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Carbon-Based Molecules
Carbon-Based Molecules

... fatty acids are shown in figure 3.4. Many lipids, both fats and oils, contain three fatty acids bonded to glycerol. They are called triglycerides. Most animal fats are saturated fats, which means they have the maximum number of hydrogen atoms possible. That is, every place that a hydrogen atom can ...
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... gradient of glucose (and other sugars) across plasma membranes and exhibit different substrate specificities, kinetic properties and tissue expression profiles. The first transporter to be isolated, GLUT1, was cloned from a HepG2 cell line (Mueckler et al. 1985). Identification of other members of t ...
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Biochemistry I, Spring Term 2000 - Third Exam

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Boosting Omega-3 Uptake with Organic Minerals

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... Energy transfer in the heart. Because the whole is greater than the sum of its parts, an understanding of the control and regulation of energy substrate metabolism remains an important field of research. Energy is the capacity to do work. The release of energy from fuels is achieved by the step-by-s ...
energy & cellular respiration
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... The long, flexible link between biotin and the enzyme enables the carboxybiotin to rotate from one active site of the enzyme (the ATP-bicarbonate site) to the other (the pyruvate site). The activated carboxyl group is then transferred from carboxybiotin to pyruvate to form oxaloacetate. ...
Transforming growth factor β1
Transforming growth factor β1

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Ketosis



Ketosis /kɨˈtoʊsɨs/ is a metabolic state where most of the body's energy supply comes from ketone bodies in the blood, in contrast to a state of glycolysis where blood glucose provides most of the energy. It is characterised by serum concentrations of ketone bodies over 0.5 millimolar, with low and stable levels of insulin and blood glucose. It is almost always generalized with hyperketonemia, that is, an elevated level of ketone bodies in the blood throughout the body. Ketone bodies are formed by ketogenesis when liver glycogen stores are depleted (or from metabolising medium-chain triglycerides). The main ketone bodies used for energy are acetoacetate and β-hydroxybutyrate, and the levels of ketone bodies are regulated mainly by insulin and glucagon. Most cells in the body can use both glucose and ketone bodies for fuel, and during ketosis, free fatty acids and glucose synthesis (gluconeogenesis) fuel the remainder.Longer-term ketosis may result from fasting or staying on a low-carbohydrate diet, and deliberately induced ketosis serves as a medical intervention for intractable epilepsy. In glycolysis, higher levels of insulin promote storage of body fat and block release of fat from adipose tissues, while in ketosis, fat reserves are readily released and consumed. For this reason, ketosis is sometimes referred to as the body's ""fat burning"" mode.
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