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Swan Gantz Catherter and the Meaning of its Readings Justin Chandler Surgical Critical Care Fellow The Pulmonary Artery Catheter and Its History The Pulmonary Artery Catheter and Its History  Cardiac catheterization dates back to Claude Bernard   used it on animal models Clinical application begins with Werner Forssmann in the 1930s  inserted a catheter into his own forearm, guided it fluoroscopically into his right atrium, and took an Xray picture of it The Pulmonary Artery Catheter and Its History  The pulmonary artery catheter introducted in 1972    Frequently referred to as a SwanGanz catheter, in honor of its inventors Jeremy Swan and William Ganz, from Cedars-Sinai Medical Center The “sail” or balloon tip was a modification of the simple portex tubing method developed by Ronald Bradley Ganz added the thermistor Indications  Diagnostic indications:          Shock states Differentiation of high vs low pressure pulmonary edema Primary pulmonary hypertension Valvular disease Intracardiac shunts Cardiac tamponade Pulmonary embolus Monitoring and management of complicated acute myocardial infarction      Assessing hemodynamic response to therapies Management of multiorgan failure Severe burns Hemodynamic instability after cardiac surgery Assessment of response to treatment in patients with primary pulmonary hypertension Therapeutic indications:  Aspiration of air emboli Placement  Place an introducer    Hand ports off to RN, inspect and have RN flush catheter      R IJ > L SC > R SC > L IJ Femoral is an option if CCO, leave tip in the holder to calibrate Place swandom on catheter Insert about 15cm and the inflate balloon Slowly and steadily advance catheter watching the waveforms NB When wedged, not the volume required Placement Typical Cather Insertion Landmarks Anatomic Structure Distance Right atrium 20 to 25 cm Right ventricle 30 to 35 cm Pulmonary artery 40 to 45 cm Pulmonary capillary wedge 45 to 55 cm Conformation Zones of West Insertion tips    Turn CVP off! Once in the RV  advance to PA quickly to avoid coiling, ventricular arrhythmia. Difficulty getting into PA Valsava  Calciun iv  HOB up  Basics to Remember  Hemodynamic variables should not be interpreted in isolation Integration of variables with the clinical situation increases the accuracy of assessment  Trends are generally more useful than isolated variables at a single point in time  What does a PAC tell us?  Direct measurements     CVP PA (systolic and diasotolic) PAOP (wedge) SvO2 (mixed)  Calculated data      Stroke volume (SV/SVI) Cardiac output (CO/CI) Vascular resistance (SVR,PVR) Oxygen delivery Extended calculations    CCO Stroke work End diastolic volume, EF Variables of Hemodynamics Variable Assessment Stroke volume/index Pump performance Cardiac output/index Blood flow CVP/RAP R heart filling pressure PAOP/Wedge L heart filling pressure SvO2 Tissue oxygenation Normal Values Variable Value Stroke volume (SVI) 50-100 mL/beat (25-45) Cardiac output (CI) 4-8 L/min(2.5-4.0) CVP/RAP 2-6 mmHg PAOP/Wedge 8-12 mmHg SvO2 0.60 – 0.75 Additional Values Variable Value SVR (SVRI) 900-1300 (1900-2400)dynes sec/cm5 PVR 40-150 dynes sec/cm5 MAP 70-110 mmHg Equations to Remember      CO = SV x HR or SV = CO / HR SV = EDV – ESV or EDV x EF C = ΔV/ΔP SVR = (MAP – CVP) x 80 / CO LSW = (MAP – LVEDP) x SV x 0.0136 To convert to index: divide by BSA BSA = [Ht + Wt-60]/100 (in cm & kg) Cardiac Output    Major determinate of oxygenation delivery to tissue Abnormalities are viewed in the context of SV/SI and SvO2 Remember: a normal CO/CI may be associated with a low SV/SI in the presence of tachycardia Factors Affecting CO  Physiologic     Dysrhythmias Septal defects Tricuspid regurg Respirations  Technical    Bolusing technique Themistor malfunction Factors not affecting CO:     Iced vs room temp NSS vs D5 Pt elevation (<45o) 5 cc vs 10 cc CO Measurement  Typically done with thermodilution method A cold solution of fixed volume is injected and a thermsitor measures the change in temperature  The area under the curve is integrated to calculate the CO  The waveform should be examined to determine if the technique was good   If the accuracy is in doubt, the Fick method may be used CO Waveforms Fick Method  CO = VO2 / [CaO2 – CvO2] * 10  SaO2 and SvO2 often substituted   CO = VO2 / [SaO2 – SvO2] * Hgb * 1.34* 10 VO2 is not usually measured Can use 3.5 mL/kg or 125 mL/m2  If metabolic rate is abnormal, the calculation may be incorrect  Stroke volume  If low Inadequate volume (hypovolemia)  Impaired ventricular contraction (ischemia/infarction)  Increased SVR (drugs)  Valve dysfunction (MVR)   If high  Low vascular resistance (sepsis, drugs) CVP  Reflects R heart diastolic function and volume status   60-70% of blood volume is in venous system Abnormalities are viewed in the context of SV/SI If high (>6) implies right ventricular dysfunction, especially if SV is low  If low (< 2) implies hypovolemia especially if SV is low  CVP  High        Hypervolemia RV failure Tricupid stenois/regurg Cardiac tamponade Cardiac pericarditis Pulm HTN Chronic LV failure  Low   Hypovolemia Venodiliation PAOP  Reflects left ventricular end diastolic volume   Assumes a static column of blood from ventricle to catheter during diastole and consistent compliance Abnormalities are viewed in the context of SV/SI   If high (>18) implies left ventricular dysfunction, especially if SV is low If low (< 8) implies hypovolemia especially if SV is low PAOP  High        Hypervolemia LV failure Cardiac tamponade Cardiac pericarditis Mitral stenosis/regurg Atrial myxoma Pulmonary diseases  Low  Hypovolemia  Aortic regurg Elevated LVEDP (>25mmHg) with decreased compliance  PAOP  Conditions in Which PAD Does Not Equal PAOP (1 – 4 mm Hg) Increased PVR  Pulmonary hypertension  Cor pulmonale  Pulmonary embolus  Eisenmenger’s syndrome  Filling Pressures  If low, but other parameters are normal may only require observation If CO/CI are also low, treatment may be warranted  If SvO2 and/or SV/SI are also low treatment is needed  Pulmonary congestion also warrants treatment  SvO2    Reflects the balance between oxygen delivery and utilization The larger the abnormality, the greater the risk of hypoxemia Remember: a normal or high SvO2 may represent a threat to tissue oxygenation SvO2  A low SvO2 usually warrants investigation  Evaluate:  SV/SI  May require treatment, even if CVP/PAOP are normal Hb/Hct  SaO2 (>90%)  Reasons for oxygen consumption to be elevated   Abnormally high SvO2 may be indicative of a septal defect Continuous Cardiac Output  Newer generation catheter Uses continuous cardiac output measurements without need for bolusing  Allows for right heart “volumetric” data  RVEDV, RVEF, and RVSV  RVSW and RVSWI   Also provides continuous SvO2 measurements Additional Reference Numbers (R)EDV (SV/EF) 100-160 ml (R)EDVI 60-100 ml/m2 ESV (EDV-SV) 50-100 ml ESVI 30-60 ml/m2 (*) LVSWI 45-75 gm-m/m2/beat RVSWI 5-10 gm-m/m2/beat Waveform Analysis  Changes in pressure waveforms are due to: Blood entering or leaving a chamber  Changes in wall tension (contraction/relaxation)    Are always preceded by electrical stimulation Waveforms are also affected by changes in intrathoracic pressure (present as rhythmic changes) The Waves The Waves - CVP/RA  The a wave occurs with atrial contraction   The c wave occurs with closure of the tricuspid valve   It occurs at the end of the QRS (RST junction) The v wave occurs with filling of the atria with the tricupid valve closed   It occurs after the P wave in the PR-interval Occurs after the T wave The mean of the a wave is the CVP The Waves - RV   Has a sharp, rapid upstroke and a rapid down stroke Falls to near zero The Waves - PA  Characteristics      Rapid up stroke and down stroke Dicrotic notch (closure of pulmonic valve) Smooth runoff End systolic wave occurs after the T wave End diastolic occurs after the QRS The Waves - PAOP  Characteristics  May contain 3 waves  a atrial contraction    c closure of mitral valve (often absent) v filling of atria with mitral valve closed   Found after the QRS Found well after the T Mean PAOP  Average the a wave a Wave Differential  Large      Tricuspid or mitral regurg Decreased ventricular compliance Loss of A-V synchrony Junctional rhythms Tachycardia (>130)  Absent     A-fib Junctional rhythms Paced rhythms Ventricular rhythms v Wave Differential  Large    Tricuspid or mitral regurg Noncompliant atrium Ventricular ischemia/failure  Absent    V-fib Asystole PEA Diagnosis by Waveform  Mitral insuffiency    Prominent v wave Proximity of v and a waves Returns to a more normal configuration after afterload reduction Diagnosis by Waveform  VSD    Presents with increased SvO2 Note the delay in the v wave May respond to afterload reducers Diagnosis by Waveform  Cardiac Tamponade   As with constrictive pericarditis, there is equalization of diastolic pressures Note the loss of the y descent in cardiac tamponade Diagnosis by Waveform  Constrictive pericarditis   Note the equalization of the diastolic pressures Unlike tamponade, there is an exaggeration of the y descent due to a more rigid pericardium Points to remember  Intrathoracic pressure during inhalation and exhalation cause pressures in the heart to vary  Therefore all pressures should be measured at endexpiration when intrathoracic pressure is closest to zero Points to Remember  Limitations in hemodynamic monitoring  Ventricular filling pressures do not always accurately reflect ventricular filling volume    The PAOP is normally slightly (1-5 mm Hg) less than the PAD pressure    The pressure-volume relationship depends upon ventricular compliance If compliance changes, the pressure-volume relationship changes This relationship stills exists with pulm hypertension due to LV failure However, with an ↑ PVR or tachycardia (>125 bpm) this relationship may breakdown and the PAD becomes significantly higher than the PAOP The PAOP may not equal LVEDP when      there is high alveolar pressures when the catheter tip is above the left atrium severe hypovolemia tachycardia (130 bpm) in mitral stenosis. Points to remember  Calculated variables (e.g. SVR, PVR & SV/SI) are limited in value due to assumptions made in their calculations Complications  Air embolism    Arrhythmias    S&S: hypoxemia, cyanosis, hypotension/syncope, “machinery murmur”, elevated CVP, arrest Tx: place in left lateral trendelenburg, FiO2 of 100%, attempt aspiration of air, CPR Prevention: keep balloon inflated, minimize insertion time Tx: removal of catheter, ACLS Heart blocks   Typically RBBB occurs, so avoid PACs in LBBB Tx: transvenous/transcutaneous pacers, PACs with pacer Complications  Knotting    Prevention: minimize insertion time, avoid pushing agaist resistance, verify RA to RV transition Tx: check CXR, attempt to unknot Pulmonary artery rupture    S&S: hypoxemia, hemoptysis, circ collapse Prevention: withdraw PAC if spontaneously wedges or wedges with < 1.25 cc of air Tx: stop anti-coagulation, affected side down, selective bronchial intubation, PEEP, surgical repair (CPB or ECMO) Complications  Pulmonary infarction  Prevention       Avoid distal positioning of catheter Check CXR Monitor PA EDP instead of PAOP Pull back if spontaneous wedge occurs Limit air in cuff (pull back if < 1.25 cc) Tx    CXR Check cath position, deflate and withdraw Observe Complications  Infection  Prevention!         Aseptic technique Dead-end caps Sterile sleeve (swandom) Minimize entry into system Avoid glucose containing fluid Avoid over changing of tubing, etc (72-96 hr) Remove catheter ASAP Thrombus   Prevention – continuous flush +/- heparin Tx – lytic agent ; remove catheter Emerging Technology  Devices exist that use arterial pressure waveform to continuously measure cardiac output    Variations of the arterial pressure are proportional to stroke volume Several studies demonstrate that SVV has a high sensitivity and specificity in determining if a patient will respond (increasing SV) when given volume (“preload responsiveness”) Limitations   Only used in mechanically ventilated pts Wildly inaccurate when arrhythmias are present Emerging Technology  Impedance Cardiography (ICG)   Converts changes in thoracic impedance to changes in volume over time ICG offers noninvasive, continuous, beat-by-beat measurements of:           Stroke Volume/Index (SV/SVI) Cardiac Output/Index (CO/CI) Systemic Vascular Resistance/Index (SVR/SVRI) Velocity Index (VI) Thoracic Fluid Content (TFC) Systolic Time Ratio (STR) Left Ventricular Ejection Time (LVET) Pre-Ejection Period (PEP) Left Cardiac Work/Index (LCW/LCWI) Heart Rate In a Nutshell  Right heart failure   Hypotension  Left heart failure   Low CI, high PVR  High PAOP, low CI, high SVR    High PAOP, low CI, CVP ≈ POAP   Low CVP, PAOP, CI High SVR Cardiogenic  Tamponade  Hypovolemia High CVP,PAOP, SVR Low CI Sepsis   Low CVP, PAOP, SVR High CI References  Pulmonary Artery Catheter Education Project  http://www.pacep.org  Chatterjee, The Swan-Ganz Catheters: Past, Present, and Future: A Viewpoint. Circulation 2009;119;147-152  Edwards Scientific  http://ht.edwards.com/presentationvideos/powerpoint/strokevolumevariation/s trokevolumevariation.pdf Question #1  Which one of the following statements is most correct? A) A CVP <2 mmHg usually reflects hypovolemia if the SVI is>45 mL/beat/M2 B) A CVP >6 mmHg usually reflects RV failure if the SVI is <25 mL/beat/M2 C) A PAOP >18 mmHg usually reflects LV failure if the SVI is >45 mL/beat/M2 D) A PAOP <8 mmHg usually reflects hypovolemia if the SVI is >25 mL/beat/M2 Answer #1  Which one of the following statements is most correct? A) A CVP <2 mmHg usually reflects hypovolemia if the SVI is>45 mL/beat/M2 B) A CVP >6 mmHg usually reflects RV failure if the SVI is <25 mL/beat/M2 C) A PAOP >18 mmHg usually reflects LV failure if the SVI is >45 mL/beat/M2 D) A PAOP <8 mmHg usually reflects hypovolemia if the SVI is >25 mL/beat/M2 Question #2  Identify the condition most consistent with the following hemodynamic profile: SvO2 ... 0.50 ... PAOP ... 21 mmHg CI ... 2.2 L/min/M2 ...CVP/RA ... 4 mmHg SVI ... 23 ml/beat M2 ... HR ... 98 A) Hypovolemia B) Hypervolemia C) LV dysfunction/failure D) Bilateral ventricular failure Answer #2  Identify the condition most consistent with the following hemodynamic profile: SvO2 ... 0.50 ... PAOP ... 21 mmHg CI ... 2.2 L/min/M2 ...CVP/RA ... 4 mmHg SVI ... 23 ml/beat M2 ... HR ... 98 A) Hypovolemia B) Hypervolemia C) LV dysfunction/failure D) Bilateral ventricular failure Question #3  Identify the condition most consistent with the following hemodynamic profile: SvO2 ... 0.47 ... PAOP ... 4 mm Hg CI ... 2.0 L/min/M2 ... CVP/RA ... 2 mm Hg SVI ... 19 ml/beat/M2 ... HR ... 111 A) Hypovolemia B) Hypervolemia C) LV dysfunction/failure D) Bilateral ventricular failure Answer #3  Identify the condition most consistent with the following hemodynamic profile: SvO2 ... 0.47 ... PAOP ... 4 mm Hg CI ... 2.0 L/min/M2 ... CVP/RA ... 2 mm Hg SVI ... 19 ml/beat/M2 ... HR ... 111 A) Hypovolemia B) Hypervolemia C) LV dysfunction/failure D) Bilateral ventricular failure Question #4  Which of the combined set of hemodynamic values is of greatest concern? A) CO = 6.9 L/min; CI = 3.8 L/min/M2 SV = 63 mL/beat; SVI = 34 mL/beat/M2 BP = 102/52 mm Hg SvO2 = 0.83  B) CO = 4.3 L/min; CI = 2.5 L/min/M2 SV = 43 mL/beat; SVI = 25 mL/beat/M2 BP = 94/62 mm Hg SvO2 = 0.64  C) CO = 6.3 L/min; CI = 3.7 L/min/M2 SV = 64 mL/beat; SVI = 37 mL/beat/M2 BP = 90/56 mm Hg SvO2 = 0.75  D) CO = 3.8 L/min; CI =2.3 L/min/M2 SV = 73 mL/beat; SVI = 43 mL/beat/M2 BP = 100/58 mm Hg SvO2 = 0.72 Answer #4  Which of the combined set of hemodynamic values is of greatest concern? A) CO = 6.9 L/min; CI = 3.8 L/min/M2 SV = 63 mL/beat; SVI = 34 mL/beat/M2 BP = 102/52 mm Hg SvO2 = 0.83  B) CO = 4.3 L/min; CI = 2.5 L/min/M2 SV = 43 mL/beat; SVI = 25 mL/beat/M2 BP = 94/62 mm Hg SvO2 = 0.64  C) CO = 6.3 L/min; CI = 3.7 L/min/M2 SV = 64 mL/beat; SVI = 37 mL/beat/M2 BP = 90/56 mm Hg SvO2 = 0.75  D) CO = 3.8 L/min; CI =2.3 L/min/M2 SV = 73 mL/beat; SVI = 43 mL/beat/M2 BP = 100/58 mm Hg SvO2 = 0.72 Question #5  Immediate treatment of pulmonary artery rupture may include all of the following except: A) Discontinuation of anticoagulation B) Placing patient in lateral position with unaffected side down. C) Selective bronchial intubation D) PEEP Answer #5   Immediate treatment of pulmonary artery rupture may include all of the following except: A) Discontinuation of anticoagulation B) Placing patient in lateral position with unaffected side down. C) Selective bronchial intubation D) PEEP E) Hire a lawyer
 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
                                             
                                             
                                             
                                             
                                             
                                             
                                             
                                             
                                             
                                             
                                            