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Introduction of the Nervous System
Introduction of the Nervous System

... the cerebrum where conscious thoughts are initiated. In humans: the polysynaptic reflex is the sudden movement to protect life and limb. An example usually given is walking in a shallow pond and stepping on a sharp object. The foot immediately raises before you are voluntarily aware of pending dange ...
Receptor potential
Receptor potential

... tendency of some sensory receptors to become less sensitive when they are stimulated repeatedly. ...
Peripheral Nervous System
Peripheral Nervous System

... The nervous system gathers information from inside and outside of the body, responds to the information that it gathers and helps to maintain homeostasis. • A change in the environment causes an organism to react called a stimulus. • The nervous system will then examine the information from the stim ...
Biology of the Mind Neural and Hormonal Systems
Biology of the Mind Neural and Hormonal Systems

... ▪ tiny gap at this junction is called the synaptic gap or cleft ...
Physiology SENSORY PHYSIOLOGY Sensory Receptors Martin Paré
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... How is a stimulus converted into a neural signal? Answer: The stimulus opens ion channels in the receptor membrane, either directly or indirectly (through a second messenger). In most cases, channel opening results in net influx of Na+ into the receptor, causing a depolarization of the membrane. In ...
1 Preface Dear Psychology Students, Anyone can
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... science. He and his peers believed that animals learn by reacting to environmental experiences or stimuli. Therefore they were trying to predict behavioral responses to a stimuli. Mental states, feelings or thoughts were basically of no interest to behaviorists, as long as you could not observe them ...
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11 - Dr. Jerry Cronin

... • Ligand-gated ion channels • Action is immediate and brief • Excitatory receptors are channels for small ...
53 XIX BLY 122 Lecture Notes (O`Brien)
53 XIX BLY 122 Lecture Notes (O`Brien)

... (K+), and Chloride (Cl–) ions are at equilibrium ...
Chapter 6 - IFSC-USP
Chapter 6 - IFSC-USP

... euphoria, relaxation, and eventually addiction (Box A), effects believed to be mediated in this case by nAChRs. Nicotinic receptors are the beststudied type of ionotropic neurotransmitter receptor. As described in Chapter 5, nAChRs are nonselective cation channels that generate excitatory postsynapt ...
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... Protease activated receptor-1 (PAR-1) is part of a family of receptors that use thrombin as the signaling protein. PAR-1 has already been shown to lead to apoptosis of motor neurons found in the spinal cord, although the specific mechanism of cell death is not completely understood. While motor neur ...
The Nervous System
The Nervous System

...  Uses motor neurons to carry signals from CNS to other ...
The Nervous System and the Brain
The Nervous System and the Brain

... overreacts. In the absence of external threats, their bodies still respond as if they were faced with danger, such as in anxiety or panic attacks. ...
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review glutamate and gaba receptor signalling in - lópez

... in recent years. The major excitatory and inhibitory neurotransmitters in the brain, glutamate and GABA, activate both ionotropic (ligand-gated ion channels) and metabotropic (G protein-coupled) receptors, and are generally associated with neuronal communication in the mature brain. However, before ...
P2 Receptor Antagonist Trinitrophenyl-Adenosine
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... involves a pronounced reduction in intracellular oxygen and glucose, which leads to rapid cell death associated with Ca2⫹, Na⫹, K⫹, and Cl⫺ deregulation. In particular, the increase of Ca2⫹ influx can directly control the activation of proteolytic enzymes and apoptotic genes and the production of re ...
Handout - Science in the News
Handout - Science in the News

... Studying the brain is like learning a foreign language – the language by which neurons communicate. Neuroscientists have made great progress by listening in on the neurons’ conversations. But, to be sure that we understand their language correctly, we have to be able to talk back to the neurons and ...
The Nervous System
The Nervous System

... -Interneurons are found only in the central nervous system where they connect neuron to neuron. -They are stimulated by signals reaching them from sensory neurons, other interneurons or both. -are also called association neurons. -It is estimated that the human brain contains 100 billion (1011) inte ...
Sensory Systems and Neural Circuits II
Sensory Systems and Neural Circuits II

... •  Foods that are sour have high acidity (low pH) •  When acids are dissolved in water, they generate H+ ions •  H+ ions pass through the same channel that Na+ does •  H+ blocks a K+ channel as well •  The net movement of cations into the cell depolarizes the taste cell •  This opens a Ca2+ channel ...
neuron
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... • Neurons usually do not touch each other or other cells • A small gap, called a synaptic cleft, is present between the axon terminal and the receiving cell • Electrical activity in the neuron usually causes the release of chemicals called neurotransmitters into the synaptic cleft ...
Anat 1: Ch 17 (SS99)
Anat 1: Ch 17 (SS99)

... short axons in adrenal medulla to release NT into blood stream (= hormones) ...
1 Revised 10/11/2016 The Physiology of the Senses Lecture 7
1 Revised 10/11/2016 The Physiology of the Senses Lecture 7

... As with retinal ganglion cells, a stimulus in the center of a cell’s receptive field will activate the DCN neuron while a stimulus in the surround, through inhibitory feedback, will inhibit the same DCN neuron (Figure 7.17). Receptive fields, with an inhibitory surround, first occurs in the DCN, not ...
Synaptogenesis
Synaptogenesis

... BDNF and NGF, which bind to the low-affinity neurpotrophin receptor p75 and help sustain regenerating axons and guide them to their targets. Schwann cells and macrophages also synthesize apolipoprotein E (ApoE), which may help promote neuron survival and axon regrowth. ...
Neurons and Neurotransmitters
Neurons and Neurotransmitters

... History of Biological Psychology • Plato was the first to suggest that the mind was in the head. • In the 1800’s, Franz Gall proposed phrenology - studying bumps on the head for character traits and suggesting different parts of the brain control different aspects of ...
A REVIEW ON THE PHARMACOLOGY AND TOXICOLOGY OF ACETYLCHOLINE RECEPTORS... THE NEUROMUSCULAR JUNCTION  Original Article
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... It is a disorder which is characterized with the following symptoms like distraction and impetuosity and the treatment involves Pemoline, Amphetamine and Methyl phenidate acting through dopamine transmission [2]. Since Nicotine Agonists enhance the cognitive behavior, novel drugs such as 2-Nicotine ...
Slide 1 - Elsevier
Slide 1 - Elsevier

... channel, and a Ca2+/calmodulin (CaM)-mediated desensitization of the CNG channel that underlies rapid odor adaptation. Several other mechanisms have also been described, including phosphodiesterase-mediated hydrolysis of the second messenger cAMP and phosphorylation of the OR by various kinases. ...
Chapter 21
Chapter 21

... a. a muscle spindle consists of 3 to 10 intrafusal muscle fibers that are enclosed in a spindleshaped connective tissue capsule; surrounding a muscle spindle are extrafusal (i.e., regular) muscle fibers b. the central area of an intrafusal fiber is innervated by two types of afferent fibers which de ...
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Endocannabinoid system

The endocannabinoid system is a group of neuromodulatory lipids and their receptors in the brain that are involved in a variety of physiological processes including appetite, pain-sensation, mood, and memory; it mediates the psychoactive effects of cannabis and, broadly speaking, includes: The endogenous arachidonate-based lipids, anandamide (N-arachidonoylethanolamide, AEA) and 2-arachidonoylglycerol (2-AG); these are known as ""endocannabinoids"" and are physiological ligands for the cannabinoid receptors. Endocannabinoids are all eicosanoids. The enzymes that synthesize and degrade the endocannabinoids, such as fatty acid amide hydrolase or monoacylglycerol lipase. The cannabinoid receptors CB1 and CB2, two G protein-coupled receptors that are located in the central and peripheral nervous systems.The neurons, neural pathways, and other cells where these molecules, enzymes, and one or both cannabinoid receptor types are all colocalized form the endocannabinoid system.The endocannabinoid system has been studied using genetic and pharmacological methods. These studies have revealed that cannabinoids act as neuromodulators for a variety of processes, including motor learning, appetite, and pain sensation, among other cognitive and physical processes. The localization of the CB1 receptor in the endocannabinoid system has a very large degree of overlap with the orexinergic projection system, which mediates many of the same functions, both physical and cognitive. Moreover, CB1 is colocalized on orexin projection neurons in the lateral hypothalamus and many output structures of the orexin system, where the CB1 and orexin receptor 1 (OX1) receptors physically and functionally join together to form the CB1–OX1 receptor heterodimer.
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