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Lecture PPT - Carol Eunmi LEE
Lecture PPT - Carol Eunmi LEE

... • Ancestral gene resurrection demonstrates that long before the hormone evolved, the receptor’s affinity for aldosterone was present due to its similarity to more ancient ligands (probably DOC) – also, ancestral receptor was less specific… • Two amino acid changes in the ancestral sequence resulted ...
Chapter 02: Neurons and Glia
Chapter 02: Neurons and Glia

... adapt their behavior to the setting in which they live Can have many causes Genetic disorders such as PKU or Down syndrome Accidents or infection during pregnancy or early childhood Poor nutrition during pregnancy Environmental impoverishment such as the lack of good nutrition, socialization, Fig A ...
M555 Medical Neuroscience
M555 Medical Neuroscience

... is orthostatic hypotension. In fact, blood pressure regulation overall is faulty. Sometimes while reclining, R.K.’s blood pressure rises dramatically. R.K. also experience irregular heartbeat, constipation, incontinence and dimished ability to control body temperature. In addition, there are signs s ...
03/05 PPT
03/05 PPT

... • Different cells respond to the same guidance cues in different ways • Chemical cues exist at many points along the axon guidance pathway e.g the optic tectum and optic tract ...
SYNAPTIC TRANSMISSION
SYNAPTIC TRANSMISSION

... 4. If successfully transmitted, the nerve impulse is then carried along the post-synaptic neuron until it reaches the next synaptic terminal where the message will continue to pass on via electrical ...
Sense Organs
Sense Organs

... a. Stimulus must initiate an action potentia l in the cerebral cortex 3. The brain interprets these impulses as sound or sight even though the impulses themselves are identical in nature. 4. The cerebral cortex screens the information and ignores most of what it receives. C. Our senses act as energy ...
Lecture 18: Sensation
Lecture 18: Sensation

... 1. General sensation relies on sensory receptors that are widely distributed throughout the body. A. Usually. general sensory receptors are the dendrites of a sensory neuron. B. There are a diverse set of different kinds of general receptors, including free dendrites (pain, hair movement, light t ...
NEURAL REGULATION OF RESPIRATION LEARNING
NEURAL REGULATION OF RESPIRATION LEARNING

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The Molecular Logic of Smell

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Alkaloids - Faculty Pages

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Lecture 16
Lecture 16

... Leaky integrate and fire neurons Encode each individual spike Time is represented exactly Each spike has an associated time The timing of recent incoming spikes determines whether a neuron will fire • Computationally expensive • Can we do almost as well without encoding every single spike? ...
The Signal - WM Keck Center for Behavioral Biology
The Signal - WM Keck Center for Behavioral Biology

... Lomvardas began by highlighting that he uses genetic tools to study regulation of expression of olfactory receptors within mouse olfactory neurons. He explained that development is orchestrated by genetically hardwired signaling gradients, which in different tissues activate sets of transcription fa ...
Central Nervous System
Central Nervous System

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Questions for Exam #3

... patch, you can detect a current in response to heat (over 40oC) or capsaicin. If you record from a detached patch, you also detect a current in response to heat. (For more complete description, see last page.) C-1. From these results, it is likely that the heat receptor proteins of the worm are (ion ...
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Ch 3 (30 MCQ answers)

... liken action potentials to the digital signals in a computer. But this vastly underestimates the complexity of the nervous system and the potential subtlety of its responses. In fact, the propagation of the action potential may be all or nothing, but its effect can be very subtly graded. 18) Answer: ...
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PROGRAM AND ABSTRACTS CATALYST FOR COLLABORATION AT EAST CAROLINA: TODAY AND TOMORROW

... involving its extracellular (EC) domain. The EC domain can be cleaved in normal brain by a disintegrin and metalloprotease ADAM10, releasing a soluble fragment that acts as a dominant negative to perturb NCAM function. Ectodomain shedding of NCAM in neurons is normally regulated by tyrosine kinase a ...
Chapter 18
Chapter 18

... PET scan on the left shows two areas of the brain (red and yellow) that become particularly active when volunteers read words on a video screen: the primary visual cortex and an additional part of the visual system, both in the back of the left hemisphere. Other brain regions become especially activ ...
Biological Bases of Behavior - Mrs. Short`s AP Psychology Class
Biological Bases of Behavior - Mrs. Short`s AP Psychology Class

... – the neural message being delivered in a synaptic transmission is carried across the synaptic gap by ...
Visceral Nervous System
Visceral Nervous System

... RADICULAR NEURONS: they form the anterior roots. In the spinal cord the cell body is in the anterior horn of the grey metter; in the brain stem in motor nuclei. FASCICULAR NEURONS: they represent the second neuron of a sensory pathway. In the spinal cord the cell body is in the posterior horn of the ...
Competitive Learning Lecture 10
Competitive Learning Lecture 10

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Glands

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CHAPTER 2 outline
CHAPTER 2 outline

... called synaptic vesicles, which contain special chemical messengers called neurotransmitters. (2) The synaptic vesicles release the neurotransmitters into the synaptic gap. (3) Synaptic transmission is the process through which neurotransmitters are released by one neuron, cross the synaptic gap, an ...
B6 – Brain and mind - The Bicester School
B6 – Brain and mind - The Bicester School

... that can increase an animal’s chance of survival.  In some circumstances the brain can modify a reflex response via a neuron to the motor neuron of the reflex arc, for example keeping hold of a ...
touch and pain - Stark home page
touch and pain - Stark home page

... Lower limbs medial in gracile tract. Upper limbs lateral in cuneate tract. ipsilateral projection First nucleus is in lower medulla There is a cross-over, and then the next nucleus is in the thalamus. •  This lemnicsal system is evolutionarily "new" (reptiles and above) and is for localized touch. ...
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Endocannabinoid system

The endocannabinoid system is a group of neuromodulatory lipids and their receptors in the brain that are involved in a variety of physiological processes including appetite, pain-sensation, mood, and memory; it mediates the psychoactive effects of cannabis and, broadly speaking, includes: The endogenous arachidonate-based lipids, anandamide (N-arachidonoylethanolamide, AEA) and 2-arachidonoylglycerol (2-AG); these are known as ""endocannabinoids"" and are physiological ligands for the cannabinoid receptors. Endocannabinoids are all eicosanoids. The enzymes that synthesize and degrade the endocannabinoids, such as fatty acid amide hydrolase or monoacylglycerol lipase. The cannabinoid receptors CB1 and CB2, two G protein-coupled receptors that are located in the central and peripheral nervous systems.The neurons, neural pathways, and other cells where these molecules, enzymes, and one or both cannabinoid receptor types are all colocalized form the endocannabinoid system.The endocannabinoid system has been studied using genetic and pharmacological methods. These studies have revealed that cannabinoids act as neuromodulators for a variety of processes, including motor learning, appetite, and pain sensation, among other cognitive and physical processes. The localization of the CB1 receptor in the endocannabinoid system has a very large degree of overlap with the orexinergic projection system, which mediates many of the same functions, both physical and cognitive. Moreover, CB1 is colocalized on orexin projection neurons in the lateral hypothalamus and many output structures of the orexin system, where the CB1 and orexin receptor 1 (OX1) receptors physically and functionally join together to form the CB1–OX1 receptor heterodimer.
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