Cytokine responses in metal-induced allergic contact in Jacob Taku Minang
... 1984, Braciale et al., 1987). There are two distinct subpopulations of T cells within the α/β TcR expressing lymphocytes defined based on their surface expression of either CD4 or CD8 in combination with the accessory marker CD3 (de Gast et al., 1985). The CD4+ T cells, designated T-helper (Th) cell ...
... 1984, Braciale et al., 1987). There are two distinct subpopulations of T cells within the α/β TcR expressing lymphocytes defined based on their surface expression of either CD4 or CD8 in combination with the accessory marker CD3 (de Gast et al., 1985). The CD4+ T cells, designated T-helper (Th) cell ...
2、role of autophagy in plant innate immunity
... nutrient starvation and pathogen infection . plant ATG genes are upregulated during nitrogen starvation consistent with their function in senescence and hypersensitivity to nutrients Interestingly, these genes are also regulated during defence responses to pathogens. Several AtATG genes are upregula ...
... nutrient starvation and pathogen infection . plant ATG genes are upregulated during nitrogen starvation consistent with their function in senescence and hypersensitivity to nutrients Interestingly, these genes are also regulated during defence responses to pathogens. Several AtATG genes are upregula ...
innate immunity in c. elegans
... C‑type lectins are carbohydrate‑binding proteins that can exhibit very narrow ligand specificity. In mammals, a number of C‑type lectins have established roles in innate immunity. For example, Dectin‑1 is highly expressed on macrophages and recognizes beta‑glucan, a component of the fungal cell wall ...
... C‑type lectins are carbohydrate‑binding proteins that can exhibit very narrow ligand specificity. In mammals, a number of C‑type lectins have established roles in innate immunity. For example, Dectin‑1 is highly expressed on macrophages and recognizes beta‑glucan, a component of the fungal cell wall ...
Here - European Macrophage and Dendritic Cell Society
... beautiful bridges and fountains, a five kilometer long historic city wall from the 15th/16th century almost completely surrounding the old town and the majestic Imperial Castle attract more than 35 million tourists a year. For close to 500 years, the Imperial Castle, dating back to before the year 1 ...
... beautiful bridges and fountains, a five kilometer long historic city wall from the 15th/16th century almost completely surrounding the old town and the majestic Imperial Castle attract more than 35 million tourists a year. For close to 500 years, the Imperial Castle, dating back to before the year 1 ...
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... as a substrate. Furthermore, the bacterial signals produced by B. thetaiotaomicron induce the production of intestinal mucosal glycans. Adaptations of E. rectale in response to B. thetaiotaomicron include decreased production of its glycan-degrading enzymes and increased expression of selected amino ...
... as a substrate. Furthermore, the bacterial signals produced by B. thetaiotaomicron induce the production of intestinal mucosal glycans. Adaptations of E. rectale in response to B. thetaiotaomicron include decreased production of its glycan-degrading enzymes and increased expression of selected amino ...
Lymphomas Involving Waldeyer`s Ring
... Since the current WHO lymphoma classification does not require sub-categorisation of diffuse large B-cell lymphomas, numbers are large probably because this group is heterogeneous and incorporates more than 1 disease entity, as suggested by the presence of differences in gene expression profile and ...
... Since the current WHO lymphoma classification does not require sub-categorisation of diffuse large B-cell lymphomas, numbers are large probably because this group is heterogeneous and incorporates more than 1 disease entity, as suggested by the presence of differences in gene expression profile and ...
Syddansk Universitet Immunogenicity and Immune
... Immunogenicity concerns focus on the presentation of antigens and expression of MHC class I proteins, as well as expression of molecules that make hESC potential targets of cytotoxic responses by T and NK cells. Almost all cellular studies dealing with HLA class I expression have relied on a single ...
... Immunogenicity concerns focus on the presentation of antigens and expression of MHC class I proteins, as well as expression of molecules that make hESC potential targets of cytotoxic responses by T and NK cells. Almost all cellular studies dealing with HLA class I expression have relied on a single ...
3 - bioRxiv
... coming from their neighbours or from their own autocrine signals [14, 15]. Since the adaptation to the environment occurs at the population level, autocrine and paracrine feedback may play a different role in a cell population responding to opposing signals, notably as a function of cell density. De ...
... coming from their neighbours or from their own autocrine signals [14, 15]. Since the adaptation to the environment occurs at the population level, autocrine and paracrine feedback may play a different role in a cell population responding to opposing signals, notably as a function of cell density. De ...
The Influence of Melatonin on Immune System and Cancer
... reactive oxygen species (ROS) in macrophages, which enhances their phagocytic potential [16,17]. The effect of melatonin on NK-cells is important because these cells are assumed to play a significant part in immune surveillance against early cancer development and viral infection [18]. Besides featu ...
... reactive oxygen species (ROS) in macrophages, which enhances their phagocytic potential [16,17]. The effect of melatonin on NK-cells is important because these cells are assumed to play a significant part in immune surveillance against early cancer development and viral infection [18]. Besides featu ...
Early steps regulating proliferation and activation in macrophages Ester Sánchez Tilló 2006
... response contributes to an efficient control of growth and dissemination of invading pathogens. Conversely, products induced by LPS can act as intracellular or extracellular messengers. On the other hand, IFN-γ promotes inhibition of proliferation increasing macrophage survival together with up-regu ...
... response contributes to an efficient control of growth and dissemination of invading pathogens. Conversely, products induced by LPS can act as intracellular or extracellular messengers. On the other hand, IFN-γ promotes inhibition of proliferation increasing macrophage survival together with up-regu ...
Assessing Bacterial Interactions Using Carbohydrate-Based
... Carbohydrates play a crucial role in a wide variety of biological processes such as cell-cell recognition, metastasis, immune system mediation and function, intracellular trafficking and progression of many diseases including cancer [1,2]. They are also critically important in host-microorganism int ...
... Carbohydrates play a crucial role in a wide variety of biological processes such as cell-cell recognition, metastasis, immune system mediation and function, intracellular trafficking and progression of many diseases including cancer [1,2]. They are also critically important in host-microorganism int ...
Plasma membrane
... • Small hair-like extensions • Cilia move fluids across the cell surface © 2012 Pearson Education, Inc. ...
... • Small hair-like extensions • Cilia move fluids across the cell surface © 2012 Pearson Education, Inc. ...
Activation of cytokines corroborate with development of
... immune cell subsets and tissues, and have a particularly critical role in modulating both the innate and adaptive immune responses. Both a deficiency and an excess of cytokine production, as well as unusual responsiveness of immune cells to cytokines, can favour the development of immune-mediated di ...
... immune cell subsets and tissues, and have a particularly critical role in modulating both the innate and adaptive immune responses. Both a deficiency and an excess of cytokine production, as well as unusual responsiveness of immune cells to cytokines, can favour the development of immune-mediated di ...
COMPARISON OF CYCLOSPORIN A WITH MITOMYCINC AND GAMMA
... produced during the MLC depends on the number of disparities in the MLC between donor and recipient, which will be different for each MLC reaction. Since the number of allogeneic T cells involved in the MLC reaction is not known, the amount of IL-2 produced during the allogeneic immune response in t ...
... produced during the MLC depends on the number of disparities in the MLC between donor and recipient, which will be different for each MLC reaction. Since the number of allogeneic T cells involved in the MLC reaction is not known, the amount of IL-2 produced during the allogeneic immune response in t ...
English - SciELO Costa Rica
... membrane protein B (rOmpB or sca5) binds to the host cell membrane form of Ku70.57 Since blocking of this interaction only inhibits about 50% of rickettsial entry, other ligands and receptors must be present; sca258 and adr259 appear to be some of those bacterial ligands. The necessary cytoskeletal ...
... membrane protein B (rOmpB or sca5) binds to the host cell membrane form of Ku70.57 Since blocking of this interaction only inhibits about 50% of rickettsial entry, other ligands and receptors must be present; sca258 and adr259 appear to be some of those bacterial ligands. The necessary cytoskeletal ...
Augmenting the First Line of Defense in Gastrointentinal
... responses and modulate systemic immunity. However, in context of bacterial relationships with intestinal PRRs, the feature that has attracted intense interest is ability of the gastrointestinal innate immune apparatus to modulate their responses between immune activation (against pathogens) vs. immu ...
... responses and modulate systemic immunity. However, in context of bacterial relationships with intestinal PRRs, the feature that has attracted intense interest is ability of the gastrointestinal innate immune apparatus to modulate their responses between immune activation (against pathogens) vs. immu ...
poster - Natural Killer Cell Symposium
... Natural killer (NK) cells are lymphocytes of the innate immune system that deliver a selective cytotoxic effect against target cells such as virally infected and tumor cells. NK cell function involves cytokine secretion and tissue remodeling. NK cellular cytotoxicity is delicately balanced by signal ...
... Natural killer (NK) cells are lymphocytes of the innate immune system that deliver a selective cytotoxic effect against target cells such as virally infected and tumor cells. NK cell function involves cytokine secretion and tissue remodeling. NK cellular cytotoxicity is delicately balanced by signal ...
Serum Dioxin and Immunologic Response in Veterans of Operation
... four antigen responses was positive, the composite skin test was scored as possibly abnormal. If one or more of the four antigen responses were positive, the composite skin test was considered normal, indicating intact cell-mediated immunity. Immunologic tests performed on blood were selected to scr ...
... four antigen responses was positive, the composite skin test was scored as possibly abnormal. If one or more of the four antigen responses were positive, the composite skin test was considered normal, indicating intact cell-mediated immunity. Immunologic tests performed on blood were selected to scr ...
Polyclonal B cell response
Polyclonal B cell response is a natural mode of immune response exhibited by the adaptive immune system of mammals. It ensures that a single antigen is recognized and attacked through its overlapping parts, called epitopes, by multiple clones of B cell.In the course of normal immune response, parts of pathogens (e.g. bacteria) are recognized by the immune system as foreign (non-self), and eliminated or effectively neutralized to reduce their potential damage. Such a recognizable substance is called an antigen. The immune system may respond in multiple ways to an antigen; a key feature of this response is the production of antibodies by B cells (or B lymphocytes) involving an arm of the immune system known as humoral immunity. The antibodies are soluble and do not require direct cell-to-cell contact between the pathogen and the B-cell to function.Antigens can be large and complex substances, and any single antibody can only bind to a small, specific area on the antigen. Consequently, an effective immune response often involves the production of many different antibodies by many different B cells against the same antigen. Hence the term ""polyclonal"", which derives from the words poly, meaning many, and clones (""Klon""=Greek for sprout or twig); a clone is a group of cells arising from a common ""mother"" cell. The antibodies thus produced in a polyclonal response are known as polyclonal antibodies. The heterogeneous polyclonal antibodies are distinct from monoclonal antibody molecules, which are identical and react against a single epitope only, i.e., are more specific.Although the polyclonal response confers advantages on the immune system, in particular, greater probability of reacting against pathogens, it also increases chances of developing certain autoimmune diseases resulting from the reaction of the immune system against native molecules produced within the host.