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touch and pain - Stark home page
touch and pain - Stark home page

... Lower limbs medial in gracile tract. Upper limbs lateral in cuneate tract. ipsilateral projection First nucleus is in lower medulla There is a cross-over, and then the next nucleus is in the thalamus. •  This lemnicsal system is evolutionarily "new" (reptiles and above) and is for localized touch. ...
Chapter 3
Chapter 3

... • dopamine: responsible for emotions, addictive behaviors – Regulates skeletal muscle tone – Parkinson’s disease result of degeneration of dopamine-secreting neurons • serotonin responsible for mood control, appetite, sleep induction – SSRIs prevent reuptake – Zoloft, Prozac for treatment of depress ...
LO #1
LO #1

... Action potentials are the basic unit of signaling in the central nervous system (CNS). Neurons are complex organs (computers?) that receive signals from many other neurons; summation of excitation and inhibition by postsynaptic neurons permits a neuron to integrate the electrical information provide ...
Neural Pathways and Transmission
Neural Pathways and Transmission

... the membrane of the neuron, causing a difference in charge across the membrane Potassium and sodium ions line the membrane in unequal distribution to cause a positive exterior and a negatively charged interior Potassium (K+) is concentrated on the interior of the cell, sodium (Na+) on the outside Wh ...
Neurons Short Version
Neurons Short Version

... Most of the surface and outer few millimeters is gray matter, while most of the inner tracts are composed of white matter (myelinated neurons).  Remember in the brain the outer layers are gray matter and the inner is white matter while in the spinal cord the outer layer is white matter and the inne ...
Ch33 nervous system reading essentials
Ch33 nervous system reading essentials

... Have you ever heard scary sounds in the middle of the night? Maybe your heart began to pound and your palms became sweaty. This type of reaction is involuntary—you do not think about it, it just happens. The autonomic nervous system is responsible for this reaction. The autonomic nervous system carr ...
The molecular mechanisms of general anaesthesia: dissecting the
The molecular mechanisms of general anaesthesia: dissecting the

... GABAA receptors are composed of pentameric arrangements of subunits around a central ion channel pore. Eighteen possible subunits including a1–6, b1–3, g 1–3, d, e, p, r1–3 subtypes have been identified in the mammalian genome. If there were no limitations to receptor assembly, then many thousands o ...
CHAPTER 2 –OUTLINE I. Introduction: Neuroscience and Behavior
CHAPTER 2 –OUTLINE I. Introduction: Neuroscience and Behavior

... called synaptic vesicles, which contain special chemical messengers called neurotransmitters. (2) The synaptic vesicles release the neurotransmitters into the synaptic gap. (3) Synaptic transmission is the process through which neurotransmitters are released by one neuron, cross the synaptic gap, an ...
chapter3 (new window)
chapter3 (new window)

... • If threshold is low, person has high contrast sensitivity. ...
Nervous system summary
Nervous system summary

... dopamine. Neurons may begin to reduce the number of dopamine receptors or simply make less dopamine. The result is less dopamine signaling in the brain—like turning down the volume on the dopamine signal. Because some drugs are toxic, some neurons also may die. As a result, the ability to feel any p ...
Therapeutic Restoration of Spinal Inhibition via
Therapeutic Restoration of Spinal Inhibition via

... Dysfunction of γ-Aminobutyric Acid (GABA)–ergic Signaling in the Superficial Dorsal Horn in Neuropathic PainIn normal function, nociceptive fibers innervate peripheral tissues and form excitatory (glutamatergic) synapses onto secondary sensory neurons in superficial laminae (I and II) of the dorsal ...
Biology 3201
Biology 3201

...  Neurons located near receptor organs (skin, eyes, ears). ...
Gene Section IL22RA1 (interleukin 22 receptor, alpha 1)
Gene Section IL22RA1 (interleukin 22 receptor, alpha 1)

... IL22RA1 is not detectable in normal immune cells, including monocytes, B-cells, T-cells, natural killer cells, macrophages and dendritic cells, cell types that are normally found in the bone marrow, peripheral blood, thymus and spleen. ...
Solutions to 7
Solutions to 7

... i) What are two main differences between prokaryotic cells and eukaryotic cells? Prokaryotic cells lack nucleus whereas eukaryotic cells have a nucleus. Prokaryotic cells are evolutionarily more ancient than eukaryotic cells. Eukaryotic cells have organelles and internal memebranes, prokaryotic cell ...
Nervous System
Nervous System

... Explain the general functions (3 Functions) of the nervous system. Identify the two main parts of the Nervous System Describe the structure of a neuron and the function of each major part. Distinguish between sensory neurons, motor neurons, and interneurons. Summarize the electrical and chemical con ...
Nervous System
Nervous System

... Sensory: This function of the system includes collecting information from sensory receptors that monitor the body’s internal and external condition. Integration: This is the function of processing many sensory signals that come through the CNS at a given time. Motor: This function happens once the C ...
Chapter 27
Chapter 27

... monosynaptic: the reflex arc has only 1 synapse between the sensory & motor neurons in the spinal cord polysynaptic: reflexes involving two or more synapses ...
The Nervous System workbooklet
The Nervous System workbooklet

... The brain has billions of neurons that receive, analyse, and store information about internal and external conditions. It is also the source of conscious and unconscious thoughts, moods, and emotions. Four major brain divisions govern its main functions: the cerebrum, the diencephalon, the cerebellu ...
conductance versus current-based integrate-and - Neuro
conductance versus current-based integrate-and - Neuro

... currents are hard to handle analytically and it has been difficult to gain insight into the quantitative behaviour of ensembles of such neurons. A much-simplified model neuron, the integrate-and-fire (IF) neuron captures many of the broad features that biological neurons share and has become a stand ...
Vanadium: Insulin Mimicry
Vanadium: Insulin Mimicry

... How does insulin work? ...
The Autonomic Nervous System - Ashland Independent Schools
The Autonomic Nervous System - Ashland Independent Schools

... • Axons of motor nerves (from T1-L2) exit through ventral root of spinal nerves, branch and enter sympathetic ganglia (trunks) located in chains along vertebral column – Sympathetic preganglionic neurons exit the spinal cord only between levels T1-L2 • Short pre-ganglionic fiber releases acetylcholi ...
Sensory Pathways and the Somatic Nervous System
Sensory Pathways and the Somatic Nervous System

... 15-1 Specify the components of the afferent and efferent divisions of the nervous system, and explain what is meant by the somatic nervous system. 15-2 Explain why receptors respond to specific stimuli, and how the organization of a receptor affects its sensitivity. 15-3 Identify the receptors for t ...
Biological Bases of Behavior : Quiz 1
Biological Bases of Behavior : Quiz 1

... The release of transmitter substance into the synaptic cleft depends on a. a second messenger. b. deactivation of the sodium-potassium pump. c. the influx of calcium ions from the extracellular fluid. d. the opening of microtubules. ...
Biology Option E
Biology Option E

... E.1.2 State that innate behavior develops independently of the environmental context, whereas learned behavior reflects conditions experienced by individuals during development. Innate behavior develops independently of the environmental context, whereas learned behavior reflects conditions experie ...
Chapter 10 . Adrenoceptor Agonists :
Chapter 10 . Adrenoceptor Agonists :

... act on D1 receptor, dilate At high concentration : act on αreceptor, constrict ...
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Endocannabinoid system

The endocannabinoid system is a group of neuromodulatory lipids and their receptors in the brain that are involved in a variety of physiological processes including appetite, pain-sensation, mood, and memory; it mediates the psychoactive effects of cannabis and, broadly speaking, includes: The endogenous arachidonate-based lipids, anandamide (N-arachidonoylethanolamide, AEA) and 2-arachidonoylglycerol (2-AG); these are known as ""endocannabinoids"" and are physiological ligands for the cannabinoid receptors. Endocannabinoids are all eicosanoids. The enzymes that synthesize and degrade the endocannabinoids, such as fatty acid amide hydrolase or monoacylglycerol lipase. The cannabinoid receptors CB1 and CB2, two G protein-coupled receptors that are located in the central and peripheral nervous systems.The neurons, neural pathways, and other cells where these molecules, enzymes, and one or both cannabinoid receptor types are all colocalized form the endocannabinoid system.The endocannabinoid system has been studied using genetic and pharmacological methods. These studies have revealed that cannabinoids act as neuromodulators for a variety of processes, including motor learning, appetite, and pain sensation, among other cognitive and physical processes. The localization of the CB1 receptor in the endocannabinoid system has a very large degree of overlap with the orexinergic projection system, which mediates many of the same functions, both physical and cognitive. Moreover, CB1 is colocalized on orexin projection neurons in the lateral hypothalamus and many output structures of the orexin system, where the CB1 and orexin receptor 1 (OX1) receptors physically and functionally join together to form the CB1–OX1 receptor heterodimer.
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