Molecular Genetic Analysis of Phototropism in
... phototropin1 (phot1) and phototropin2 (phot2), with corresponding gene name changes (Briggs et al. 2001). Blue light irradiation activates the kinase activity of the phototropins (reviewed by Christie 2007). Each FMN molecule associates with the LOV domains non-covalently in a dark state. Blue light ...
... phototropin1 (phot1) and phototropin2 (phot2), with corresponding gene name changes (Briggs et al. 2001). Blue light irradiation activates the kinase activity of the phototropins (reviewed by Christie 2007). Each FMN molecule associates with the LOV domains non-covalently in a dark state. Blue light ...
The contribution of the Trp/Met/Phe residues to physical interactions
... domain to CBP C-terminus promotes acetylation of the p53 Cterminal lysine residues by CBP/p300. The acetylations of the lysine residues contribute to the p53 stabilization by disabling the lysines as the ubiquitylation targets. The acetylation of p53 also stimulates its sequence specific DNA-binding ...
... domain to CBP C-terminus promotes acetylation of the p53 Cterminal lysine residues by CBP/p300. The acetylations of the lysine residues contribute to the p53 stabilization by disabling the lysines as the ubiquitylation targets. The acetylation of p53 also stimulates its sequence specific DNA-binding ...
Basic Science for Clinicians
... However, the molecular signaling role of AMP is dramatically extended by activation of the AMPK pathway. Because many more proteins are regulated by AMPK than contain specialized AMP-binding sites, the ability of AMP to signal energy compromise is greatly enhanced. AMPK is a protein kinase that has ...
... However, the molecular signaling role of AMP is dramatically extended by activation of the AMPK pathway. Because many more proteins are regulated by AMPK than contain specialized AMP-binding sites, the ability of AMP to signal energy compromise is greatly enhanced. AMPK is a protein kinase that has ...
Serine racemases from barley, Hordeum vulgare L., and other plant
... serine racemase activity was increased by divalent cations but not by ATP. This suggests that the interaction of the enzyme with ATP and the divalent cation restricts the substrate specificity of eukaryotic racemases. A novel mechanism of mammalian serine racemase has been proposed, whereby dehydrat ...
... serine racemase activity was increased by divalent cations but not by ATP. This suggests that the interaction of the enzyme with ATP and the divalent cation restricts the substrate specificity of eukaryotic racemases. A novel mechanism of mammalian serine racemase has been proposed, whereby dehydrat ...
Functional unit of RNA polymerase II
... The requirement for a minimum number of diheptads also can help to explain the results from our evolutionary complementation experiments. Based on their need for eight heptads and assuming there is some functional redundancy in overlapping pairs, yeast could require at least seven functional dihepta ...
... The requirement for a minimum number of diheptads also can help to explain the results from our evolutionary complementation experiments. Based on their need for eight heptads and assuming there is some functional redundancy in overlapping pairs, yeast could require at least seven functional dihepta ...
Evidence for Several Cysteine Transport Mechanisms in the
... mitochondria in the presence of two external concentrations of [35S]cysteine, namely 10 and 150 mM, over 3 min at 25 C was examined (Fig. 2A, B). The uptake of 10 and 150 mM radiolabeled cysteine was very rapid at a rate of 8.2 and 59.2 pmol mg 1 protein s 1, respectively, in the first 30 s (assumi ...
... mitochondria in the presence of two external concentrations of [35S]cysteine, namely 10 and 150 mM, over 3 min at 25 C was examined (Fig. 2A, B). The uptake of 10 and 150 mM radiolabeled cysteine was very rapid at a rate of 8.2 and 59.2 pmol mg 1 protein s 1, respectively, in the first 30 s (assumi ...
Universitat Autònoma de Barcelona
... Dasari M, Espargaró A, Sabaté R, Lopez del Amo JM, Fink U, Grelle G, Bieschke J, Ventura S, Reif B Chembiochem, Feb 2011;12(3):407-423 4. Deciphering the role of the thermodynamic and kinetic stabilities of SH3 domains on their aggregation inside bacteria Castillo V, Espargaró A, Gordo V, Vendrell J ...
... Dasari M, Espargaró A, Sabaté R, Lopez del Amo JM, Fink U, Grelle G, Bieschke J, Ventura S, Reif B Chembiochem, Feb 2011;12(3):407-423 4. Deciphering the role of the thermodynamic and kinetic stabilities of SH3 domains on their aggregation inside bacteria Castillo V, Espargaró A, Gordo V, Vendrell J ...
Molecular basis of hepatic carnitine palmitoyltransferase I deficiency
... mutation (Fig. 1). As a consequence of this mutation the aspartate at position 454 is changed into a glycine (D454G). The finding of the A1361G mutation in a heterozygous form in both parents (Fig. 1) indicates that the patient is truly homozygous for this mutation. Expression studies. The aspartate ...
... mutation (Fig. 1). As a consequence of this mutation the aspartate at position 454 is changed into a glycine (D454G). The finding of the A1361G mutation in a heterozygous form in both parents (Fig. 1) indicates that the patient is truly homozygous for this mutation. Expression studies. The aspartate ...
5 The structure and function of membrane proteins
... can now search databases comparing proteins at the level of DNA or amino acid sequences, building up patterns of homology and relationships that provide insight into origin and possible function. In addition we use computers routinely to calculate properties such as isoelectric point, number of hydr ...
... can now search databases comparing proteins at the level of DNA or amino acid sequences, building up patterns of homology and relationships that provide insight into origin and possible function. In addition we use computers routinely to calculate properties such as isoelectric point, number of hydr ...
General principles of cellular organization in the genome
... latter show decaying expression in a staircase-like manner. Under various conditions, operons General principles of cellular organization in Mycoplasma pneumoniae ...
... latter show decaying expression in a staircase-like manner. Under various conditions, operons General principles of cellular organization in Mycoplasma pneumoniae ...
Hydrolyzed Source Proteins as Used in Cosmetics
... All interested persons are provided 60 days from the above date to comment on this Scientific Literature Review and to identify additional published data that should be included or provide unpublished data which can be made public and included. Information may be submitted without identifying the so ...
... All interested persons are provided 60 days from the above date to comment on this Scientific Literature Review and to identify additional published data that should be included or provide unpublished data which can be made public and included. Information may be submitted without identifying the so ...
Distinct Cellular and Molecular Mechanisms Underlie Functional
... Subsequent experiments examined the impact of TACinduced LVH on the transcript and protein expression levels of several channel pore-forming (␣) and accessory () subunits encoding murine myocardial K⫹ channels.14,19,22–24 Because accumulating evidence suggests that cardiac ion channels function as ...
... Subsequent experiments examined the impact of TACinduced LVH on the transcript and protein expression levels of several channel pore-forming (␣) and accessory () subunits encoding murine myocardial K⫹ channels.14,19,22–24 Because accumulating evidence suggests that cardiac ion channels function as ...
IN VIVO ENOL CASTOR OIL SEEDS AT THREONINE-4 AND SERINE-451
... mitochondrial production of carbon skeletons and ATP needed for storage protein biosynthesis (Fig. 1.3) [17, 93]. 1.2 Carbon partitioning in developing seeds In developing seeds the partitioning of imported photosynthate between starch, storage lipid (triglycerides), and storage protein biosynthesis ...
... mitochondrial production of carbon skeletons and ATP needed for storage protein biosynthesis (Fig. 1.3) [17, 93]. 1.2 Carbon partitioning in developing seeds In developing seeds the partitioning of imported photosynthate between starch, storage lipid (triglycerides), and storage protein biosynthesis ...
The Plant Cell
... coli resistance to a group of antimicrobial agents that are similar to but not overlapping with those to which NorM confers resistance. The significant reduction in norfloxacin accumulation in E. coli cells attributed to NorM expression can be eliminated rapidly by dissipation of the proton gradient ...
... coli resistance to a group of antimicrobial agents that are similar to but not overlapping with those to which NorM confers resistance. The significant reduction in norfloxacin accumulation in E. coli cells attributed to NorM expression can be eliminated rapidly by dissipation of the proton gradient ...
The Cutting Edge of Affinity Electrophoresis Technology
... Figure 3. Saccharide affinity electrophoresis. (A) Reversible bonding between a boron compound and a polysaccharide; (B) the affinity probe MPBA. 5. Supported Molecular Matrix Electrophoresis and Its Application to Affinity Electrophoresis Mucins are viscous glycoproteins produced by epithelial cell ...
... Figure 3. Saccharide affinity electrophoresis. (A) Reversible bonding between a boron compound and a polysaccharide; (B) the affinity probe MPBA. 5. Supported Molecular Matrix Electrophoresis and Its Application to Affinity Electrophoresis Mucins are viscous glycoproteins produced by epithelial cell ...
Physiological and Transcriptomic Aspects of Urea
... port mechanisms and are mediated by probable transmembrane proteins. The molecular basis of urea transport is just beginning to be understood in Arabidopsis (Arabidopsis thaliana). The identification of the highaffinity urea transporter AtDUR3 by Liu et al. (2003a) and of the AtTIP (for tonoplast in ...
... port mechanisms and are mediated by probable transmembrane proteins. The molecular basis of urea transport is just beginning to be understood in Arabidopsis (Arabidopsis thaliana). The identification of the highaffinity urea transporter AtDUR3 by Liu et al. (2003a) and of the AtTIP (for tonoplast in ...
Pollen Exine Pattern Formation is Dependent on Three Major
... formation (Figs. 2, 3A; reviewed by Piffanelli et al. 1998). There are two major organelles in the tapetum, lipid bodies and plastids, and the lipid components are highly accumulated in these organelles (Fig. 3B). These morphological characteristics have been well examined in several plant species, ...
... formation (Figs. 2, 3A; reviewed by Piffanelli et al. 1998). There are two major organelles in the tapetum, lipid bodies and plastids, and the lipid components are highly accumulated in these organelles (Fig. 3B). These morphological characteristics have been well examined in several plant species, ...
Characterization of the Sucrose Phosphate Phosphatase (SPP
... 2.4.1.14) and sucrose-phosphate phosphatase (SPP; EC 3.1.3.24). SPS catalyses the synthesis of Suc-6-P from UDP-glucose and fructose-6-phosphate (Fru6P). In the second step of the pathway, SPP catalyses the irreversible hydrolysis of Suc-6-P to sucrose and displaces the reaction catalysed by SPS in ...
... 2.4.1.14) and sucrose-phosphate phosphatase (SPP; EC 3.1.3.24). SPS catalyses the synthesis of Suc-6-P from UDP-glucose and fructose-6-phosphate (Fru6P). In the second step of the pathway, SPP catalyses the irreversible hydrolysis of Suc-6-P to sucrose and displaces the reaction catalysed by SPS in ...
Supplementary materials - Stanford Artificial Intelligence Laboratory
... regulators in (8-10). For each deletion we defined a threshold for differentially expressed as described in (11). For the full set of annotations (function, binding data and DEG targets), we removed all annotations associated with less than five genes from our gene set. For each module and each anno ...
... regulators in (8-10). For each deletion we defined a threshold for differentially expressed as described in (11). For the full set of annotations (function, binding data and DEG targets), we removed all annotations associated with less than five genes from our gene set. For each module and each anno ...
Two nearly identical terpene synthases catalyze the
... Center, http://www.hgsc.bcm.tmc.edu). Residues in black are conserved (identical in at least four out of six sequences shown), whereas residues in gray are similar in at least two of the six sequences shown. Dashes indicate gaps inserted for optimal alignment. The horizontal line indicates the N-ter ...
... Center, http://www.hgsc.bcm.tmc.edu). Residues in black are conserved (identical in at least four out of six sequences shown), whereas residues in gray are similar in at least two of the six sequences shown. Dashes indicate gaps inserted for optimal alignment. The horizontal line indicates the N-ter ...
Desert hedgehog is a mammal-specific gene expressed during testicular and ovarian
... protein and that of mouse [43]. A short stretch of N-terminal residues (25 for the tammar and 22 for the mouse) were highly hydrophobic and presumed to function as a signalling peptide. There was a conserved 6 amino acid stretch, CGPGRG, after the signal peptide used to generate the secreted form of ...
... protein and that of mouse [43]. A short stretch of N-terminal residues (25 for the tammar and 22 for the mouse) were highly hydrophobic and presumed to function as a signalling peptide. There was a conserved 6 amino acid stretch, CGPGRG, after the signal peptide used to generate the secreted form of ...
Desert hedgehogis a mammal-specific gene expressed during
... protein and that of mouse [43]. A short stretch of N-terminal residues (25 for the tammar and 22 for the mouse) were highly hydrophobic and presumed to function as a signalling peptide. There was a conserved 6 amino acid stretch, CGPGRG, after the signal peptide used to generate the secreted form of ...
... protein and that of mouse [43]. A short stretch of N-terminal residues (25 for the tammar and 22 for the mouse) were highly hydrophobic and presumed to function as a signalling peptide. There was a conserved 6 amino acid stretch, CGPGRG, after the signal peptide used to generate the secreted form of ...
Print - Circulation
... subunit. It has recently become possible to express cardiac a, subunits in Xenopus oocytes by injecting the appropriate messenger RNA.30 By expressing the skeletal muscle subunits a2/8 and f3 alone or in combination, it has become possible to demonstrate interactions between these subunits and a. Th ...
... subunit. It has recently become possible to express cardiac a, subunits in Xenopus oocytes by injecting the appropriate messenger RNA.30 By expressing the skeletal muscle subunits a2/8 and f3 alone or in combination, it has become possible to demonstrate interactions between these subunits and a. Th ...
cerevisiae - Oxford Academic
... what we know about the residues inserted by readthrough at stop codons in eukaryotes or about the natural suppressor tRNAs involved in this process was gleaned from in vitro experiments in rabbit reticulocyte lysate (RRL) (20). For example, tryptophan, cysteine and arginine were identified at UGA st ...
... what we know about the residues inserted by readthrough at stop codons in eukaryotes or about the natural suppressor tRNAs involved in this process was gleaned from in vitro experiments in rabbit reticulocyte lysate (RRL) (20). For example, tryptophan, cysteine and arginine were identified at UGA st ...
Applications of NMR in Drug Discovery
... relaxation rates [5, 22, 24]. The spectral overlap increases with molecular weight and the structure becomes more difficult to solve. However, the size limit has increased steadily throughout the years as NMR becomes more sensitive by using higher magnetic fields, cryogenic probes, miniaturised samp ...
... relaxation rates [5, 22, 24]. The spectral overlap increases with molecular weight and the structure becomes more difficult to solve. However, the size limit has increased steadily throughout the years as NMR becomes more sensitive by using higher magnetic fields, cryogenic probes, miniaturised samp ...