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Chapter 5: sensation PAGE 1 Table 1: Sensing the World: Some
Chapter 5: sensation PAGE 1 Table 1: Sensing the World: Some

... thickness of the lens change to bring either nearby or distant objects into focus on the retina. Light rays travel in straight lines. So rays from the top of the candle strike the bottom of the retina and those from the left side of the candle strike the right side of the retina. The candle’s retina ...
Document
Document

... in many areas of the brain. It apparently does this by inhibiting the release of neurotransmitters, chemicals that carry nerve impulses from one neuron to the next. (10) Like many other agents that affect neuron firing, adenosine must first bind to specific receptors on neuronal membranes. There are ...
Chemistry of Opioids
Chemistry of Opioids

... o Partial agonist activity @ μ receptor due to metabolite nor-buprenorphine o Partial antagonist activity@ κ receptor o Antihyperalgesic effect: κ receptor antagonistic activity o ↓Adverse effects: ↓respiratory depression, not altered by age or renal dysfunction Meperidine o Binds to P-site: phenoli ...
Neurons and Neurotransmitters
Neurons and Neurotransmitters

... neuron which sends messages from the soma to other neuron. Longest part of the neuron. (Think “axis” … a long line.) ...
17- The Nervous System: The Basic Structure
17- The Nervous System: The Basic Structure

Nervous System Cells - Dr. M`s Classes Rock
Nervous System Cells - Dr. M`s Classes Rock

...  Synaptic knob: tiny bulge at the end of a terminal branch of a presynaptic neuron’s axon that contains vesicles housing neurotransmitters  Synaptic cleft: space between a synaptic knob and the plasma membrane of a postsynaptic neuron  Plasma membrane of a postsynaptic neuron has protein molecule ...
TyrPhos12
TyrPhos12

... • Tyr phosphorylation allows recruitment of proteins that possess domains that bind to specific peptide sequences that encompass a phosphorylated tyr and which  activating a variety of signalling pathways. • Such domains include SH2 and SH3 and P-tyr binding (PTB) domains. • These domains bind to t ...
THE NERVOUS SYSTEM I
THE NERVOUS SYSTEM I

... carries information away from the cell body. ...
The Nervous System
The Nervous System

... to a nerve impulse. • A resting neuron is polarized. There are more Na+ outside and less K+ inside. • Stimuli causes the permeability of the plasma membrane to change, changing the polarity. ...
physiological role of neuropeptide y in sympathetic neurotransmission
physiological role of neuropeptide y in sympathetic neurotransmission

... frequency of nerve stimulation. The Y2 agonists not only inhibited the evoked release of NE but also the nerve stimulation induced increase in perfusion pressure. In contrast Y1 selective agonists facilitated the increase in perfusion pressure. In contrast to the prejunctional inhibitory effect of N ...
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Addressing of 5-HT1A and 5-HT1B receptors

Local Copy - Synthetic Neurobiology Group
Local Copy - Synthetic Neurobiology Group

... learned only through experimentation—perturbing things, then seeing what happens next. So it is with cells: Once roused or stifled, cells may reveal much that would otherwise remain hidden. The idea is to enact “what if” scenarios instead of simply watching and waiting. The trick, however, is to per ...
Physiology Ch 45 p543-557 [4-25
Physiology Ch 45 p543-557 [4-25

... Effect of Inhibitory Synapses on Postsynaptic Membrane – inhibitory synapses open chloride channels to allow easy passage. Nernst potential for Cl is -70mV which is more negative than 65mV inside membrane, and so opening Cl channels will make interior more negative -opening of K channels will allow ...
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7. MODELING THE SOMATOTOPIC MAP 7.1 The Somatotopic Map

... image area in the somatosensory cortex. Interestingly, the neural projections giving rise to these images are not rigid. Instead, they can change under the influence of sensory experience or as the result of a loss of sensory input, e.g., after nerve damage. The necessary modifications of the connec ...
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No Slide Title

... ARTERIAL pH • VARIATIONS OF PaO2 <3-4 mm Hg AND EVEN LESS FOR PaCO2 • TO EXPEND MINIMAL ENERGY IN THE WORK OF BREATHING ...
Neuron communication
Neuron communication

... Schizophrenia have 6x the proper level of dopamine!) • Agonists: mimic neurotransmitters when you don’t have enough (ex: Depression is caused by low levels of serotonin.) ...
Answer Key Chapter 28 - Scarsdale Public Schools
Answer Key Chapter 28 - Scarsdale Public Schools

THE NEURON (Slides 4 to 14) • Based on the PowerPoint attached
THE NEURON (Slides 4 to 14) • Based on the PowerPoint attached

... A neuron is resting when its membrane forms a partial barrier between the inside and outside of the neuron. The solution contains electrically charged particles called ions. When the neuron is at rest, there are more negative ions on the outside which is called the resting potential. A resting neuro ...
Nervous System
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... Autonomic Nervous System (ANS) Sympathetic Nervous System: Division of the ANS that arouses the body, mobilizing its energy in stressful situations. Parasympathetic Nervous System: Division of the ANS that calms the body, conserving its energy. ...
Chapter 9 Senses - msubillings.edu
Chapter 9 Senses - msubillings.edu

... rods have open ligandgated sodium (Na + ) channels (bound ligand is cyclic quanosine monophosphate (cGMP)) that allow a continual flow of sodium into the cell, at the same time the sodium-potassium-pump (3Na + out 2K + in) is working, creating what’s called the dark current, causing a constant state ...
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Slide 1

... regions. The antenna containing olfactory neurons is in light blue, and the first relay, the antenna lobes, is in dark blue. Neurons with the same receptor project to a single glomerulus. A single projection neuron innervates one glomerulus and sends axons to the protocerebrum. B. Olfactory neurons ...
Introduction to the physiology of perception
Introduction to the physiology of perception

... Transmission of Neural Impulses across the gap • An action potential is passed on to the next neuron through a synapse • A synapse is a process that releases neurotransmitters, chemicals stored in the synaptic vesicles (cavities) of the sending neuron • In a synapse, an action potential cause neurot ...
Growth Hormones
Growth Hormones

... and the insulin receptor) to stimulate growth. The type-I IGF receptor is similar to the insulin receptor, with intrinsic tyrosine kinase activity. Binding of IGFs to their receptors results in phosphorylation of insulin-responsive substrates (IRSs), which stimulate tissue growth and differentiation ...
The Nervous System
The Nervous System

... (12 pairs of cranial nerves and 31 pairs of spinal nerves), which serve as linkage between the CNS and the body. 4. PNS can be subdivided into Sensory (afferent) nerves and Motor (efferent) nerves. Sensory nerves send nerve impulse from the body to CNS, while motor nerves send impulse from CNS to ef ...
CLASS #1: 9 Jan 2001
CLASS #1: 9 Jan 2001

... by post-synaptic neuron; ● glial uptake; ● enzyme deactivation. D. Actions at post-synaptic membrane: If receptors in post-synaptic membrane recognize the transmitter (=ligand-gated channels), the membrane’s conformation changes, causing a change in ion movement across the post-synaptic membrane and ...
< 1 ... 123 124 125 126 127 128 129 130 131 ... 206 >

Endocannabinoid system

The endocannabinoid system is a group of neuromodulatory lipids and their receptors in the brain that are involved in a variety of physiological processes including appetite, pain-sensation, mood, and memory; it mediates the psychoactive effects of cannabis and, broadly speaking, includes: The endogenous arachidonate-based lipids, anandamide (N-arachidonoylethanolamide, AEA) and 2-arachidonoylglycerol (2-AG); these are known as ""endocannabinoids"" and are physiological ligands for the cannabinoid receptors. Endocannabinoids are all eicosanoids. The enzymes that synthesize and degrade the endocannabinoids, such as fatty acid amide hydrolase or monoacylglycerol lipase. The cannabinoid receptors CB1 and CB2, two G protein-coupled receptors that are located in the central and peripheral nervous systems.The neurons, neural pathways, and other cells where these molecules, enzymes, and one or both cannabinoid receptor types are all colocalized form the endocannabinoid system.The endocannabinoid system has been studied using genetic and pharmacological methods. These studies have revealed that cannabinoids act as neuromodulators for a variety of processes, including motor learning, appetite, and pain sensation, among other cognitive and physical processes. The localization of the CB1 receptor in the endocannabinoid system has a very large degree of overlap with the orexinergic projection system, which mediates many of the same functions, both physical and cognitive. Moreover, CB1 is colocalized on orexin projection neurons in the lateral hypothalamus and many output structures of the orexin system, where the CB1 and orexin receptor 1 (OX1) receptors physically and functionally join together to form the CB1–OX1 receptor heterodimer.
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