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Facts File 2 1.Largest Vein inferior venacava 2.Largest artery Aorta 3.Smallest blood vessel Capillary 4.Animal with highest BP Giraffe 5.Vertebrate with White blood Antarctic fish 6.Lung fish has Two auricles and one ventricle 7.Frog has Two pairs of lymph hearts 8.Heart of fish Venous heart 9.Animal without heart Amphioxus and Nereis 10.Foramen Panizza Present between the systemic arches of the heart 11.Weight of human heart Male – 300 Gm. Female – 250 Gm 12.Coronory Angiography Used to detect blocks in the arteries 13.Excess calcium Increases heart beat 14.Papillary muscles Present in the heart of mammals 15.Keber’s gland Pericardial gland present in Fresh water mussel 16.Insect with haemoglobin Chironomus larva of Chironomus fly 17.Blood Worm Chironomus larva 18.Vasa Vasorum Blood vessel gives blood to blood vessel 19.Largest heart Blue Whale 20.Tread Mill Test – TMT Used to check the effieciency of heart 21.Bicuspid and Tricuspid Terms used for heart valves and crown of tooth 22.Rh factor Appears in foetus from 10th week 23.Antibodies A and B Appears in foetus from 4-8th months after birth 24.Cardiac index Minute volume per sq.m – 3.3 lit / min / sq.m 25.William Harvey Discovered blood circulation 26.Angiology Study of blood vessels 27.Cardiology Study of heart 28.Arteriovenous heart Double circuilation Lung fish Amphibia , Reptiles, Birds , Mammals 29. Complete double circulation Birds , Mammals , Crocodile , Alligator , Gravialis 30.Coronary Sulcus Groove present on the surface of Heart 31.Right auricle Receives blood from – Superior and Inferior venacavae and Coronary sinus 32.Valve of Thebesius Present in coronary sinus 33.Tricuspid valve Between right auricle and right ventricle 34.Chordae tendinae Muscle fibers connectin valves to wall of ventricle 35.Semilunar valves Present in aorta 36.Wall of heart Outer Epicardium , Middle Myocardium – Inner Endocardium 37.Cardiac cycle Atrial systole + Ventricular systole + Joint diastole 38.Atrial systole 0.18 seconds 39.Atrial diastole 0.08 seconds 40.Ventricular systole Relaxation of atria and Cotraction of ventricle 41.Ventricular systole 0.3 seconds 42.Ventricular diastole 0.32 seconds 43.Joint diastole 0.4 seconds 44.Cardiac cycle 0.88 seconds 45.Dupp sound Closing of semilunar valves 46.Pulse pressure Difference between systolic and diastolic pressure – Normal value 40mm Hg 47.SA node Heart beat first originate – highest rate of rhythemicity 48.Normal heart rate 70-72 / sec. In male , 80 –82 in female and children 49.Cardiac output Blood pumped in to aorta per minute – 5 litres 50.Neurogenic heart 51.Myogenic heart 52.Pace Setter 53.Bundle of His 54.Purkinje fibres 55.Bradycardia 56.Tachycardia 57.Blue baby 58.Heart rate 59.Epinephrine 60.Nor epinephrine 61.Grave yard of RBC 62.Cords of Billroth 63.Diapedesis 64.Heart murmur 65.ESR 66.Hepatic portal vein 67.Artery 68.Veins 69.Erythroblasts 70.Erythropoiesis 71.Erythropoetin 72.Lymph glands 73.Spleen 74.Classical blood groups 75.Rh antigen 76.Antigen 77.Antibody 78.Blood clotting factors 79.Factor VIII 80.Factor IX 81.Haemophilia 82.Buffer of blood 83.Pulse beat 84.Tricuspid valve 85.Bicuspid valve 86.Maximum heart beat 87.RBC – WBC ratio 88.Wall of vein 89.Endothelium 90.Conduction of heart beat Contraction originate from nerve ganglions present on heart Insect heart Contraction originate from the muscle ( pace makers – SA and AV Nodes ) present on the heart - Vertebrate heart AV node Conducting fibres between SA and AV nodes Conducting fibres from Bundle of His to ventricle Slow heart rate - 60 / minute Increased heart rate – Above 72 / minute] Baby born with atrial or ventricular defect – Blue in colour due to venous blood More in old persons due to decreased elasticity of arteries Increases heart beat – Tachycardia Decreases heart rate – Bradycardia Spleen – destroy used RBC after 120 days Blood spaces of Spleen Amoeboid movement of WBC through blood capillary Sound of heart due to defective valve Erythrocyte Sedimentation Rate – Test to detect disease – Normal value 30. Increases in infections like T.B Gastric + Intestinal + Splenic veins Thick wall , Elastic , Contractile ,no valves Thin wall ,Non elastic ,Non contractile , Valved Mother cells of RBC – Present in bone marrow – nucleated Formation of RBC – Folic acid , Iron essential –Occurs in red bone marrow of ribs , vertebrae , long bones Hormone stimulating RBC formation Rich in WBC – destroy pathogens Lymph gland – filter dead RBC from blood A,B,AB,O system – Introduced by Karl Landsteiner – 1900 Rhesus Factor – Identified in Rhesus macaca by Landsteiner and Weiner – 90 % people Rh positive – 10 % Rh negative Mismatching causes Erythroblastosis foetalis – No natural antibody for Rh antigen in the blood - Antibody develop by Isoimmunization when Rh Positive blood is transfused in to Rh negative blood. Takes six months Also called agglutinogen Also called agglutinin 12 numbers Anti haemophilic factor – AHF – absence causes Haemophilia A Absence causes Haemophilia B Royal disease ( found out in the family of queen Victoria ) Bleeders disease.Genotype – Hh / Hh Females are carriers – h / h male haemophilic – Male is Hemizygous – only one gene for haemophilia is sufficient to produce disease since male has only one X chromosome NaHCO3 –sodium bi carbonate Beat felt in arteries Found between right auricle and right ventricle Also called Mitral valve – between left auricle and ventricle Mouse 600 : 1 Tunica media Inner lining of blood capillary SA node – AV node – Bundle of His – Purkinje system – Ventricle 91.Blood vessel to diaphragm 92.Blood vessel to brain 93.Largest heart 94.Heart transplantation Phernic Carotid artery Elephant Christian Bernard