Recycling of vitamin B12 and NAD+ within the Pdu
... dehydrogenase PduP that respectively use AdoCbl and NAD+ as cofactors, are encapsulated within the solid protein shell of the MCP. During catalysis, the adenosyl-group of AdoCbl bound to PduCDE is periodically lost due to by-reactions and is usually replaced by a hydroxo-group resulting in the forma ...
... dehydrogenase PduP that respectively use AdoCbl and NAD+ as cofactors, are encapsulated within the solid protein shell of the MCP. During catalysis, the adenosyl-group of AdoCbl bound to PduCDE is periodically lost due to by-reactions and is usually replaced by a hydroxo-group resulting in the forma ...
Lab 5 Sugar Fermentation in Yeast
... energy stored in ATP can then be used to perform cellular work: provide energy for biosynthetic reactions (e.g. growth and repair processes, active transport, etc.). All organisms (i.e. monerans, protists, fungi, plants, and animals) utilize aerobic respiration and/or fermentation (anaerobic respira ...
... energy stored in ATP can then be used to perform cellular work: provide energy for biosynthetic reactions (e.g. growth and repair processes, active transport, etc.). All organisms (i.e. monerans, protists, fungi, plants, and animals) utilize aerobic respiration and/or fermentation (anaerobic respira ...
Gene Section SOX10 (SRY (sex determining region Y)-box 10)
... different sets of transcription factors. SOX10 probably shares further roles with its close relatives SOX9 and SOX8 with which it is co-expressed in several cell types and functions in a partly redundant manner. ...
... different sets of transcription factors. SOX10 probably shares further roles with its close relatives SOX9 and SOX8 with which it is co-expressed in several cell types and functions in a partly redundant manner. ...
The Nucleotide Sequence of a Type 3 Poliovirus Isolated During a
... the representatives of each of the three poliovirus serotypes sequenced to date. These are the type 1 strain P1/Mahoney (Kitamura et al., 1981) and type 3 strain P3/Leon/37 (Stanway et al., 1984b), which are wild-type strains, and the Sabin type 2 vaccine strain P2/P712, Ch, 2ab (Toyoda et al., 1984 ...
... the representatives of each of the three poliovirus serotypes sequenced to date. These are the type 1 strain P1/Mahoney (Kitamura et al., 1981) and type 3 strain P3/Leon/37 (Stanway et al., 1984b), which are wild-type strains, and the Sabin type 2 vaccine strain P2/P712, Ch, 2ab (Toyoda et al., 1984 ...
The Nucleotide Sequence of a Type 3 Poliovirus Isolated During a
... the representatives of each of the three poliovirus serotypes sequenced to date. These are the type 1 strain P1/Mahoney (Kitamura et al., 1981) and type 3 strain P3/Leon/37 (Stanway et al., 1984b), which are wild-type strains, and the Sabin type 2 vaccine strain P2/P712, Ch, 2ab (Toyoda et al., 1984 ...
... the representatives of each of the three poliovirus serotypes sequenced to date. These are the type 1 strain P1/Mahoney (Kitamura et al., 1981) and type 3 strain P3/Leon/37 (Stanway et al., 1984b), which are wild-type strains, and the Sabin type 2 vaccine strain P2/P712, Ch, 2ab (Toyoda et al., 1984 ...
Distribution bias analysis of germline and somatic single
... our analysis above, we highlight 132 key pfsSNVs within 17 genes that are found in well-established cancer associated gene lists. For illustrating how key pfsSNVs can be prioritized further, we provide a use case where we performed survival analysis showing that a loss of phosphorylation site pfsSNV ...
... our analysis above, we highlight 132 key pfsSNVs within 17 genes that are found in well-established cancer associated gene lists. For illustrating how key pfsSNVs can be prioritized further, we provide a use case where we performed survival analysis showing that a loss of phosphorylation site pfsSNV ...
Expression of phosphofructokinase in Neisseria meningitidis
... during the evolution of the species this activity was lost (Bapteste et al., 2003), the question of why N. meningitidis lost PFK activity remains. In particular, since glucose is present within nasopharyngeal tissue (Exley et al., 2005), the presence of PFK can yield one additional ATP per unit of s ...
... during the evolution of the species this activity was lost (Bapteste et al., 2003), the question of why N. meningitidis lost PFK activity remains. In particular, since glucose is present within nasopharyngeal tissue (Exley et al., 2005), the presence of PFK can yield one additional ATP per unit of s ...
pH-induced conformational changes in human ABO(H) blood group
... state in which the C-terminal loop is ordered is strongly affected by contact from the C-terminal loop to the L-fucose residue of the H-antigen acceptor (Alfaro et al. 2008). Accordingly, with the exception of GTA, which has recently been shown to form the closed state most readily even in the absen ...
... state in which the C-terminal loop is ordered is strongly affected by contact from the C-terminal loop to the L-fucose residue of the H-antigen acceptor (Alfaro et al. 2008). Accordingly, with the exception of GTA, which has recently been shown to form the closed state most readily even in the absen ...
Are You suprised ?
... organisms that appear to have few physical similarities may have similar sequences of amino acids in their proteins and be closely related through evolution. Many researchers believe that the greater the similarity in the amino-acid sequences of two organisms, the more closely related they are in an ...
... organisms that appear to have few physical similarities may have similar sequences of amino acids in their proteins and be closely related through evolution. Many researchers believe that the greater the similarity in the amino-acid sequences of two organisms, the more closely related they are in an ...
Cra-mediated regulation of Escherichia coli adenylate cyclase
... of many genes (Saier & Ramseier, 1996). cAMP is also essential for transcriptional regulation of many genes via its receptor protein CRP. When complexed with CAMP, CRP binds to specific sites upstream of promoters, causing transcriptional activation or repression (Kolb et al., 1993). A CRP binding s ...
... of many genes (Saier & Ramseier, 1996). cAMP is also essential for transcriptional regulation of many genes via its receptor protein CRP. When complexed with CAMP, CRP binds to specific sites upstream of promoters, causing transcriptional activation or repression (Kolb et al., 1993). A CRP binding s ...
In Vitro Characterization of Human Growth Hormone
... I would like to thank Prof. Dr. Joseph Köhrle for accepting me to the DFG-funded graduate college 1208, which allowed me to take part in its versatile curriculum. I would like to thank the fellow students for peer support and many unforgettable moments. A special thank you goes to the following grou ...
... I would like to thank Prof. Dr. Joseph Köhrle for accepting me to the DFG-funded graduate college 1208, which allowed me to take part in its versatile curriculum. I would like to thank the fellow students for peer support and many unforgettable moments. A special thank you goes to the following grou ...
Temperature, pressure, and electrochemical
... shown in Fig. 1c, seven are ionizable at pHs of 0 to 14. Because of the availability of experimental data for amino acids, we have used them as the primary model compounds for the sidechain groups. The amino acid backbone group, denoted by [AABB], is a zwitterionic structure that itself contains two ...
... shown in Fig. 1c, seven are ionizable at pHs of 0 to 14. Because of the availability of experimental data for amino acids, we have used them as the primary model compounds for the sidechain groups. The amino acid backbone group, denoted by [AABB], is a zwitterionic structure that itself contains two ...
Structure, function, and evolution of phosphoglycerate mutases
... (Campbell et al., 1974; Ridgen et al., 1998). However, every monomer is built from two domains with the larger domain having a nucleotide-binding fold that was thought not to have any physiological relevance (Campbell et al., 1974; Winn et al., 1981). However, charged ligands other than nucleotides, ...
... (Campbell et al., 1974; Ridgen et al., 1998). However, every monomer is built from two domains with the larger domain having a nucleotide-binding fold that was thought not to have any physiological relevance (Campbell et al., 1974; Winn et al., 1981). However, charged ligands other than nucleotides, ...
Arctigenin Efficiently Enhanced Sedentary Mice Treadmill
... energy homeostasis, and its activation could improve glucose uptake, promote mitochondrial biogenesis and increase glycolysis. Recent research has even suggested that AMPK activation contributed to endurance enhancement without exercise. Here we report that the natural product arctigenin from the tr ...
... energy homeostasis, and its activation could improve glucose uptake, promote mitochondrial biogenesis and increase glycolysis. Recent research has even suggested that AMPK activation contributed to endurance enhancement without exercise. Here we report that the natural product arctigenin from the tr ...
General principles of cellular organization in the genome
... metabolic network of 129 enzymes catalyzing 189 reactions was constructed. This metabolic map allowed the design of a defined, minimal medium with 19 essential nutrients. In summary, the M. pneumoniae metabolic network has a more linear topology and contains a higher fraction of multifunctional enzy ...
... metabolic network of 129 enzymes catalyzing 189 reactions was constructed. This metabolic map allowed the design of a defined, minimal medium with 19 essential nutrients. In summary, the M. pneumoniae metabolic network has a more linear topology and contains a higher fraction of multifunctional enzy ...
and Rhizobiales-Like PPP-Family Protein Phosphatases from
... identified PPP-family protein phosphatase subclasses from the model photosynthetic Eukaryote Arabidopsis thaliana. These two subclasses included the Shewanella-like (SLP1 and 2) and Rhizobiales-like (RLPH2) phosphatases, which were named after their relatedness to phosphatase orthologs from Shewanel ...
... identified PPP-family protein phosphatase subclasses from the model photosynthetic Eukaryote Arabidopsis thaliana. These two subclasses included the Shewanella-like (SLP1 and 2) and Rhizobiales-like (RLPH2) phosphatases, which were named after their relatedness to phosphatase orthologs from Shewanel ...
video slide - Point Pleasant Beach School District
... Another side note… Drawing organic moleculesSometimes the drawings showing monosaccharides are simplified to show only the most important parts of the molecules. The same sequence of events diagrammed above could be shown as: Here the hydrogens that complete each molecule are simply 'understood' to ...
... Another side note… Drawing organic moleculesSometimes the drawings showing monosaccharides are simplified to show only the most important parts of the molecules. The same sequence of events diagrammed above could be shown as: Here the hydrogens that complete each molecule are simply 'understood' to ...
5 The structure and function of membrane proteins
... biochemistry arising from the pioneering work of Pauling, Sumner, Kendrew, Perutz, Anfinsen, together with other scientific ‘giants’ too numerous to describe at length in this text. The area seemed complete. How wrong I was and how wrong an undergraduate’s perception can be! The last 30 years have see ...
... biochemistry arising from the pioneering work of Pauling, Sumner, Kendrew, Perutz, Anfinsen, together with other scientific ‘giants’ too numerous to describe at length in this text. The area seemed complete. How wrong I was and how wrong an undergraduate’s perception can be! The last 30 years have see ...
Identification of the Gene Encoding the Tryptophan Synthase ß
... diploid strains of a given genotype were examined. For the same reason, potential diploid strains were kept under selective conditions until transfer onto other diagnostic media. The effectiveness of the diploid-strain-selection technique was confirmed by DNA hybridization using the mating-type-spec ...
... diploid strains of a given genotype were examined. For the same reason, potential diploid strains were kept under selective conditions until transfer onto other diagnostic media. The effectiveness of the diploid-strain-selection technique was confirmed by DNA hybridization using the mating-type-spec ...
- Free Documents
... The molecular switches Iall into two main classes that operate in diIIerent ways, although in both cases it is the gain or loss oI phosphate groups that determines whether the protein is active or inactive. The largest class consists oI proteins that are activated or inactivated by . For these prote ...
... The molecular switches Iall into two main classes that operate in diIIerent ways, although in both cases it is the gain or loss oI phosphate groups that determines whether the protein is active or inactive. The largest class consists oI proteins that are activated or inactivated by . For these prote ...
Collagen XV: Exploring Its Structure and Role within the Tumor
... as endostatin, unlike restin, has been implicated as an antiangiogenic polypeptide fragment (17, 19). Moreover, in experiments to test the hypothesis that collagen XV is a dose-dependent suppressor of tumorigenicity, the restin domain alone was shown not to be involved, whereas the N-terminal portio ...
... as endostatin, unlike restin, has been implicated as an antiangiogenic polypeptide fragment (17, 19). Moreover, in experiments to test the hypothesis that collagen XV is a dose-dependent suppressor of tumorigenicity, the restin domain alone was shown not to be involved, whereas the N-terminal portio ...
Two-hybrid screening
Two-hybrid screening (also known as yeast two-hybrid system or Y2H) is a molecular biology technique used to discover protein–protein interactions (PPIs) and protein–DNA interactions by testing for physical interactions (such as binding) between two proteins or a single protein and a DNA molecule, respectively.The premise behind the test is the activation of downstream reporter gene(s) by the binding of a transcription factor onto an upstream activating sequence (UAS). For two-hybrid screening, the transcription factor is split into two separate fragments, called the binding domain (BD) and activating domain (AD). The BD is the domain responsible for binding to the UAS and the AD is the domain responsible for the activation of transcription. The Y2H is thus a protein-fragment complementation assay.