receive GPi output, but tend to terminate in different regions of these nuclei. Projections from the medial SNr to ...
Diverse functions of perineuronal nets
Diverse functions of perineuronal nets

... however, that PN-like structures are able to appear without the presence of glial cells (Miyata et al. 2005) and dissociated hippocampal neurons in culture can form net-like ECM (John et al. 2006, Dityatev et al. 2007, Frischknecht et al. 2009). Formation of PNs depends on neuronal activity. Blockin ...
Heterogeneous Integration of Bilateral Whisker Signals by Neurons
Heterogeneous Integration of Bilateral Whisker Signals by Neurons

Maruska & Tricas 2011
Maruska & Tricas 2011

... conspecific sounds triggers luteinizing hormone release in some birds (Cheng et al., 1998; Maney et al., 2007). While these studies are consistent with the hypothesis that perception of context-specific auditory cues can influence the GnRH1 system and reproductive physiology, it remains unclear whether ...
Neuroanatomical correlates of the near response: voluntary
Neuroanatomical correlates of the near response: voluntary

... down, cognitive-perceptual processing occurs within the accommodative system. ...
optimal feedback control and the neural basis of volitional motor
optimal feedback control and the neural basis of volitional motor

... Point-to-point reaching movements are quite simple with regards to the motion of the hand in space. Hand motion is relatively straight for reaching movements in different spatial directions (panel a). Hand movements with similar magnitudes but in different directions produce large variations (anisot ...
download file
download file

... of rat posterior auditory field (PAF) neurons, we compared neurophysiological responses to simple tones, frequency modulated (FM) sweeps, and amplitude modulated noise and tones with responses of primary auditory cortex (A1) neurons. PAF neurons have excitatory receptive fields that are on average 6 ...
The dorsal raphe nucleus—From silver stainings to a role in
The dorsal raphe nucleus—From silver stainings to a role in

... In their studies on the rat DRN, Dahlström and Fuxe used formaldehyde-induced fluorescence (FIF), which had been developed by Falck et al. (1962) for visualization of monoamines. The FIF-technique soon became the most popular tool for visualizing serotonergic neurons in the DRN and elsewhere. A majo ...
Thalamic POm projections to the dorsolateral striatum of rats
Thalamic POm projections to the dorsolateral striatum of rats

... regulating the selection and execution of specific motor behaviors (McHaffie et al. 2005; Redgrave et al. 2010; Smith et al. 2011). Furthermore, although the dorsomedial striatum is important for mediating goal-directed behaviors, the dorsolateral striatum (DLS) is necessary for executing well-learn ...
Neuronal Correlates for Preparatory Set Associated with Pro
Neuronal Correlates for Preparatory Set Associated with Pro

... Electrophysiolog y. All experimental procedures were in accordance with the C anadian Council on Animal C are policy on the use and care of laboratory animals and approved by the Queen’s University Animal C are Committee. Surgical, electrophysiological, and data acquisition methods were described pr ...
ConcTheory
ConcTheory

... Electronic systems have been designed and built which can perform extremely complex combinations of functions using large numbers of components. Such systems employ thousands of millions of transistors to perform combinations of thousands of interacting features. The design process for such systems ...
Clinical Investigative Study Detectability of Neural Tracts and Nuclei
Clinical Investigative Study Detectability of Neural Tracts and Nuclei

... of the lower pons. The corticospinal tract (1) is depicted as a large dark blue region between two red compartments (ie, the superficial layer and the deep layer of the transverse pontine fibers in the middle of the ventral part of the pons). The medial lemniscus (2) is observed as a blue transverse s ...
PDF - Kalina Christoff
PDF - Kalina Christoff

Hindbrain noradrenergic A2 neurons: diverse roles in autonomic
Hindbrain noradrenergic A2 neurons: diverse roles in autonomic

... emotional and cognitive events can modulate visceral motor outflow and also a route through which interoceptive feedback from the body can impact hypothalamic functions as well as emotional and cognitive processing. This review considers some of the hallmark anatomical and chemical features of A2 ne ...
189084_189084 - espace@Curtin
189084_189084 - espace@Curtin

... The three main dopamine cell groups of the brain are located in the substantia nigra (A9), ventral tegmental area (A10), and retrorubral field (A8). Several subdivisions of these cell groups have been identified in rats and humans but have not been well described in mice, despite the increasing use ...
Specificity and Plasticity of Thalamocortical Connections in Sema6A
Specificity and Plasticity of Thalamocortical Connections in Sema6A

... Semaphorin-6A to test this model. In these mutants, Semaphorin6A axons from the visual part of the thalamus are subcortically misrouted and fail to innervate the presumptive visual cortex, which is instead invaded by somatosensory thalamic axons. Despite this major disruption in initial connectivity ...
Chapter 36 Locomotion
Chapter 36 Locomotion

... For almost half a century following these early studies few investigations were aimed at establishing the neural mechanisms for walking. Instead, research on motor systems focused on the organization of spinal reflex pathways and the mechanisms of synaptic integration within the spinal cord (see Cha ...
View/Open
View/Open

... control signals from two major sources: (1) corticofugal fibers returning in a backward direction from the primary visual cortex to the lateral geniculate nucleus, and (2) reticular areas of the mesencephalon. Both of these are inhibitory and, when stimulated, can turn off transmission through selec ...
Spike-Timing Theory of Working Memory
Spike-Timing Theory of Working Memory

... exploit a well-known feature of the brain — its ability to use precisely timed spiking events in its operation — to show how working memory functionality can emerge in the brain’s vast memory repertoire. Our neural simulations explain many features of neural activity observed in vivo during working ...
the primate amygdala and reinforcement: a
the primate amygdala and reinforcement: a

... testing is performed in a Wisconsin General Test Apparatus, amygdala lesions may not produce significant deficits partly because the neutral visual stimulus is being associated with a visual stimulus with secondary reinforcing properties, the sight of food; and partly because with spaced trials, a h ...
Glutamate Receptors
Glutamate Receptors

Methods of Studying The Nervous System - U
Methods of Studying The Nervous System - U

... horizontal sections where radio-activity has accumulated, and thus it indicates what areas were particularly active during the test Pinel's Biopsychology, 5th Ed. ...
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Neuroeconomics

Neuroeconomics is an interdisciplinary field that seeks to explain human decision making, the ability to process multiple alternatives and to follow a course of action. It studies how economic behavior can shape our understanding of the brain, and how neuroscientific discoveries can constrain and guide models of economics.It combines research methods from neuroscience, experimental and behavioral economics, and cognitive and social psychology. As research into decision-making behavior becomes increasingly computational, it has also incorporated new approaches from theoretical biology, computer science, and mathematics. Neuroeconomics studies decision making, by using a combination of tools from these fields so as to avoid the shortcomings that arise from a single-perspective approach. In mainstream economics, expected utility (EU), and the concept of rational agents, are still being used. Many economic behaviors are not fully explained by these models, such as heuristics and framing.Behavioral economics emerged to account for these anomalies by integrating social, cognitive, and emotional factors in understanding economic decisions. Neuroeconomics adds another layer by using neuroscientific methods in understanding the interplay between economic behavior and neural mechanisms. By using tools from various fields, some scholars claim that neuroeconomics offers a more integrative way of understanding decision making.
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