10434_2012_2519_MOESM1_ESM
... found to be effective. TRCN0000072243 (shLuc) was served as control. The shRNA clones have been inserted into the pLK0.1 vector, downstream of the U6 promoter. Heh-7 and Hep-3B cells at density of 3 x 106 were transfected with 2 μg shRNA plasmids in 8 μL PolyJet™ DNA In Vitro Tranfection Reagent (Si ...
... found to be effective. TRCN0000072243 (shLuc) was served as control. The shRNA clones have been inserted into the pLK0.1 vector, downstream of the U6 promoter. Heh-7 and Hep-3B cells at density of 3 x 106 were transfected with 2 μg shRNA plasmids in 8 μL PolyJet™ DNA In Vitro Tranfection Reagent (Si ...
Chapter 14a
... Etiology of Infectious Diseases • Robert Koch demonstrated that specific microbes caused specific diseases – experimented with grazing animals infected with anthrax – Later work with TB got more interest ...
... Etiology of Infectious Diseases • Robert Koch demonstrated that specific microbes caused specific diseases – experimented with grazing animals infected with anthrax – Later work with TB got more interest ...
m1/98 summative mcq
... Pyramidal cells of cerebral cortex Is formed by layers 1 – 4 Contain both apical and basal dendrites Dendrites are studded with numerous spines Project to other parts of the cerebral cortex Project to subcortical sites ...
... Pyramidal cells of cerebral cortex Is formed by layers 1 – 4 Contain both apical and basal dendrites Dendrites are studded with numerous spines Project to other parts of the cerebral cortex Project to subcortical sites ...
click - Uplift Education
... 20. In the activation of TH, TC , and B lymphocytes, the ______________________ is physical contact between the naïve lymphocyte and an antigen presenting cell. The _______________________ can be cytokines (such as IL-2 or IL-4) or may be interaction with a TH. 21. When B lymphocytes are activated, ...
... 20. In the activation of TH, TC , and B lymphocytes, the ______________________ is physical contact between the naïve lymphocyte and an antigen presenting cell. The _______________________ can be cytokines (such as IL-2 or IL-4) or may be interaction with a TH. 21. When B lymphocytes are activated, ...
Slide 1
... in the promoter site of a specific gene or a group of genes. When this occurs, the gene will be transcribed. ...
... in the promoter site of a specific gene or a group of genes. When this occurs, the gene will be transcribed. ...
Document
... 1. Lysis of cells. This is the original function identified and causes hypotonic cell death by making hole. It is not effective against organisms with cell walls such as fungi and Gram positive bacteria 2. Opsonization. Macrophage and PMNs have FcRs and at least two different kinds of complement rec ...
... 1. Lysis of cells. This is the original function identified and causes hypotonic cell death by making hole. It is not effective against organisms with cell walls such as fungi and Gram positive bacteria 2. Opsonization. Macrophage and PMNs have FcRs and at least two different kinds of complement rec ...
Immunity - Yengage
... Suppressor T cells— Suppresses the activities of cytotoxic T cells and prevents it from destroying the body’s own tissue. It also suppresses helper T cells. Memory T cell— Some of the activated T cells do not enter the circulation but migrate to various lymphoid tissue, and get activated when body ...
... Suppressor T cells— Suppresses the activities of cytotoxic T cells and prevents it from destroying the body’s own tissue. It also suppresses helper T cells. Memory T cell— Some of the activated T cells do not enter the circulation but migrate to various lymphoid tissue, and get activated when body ...
A rough guide to the immune system - UK-CAB
... • T cells recognise antigens (small peptides)via the T cell receptor (TCR) which is always associated at the cell surface with CD3 11 • The monomeric B cell receptor (and, in fact, all antibodies) recognise antigens in solution – in their native (folded) state • The TCR does not recognise soluble an ...
... • T cells recognise antigens (small peptides)via the T cell receptor (TCR) which is always associated at the cell surface with CD3 11 • The monomeric B cell receptor (and, in fact, all antibodies) recognise antigens in solution – in their native (folded) state • The TCR does not recognise soluble an ...
Lecture Outline 7
... a. attack on joints and heart (valves) b. exposure to streptococcal toxin with epitope similar to body's own selfantigen 2. glomerulonephritis - reaction against basement membranes of glomeruli 3. myasthenia gravis a. immunity develops against ACH receptor proteins of neuromuscular junction b. cause ...
... a. attack on joints and heart (valves) b. exposure to streptococcal toxin with epitope similar to body's own selfantigen 2. glomerulonephritis - reaction against basement membranes of glomeruli 3. myasthenia gravis a. immunity develops against ACH receptor proteins of neuromuscular junction b. cause ...
Presentation1
... antigen presenting cells express MHCI, MHCII. • Other Squamous cortical TECs: express MHCII. From sheetlike structure contributing to cortico-‐medullary barrier between the two regions of each lobule ...
... antigen presenting cells express MHCI, MHCII. • Other Squamous cortical TECs: express MHCII. From sheetlike structure contributing to cortico-‐medullary barrier between the two regions of each lobule ...
Chapter 16
... of lymphocytes or the combining of antigens with antibodies. Allergic reactions are likely to be excessive and to cause tissue damage. 41. Distinguish between an antigen and an allergen. An antigen is a substance that stimulates cells to produce antibodies. An allergen is a foreign substance capable ...
... of lymphocytes or the combining of antigens with antibodies. Allergic reactions are likely to be excessive and to cause tissue damage. 41. Distinguish between an antigen and an allergen. An antigen is a substance that stimulates cells to produce antibodies. An allergen is a foreign substance capable ...
Type I Hypersensitivity
... own body by the same immune system that is supposed to protect us. Autoimmunity can happen in many organs and with many different mechanisms. This complex process of autoimmunity has actually been found to be involved in a variety of diseases. Type I Hypersensitivity: Immediate; in allergy, atopy, a ...
... own body by the same immune system that is supposed to protect us. Autoimmunity can happen in many organs and with many different mechanisms. This complex process of autoimmunity has actually been found to be involved in a variety of diseases. Type I Hypersensitivity: Immediate; in allergy, atopy, a ...
cell-mediated immunity.
... What is immunity? Immunity is the ability of organisms to resist infection by protecting themselves against disease-causing microorganisms that invade their bodies. It involves the recognition of foreign material (antigens). ...
... What is immunity? Immunity is the ability of organisms to resist infection by protecting themselves against disease-causing microorganisms that invade their bodies. It involves the recognition of foreign material (antigens). ...
15 - PLOS
... include two thresholds for binding: “strong” binders – which have a IC50 < 50nM, and “weak” binders – which have a IC50 < 500nM. However, because of the many factors that contribute to the immunodominance of an epitope and the complexity of selection pressures (which are not all immune-derived), the ...
... include two thresholds for binding: “strong” binders – which have a IC50 < 50nM, and “weak” binders – which have a IC50 < 500nM. However, because of the many factors that contribute to the immunodominance of an epitope and the complexity of selection pressures (which are not all immune-derived), the ...
Non-Specific Host Defense Lecture
... The most active phagocytes in the blood are neutrophils and monocytes. Monocytes give rise to macrophages (through diapedesis, Chap 14) that migrate to various body tissues. Phagocytic cells associated with the linings of blood vessels in the bone marrow, liver, spleen, and lymph nodes constitute th ...
... The most active phagocytes in the blood are neutrophils and monocytes. Monocytes give rise to macrophages (through diapedesis, Chap 14) that migrate to various body tissues. Phagocytic cells associated with the linings of blood vessels in the bone marrow, liver, spleen, and lymph nodes constitute th ...
Micro 532 Exam 1995
... the tuberculin test is only presumptive, indicating that he has been exposed to a tuberculosis antigen. a chest x-ray will indicate whether there has been granuloma formation due to his inability to clear the bacillus. you are looking for fluid in his lungs due to inflammation caused by the bacillus ...
... the tuberculin test is only presumptive, indicating that he has been exposed to a tuberculosis antigen. a chest x-ray will indicate whether there has been granuloma formation due to his inability to clear the bacillus. you are looking for fluid in his lungs due to inflammation caused by the bacillus ...
Skin and Mucus: Pathogens-Away!
... occurs when the person is exposed to a live pathogen, develops the disease, becomes immune as a result of the primary immune response Artificially acquired active immunity can be induced by a vaccine, a substance that contains the antigen (vaccine stimulates a primary response against the antige ...
... occurs when the person is exposed to a live pathogen, develops the disease, becomes immune as a result of the primary immune response Artificially acquired active immunity can be induced by a vaccine, a substance that contains the antigen (vaccine stimulates a primary response against the antige ...
Severe combined immune deficiency syndrome
... 7. Eight or more ear infections 8. Infections that do not resolve with antibiotic treatment for two or more months 9. Failure to gain weight or grow normally 10. Infections that require intravenous antibiotic treatment 11. Deep-seated infections, such as pneumonia that affects an entire lung or an a ...
... 7. Eight or more ear infections 8. Infections that do not resolve with antibiotic treatment for two or more months 9. Failure to gain weight or grow normally 10. Infections that require intravenous antibiotic treatment 11. Deep-seated infections, such as pneumonia that affects an entire lung or an a ...
Immune System A
... B cells become immunocompetent and selftolerant in bone marrow Some self-reactive B cells are inactivated (anergy) while others are killed Other B cells undergo receptor editing in which there is a rearrangement of their receptors ...
... B cells become immunocompetent and selftolerant in bone marrow Some self-reactive B cells are inactivated (anergy) while others are killed Other B cells undergo receptor editing in which there is a rearrangement of their receptors ...
Guillain-Barre Syndrome
... • Scavenger cells break down antigen into small peptide fragments (T cell epitopes), MHC-II epitope complexes are expressed on the surface & the scavenger become an APC which docks on a CD4 c a compatible TCR. CD4 proliferates releasing cytokines. ...
... • Scavenger cells break down antigen into small peptide fragments (T cell epitopes), MHC-II epitope complexes are expressed on the surface & the scavenger become an APC which docks on a CD4 c a compatible TCR. CD4 proliferates releasing cytokines. ...
Pathogenesis of Bacterial Infections: Host, Parasite, Environmental
... Cyanobacteria (~3.6 billion years old) earliest evidence of unicellular life Molecular phylogeny: tool that enables us to understand the complexity of life & recognize the relationships of living forms Determined by comparing difference in homologous genes encoding ribosomal RNA (16S r RNA genes fro ...
... Cyanobacteria (~3.6 billion years old) earliest evidence of unicellular life Molecular phylogeny: tool that enables us to understand the complexity of life & recognize the relationships of living forms Determined by comparing difference in homologous genes encoding ribosomal RNA (16S r RNA genes fro ...
File
... A protein produced by certain leucocytes (B lymphocytes, plasma cells) in response to a specific antigen In the bone marrow Antibodies are produced by lymphocytes once they have come into contact with a complementary/specific antigen Memory cells are a type of lymphocyte that is produced during the ...
... A protein produced by certain leucocytes (B lymphocytes, plasma cells) in response to a specific antigen In the bone marrow Antibodies are produced by lymphocytes once they have come into contact with a complementary/specific antigen Memory cells are a type of lymphocyte that is produced during the ...