Multiomics of tomato glandular trichomes reveals
... chain (C2-C12) acyl sugars, and sesquiterpene carboxylic acids are prevalent in LC-MS-based chromatograms of LA1777 (Supplemental Figure 2). These results confirm previous metabolite analyses of tomato trichomes and underline that trichomes of these species produce different terpenoid secondary m ...
... chain (C2-C12) acyl sugars, and sesquiterpene carboxylic acids are prevalent in LC-MS-based chromatograms of LA1777 (Supplemental Figure 2). These results confirm previous metabolite analyses of tomato trichomes and underline that trichomes of these species produce different terpenoid secondary m ...
Microsoft Word
... A panel of thirteen anti-TPO mAbs produced against native human TPO, as it mentioned above, was used for the pioneering studies on the immunodominant regions located on the TPO molecule surface [5, 8]. Antibodies numbered 2, 9, 47, and 60 reacted with epitopes in domain A, mAbs 15, 18, 59, and 64 r ...
... A panel of thirteen anti-TPO mAbs produced against native human TPO, as it mentioned above, was used for the pioneering studies on the immunodominant regions located on the TPO molecule surface [5, 8]. Antibodies numbered 2, 9, 47, and 60 reacted with epitopes in domain A, mAbs 15, 18, 59, and 64 r ...
biochemical investigation into initiation of fatty acid synthesis in the
... My doctoral studies focused on studying FA metabolism in the deadly protozoan parasite T. brucei. In my dissertation, I addressed various aspects of the regulation of TbACC, which catalyzes the first committed step in FA synthesis. In the second chapter, I hypothesized that TbACC is regulated in res ...
... My doctoral studies focused on studying FA metabolism in the deadly protozoan parasite T. brucei. In my dissertation, I addressed various aspects of the regulation of TbACC, which catalyzes the first committed step in FA synthesis. In the second chapter, I hypothesized that TbACC is regulated in res ...
Biochemistry2 2016 Lecture Glycogen Metabolism
... Auto-inhibited kinases have either an N or C terminal pseudo-substrate sequence. It make the active site inaccessible to substrate. The CaM subunit binds near the auto-inhibitory sequence and the activation of CaM by binding Ca+2, binds to the auto-inhibitory sequence and it opens up the access to t ...
... Auto-inhibited kinases have either an N or C terminal pseudo-substrate sequence. It make the active site inaccessible to substrate. The CaM subunit binds near the auto-inhibitory sequence and the activation of CaM by binding Ca+2, binds to the auto-inhibitory sequence and it opens up the access to t ...
Research in Microbiology
... referred to as Kin99, Kin689, Kin1038, Kin1377 and Kin3851, respectively) (Table 3). Among these kinases, only Kin1377 does not contain a transmembrane segment in its N-terminal (Fig. 3). Similarly, the sporulation histidine kinase KinA, a major histidine kinase involved in sporulation of B. subtili ...
... referred to as Kin99, Kin689, Kin1038, Kin1377 and Kin3851, respectively) (Table 3). Among these kinases, only Kin1377 does not contain a transmembrane segment in its N-terminal (Fig. 3). Similarly, the sporulation histidine kinase KinA, a major histidine kinase involved in sporulation of B. subtili ...
Studies Into the Allosteric Regulation of ADP
... pattern. In mammals and yeast, glycogen synthesis requires a 'seed' of glycogenin, which is a self-glucosylating initiator protein, although no analogue of glycogen has been described in bacteria.4 Glycogen is a large (107 to 109 Da) and highly branched molecule. About every 10 to 14 residues of the ...
... pattern. In mammals and yeast, glycogen synthesis requires a 'seed' of glycogenin, which is a self-glucosylating initiator protein, although no analogue of glycogen has been described in bacteria.4 Glycogen is a large (107 to 109 Da) and highly branched molecule. About every 10 to 14 residues of the ...
The Role of Carbohydrate Response Element Binding Protein in
... We have analyzed the role of carbohydrate response element binding protein (ChREBP) in the pathogenesis of metabolic diseases [14]. ChREBP is a glucose-activated transcription factor that regulates glucose and lipid metabolism [5,14–17]. ChREBP is abundantly expressed in the liver and intestine [18– ...
... We have analyzed the role of carbohydrate response element binding protein (ChREBP) in the pathogenesis of metabolic diseases [14]. ChREBP is a glucose-activated transcription factor that regulates glucose and lipid metabolism [5,14–17]. ChREBP is abundantly expressed in the liver and intestine [18– ...
Amino Acids in Animal Nutrition
... the effectively utilised essential amino acids is required to optimise feed formulation and that this yields both practical and financial benefits. Over the last 2 decades crude protein concept has lost its overrated status which it had held since the start of nutrient evaluation. The world populati ...
... the effectively utilised essential amino acids is required to optimise feed formulation and that this yields both practical and financial benefits. Over the last 2 decades crude protein concept has lost its overrated status which it had held since the start of nutrient evaluation. The world populati ...
Structure of bacterial luciferase
... Structure of bacterial luciferaseBaldwin et the protease labile region that is nfissing from the [3 subunit. In the [~ subunit, the corresponding excursion consists o f - 3 5 residues. In the 0t subunit, amino acid residues from Phe272 to Thr288 were not seen in the electron density map [3°'], cons ...
... Structure of bacterial luciferaseBaldwin et the protease labile region that is nfissing from the [3 subunit. In the [~ subunit, the corresponding excursion consists o f - 3 5 residues. In the 0t subunit, amino acid residues from Phe272 to Thr288 were not seen in the electron density map [3°'], cons ...
Marine Biotecnology
... Some biochemical characteristics are similar to those found in mammalian digestive lipases: molecular masses of ∼40–50 kDa with an alkaline pI between 6.8 and 7.8 (Moreau et al. 1992; Miled et al. 2000). In crustaceans, lipases are liberated by B cells of the midgut gland (Loizzi and Peterson 1971) ...
... Some biochemical characteristics are similar to those found in mammalian digestive lipases: molecular masses of ∼40–50 kDa with an alkaline pI between 6.8 and 7.8 (Moreau et al. 1992; Miled et al. 2000). In crustaceans, lipases are liberated by B cells of the midgut gland (Loizzi and Peterson 1971) ...
Purification and Biochemical Characterization of Digestive Lipase in
... Some biochemical characteristics are similar to those found in mammalian digestive lipases: molecular masses of ∼40–50 kDa with an alkaline pI between 6.8 and 7.8 (Moreau et al. 1992; Miled et al. 2000). In crustaceans, lipases are liberated by B cells of the midgut gland (Loizzi and Peterson 1971) ...
... Some biochemical characteristics are similar to those found in mammalian digestive lipases: molecular masses of ∼40–50 kDa with an alkaline pI between 6.8 and 7.8 (Moreau et al. 1992; Miled et al. 2000). In crustaceans, lipases are liberated by B cells of the midgut gland (Loizzi and Peterson 1971) ...
AMP-activated protein kinase and metabolic control - HAL
... risk of developing this disease by >20-fold (Willett et al. 1999). Although these conditions clearly have a genetic component, as indicated by the high prevalence in certain ethnic group, the rapid increase in the prevalence of these conditions in populations throughout the world suggests the contri ...
... risk of developing this disease by >20-fold (Willett et al. 1999). Although these conditions clearly have a genetic component, as indicated by the high prevalence in certain ethnic group, the rapid increase in the prevalence of these conditions in populations throughout the world suggests the contri ...
Specific and ubiquitous expression of different Zn finger protein
... Many eucaryotic genes involved in the process of differentiation and development are expressed in a temporally and spatially restricted fashion(15). Considering that • regulation of such genes also occur at the transcriptional level,the identification of different transcriptional regulatory factors ...
... Many eucaryotic genes involved in the process of differentiation and development are expressed in a temporally and spatially restricted fashion(15). Considering that • regulation of such genes also occur at the transcriptional level,the identification of different transcriptional regulatory factors ...
SURVEY AND SUMMARY A profusion of upstream open reading
... translation of the ORF would occlude its start codon thereby preventing loading of the 43S preinitiation complex of ribosome small subunit and initiation factors onto the mRNA. Interestingly, ribosomes translating the uORF stall just before termination, in response to specific features of the nascent ...
... translation of the ORF would occlude its start codon thereby preventing loading of the 43S preinitiation complex of ribosome small subunit and initiation factors onto the mRNA. Interestingly, ribosomes translating the uORF stall just before termination, in response to specific features of the nascent ...
CHRYSAORA QUINQUECIRRHA) Research Article
... encephalopathy (BSE) and the foot-and-mouth disease (FMD), the main sources of collagen in many fields are limited to those of bovine or porcine dermis, so more and more studies turn to find safe sources of collagen. There have been many reports of collagen in aquatic animals. Collagen possesses a m ...
... encephalopathy (BSE) and the foot-and-mouth disease (FMD), the main sources of collagen in many fields are limited to those of bovine or porcine dermis, so more and more studies turn to find safe sources of collagen. There have been many reports of collagen in aquatic animals. Collagen possesses a m ...
Exploring the directionality of Escherichia coli formate
... deserves further investigation, not least as the harnessing of an alternative biological reaction capable of synthesizing organic acid from CO2 may have several biotechnological applications. In this work, experimental evidence is provided that demonstrate E. coli FHL is reversible in vivo and also ...
... deserves further investigation, not least as the harnessing of an alternative biological reaction capable of synthesizing organic acid from CO2 may have several biotechnological applications. In this work, experimental evidence is provided that demonstrate E. coli FHL is reversible in vivo and also ...
Spring 2005 - AT Children`s Project
... A-T Children’s Project, are working together to make another rodent model of A-T using the rat, which may possess neurological abnormalities similar to those seen in patients. For years mice have been genetically manipulated in order to gain a better understanding of human disease. For example, rese ...
... A-T Children’s Project, are working together to make another rodent model of A-T using the rat, which may possess neurological abnormalities similar to those seen in patients. For years mice have been genetically manipulated in order to gain a better understanding of human disease. For example, rese ...
- Wiley Online Library
... which is provided by nitrate reduction or by ammonia oxidation in biological habitats (Fig. 1). Reduction of nitrite can be regarded as an assimilatory, respiratory or dissimilatory process [1]. Assimilatory nitrite reduction serves in the production of ammonia which is incorporated into cell materi ...
... which is provided by nitrate reduction or by ammonia oxidation in biological habitats (Fig. 1). Reduction of nitrite can be regarded as an assimilatory, respiratory or dissimilatory process [1]. Assimilatory nitrite reduction serves in the production of ammonia which is incorporated into cell materi ...
ppt for
... 2) Olfactory receptors and miRNAs are lost at the same rate with which they are acquired. However, not a single cluster loss was observed for piRNA. ...
... 2) Olfactory receptors and miRNAs are lost at the same rate with which they are acquired. However, not a single cluster loss was observed for piRNA. ...
Introduction to Nutrition and Metabolism, Third Edition
... The food we eat has a major effect on our physical health and psychological wellbeing. An understanding of the way in which nutrients are metabolized, and hence of the principles of biochemistry, is essential for an understanding of the scientific basis of what we would call a prudent or healthy die ...
... The food we eat has a major effect on our physical health and psychological wellbeing. An understanding of the way in which nutrients are metabolized, and hence of the principles of biochemistry, is essential for an understanding of the scientific basis of what we would call a prudent or healthy die ...
Major players on the microbial stage: why archaea
... used to determine the presence of archaea in environments even when the organisms themselves remained unculturable. In addition to ssrRNA signatures, evidence for an archaeal ‘genomic signature’ has been presented. The archaeal genomic signature presented by Graham et al. (2000) is a set of over 350 ...
... used to determine the presence of archaea in environments even when the organisms themselves remained unculturable. In addition to ssrRNA signatures, evidence for an archaeal ‘genomic signature’ has been presented. The archaeal genomic signature presented by Graham et al. (2000) is a set of over 350 ...
Doctorial Thesis Regulation of Branched
... dichloroacetate (Harris et al., 2001). In contrast, a change in gene expression to alter the concentration of BDK involves nutrient status or hormones such as thyroid ...
... dichloroacetate (Harris et al., 2001). In contrast, a change in gene expression to alter the concentration of BDK involves nutrient status or hormones such as thyroid ...
Structure of a Pheromone Receptor-Associated MHC Molecule with
... thermally unstable, suggesting that its groove is normally occupied. However, M10.5 does not bind endogenous peptides when expressed in mammalian cells or when offered a mixture of class I–binding peptides. The F pocket side of the M10.5 groove is open, suggesting that ligands larger than 8–10-mer c ...
... thermally unstable, suggesting that its groove is normally occupied. However, M10.5 does not bind endogenous peptides when expressed in mammalian cells or when offered a mixture of class I–binding peptides. The F pocket side of the M10.5 groove is open, suggesting that ligands larger than 8–10-mer c ...
Mitochondria - Physical Mathematics
... most striking features of both mitochondria and chloroplasts are their extensive internal membrane systems. These internal membranes contain sets of membrane protein complexes that work together to produce most of the cell’s ATP. In bacteria, simpler versions of essentially the same protein complexe ...
... most striking features of both mitochondria and chloroplasts are their extensive internal membrane systems. These internal membranes contain sets of membrane protein complexes that work together to produce most of the cell’s ATP. In bacteria, simpler versions of essentially the same protein complexe ...
Two-hybrid screening
Two-hybrid screening (also known as yeast two-hybrid system or Y2H) is a molecular biology technique used to discover protein–protein interactions (PPIs) and protein–DNA interactions by testing for physical interactions (such as binding) between two proteins or a single protein and a DNA molecule, respectively.The premise behind the test is the activation of downstream reporter gene(s) by the binding of a transcription factor onto an upstream activating sequence (UAS). For two-hybrid screening, the transcription factor is split into two separate fragments, called the binding domain (BD) and activating domain (AD). The BD is the domain responsible for binding to the UAS and the AD is the domain responsible for the activation of transcription. The Y2H is thus a protein-fragment complementation assay.