• Study Resource
  • Explore
    • Arts & Humanities
    • Business
    • Engineering & Technology
    • Foreign Language
    • History
    • Math
    • Science
    • Social Science

    Top subcategories

    • Advanced Math
    • Algebra
    • Basic Math
    • Calculus
    • Geometry
    • Linear Algebra
    • Pre-Algebra
    • Pre-Calculus
    • Statistics And Probability
    • Trigonometry
    • other →

    Top subcategories

    • Astronomy
    • Astrophysics
    • Biology
    • Chemistry
    • Earth Science
    • Environmental Science
    • Health Science
    • Physics
    • other →

    Top subcategories

    • Anthropology
    • Law
    • Political Science
    • Psychology
    • Sociology
    • other →

    Top subcategories

    • Accounting
    • Economics
    • Finance
    • Management
    • other →

    Top subcategories

    • Aerospace Engineering
    • Bioengineering
    • Chemical Engineering
    • Civil Engineering
    • Computer Science
    • Electrical Engineering
    • Industrial Engineering
    • Mechanical Engineering
    • Web Design
    • other →

    Top subcategories

    • Architecture
    • Communications
    • English
    • Gender Studies
    • Music
    • Performing Arts
    • Philosophy
    • Religious Studies
    • Writing
    • other →

    Top subcategories

    • Ancient History
    • European History
    • US History
    • World History
    • other →

    Top subcategories

    • Croatian
    • Czech
    • Finnish
    • Greek
    • Hindi
    • Japanese
    • Korean
    • Persian
    • Swedish
    • Turkish
    • other →
 
Profile Documents Logout
Upload
Slide 1
Slide 1

... • Genetic mapping: linkage map determined by recombination frequencies – Currently have 500 markers on human genome • Physical mapping: map units • DNA sequencing: list of bases for all 3million nucleotides pairs ...
Human Genome Project
Human Genome Project

Introduction to DNA - University of Dayton
Introduction to DNA - University of Dayton

... • From your on-line computer activity, what do you know about the structure of DNA? ...
chapter 19_updates
chapter 19_updates

Arabidopsis thaliana
Arabidopsis thaliana

... 800 with best protein matches to proteins of the photosynthetic cyanobacterium Synchocystis, presumably resulting from transfer from the chloroplast to the nuclear genome. So this is another component of the large gene count. 14. There are several families of genes that are relatively hugely expande ...
Lecture
Lecture

... Function is assigned based on degree of similarity of an already characterized gene in the database 2 potential problems with this approach ...
genetic continuity
genetic continuity

... ALTER THE GENETIC INSTRUCTIONS OF AN ORGANISM BY SUBSTITUTING DNA MOLECULES ...
Pre-AP Biology 2009
Pre-AP Biology 2009

... 7. What are the three types of RNA and what are their functions? Review Figure 12-18 to note these differences. What is difference between an exon and an intron? 8. What is the purpose of transcription? What is the role of RNA in this process? ...
Binary Switches in Gene Expression: The Histone Code
Binary Switches in Gene Expression: The Histone Code

... lies outside of the DNA itself. . This system relies on packaging DNA into a DNA-histone complex called chromatin, which is the physiological substrate of all cellular processes involving the DNA. The dynamic change of the three-dimensional architecture of chromatin makes certain genes more readily ...
Genes and Mutations 1. Define: Genetics – Genetics may be defined
Genes and Mutations 1. Define: Genetics – Genetics may be defined

... Point mutation – A point mutation is one involving a change in a single nucleotide (base) within a DNA strand or in the RNA of some viruses. Point mutations may be categorized as substitutions, additions, or deletions. Translocation – A translocation (transposition) is a type of non-point mutation i ...
glossary of technical terms
glossary of technical terms

... chromosomes of almost all organisms, made up of four different kinds of bases, which are abbreviated A, C, T and G. A DNA fragment that is ten bases long might have a base sequence of, for example, ATCGTTCCTG. The particular sequence of bases encodes important information in an individual’s genetic ...
Leaving Certificate Biology Photosynthesis Quiz
Leaving Certificate Biology Photosynthesis Quiz

... Name the enzyme involved in protein synthesis which manufactures mRNA using DNA as a template. DNA polymerase ...
Cut-and-paste DNA: fixing mutations with `genome editing`
Cut-and-paste DNA: fixing mutations with `genome editing`

... The idea seemed completely impossible until recently. Cells have mechanisms that repair DNA if it’s altered, and every cell in the body has the same DNA. So the idea is much more radical than gene silencing. Recently, though, a technology called genome editing has been developed. This approach uses ...
Mutations Can Change the Meaning of Genes
Mutations Can Change the Meaning of Genes

...  Base deletions & Base insertions:  May be more harmful b/c all subsequent codons will be altered ...
Gene linkage ppt
Gene linkage ppt

... Linked genes are pairs or groups of genes which are inherited together, carried on the same chromosome (usually close together) ...
14-3: Human Molecular Genetics
14-3: Human Molecular Genetics

... Only a small part of a human DNA molecule is made up of genes. ...
13-2 Manipulating DNA
13-2 Manipulating DNA

... Chapter 13: Genetic Engineering (13-2) ...
New Microsoft Office PowerPoint Presentation
New Microsoft Office PowerPoint Presentation

Glossary of Genetic Terms
Glossary of Genetic Terms

... Deletion -- the loss of a segment of the genetic material from a chromosome. Deletion mapping -- the use of overlapping deletions to localize the position of an unknown gene on a chromosome or linkage map. Disease -- any deviation from the normal structure or function of any part, organ, or system o ...
File - Great 7th grade Scientists
File - Great 7th grade Scientists

... 2. Traits that you can see, count, or measure make up the 3. The body uses a special set of directions called 4. These dogs have different ...
Inheritance Poster 1
Inheritance Poster 1

Human Genetics and Genetic Technology Test Review Jeopardy
Human Genetics and Genetic Technology Test Review Jeopardy

... Which restriction enzyme in the chart to the left could be used to cut the DNA strand below? ...
Word Definition 1 non-Mendelian genetics rules for inheritance that
Word Definition 1 non-Mendelian genetics rules for inheritance that

... mucus in their lungs, which makes it difficult for them to breathe an international effort to sequence all 3 billion bases that make up our DNA 10 Human Genome Project and to identify within this code more than 20,000 human genes 11 genome all the DNA in one cell 12 pedigree a family tree that track ...
Simple tandem repeats in mammalian genomes
Simple tandem repeats in mammalian genomes

Mutations
Mutations

...  Inbreeding: offspring similar to parents (higher rate of genetic defects) ...
< 1 ... 429 430 431 432 433 434 435 436 437 ... 445 >

Genome editing

Genome editing, or genome editing with engineered nucleases (GEEN) is a type of genetic engineering in which DNA is inserted, replaced, or removed from a genome using artificially engineered nucleases, or ""molecular scissors."" The nucleases create specific double-stranded break (DSBs) at desired locations in the genome, and harness the cell’s endogenous mechanisms to repair the induced break by natural processes of homologous recombination (HR) and nonhomologous end-joining (NHEJ). There are currently four families of engineered nucleases being used: Zinc finger nucleases (ZFNs), Transcription Activator-Like Effector Nucleases (TALENs), the CRISPR/Cas system, and engineered meganuclease re-engineered homing endonucleases.It is commonly practiced in genetic analysis that in order to understand the function of a gene or a protein function one interferes with it in a sequence-specific way and monitors its effects on the organism. However, in some organisms it is difficult or impossible to perform site-specific mutagenesis, and therefore more indirect methods have to be used, such as silencing the gene of interest by short RNA interference (siRNA) . Yet gene disruption by siRNA can be variable and incomplete. Genome editing with nucleases such as ZFN is different from siRNA in that the engineered nuclease is able to modify DNA-binding specificity and therefore can in principle cut any targeted position in the genome, and introduce modification of the endogenous sequences for genes that are impossible to specifically target by conventional RNAi. Furthermore, the specificity of ZFNs and TALENs are enhanced as two ZFNs are required in the recognition of their portion of the target and subsequently direct to the neighboring sequences.It was chosen by Nature Methods as the 2011 Method of the Year.
  • studyres.com © 2025
  • DMCA
  • Privacy
  • Terms
  • Report