electrophysiological and synaptic properties of rat superior and
... of involved responses (i.e., in terms of short term and long-term mechanisms that control blood pressure) (Boron and Boulpaep, 2009). Short term regulation of blood pressure occurs within seconds to minutes, and is mediated predominantly by the baroreceptor and Starling reflexes. While these shortte ...
... of involved responses (i.e., in terms of short term and long-term mechanisms that control blood pressure) (Boron and Boulpaep, 2009). Short term regulation of blood pressure occurs within seconds to minutes, and is mediated predominantly by the baroreceptor and Starling reflexes. While these shortte ...
The Classical Complement Cascade Mediates
... RGCs that were acutely isolated (Figure 1B) as well as in situ hybridization on whole retina (Figure 1C). We found that C1q mRNA levels were highest in postnatal RGCs between P5 and P10 and declined significantly by P30 (Figures 1B and 1C). Thus, C1q mRNA is expressed by RGCs in vitro in response to ...
... RGCs that were acutely isolated (Figure 1B) as well as in situ hybridization on whole retina (Figure 1C). We found that C1q mRNA levels were highest in postnatal RGCs between P5 and P10 and declined significantly by P30 (Figures 1B and 1C). Thus, C1q mRNA is expressed by RGCs in vitro in response to ...
Histamine in the Nervous System
... tuberomamillary nucleus of the posterior hypothalamus and send their axons all over the central nervous system. Active solely during waking, they maintain wakefulness and attention. Three of the four known histamine receptors and binding to glutamate NMDA receptors serve multiple functions in the br ...
... tuberomamillary nucleus of the posterior hypothalamus and send their axons all over the central nervous system. Active solely during waking, they maintain wakefulness and attention. Three of the four known histamine receptors and binding to glutamate NMDA receptors serve multiple functions in the br ...
For Peer Review - diss.fu
... modulation of ascending monoamine systems in response to afferents from limbic regions and basal ganglia. The LHb is implicated in various biological functions, such as reward, sleepwake cycle, feeding, pain processing and memory formation. The modulatory role of the LHb is partly assumed by putativ ...
... modulation of ascending monoamine systems in response to afferents from limbic regions and basal ganglia. The LHb is implicated in various biological functions, such as reward, sleepwake cycle, feeding, pain processing and memory formation. The modulatory role of the LHb is partly assumed by putativ ...
Fig. 1
... studied Hsp90 subcellular distribution in cultured hippocampal neurons in different developmental stages, including neurites' growth, axon elongation and dendrites' development and maturation. Hippocampal neurons were fixed at different developmental stages (1, 2, 3, 6, 21 days in vitro, DIV) and sta ...
... studied Hsp90 subcellular distribution in cultured hippocampal neurons in different developmental stages, including neurites' growth, axon elongation and dendrites' development and maturation. Hippocampal neurons were fixed at different developmental stages (1, 2, 3, 6, 21 days in vitro, DIV) and sta ...
Expression of pituitary adenylate cyclase activating
... sensory SP- and CGRP-containing nerves in the cervix and was designed to determine if the neuropeptide pituitary adenylate cyclase-activating polypeptide (PACAP) could also play a role in cervical function, such as cervical ripening. PACAP has been identifi in nerves in the female genital tract [7,8 ...
... sensory SP- and CGRP-containing nerves in the cervix and was designed to determine if the neuropeptide pituitary adenylate cyclase-activating polypeptide (PACAP) could also play a role in cervical function, such as cervical ripening. PACAP has been identifi in nerves in the female genital tract [7,8 ...
projecting to oculomotor regions of the pons Activity of monkey
... of the frontal eye field caused omnipause neurons to stop firing. The cessation in firing appeared to be immediate, within ~5 ms. The time that the omnipause neuron remained quiet depended on the intensity of the cortical stimulus and lasted up to 30 ms after a train of three stimulus pulses lasting ...
... of the frontal eye field caused omnipause neurons to stop firing. The cessation in firing appeared to be immediate, within ~5 ms. The time that the omnipause neuron remained quiet depended on the intensity of the cortical stimulus and lasted up to 30 ms after a train of three stimulus pulses lasting ...
Selectivity for the Shape, Size, and Orientation of Objects for
... orientation of objects for grasping in neurons of monkey parietal area AIP. J. Neurophysiol. 83: 2580 –2601, 2000. In this study, we mainly investigated the visual selectivity of hand-manipulation-related neurons in the anterior intraparietal area (area AIP) while the animal was grasping or fixating ...
... orientation of objects for grasping in neurons of monkey parietal area AIP. J. Neurophysiol. 83: 2580 –2601, 2000. In this study, we mainly investigated the visual selectivity of hand-manipulation-related neurons in the anterior intraparietal area (area AIP) while the animal was grasping or fixating ...
Saccade Target Selection in the Superior - Smith
... task, while movement-related activity in the two tasks was comparable. Further experiments showed that much of the reduction in the initial visual response during search was due to lateral inhibition, although a top-down task-related component was also evident. Although the initial visual activity d ...
... task, while movement-related activity in the two tasks was comparable. Further experiments showed that much of the reduction in the initial visual response during search was due to lateral inhibition, although a top-down task-related component was also evident. Although the initial visual activity d ...
Involvement of GABAergic and cholinergic medial septal neurons in
... Hippocampal theta rhythm (HPC) may be important for various phenomena, including attention and acquisition of sensory information. Two types of HPC (types I and II) exist based on pharmacological, behavioral, and electrophysiological characteristics. Both types occur during locomotion, whereas onl ...
... Hippocampal theta rhythm (HPC) may be important for various phenomena, including attention and acquisition of sensory information. Two types of HPC (types I and II) exist based on pharmacological, behavioral, and electrophysiological characteristics. Both types occur during locomotion, whereas onl ...
Selectivity for the Shape, Size, and Orientation of Objects for
... Kaseda, and Hideo Sakata. Selectivity for the shape, size, and orientation of objects for grasping in neurons of monkey parietal area AIP. J. Neurophysiol. 83: 2580 –2601, 2000. In this study, we mainly investigated the visual selectivity of hand-manipulation-related neurons in the anterior intrapar ...
... Kaseda, and Hideo Sakata. Selectivity for the shape, size, and orientation of objects for grasping in neurons of monkey parietal area AIP. J. Neurophysiol. 83: 2580 –2601, 2000. In this study, we mainly investigated the visual selectivity of hand-manipulation-related neurons in the anterior intrapar ...
Serotonin in the inferior colliculus fluctuates with behavioral state
... sensory systems, including the auditory system. Most nuclei in the auditory brainstem and midbrain receive robust 5-HTergic projections (Hurley and Thompson, 2001; Klepper and Herbert, 1991; Woods and Azeredo, 1999). The effects of 5-HT on auditory response properties in these regions have been char ...
... sensory systems, including the auditory system. Most nuclei in the auditory brainstem and midbrain receive robust 5-HTergic projections (Hurley and Thompson, 2001; Klepper and Herbert, 1991; Woods and Azeredo, 1999). The effects of 5-HT on auditory response properties in these regions have been char ...
DOES ISCHEMIA CAUSE ACUTE NEURONAL DAMAGE BY CONVERTING THE NA /K
... scrutiny by neuroscientists. We hypothesized that this toxin could provide insight as to how ischemia acutely damages neurons at the molecular level. Palytoxin (PTX) specifically binds the Na+/K+ ATPase molecule at nanomolar concentrations, converting it from an ATP-requiring transporter to an open ...
... scrutiny by neuroscientists. We hypothesized that this toxin could provide insight as to how ischemia acutely damages neurons at the molecular level. Palytoxin (PTX) specifically binds the Na+/K+ ATPase molecule at nanomolar concentrations, converting it from an ATP-requiring transporter to an open ...
Isoform-specific expression and function of neuregulin
... (Meyer and Birchmeier, 1995). Mutations in neuregulin also impair development of the myocardium, which is the likely cause of death of mutant embryos on day 10.5 of development (Meyer and Birchmeier, 1995; Kramer et al., 1996). In the myocardium, similar defects are observed in animals that lack erb ...
... (Meyer and Birchmeier, 1995). Mutations in neuregulin also impair development of the myocardium, which is the likely cause of death of mutant embryos on day 10.5 of development (Meyer and Birchmeier, 1995; Kramer et al., 1996). In the myocardium, similar defects are observed in animals that lack erb ...
Multimodal Integration in Rostral Fastigial Nucleus Provides an
... signals underlies the accurate computation of body motion. Furthermore, the same neurons that encode body motion (i.e., bimodal neurons) most likely encode vestibular signals in a body-referenced coordinate frame, since the integration of proprioceptive and vestibular information is required for bot ...
... signals underlies the accurate computation of body motion. Furthermore, the same neurons that encode body motion (i.e., bimodal neurons) most likely encode vestibular signals in a body-referenced coordinate frame, since the integration of proprioceptive and vestibular information is required for bot ...
carboxylesterase 1 plays an essential role in non
... often present in patients with metabolic diseases. Hyperinsulinemia and hyperglycemia induce sterol regulatory element-binding protein 1c (SREBP-1c) and carbohydrate response element binding protein (ChREBP) in the liver, subsequently activate lipogenic genes and increase hepatic de novo lipogenesis ...
... often present in patients with metabolic diseases. Hyperinsulinemia and hyperglycemia induce sterol regulatory element-binding protein 1c (SREBP-1c) and carbohydrate response element binding protein (ChREBP) in the liver, subsequently activate lipogenic genes and increase hepatic de novo lipogenesis ...
basic mechanisms of sleep
... REM induction sites, carbachol injection into a more lateral pontine site in the caudal peribrachial area has been shown to induce long-term (more than 7 days) REM enhancement (19) and long-term PGO enhancement but without REM enhancement (20). In vivo cholinergic REM enhancement and a specific carb ...
... REM induction sites, carbachol injection into a more lateral pontine site in the caudal peribrachial area has been shown to induce long-term (more than 7 days) REM enhancement (19) and long-term PGO enhancement but without REM enhancement (20). In vivo cholinergic REM enhancement and a specific carb ...
University of Groningen Gustatory neural processing in the
... processes extending into an apical taste pore 89. Mature taste receptor cells have a life span of 10 - 14 days and are continually replenished from precursor cells, found at the base of the taste bud. Taste stimuli are dissolved during mastication and reach the apical microvilli of taste cells by mi ...
... processes extending into an apical taste pore 89. Mature taste receptor cells have a life span of 10 - 14 days and are continually replenished from precursor cells, found at the base of the taste bud. Taste stimuli are dissolved during mastication and reach the apical microvilli of taste cells by mi ...
Hikosaka O - lsr
... Recently, however, the habenula has attracted a great deal of attention. One main reason for this is probably the part that it plays in the regulation of dopamine and serotonin systems. Experimental and clinical studies have shown that these neuromodulators are essential for normal motor and mental ...
... Recently, however, the habenula has attracted a great deal of attention. One main reason for this is probably the part that it plays in the regulation of dopamine and serotonin systems. Experimental and clinical studies have shown that these neuromodulators are essential for normal motor and mental ...
Kazumi TAKAHASHI†*, Jian-Sheng LIN† and Kazuya - HAL
... The preoptic area (POA) of the anterior hypothalamus and the adjacent basal forebrain (BFB) play an important role in the regulation of homeostatic and cognitive processes, including blood pressure, thermoregulation, sexual behavior, attention, learning, and cortical activity (Boulant and Dean, 1986 ...
... The preoptic area (POA) of the anterior hypothalamus and the adjacent basal forebrain (BFB) play an important role in the regulation of homeostatic and cognitive processes, including blood pressure, thermoregulation, sexual behavior, attention, learning, and cortical activity (Boulant and Dean, 1986 ...
Development, validation and biological application of
... discussing science. I still do not understand why, being such an intelligent person, he still supports the Oklahoma Sooners, but to each his own I suppose. I don’t think I have ever met anyone as enthusiastic as Dr. John Jones when it comes to tackling down novel methods and ideas. He is always read ...
... discussing science. I still do not understand why, being such an intelligent person, he still supports the Oklahoma Sooners, but to each his own I suppose. I don’t think I have ever met anyone as enthusiastic as Dr. John Jones when it comes to tackling down novel methods and ideas. He is always read ...
α-Synuclein and dopamine at the crossroads of Parkinson`s disease
... control, or mRNA stability regulated by the 3′-untranslated region (UTR) (see below), is the real functional genetic mechanism underlying disease susceptibility. Although duplication and triplication of the SNCA locus elevate α-synuclein expression and cause familial PD [11,14], the broader question ...
... control, or mRNA stability regulated by the 3′-untranslated region (UTR) (see below), is the real functional genetic mechanism underlying disease susceptibility. Although duplication and triplication of the SNCA locus elevate α-synuclein expression and cause familial PD [11,14], the broader question ...
Article - Leslie Vosshall - The Rockefeller University
... with and is modulated by foraging experience outside the confines of the hive (Winnington et al., 1996). Previous studies in Drosophila showed that exposing flies to a single odor for several days causes stimulus-dependent decreases in glomerulus volume (Devaud et al., 2001, 2003). These earlier exp ...
... with and is modulated by foraging experience outside the confines of the hive (Winnington et al., 1996). Previous studies in Drosophila showed that exposing flies to a single odor for several days causes stimulus-dependent decreases in glomerulus volume (Devaud et al., 2001, 2003). These earlier exp ...
Dynamics of sensory processing in the dual olfactory pathway of the
... mixtures at the AL output (Galizia and Kimmerle 2004; Krofczik et al. 2008; Yamagata et al. 2009). 3.2. Characteristic differences of lateral and median uniglomerular projection neurons Based on intracellular recording and staining of uniglomerular projection neurons, Müller et al. (2002) reported t ...
... mixtures at the AL output (Galizia and Kimmerle 2004; Krofczik et al. 2008; Yamagata et al. 2009). 3.2. Characteristic differences of lateral and median uniglomerular projection neurons Based on intracellular recording and staining of uniglomerular projection neurons, Müller et al. (2002) reported t ...
The basal forebrain cholinergic projection system in mice. In
... Usually neurons projecting to the hippocampus that are located rostrally in the basal forebrain are not included in the term nucleus basalis, although amygdalopetal neurons that are intermingled with corticopetal cells may be included. Whereas ACh serves as a direct neurotransmitter at the neuromusc ...
... Usually neurons projecting to the hippocampus that are located rostrally in the basal forebrain are not included in the term nucleus basalis, although amygdalopetal neurons that are intermingled with corticopetal cells may be included. Whereas ACh serves as a direct neurotransmitter at the neuromusc ...