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Principles of Health Science Infectious Diseases Types Of Viruses • • • • • • • Common cold Measles Mumps Chicken pox Influenza Herpes AIDS Common Cold • What is the common cold, and what causes it? • The common cold is a self-limited contagious illness that can be caused by a number of different types of viruses. The common cold is medically referred to as a viral upper respiratory tract infection. Symptoms of the common cold may include cough, sore throat, nasal congestion, runny nose, and sneezing. More than 200 different types of viruses are known to cause the common cold, with rhinovirus causing approximately 30%-35% of all adult colds. Other commonly implicated viruses include coronavirus, adenovirus, respiratory syncytial virus, and parainfluenza virus. Because so many different viruses can cause a cold and because new cold viruses constantly develop, the body never builds up resistance against all of them. For this reason, colds are a frequent and recurring problem. In fact, children in preschool and elementary school can have six to 12 colds per year while adolescents and adults typically have two to four colds per year. The common cold occurs most frequently during the fall and winter months. Transmission • How is the common cold transmitted? • The common cold is spread either by direct contact with infected secretions from contaminated surfaces or by inhaling the airborne virus after individuals sneeze or cough. Person-to-person transmission often occurs when an individual who has a cold blows or touches their nose and then touches someone or something else. A healthy individual who then makes direct contact with these secretions can subsequently become infected, often after their contaminated hands make contact with their own eyes or nose. A cold virus can live on objects such as pens, books, telephones, computer keyboards, and coffee cups for several hours and can thus be acquired from contact with these objects. Signs and Symptoms • The cold may begin with a runny nose with clear nasal discharge, which later may become yellowish or greenish in color. Infants and children may also become more fussy and have decreased appetite. • The symptoms of the common cold will typically last anywhere from four to 14 days, with most individuals improving in one week. • Does it have anything to do with exposure to cold weather? • Though the common cold usually occurs in the fall and winter months, the cold weather itself does not cause the common cold. Rather, it is thought that during cold-weather months people spend more time indoors in close proximity to each other, thus facilitating the spread of the virus. For this same reason, children in day care and school are particularly prone to acquiring the common cold. • Measles • Measles is a very contagious (easily spread) illness • The infection is spread by contact with droplets from the nose, mouth, or throat of an infected person. Sneezing and coughing can put contaminated droplets into the air. • Those who have had an active measles infection or who have been vaccinated against the measles have immunity to the disease. Before widespread vaccination, measles was so common during childhood that most people became sick with the disease by age 20. The number of measles cases dropped over the last several decades to almost none in the U.S. and Canada. However, rates have started to rise again recently. • Some parents do not let their children get vaccinated because of unfounded fears that the MMR vaccine, which protects against measles, mumps, and rubella, can cause autism. Large studies of thousands of children have found no connection between this vaccine and autism. Not vaccinating children can lead to outbreaks of a measles, mumps, and rubella -- all of which are potentially serious diseases of childhood Measles Measles • • • • • • • • • Symptoms Symptoms usually begin 8 - 12 days after you are exposed to the virus. This is called the incubation period. Symptoms may include: Bloodshot eyes Cough Fever Light sensitivity (photophobia) Muscle pain Rash – – – – – • • • • Usually appears 3 - 5 days after the first signs of being sick May last 4 - 7 days Usually starts on the head and spreads to other areas, moving down the body Rash may appear as flat, discolored areas (macules) and solid, red, raised areas (papules) that later join together Itchy Redness and irritation of the eyes (conjunctivitis) Runny nose Sore throat Tiny white spots inside the mouth (Koplik's spots) Measles • • • • • • • Treatment There is no specific treatment for the measles. The following may relieve symptoms: Acetaminophen (Tylenol) Bed rest Humidified air Some children may need vitamin A supplements. Vitamin A reduces the risk of death and complications in children in less developed countries, where children may not be getting enough vitamin A. People who don't get enough vitamin A are more likely to get infections, including measles. It is not clear whether children in more developed countries would benefit from supplements Mumps • Mumps is a contagious disease that leads to painful swelling of the salivary glands. The salivary glands produce saliva, a liquid that moistens food and helps you chew and swallow Mumps Mumps • Causes, incidence, and risk factors • The mumps are caused by a virus. The virus is spread from person-to-person by respiratory droplets (for example, when you sneeze) or by direct contact with items that have been contaminated with infected saliva. • Mumps most commonly occurs in children ages 2 - 12 who have not been vaccinated against the disease. However, the infection can occur at any age. The time between being exposed to the virus and getting sick (incubation period) is usually 12 - 24 days. Signs and Symptoms • • • • • • • • • • • Symptoms Face pain Fever Headache Sore throat Swelling of the parotid glands (the largest salivary glands, located between the ear and the jaw) Swelling of the temples or jaw (temporomandibular area) Other symptoms of this disease that can occur in males: Testicle lump Testicle pain Scrotal swelling • Treatment • There is no specific treatment for mumps. Ice or heat packs applied to the neck area and acetaminophen (Tylenol) may help relieve pain. Do not give aspirin to children with a viral illness because of the risk of Reye syndrome. • You can also relieve symptoms with: • Extra fluids • Soft foods • Warm salt water gargles ChickenPox • Chickenpox is a viral infection in which a person develops extremely itchy blisters all over the body. It used to be one of the classic childhood diseases. However, it has become much less common since the introduction of the chickenpox vaccine • • • • • • • Causes, incidence, and risk factors Chickenpox is caused by the varicella-zoster virus, a member of the herpesvirus family. The same virus also causes herpes zoster (shingles) in adults. Chickenpox can be spread very easily to others. You may get chickenpox from touching the fluids from a chickenpox blister, or if someone with the disease coughs or sneezes near you. Even those with mild illness may be contagious. A person with chickenpox become contagious 1 to 2 days before their blisters appear. They remain contagious until all the blisters have crusted over. Most cases of chickenpox occur in children younger than 10. The disease is usually mild, although serious complications sometimes occur. Adults and older children usually get sicker than younger children. Children whose mothers have had chickenpox or have received the chickenpox vaccine are not very likely to catch it before they are 1 year old. If they do catch chickenpox, they often have mild cases. This is because antibodies from their mothers' blood help protect them. Children under 1 year old whose mothers have not had chickenpox or the vaccine can get severe chickenpox. Severe chickenpox symptoms are more common in children whose immune system does not work well because of an illness or medicines such as chemotherapy and steroids. • • • • • • • • • • • Symptoms Most children with chickenpox have the following symptoms before the rash appears: Fever Headache Stomach ache The chickenpox rash occurs about 10 to 21 days after coming into contact with someone who had the disease. The average child develops 250 to 500 small, itchy, fluid-filled blisters over red spots on the skin. The blisters are usually first seen on the face, middle of the body, or scalp After a day or two, the blisters become cloudy and then scab. Meanwhile, new blisters form in groups. They often appear in the mouth, in the vagina, and on the eyelids. Children with skin problems such as eczema may get thousands of blisters. Most pox will not leave scars unless they become infected with bacteria from scratching. Some children who have had the vaccine will still develop a mild case of chickenpox. They usually recover much more quickly and have only a few pox (less than 30). These cases are often harder to diagnose. However, these children can still spread chieckenpox to others. • • • • • • • • • • • • • • • Treatment Treatment involves keeping the person as comfortable as possible. Here are things to try: Avoid scratching or rubbing the itchy areas. Keep fingernails short to avoid damaging the skin from scratching. Wear cool, light, loose bedclothes. Avoid wearing rough clothing, particularly wool, over an itchy area. Take lukewarm baths using little soap and rinse thoroughly. Try a skin-soothing oatmeal or cornstarch bath. Apply a soothing moisturizer after bathing to soften and cool the skin. Avoid prolonged exposure to excessive heat and humidity. Try over-the-counter oral antihistamines such as diphenhydramine (Benadryl), but be aware of possible side effects such as drowsiness. Try over-the-counter hydrocortisone cream on itchy areas. Medications that fight the chickenpox virus are available but not given to everyone. To work well, the medicine usually must be started within the first 24 hours of the rash. Antiviral medication is not usually prescribe to otherwise healthy children who do not have severe symptoms. Adults and teens, who are at risk for more severe symptoms, may benefit from antiviral medication if it is given early. Antiviral medication may be very important in those who have skin conditions (such as eczema or recent sunburn), lung conditions (such as asthma), or who have recently taken steroids. Some doctors also give antiviral medicines to people in the same household who also develop chickenpox, because they will usually develop more severe symptoms. DO NOT GIVE ASPIRIN OR IBUPROFEN to someone who may have chickenpox. Use of aspirin has been associated with a serious condition called Reyes syndrome. Ibuprofen has been associated with more severe secondary infections. Acetaminophen (Tylenol) may be used. A child with chickenpox should not return to school or play with other children until all chickenpox sores have crusted over or dried out. Adults should follow this same rule when considering when to return to work or be around others. Influenza • Influenza, commonly known as "the flu," is a highly contagious viral infection of the respiratory tract. It affects all age groups, though kids tend to get it more often than adults Signs and Symptoms • • • • • • • • • • • • • • • • The flu is often confused with the common cold, but flu symptoms usually are more severe than the typical sneezing and stuffiness of a cold Symptoms, which usually begin about 2 days after exposure to the virus, can include: fever chills headache muscle aches dizziness loss of appetite tiredness cough sore throat runny nose nausea or vomiting weakness ear pain diarrhea • Duration • After 5 days, fever and other symptoms have usually disappeared, but a cough and weakness may continue. • All symptoms are usually gone within a week or two. However, it's important to treat the flu seriously because it can lead to pneumonia and other life-threatening complications, particularly in infants, senior citizens, and people with longterm health problems • Contagiousness • The flu is contagious, spread by virusinfected droplets that are coughed or sneezed into the air. People who are infected are contagious from a day before they feel sick until their symptoms have ended (about 1 week for adults, but this can be longer for young kids). • The flu usually occurs in small outbreaks, but epidemics — when the illness spreads rapidly and affects many people in an area at the same time — tend to occur every few years. Epidemics often peak within 2 or 3 weeks after the first cases occur • Treatment • Cases of the flu rarely require specific medical treatment. But some people with chronic medical conditions (such as asthma, diabetes, and HIV) or children under 2 years old might become sicker with the flu and may have a greater risk of complications. Some people with the flu need to be hospitalized • These at-home tips can help most otherwise healthy cope with the flu. Have them: • drink lots of fluids to prevent dehydration • get plenty of sleep and take it easy • take acetaminophen or ibuprofen to relieve fever and aches (do not give aspirin to children or teens as it may cause a rare but serious illness called Reye syndrome) • wear layers, since the flu often makes them cold one minute and hot the next (wearing layers — like a T-shirt, sweatshirt, and robe — makes it easy to add or subtract clothes as needed Herpes Viruses • A virus is a small infectious agent that can only replicate inside the cells of another organism. The word is from the Latin ''virus'' referring to poison and other noxious substances, first used in English in 1392. ''Virulent'', from Latin ''virulentus'' (poisonous), dates to 1400. A meaning of "agent that causes infectious disease" is first recorded in 1728, The term ''virion'' is also used to refer to a single infective viral particle. The plural is "viruses". • Viruses are too small to be seen directly with a light microscope. Viruses infect all types of organisms, from animals and plants to bacteria and archaea. although there are millions of different types. Viruses are found in almost every ecosystem on Earth and these minute structures are the most abundant type of biological entity. The study of viruses is known as virology, a sub-specialty of microbiology Herpes Herpes Herpes • What are the signs and symptoms of genital herpes? • Most people infected with HSV-2 are not aware of their infection. However, if signs and symptoms occur during the first outbreak, they can be quite pronounced. The first outbreak usually occurs within two weeks after the virus is transmitted, and the sores typically heal within two to four weeks. Other signs and symptoms during the primary episode may include a second crop of sores, and flu-like symptoms, including fever and swollen glands. However, most individuals with HSV-2 infection never have sores, or they have very mild signs that they do not even notice or that they mistake for insect bites or another skin condition • Is there a treatment for herpes? • There is no treatment that can cure herpes, but antiviral medications can shorten and prevent outbreaks during the period of time the person takes the medication. In addition, daily suppressive therapy for symptomatic herpes can reduce transmission to partners Herpes • Persons with herpes should abstain from sexual activity with uninfected partners when lesions or other symptoms of herpes are present. It is important to know that even if a person does not have any symptoms he or she can still infect sex partners. Sex partners of infected persons should be advised that they may become infected and they should use condoms to reduce the risk. Sex partners can seek testing to determine if they are infected with HSV. A positive HSV-2 blood test most likely indicates a genital herpes infection. AIDS • HIV stands for human immunodeficiency virus. It kills or damages the body's immune system cells. AIDS stands for acquired immunodeficiency syndrome. It is the most advanced stage of infection with HIV AIDS • HIV most often spreads through unprotected sex with an infected person. It may also spread by sharing drug needles or through contact with the blood of an infected person. Women can give it to their babies during pregnancy • The first signs of HIV infection may be swollen glands and flu-like symptoms. These may come and go a month or two after infection. Severe symptoms may not appear until months or years later in pregancy or childbirth Treatment of AIDS • There is no cure, but there are many medicines to fight both HIV infection and the infections and cancers that come with it. People can live with the disease for many years. Bacteria Bacteria • Bacteria are microscopic organisms whose single cells have neither a membrane-enclosed nucleus nor other membrane-enclosed organelles like mitochondria and chloroplasts. Another group of microbes, the archaea, meet these criteria but are so different from the bacteria in other ways that they must have had a long, independent evolutionary history since close to the dawn of life. In fact, there is considerable evidence that you are more closely related to the archaea than they are to the bacteria Fungi • Fungi are plant like organisms such as molds, yeasts, and mushrooms Ringworm • Ringworm is common, especially among children. However, it may affect people of all ages. It is caused by a fungus, not a worm like the name suggests Athletes Foot • Athlete's foot is an infection of the feet caused by fungus. The medical term is tinea pedis. Athlete's foot may last for a short or long time and may come back after treatment Protozoa • The protozoa are one-celled animals and the smallest of all animals. Most of them can only be seen under a microscope. They do breathe, move, and reproduce like multicelled animals. They live in water or at least where it is damp. Animals in this group include the paramecium, the euglena and the ameba. • Some protozoans are harmful to man as they can cause serious diseases. Others are helpful because they eat harmful bacteria and are food for fish and other animals Protozoa Parasite • an organism that lives on or in an organism of another species, known as the host, from the body of which it obtains nutriment Types of Parasites • Ticks • Mites • Mosquitoes Scabies • Scabies is an easily spread skin disease caused by a very small scabies is found worldwide among people of all groups and ages. It is spread by direct contact with infected people, and less often by sharing clothing or bedding. Scabies • Scabies is found worldwide among people of all groups and ages. It is spread by direct contact with infected people, and less often by sharing clothing or bedding. Sometimes whole families are affected. • The mites that cause scabies burrow into the skin and deposit their eggs, forming a burrow that looks like a pencil mark. Eggs mature in 21 days. The itchy rash is an allergic response to the mite Scabies • Symptoms • Itching, especially at night • Rashes, especially between the fingers • Treatment • Prescription medicated creams are commonly used to treat scabies infections. The most commonly used cream is permethrin 5%. Other creams include benzyl benzoate, sulfur in petrolatum, and crotamiton. Lindane is rarely used because of its side effects. • Creams are applied all over the body. The whole family or sexual partners of infected people should be treated, even if they do not have symptoms. Creams are applied as a one-time treatment or they may be repeated in 1 week. • Wash underwear, towels, and sleepwear in hot water. Vacuum the carpets and upholstered furniture. • For difficult cases, some health care providers may also prescribe medication taken by mouth to kill the scabies mites. Ivermectin is a pill that may be used. • Itching may continue for 2 weeks or more after treatment begins, but it will disappear if you follow your health care provider's treatment plan. You can reduce itching with cool soaks and calamine lotion. Your doctor may also recommend an oral antihistamine The Chain Of Infection • Links of the Chain • There are six links in the Chain of Infection. Each link must be intact in order for a disease to be transmitted and infect another person. The links of the chain include Infectious Agent, Reservoir, Portal of Exit, Mode of Transmission, Portal of Entry, and Susceptibility. The infectious disease process can be broken at any one of these links. Immunizations • Shots may hurt a little... but the diseases they can prevent can hurt a lot more! Immunization shots, or vaccinations, are essential. They protect against things like measles, mumps, rubella, hepatitis B, polio, diphtheria, tetanus and pertussis (whooping cough). Immunizations are important for adults as well as for children. Here's why. • Your immune system helps your body fight germs by producing substances to combat them. Once it does, the immune system "remembers" the germ and can fight it again. Vaccines contain germs that have been killed or weakened. When given to a healthy person, the vaccine triggers the immune system to respond and thus build immunity. • Before vaccines, people became immune only by actually getting a disease and surviving it. Immunizations are an easier and less risky way to become immune. Stages of Disease • • • • • Infection Incubation Stage Prodromal Stage Clinical or Illness Stage Recovery Stage Infection • This first stage begins when a host becomes infected with a pathogenic organism. • The organism enters the body and begins to grow and multiply Incubation Stage • this is the stage where the bacteria affects the body but your are not sick yet • At the end of this stage the person is highly contagious Prodromal Stage • early stage or symptoms of disease before characteristic symptoms appear. Clinical or Illness Stage • The stage where symptoms appear • Example: when a person has a cold, this is the stage where they start sneezing and nose starts running Salmonella • What is salmonellosis? • Salmonellosis is a type of food poisoning caused by the Salmonella bacterium. There are many different kinds of these bacteria. Salmonella serotype Typhimurium and Salmonella serotype Enteritidis are the most common types in the United States Salmonella • • • • • • • What causes salmonellosis? You can get salmonellosis by eating food contaminated with salmonella. This can happen in the following ways: Food may be contaminated during food processing or food handling. Food may become contaminated by the unwashed hands of an infected food handler. A frequent cause is a food handler who does not wash his or her hands with soap after using the bathroom. Salmonella may also be found in the feces of some pets, especially those with diarrhea. You can become infected if you do not wash your hands after contact with these feces. Reptiles, baby chicks and ducklings, and small rodents such as hamsters are particularly likely to carry Salmonella. You should always wash your hands immediately after handling one of these animals, even if the animal is healthy. Adults should also be careful that children wash their hands after handling reptiles, pet turtles, baby chicks or ducklings, or small rodents. Beef, poultry, milk, and eggs are most often infected with salmonella. But vegetables may also be contaminated. Contaminated foods usually look and smell normal. Symptoms of Salmonella • What are the symptoms? • Symptoms of salmonellosis include diarrhea, fever, and abdominal cramps. They develop 12 to 72 hours after infection, and the illness usually lasts 4 to 7 days. Most people recover without treatment. But diarrhea and dehydration • dehydration may be so severe that it is necessary to go to the hospital. Older adults, infants, and those who have impaired immune systems are at highest risk. • If you only have diarrhea, you usually recover completely, although it may be several months before your bowel habits are entirely normal. A small number of people who are infected with salmonellosis develop Reiter's syndrome, a disease that can last for months or years and can lead to chronic arthritis. Mononucleosis • What is mononucleosis? • Mononucleosis, also called "mono," is a common viral illness that can leave you feeling tired and weak for weeks or months. Mono goes away on its own, but lots of rest and good self-care can help you feel better. Causes of Mono • What causes mono? • Mono is caused by the Epstein-Barr virus (EBV). It is most often seen in adolescents and young adults. Children can get the virus, but it often goes unnoticed because their symptoms are mild. Older adults usually do not get mono, because they have immunity to the virus. • Mono can be spread through contact with saliva, mucus from the nose and throat, and sometimes tears. Because the virus can be spread through kissing, it has earned the nickname the "kissing disease." If you have mono, you can avoid passing the virus to others by not kissing anyone and by not sharing things like drinking glasses, eating utensils, or toothbrushes. • As soon as you get over mono, your symptoms will go away for good, but you will always carry the virus that caused it. The virus may become active from time to time without causing any symptoms. When the virus is active, it can be spread to others. Symptoms of Mono • What are the symptoms? • The most common symptoms of mono are a high fever, a severe sore throat, swollen glands and tonsils, and weakness and fatigue. Symptoms usually start 4 to 6 weeks after you are exposed to the virus. • Mono can cause the spleen to swell. Severe pain in the upper left part of your belly may mean that your spleen has burst. This is an emergency. Mononucleosis Treatment • How is it treated? • Usually only self-care is needed for mono. • Get plenty of rest. You may need bed rest, which could keep you away from school or work for a little while. • Gargle with salt water or use throat lozenges to soothe your sore throat. • Take acetaminophen (such as Tylenol) or ibuprofen (such as Advil) to reduce fever and relieve a sore throat and headaches. • Avoid contact sports and heavy lifting. Your spleen may be enlarged, and impact or straining could cause it to burst Conjunctivitis • Conjunctivitis is swelling (inflammation) or infection of the membrane lining the eyelids Conjunctivitis • Causes, incidence, and risk factors • The conjunctiva is exposed to bacteria and other irritants. Tears help protect the conjunctiva by washing away bacteria. Tears also contain enzymes and antibodies that kill bacteria. • There are many causes of conjunctivitis. Viruses are the most common cause. Other causes include: • Allergies (allergic conjunctivitis) • Bacteria • Certain diseases • Chemical exposure • Chlamydia • Fungi • Parasites (rarely) • Use of contact lenses (especially extended-wear lenses Symptoms • • • • • • • • • Symptoms Blurred vision Crusts that form on the eyelid overnight Eye pain Gritty feeling in the eyes Increased tearing Itching of the eye Redness in the eyes Sensitivity to light Treatment • Treatment • Treatment of conjunctivitis depends on the cause. • Allergic conjunctivitis may respond to allergy treatment. It may disappear on its own when the allergen that caused it is removed. Cool compresses may help soothe allergic conjunctivitis. • Antibiotic medication, usually eye drops, is effective for bacterial conjunctivitis. Viral conjunctivitis will disappear on its own. Many doctors give a mild antibiotic eyedrop for pink eye to prevent bacterial conjunctivitis. • You can soothe the discomfort of viral or bacterial conjunctivitis by applying warm compresses (clean cloths soaked in warm water) to your closed eyes Strep Throat • Strep throat is caused by Group A Streptococcus bacteria. It is the most common bacterial infection of the throat Causes, incidence, and risk factors Strep throat is most common in children between age 5 and 15, although anyone can get it. Strep throat is spread by person-to-person contact with nasal secretions or saliva. It commonly spreads among family or household members Symptoms of Strep Throat • • • • • • • • • • • • • • Symptoms Symptoms may be mild or severe. You usually start to feel sick about 2 to 5 days after you come in contact with the bacteria. Symptoms usually begin suddenly, and can include: Fever that begins suddenly and is often highest on the second day Red throat, sometimes with white patches Sore throat Headache Nausea Chills General ill feeling Loss of appetite and abnormal taste Swollen lymph nodes in the neck Difficulty swallowing Some strains of strep throat can lead to a scarlet fever-like rash. This rash is thought to be an allergic reaction to toxins made by the strep bacteria Treatment for Strep • • • • • • • • • • • Treatment Most sore throats are caused by viruses, not strep-related bacteria. Strep cannot be accurately diagnosed by symptoms or a physical exam alone. Many of the other causes of sore throats may have the same symptoms. Sore throats should only be treated with antibiotics if the strep test is positive. Antibiotics are taken to prevent rare but more serious health problems, such as rheumatic fever. Penicillin or amoxicillin is usually first tried. Antibiotics should be taken for 10 days, even though symptoms are usually gone after few days. The following tips may help your sore throat feel better: Drink warm liquids such as lemon tea or tea with honey. Gargle several times a day with warm salt water (1/2 tsp of salt in 1 cup water). Drink cold liquids or suck on popsicles. Suck on hard candies or throat lozenges. Young children should not be given such products because they can choke on them. A cool-mist vaporizer or humidifier can moisten and soothe a dry and painful throat. Try over-the-counter pain medications, such tylenol Strep Throat Tuberculosis Tuberculosis • Pulmonary tuberculosis (TB) is a contagious bacterial infection that involves the lungs, but may spread to other organs • Causes, incidence, and risk factors • Pulmonary tuberculosis (TB) is caused by the bacteria Mycobacterium tuberculosis (M. tuberculosis). You can get TB by breathing in air droplets from a cough or sneeze of an infected person. This is called primary TB. • In the United States, most people will recover from primary TB infection without further evidence of the disease. The infection may stay asleep or inactive (dormant) for years. However, in some people it can reactivate. • Most people who develop symptoms of a TB infection first became infected in the past. However, in some cases, the disease may become active within weeks after the primary infection Symptoms of TB • Symptoms • The primary stage of TB usually doesn't cause symptoms. When symptoms of pulmonary TB occur, they may include: • Cough (usually cough up mucus) • Coughing up blood • Excessive sweating, especially at night • Fatigue • Fever • Unintentional weight loss • Other symptoms that may occur with this disease: • Breathing difficulty • Chest pain • Wheezing Treatment of TB • Tuberculin skin test • Treatment • The goal of treatment is to cure the infection with drugs that fight the TB bacteria. Treatment of active pulmonary TB will always involve a combination of many drugs (usually four drugs). All of the drugs are continued until lab tests show which medicines work best. • The most commonly used drugs include: • Isoniazid • Rifampin • Pyrazinamide • Ethambutol Sexually Transmitted Diseases • Sexually transmitted diseases (STDs, venereal diseases) are among the most common infectious diseases in the United States today. STDs are sometimes referred to as sexually transmitted infections, since these conditions involve the transmission of an infectious organism between sex partners. More than 20 different STDs have been identified, and about 19 million men and women are infected each year in the United States, according to the CDC (2010). STD’S • STDs affect men and women of all ages and backgrounds, including children. Many states require that Child Protective Services be notified if children are diagnosed with an STD. • STDs have become more common in recent years, partly because people are becoming sexually active at a younger age, are having multiple partners, and do not use preventive methods to lessen their chance of acquiring an STD. • People can pass STDs to sexual partners even if they themselves do not have any symptoms. • Frequently, STDs can be present but cause no symptoms, especially in women (for example, chlamydia, genital herpes or gonorrhea). This can also occur in some men. Chlamydia • Chlamydia is a bacterial infection disease transmitted when people have sexual relations. It is the most common sexually transmitted disease (STD) in the United States, with over 2.8 million affected individuals each year. Among adults, about 5% of the population is estimated to be infected. Among sexually active adolescent females, about 10% are infected. • Infection with chlamydia is most commonly found among the following groups: • Young adults (24 years and younger) • People living in urban areas • African Americans • Those with lower social and economic status Causes of Chlamydia • Chlamydia Causes • Chlamydia is an infection caused by the bacterium Chlamydia trachomatis. The infection is transmitted in 2 ways: • From one person to another through sexual contact (oral, anal, or vaginal). • From mother to child with passage of the child through the birth canal. Chlamydia can cause pneumonia or serious eye infections in a newborn, especially among children born to infected mothers in developing countries • Chlamydia Symptoms in Women • No symptoms in 70% to 80% of cases (One study found that 3% of a sample of young adults 18 to 35 years of age had untreated chlamydia.) • Bleeding after sexual relations or between menstrual periods • Lower abdominal pain and burning pain during urination • Discharge from the vagina • Chlamydia Symptoms in Men • Like women, men who are infected may not show symptoms. Estimates of those with no symptoms range from 25% to 50% of infected men. • Discharge from the penis • Pain, burning during urination • Inflammation or infection of a duct in the testicles, tenderness or pain in the testicles • Chlamydia Treatment • Chlamydia Medications • The health care practitioner may prescribe a single-dose antibiotic, such as azithromycin (Zithromax), taken as a pill. On the other hand, the doctor may choose an antibiotic, such as doxycycline (Atridox, Bio-Tab), to be taken as a pill twice a day for a week. Up to 95% of people will be cured after one course of antibiotics AIDS • What is the history of HIV, and when was HIV discovered? • The history of the human immunodeficiency virus (HIV) and acquired immunodeficiency syndrome (AIDS) dates back to 1981, when homosexual men with symptoms of a disease that now are considered typical of AIDS were first described in Los Angeles and New York. The men had an unusual type of lung infection (pneumonia) called Pneumocystis carinii (now known as Pneumocystis jiroveci) pneumonia (PCP) and rare skin tumors called Kaposi's sarcomas. The patients were noted to have a severe reduction in a type of cell in the blood (CD4 cells) that is an important part of the immune system. These cells, often referred to as T cells, help the body fight infections. Shortly thereafter, this disease was recognized throughout the United States, Western Europe, and Africa. In 1983, researchers in the United States and France described the virus that causes AIDS, now known as HIV, belonging to the group of viruses called retroviruses. While HIV infection is required to develop AIDS, the actual definition of AIDS is the development of a low CD4 cell count (<200 cells/mm3) or any one of a long list of complications of HIV infection ranging from a variety of so-called "opportunistic infections," cancers, neurologic symptoms, and wasting syndromes. AIDS • How is HIV spread (transmitted)? • HIV is present to variable degrees in the blood and genital secretions of virtually all individuals infected with HIV, regardless of whether or not they have symptoms. The spread of HIV can occur when these secretions come in contact with tissues such as those lining the vagina, anal area, mouth, eyes (the mucus membranes), or with a break in the skin, such as from a cut or puncture by a needle. The most common ways in which HIV is spreading throughout the world include sexual contact, sharing needles, and by transmission from infected mothers to their newborns during pregnancy, labor (the delivery process), or breastfeeding. (See the section below on treatment during pregnancy for a discussion on reducing the risk of transmission to the newborn.) • Sexual transmission of HIV has been described from men to men, men to women, women to men, and women to women through vaginal, anal, and oral sex. The best way to avoid sexual transmission is abstinence from sex until it is certain that both partners in a monogamous relationship are not HIV-infected. Because the HIV antibody test can take months to turn positive after infection occurs, both partners would need to test negative for at least 12 and up to 24 weeks after their last potential exposure to HIV. If abstinence is out of the question, the next best method is the use of latex barriers. This involves placing a condom on the penis as soon as an erection is achieved in order to avoid exposure to pre-ejaculatory and ejaculatory fluids that contain infectious HIV. For oral sex, condoms should be used for fellatio (oral contact with the penis) and latex barriers (dental dams) for cunnilingus (oral contact with the vaginal area). A dental dam is any piece of latex that prevents vaginal secretions from coming in direct contact with the mouth. Although such dams occasionally can be purchased, they are most often created by cutting a square piece of latex from a condom • The spread of HIV by exposure to infected blood usually results from sharing needles, as in those used for illicit drugs. HIV also can be spread by sharing needles for anabolic steroids to increase muscle, tattooing, and body piercing. To prevent the spread of HIV, as well as other diseases including hepatitis, needles should never be shared. At the beginning of the HIV epidemic, many individuals acquired HIV infection from blood transfusions or blood products, such as those used for hemophiliacs. Currently, however, because blood is tested for both antibodies to HIV and the actual virus before transfusion, the risk of acquiring HIV from a blood transfusion in the United States is extremely small and is considered insignificant. • There is little evidence that HIV can be transferred by casual exposure, as might occur in a household setting. For example, unless there are open sores or blood in the mouth, kissing is generally considered not to be a risk factor for transmitting HIV. This is because saliva, in contrast to genital secretions, has been shown to contain very little HIV. Still, theoretical risks are associated with the sharing of toothbrushes and shaving razors because they can cause bleeding, and blood can contain large amounts of HIV. Consequently, these items should not be shared with infected people. Similarly, without sexual exposure or direct contact with blood, there is little if any risk of HIV contagion in the workplace or classroom. Symptoms of AIDS • • • • • • • • • • • • The symptoms of HIV and AIDS vary, depending on the phase of infection. Primary infection The majority people infected by HIV develop a flu-like illness within a month or two after the virus enters the body. This illness, known as primary or acute HIV infection, may last for a few weeks. Possible symptoms include: Fever Muscle soreness Rash Headache Sore throat Mouth or genital ulcers Swollen lymph glands, mainly on the neck Joint pain Night sweats Diarrhea Prevention • To help prevent the spread of HIV, you should: • Use a new condom every time you have sex. If you don't know the HIV status of your partner, use a new condom every time you have anal or vaginal sex. Women can use a female condom. Use only water-based lubricants. Oil-based lubricants can weaken condoms and cause them to break. During oral sex use a condom, dental dam &madsh; a piece of medical-grade latex — or plastic wrap Prevention • Use a clean needle. If you use a needle to inject drugs, make sure it's sterile and don't share it. Take advantage of needle-exchange programs in your community and consider seeking help for your drug use. • Tell your sexual partners if you have HIV. It's important to tell anyone with whom you've had sex that you're HIV-positive. Your partners need to be tested and to receive medical care if they have the virus. They also need to know their HIV status so that they don't infect others • you're pregnant, get medical care right away. If you're HIV-positive, you may pass the infection to your baby. But if you receive treatment during pregnancy, you can cut your baby's risk by as much as two-thirds Treatment of AIDS • There is no cure for HIV/AIDS, but a variety of drugs can be used in combination to control the virus. Each of the classes of anti-HIV drugs blocks the virus in different ways. It's best to combine at least three drugs from two different classes to avoid creating strains of HIV that are immune to single drugs. Bioterrorism • livestock, or crops. The use of micro-organisms to cause disease is a growing concern for public health officials and agricultural bodies. The terrorist attacks on September 11, 2001 and the subsequent bioterrorist releases of anthrax have led to an increased awareness of workplaces as possible terrorist targets. • Anthrax Inhalation Skin contact Oral Consumption • Smallpox Anthrax Inhalation • Most serious form of anthrax causes death in 99% of the cases. Anthrax Skin • Causes infection when it comes in contact with skin. Blisters break and turn into black scabs Anthrax Oral Consumption • The least common method of spreading anthrax to humans. Smallpox • Smallpox is a serious and contagious disease due to a virus • Smallpox was once found throughout the world, causing illness and death wherever it occurred. It mainly affected children and young adults. Family members often infected each other. • Smallpox spreads easily from one person to another from saliva droplets. It may also be spread from bed sheets and clothing. It is most contagious during the first week of the infection. It may continue to be contagious until the scabs from the rash fall off Symptoms of Smallpox • Symptoms • Symptoms usually occur about 12 - 14 days after you have been infected with the virus. They may include: • Backache • Delirium • Diarrhea • Excessive bleeding • Fatigue • High fever • Malaise • Raised pink rash -- turns into sores that become crusty on day 8 or 9 • Severe headache • Vomiting Treatment of Smallpox • Treatment • If athe smallpox vaccine is given within 1-4 days after a person is exposed to the disease, it may prevent illness or make the illness less severe. Once symptoms have started, treatment is limited. • There is no drug specifically for treating smallpox. Sometimes antibiotics are given for infections that may occur in people who have smallpox. Taking antibodies against a disease similar to smallpox (vaccinia immune globulin) may help shorten the duration of the disease. • People who have been diagnosed with smallpox and everyone they have come into close contact with need to be isolated immediately. They need to receive the vaccine and be monitored. • Emergency measures would need to be taken immediately to protect the general population. Health officials would follow the recommended guidelines from the CDC and other federal and local health agencies