Immune Practice Test
... kill infected cells. b) kill pathogen. c) stop the pathogen from spreading. d) create immune memory. e) create antibodies a) ...
... kill infected cells. b) kill pathogen. c) stop the pathogen from spreading. d) create immune memory. e) create antibodies a) ...
17. The Immune Response
... 3. Some attach to the invader, making the microbe less soluble and more attractive to leukocytes (Fig. 2c) Another group of WBCs, called lymphocytes, produces antibodies Antibodies are protein molecules that protect the body from invaders All cells have special markers on their cell membranes, but t ...
... 3. Some attach to the invader, making the microbe less soluble and more attractive to leukocytes (Fig. 2c) Another group of WBCs, called lymphocytes, produces antibodies Antibodies are protein molecules that protect the body from invaders All cells have special markers on their cell membranes, but t ...
9280 poster.indd
... What happens when a cell comes into contact with a surface? Cells that come into contact with a surface do so through an adsorbed layer of proteins. These proteins are present in the blood and adsorb on the surface within a matter of a few seconds. Biocompatibility is, at least in part, directed by ...
... What happens when a cell comes into contact with a surface? Cells that come into contact with a surface do so through an adsorbed layer of proteins. These proteins are present in the blood and adsorb on the surface within a matter of a few seconds. Biocompatibility is, at least in part, directed by ...
White Blood Cell Lab
... – pluripotent stem cells – most WBCs develop in the bone marrow – T lymphocytes complete development in thymus ...
... – pluripotent stem cells – most WBCs develop in the bone marrow – T lymphocytes complete development in thymus ...
Corthay cytokine talk1_final
... carcinomas and also to select for tumour cells with reduced immunogenicity. The immune response thus functions as an effective extrinsic tumour-suppressor system. However, this process also leads to the immunoselection of tumour cells that are more capable of surviving in an immunocompetent host, wh ...
... carcinomas and also to select for tumour cells with reduced immunogenicity. The immune response thus functions as an effective extrinsic tumour-suppressor system. However, this process also leads to the immunoselection of tumour cells that are more capable of surviving in an immunocompetent host, wh ...
Cell Communication
... • Play a key role in cell-cell recognition – ability of a cell to distinguish one cell from another • antigens – important in organ & tissue development – basis for rejection of foreign cells by immune system ...
... • Play a key role in cell-cell recognition – ability of a cell to distinguish one cell from another • antigens – important in organ & tissue development – basis for rejection of foreign cells by immune system ...
1. dia - immunology.unideb.hu
... cells proliferate. The surrounding stromal cells (fibroblasts) also proliferate. Both cells increase their production of TGF-β. This TGF-β acts on the surrounding stromal cells, immune cells, endothelial and smooth-muscle cells. It causes immunosuppression and angiogenesis, which makes the cancer mo ...
... cells proliferate. The surrounding stromal cells (fibroblasts) also proliferate. Both cells increase their production of TGF-β. This TGF-β acts on the surrounding stromal cells, immune cells, endothelial and smooth-muscle cells. It causes immunosuppression and angiogenesis, which makes the cancer mo ...
20150923_koyasu
... RIKEN Center for Integrative Medical Sciences, Keio University School of Medicine ...
... RIKEN Center for Integrative Medical Sciences, Keio University School of Medicine ...
Organs of the Immune System 01/31/06
... Collects fluid from tissues Major cell is lymphocyte Unidirectional Often first place where antigens are detected ...
... Collects fluid from tissues Major cell is lymphocyte Unidirectional Often first place where antigens are detected ...
Lymphatic System
... to cell contact. May also be cells involved in the aging process – may be involved in apoptosis (programmed cell death). ...
... to cell contact. May also be cells involved in the aging process – may be involved in apoptosis (programmed cell death). ...
Slide 1
... • Class II molecules “present” peptides from molecules that are taken up from outside the cell via processes such as phagocytosis (known as exogenous processing pathway) • Together the peptide and MHC form a shape (3-D structure) that may match (complement) the surface of a T cell receptor • MHC cla ...
... • Class II molecules “present” peptides from molecules that are taken up from outside the cell via processes such as phagocytosis (known as exogenous processing pathway) • Together the peptide and MHC form a shape (3-D structure) that may match (complement) the surface of a T cell receptor • MHC cla ...
Immunology: Specific Immunity
... immunoglobulins (Ig), a subclass of globulins. • Y-shaped molecule with hinges – Ends include variable regions where antigen binding occurs. – Antibodies made by a single B cell are all the same, differ from those made by another in variable region. ...
... immunoglobulins (Ig), a subclass of globulins. • Y-shaped molecule with hinges – Ends include variable regions where antigen binding occurs. – Antibodies made by a single B cell are all the same, differ from those made by another in variable region. ...
Stress and the Immune Response
... Hormone secretion increased in response to stress: Adrenaline, vasopressin, epinephrine, growth hormone, and prolactin ...
... Hormone secretion increased in response to stress: Adrenaline, vasopressin, epinephrine, growth hormone, and prolactin ...
A Timeline of Pioneering Cancer Treatment
... used in WWII chemical warfare, were found to be useful as chemotherapeutic agents against cancer. ...
... used in WWII chemical warfare, were found to be useful as chemotherapeutic agents against cancer. ...
Natural Killer Cells
... Decline in the production of new cells from the bone marrow Decline in the number of cells exported by the thymus gland Decline in responsiveness to vaccines Reduction in formation and reactivity of germinal center nodules in lymph nodes where B-cells proliferate Decreased immune surveillance by T l ...
... Decline in the production of new cells from the bone marrow Decline in the number of cells exported by the thymus gland Decline in responsiveness to vaccines Reduction in formation and reactivity of germinal center nodules in lymph nodes where B-cells proliferate Decreased immune surveillance by T l ...
Slide 1
... IgM - makes up 10% of our total antibodies. This is the predominant early antibody; the one that first activates in an initial attack of antigen. Because of its high number of antigen binding sites (5), it is an effective agglutinator of antigen . This is important in the initial activation of B-cel ...
... IgM - makes up 10% of our total antibodies. This is the predominant early antibody; the one that first activates in an initial attack of antigen. Because of its high number of antigen binding sites (5), it is an effective agglutinator of antigen . This is important in the initial activation of B-cel ...
View Syllabus
... The course explores the molecular and cellular basis of the immune response with an emphasis on immune responses to infectious disease agents and cancer and diseases resulting from dysregulation of the imm ...
... The course explores the molecular and cellular basis of the immune response with an emphasis on immune responses to infectious disease agents and cancer and diseases resulting from dysregulation of the imm ...
Immunology Introductory course Series of lectures outlining
... • Neutrophils - live ~ 1 day, migrate into tissues • Lymphocytes - majority short lived - some live for years - constantly circulate ...
... • Neutrophils - live ~ 1 day, migrate into tissues • Lymphocytes - majority short lived - some live for years - constantly circulate ...
Prezentace aplikace PowerPoint
... Bases of tumor immunity • The reaction of immunity is based on reaction to foreign antigen • Tumor must be recognised as foreign – endogennous antigen on the surface of self cells MHC I – Ts, Tc, NK • Alteration of cell antigens during tumorgenesis (lack of MHC I – desactivation of KIR, new antgien ...
... Bases of tumor immunity • The reaction of immunity is based on reaction to foreign antigen • Tumor must be recognised as foreign – endogennous antigen on the surface of self cells MHC I – Ts, Tc, NK • Alteration of cell antigens during tumorgenesis (lack of MHC I – desactivation of KIR, new antgien ...
Steps of Phagocytosis
... fragments of an antigen bind to MHC molecules on the surface of phagocyting cell = antigen presenting cell (APC) APC presents the antigens fragments to T cells T cells help B cells to produce specific antibodies, activate specific cytotoxic T cells cooperation between innate and adaptive immunity ...
... fragments of an antigen bind to MHC molecules on the surface of phagocyting cell = antigen presenting cell (APC) APC presents the antigens fragments to T cells T cells help B cells to produce specific antibodies, activate specific cytotoxic T cells cooperation between innate and adaptive immunity ...
File
... seconds of contact with the antigen. The response is caused by the release of histamine by cells which brings about the allergic symptoms. Anaphylactic shock – an immediate allergic response that occurs because the allergen has entered the blood stream. Characterized by a sudden and life ...
... seconds of contact with the antigen. The response is caused by the release of histamine by cells which brings about the allergic symptoms. Anaphylactic shock – an immediate allergic response that occurs because the allergen has entered the blood stream. Characterized by a sudden and life ...
Teacher Immunology Project
... to the immune system for evaluation Appropriate Helper T cell binds with the APC's MHCII/Antigen This activates a Helper T cell which then finds a B-cell expressing the same surface protein. When the activated Helper T cell binds to the B cell it releases Interleukin II (IL-II) which activates B cel ...
... to the immune system for evaluation Appropriate Helper T cell binds with the APC's MHCII/Antigen This activates a Helper T cell which then finds a B-cell expressing the same surface protein. When the activated Helper T cell binds to the B cell it releases Interleukin II (IL-II) which activates B cel ...
Cancer immunotherapy
Cancer immunotherapy (immuno-oncology) is the use of the immune system to treat cancer. Immunotherapies fall into three main groups: cellular, antibody and cytokine. They exploit the fact that cancer cells often have subtly different molecules on their surface that can be detected by the immune system. These molecules, known as cancer antigens, are most commonly proteins, but also include molecules such as carbohydrates. Immunotherapy is used to provoke the immune system into attacking the tumor cells by using these antigens as targets.Antibody therapies are the most successful immunotherapy, treating a wide range of cancers. Antibodies are proteins produced by the immune system that bind to a target antigen on the cell surface. In normal physiology the immune system uses them to fight pathogens. Each antibody is specific to one or a few proteins. Those that bind to cancer antigens are used to treat cancer. Cell surface receptors are common targets for antibody therapies and include the CD20, CD274, and CD279. Once bound to a cancer antigen, antibodies can induce antibody-dependent cell-mediated cytotoxicity, activate the complement system, or prevent a receptor from interacting with its ligand, all of which can lead to cell death. Multiple antibodies are approved to treat cancer, including Alemtuzumab, Ipilimumab, Nivolumab, Ofatumumab, and Rituximab.Cellular therapies, also known as cancer vaccines, usually involve the removal of immune cells from the blood or from a tumor. Immune cells specific for the tumor are activated, cultured and returned to the patient where the immune cells attack the cancer. Cell types that can be used in this way are natural killer cells, lymphokine-activated killer cells, cytotoxic T cells and dendritic cells. The only cell-based therapy approved in the US is Dendreon's Provenge, for the treatment of prostate cancer.Interleukin-2 and interferon-α are examples of cytokines, proteins that regulate and coordinate the behaviour of the immune system. They have the ability to enhance anti-tumor activity and thus can be used as cancer treatments. Interferon-α is used in the treatment of hairy-cell leukaemia, AIDS-related Kaposi's sarcoma, follicular lymphoma, chronic myeloid leukaemia and malignant melanoma. Interleukin-2 is used in the treatment of malignant melanoma and renal cell carcinoma.