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bahan kuliah eksperimentasi immunofarmakologi
bahan kuliah eksperimentasi immunofarmakologi

... – induction sites for immune responses ...
Nature of the Immune System The Immune Response
Nature of the Immune System The Immune Response

...  If the dose is too large it may cause "immune paralysis" and also fail to elicit an immune response. ...
The Immune System and Allergy
The Immune System and Allergy

... • Differ from B cell receptors only in the constant (C) region of the heavy chain • The five major types of heavy chain constant regions determine the five major classes of antibodies (M, G, A, E, and D) • Changes in the heavy chain gene that switch B cells from producing one antibody class to anoth ...
7. practice 2012
7. practice 2012

... Most cells in the immune system can be found in free or loosely adherent form. They can be easily suspensed and labeled by fluorescent antigen specific antibodies, and then they can be examined cell by cell The cells’ light scatter and immunofluorescent properties can be analyzed statistically (e.g. ...
Antibodies
Antibodies

... • Both B-cells and T-cells have antibodies on their surface. When bacteria enter the body, macrophages change the bacteria slightly and present them to the lymphocytes. The lymphocytes have antibodies that match the bacterial antigens. The Ags and Abs join. Once the B-cell is linked to an antigen, t ...
File - Science at St. Dominics
File - Science at St. Dominics

... marks it for destruction by other defence cells ...
Glossary - The Polesworth School
Glossary - The Polesworth School

... The administration of a vaccine in order to stimulate the body to develop immunity to a particular pathogen A preparation of dead or inactive pathogens injected to stimulate white blood cells to make antibodies and memory cells, so in future if infected with live pathogens of that type they will be ...
Document
Document

... 9. Assume that you had mice with mutations that diminished the function of the proteins listed below. For each, identify and explain whether lymphocyte extravasation, homing and/or immune responses would be affected. A. ICAM, a protein required for cell-to-cell adhesion ...
HSV-1
HSV-1

... A key factor involved in the intracellular edema is the keratinocytes of the middle and basal layers which are infected and undergo cytolysis, resulting in the formation of an intraepidermal lesion,which rapidly ...
Spring 2015-Chapter 16
Spring 2015-Chapter 16

... Interferon alpha and beta activate antiviral proteins in neighboring cells- they do not enter the cell they are going to protect- instead they bind to a surface receptor and trigger a G-protein activated cascade which in turn activates antiviral proteins. ...
The Human Immune System - De Soto Area School District
The Human Immune System - De Soto Area School District

... called antibody-mediated immunity, meaning that is controlled by antibodies • This represents the third line of defense in the immune system ...
antibodies - Canvas by Instructure
antibodies - Canvas by Instructure

... called antibody-mediated immunity, meaning that is controlled by antibodies • This represents the third line of defense in the immune system ...
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Infection and Defects in Defense Paula Ruedebusch

... ACQUIRED IMMUNODEFICIENCY SYNDROME (AIDS) (CONT’D) ...
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Cellular Biology

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Here

... - Your body has been exposed to the antigen in the past either through: - Exposure to the actual disease causing antigen – You fought it, you won, you remember it - Planned exposure to a form of the antigen that has been killed or weakened – You detected it, eliminated it, and remember it What is th ...
Peripheral CD4+ T cell differentiation
Peripheral CD4+ T cell differentiation

... Perturbing effector cytokines can have unintended consequences • Because of the presence of an unrecognised population of differentiated cells (e.g. Th17 cells in autoimmune disease) • Because of the importance of negative feedback circuits (e.g. the importance of IFNγ in the induction of IL-10) • ...
Microorganisms and Disease
Microorganisms and Disease

... • Gastric Juice: HCl, enzymes, mucus, acidic • Interferon: eukaryotic cells, surface receptors ...
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In This Issue - The Journal of Cell Biology

The Lymphoid System and Immunity Overview Chapter 22
The Lymphoid System and Immunity Overview Chapter 22

TATA Molecular Immunology
TATA Molecular Immunology

Study reveals that adrenergic nerves control immune cells` daily
Study reveals that adrenergic nerves control immune cells` daily

... decreased during the night, when they accumulated in lymph nodes instead. This daily, or circadian, cycle of immune cell trafficking was regulated by the neurotransmitter noradrenaline, released from adrenergic nerves innervating the lymph nodes. The nerves secreted more noradrenaline at night, acti ...
maturation
maturation

... rearranged is the Ig heavy chain In T cells, the β chain is rearranged first If rearrangement is successful, next chain can rearrange If rearrangement is not successful, cell dies by apoptosis Gene Rearrangment ...
ppt
ppt

... important in many cases. 3. Th2 cells: response to helminth parasites: - especially mast/basophil and eosinophil mediated responses (allergy) 4. NK cell response - especially early in viral and other infections - role in destruction of infected cells prior to expansion of CTL. Also important in dest ...
Thesis Abstract Drug hypersensitivity reactions represent a major
Thesis Abstract Drug hypersensitivity reactions represent a major

... clinical characteristics are very heterogeneous as drugs can elicit all types of immune reactions. The antigenicity of drugs relies on the fact that small molecules can bind covalently to carrier proteins, which become modified and then behave like a foreign antigenic proteins inducing humoral and T ...
1) The virion of the following viruses contains a polymerase EXCEPT:
1) The virion of the following viruses contains a polymerase EXCEPT:

... changing their surface antigens C The human host’s first line of defense against infections are antibodies and cytotoxic killer cells D To cause disease an infectious apthogen must be presented to the host in a way and in an environment that will allow it to grow E Virulence factors are mechanisms e ...
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Molecular mimicry

Molecular mimicry is defined as the theoretical possibility that sequence similarities between foreign and self-peptides are sufficient to result in the cross-activation of autoreactive T or B cells by pathogen-derived peptides. Despite the promiscuity of several peptide sequences which can be both foreign and self in nature, a single antibody or TCR (T cell receptor) can be activated by even a few crucial residues which stresses the importance of structural homology in the theory of molecular mimicry. Upon the activation of B or T cells, it is believed that these ""peptide mimic"" specific T or B cells can cross-react with self-epitopes, thus leading to tissue pathology (autoimmunity). Molecular mimicry is a phenomenon that has been just recently discovered as one of several ways in which autoimmunity can be evoked. A molecular mimicking event is, however, more than an epiphenomenon despite its low statistical probability of occurring and these events have serious implications in the onset of many human autoimmune disorders. In the past decade the study of autoimmunity, the failure to recognize self antigens as ""self,"" has grown immensely. Autoimmunity is a result of a loss of immunological tolerance, the ability for an individual to discriminate between self and non-self. Growth in the field of autoimmunity has resulted in more and more frequent diagnosis of autoimmune diseases. Consequently, recent data show that autoimmune diseases affect approximately 1 in 31 people within the general population. Growth has also led to a greater characterization of what autoimmunity is and how it can be studied and treated. With an increased amount of research, there has been tremendous growth in the study of the several different ways in which autoimmunity can occur, one of which is molecular mimicry. The mechanism by which pathogens have evolved, or obtained by chance, similar amino acid sequences or the homologous three-dimensional crystal structure of immunodominant epitopes remains a mystery.
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