Download CURRICULUM VITAE Betsy Clement Herold, M.D. Office Address:

CURRICULUM VITAE
Betsy Clement Herold, M.D.
Office Address:
Albert Einstein College of Medicine
1300 Morris Park Avenue
Forchheimer 702
Bronx, NY 10461
Phone: (718) 430-2974
Fax: (718) 430-8627
Email: [email protected]
ACADEMIC APPOINTMENTS
6/2009Tenure, Albert Einstein College of Medicine, Yeshiva University
10/2007Professor of Pediatrics, Microbiology & Immunology, and Obstetrics &
Gynecology and Women’s Health
Vice Chair for Research Development, Dept. of Pediatrics
Albert Einstein College of Medicine
1/05-10/07
Professor with Tenure
Department of Pediatrics
Mount Sinai School of Medicine
1/06-10/07
Professor of Microbiology
Mount Sinai School of Medicine
3/02-10/07
Chief, Division of Pediatric Infectious Diseases
Mount Sinai School of Medicine
New York, NY
1/00-12/05
Associate Professor of Microbiology
Mount Sinai School of Medicine
New York, NY
7/98-12/04
Associate Professor of Pediatrics
Mount Sinai School of Medicine
New York, NY
7/92-6/98
Assistant Professor of Pediatrics and Virology
University of Chicago
Chicago, IL
HOSPITAL APPOINTMENTS
10/2007Pediatrics, Children’s Hospital at Montefiore
7/98-10/07
Pediatrics, Mount Sinai Medical School and Hospital
7/92-6/98
Assistant Professor in Pediatrics, The University of Chicago Children's Hospital
Chicago, Illinois
7/90-6/92
Clinical Associate (Track V): University of Chicago
7/85-6/90
Staff Physician: Children’s Memorial Hospital, Chicago, Illinois
EDUCATION
1974-1978
1978-1982
Brown University, Providence, RI
B.A., Biology
University of Pennsylvania Medical School, Philadelphia, PA, M.D.
April, 2010
Herold, Betsy Clement
POSTDOCTORAL TRAINING
7/90-6/92
Research Associate/Postdoctoral Fellow, Department of Microbiology/
Immunology, Northwestern University, Chicago, IL
7/87-6/90
Fellow, Pediatric Infectious Diseases, Children's Memorial Hospital, Chicago
7/86-6/87
Research Postdoctoral Fellow, Hagedorn Research Laboratory, Gentofte, Denmark
7/85-6/86
Chief Resident in Pediatrics, Children's Memorial Hospital, Chicago, IL
7/82-6/85
Internship and Residency in Pediatrics, Children's Memorial Hospital,
Northwestern University, Chicago, IL
CERTIFICATION
1983
National Board of Medical Examiners
1986
American Board of Pediatrics
1997-2004
Pediatric Infectious Diseases, American Board of Pediatrics
2004-2011
Recertification, Pediatric Infectious Diseases, American Board of Pediatrics
LICENSURE
1982
1998
Illinois - 036-067247
New York: 210077-1
HONORS
1978
1981
1982
1995
1995
1996
1997
2003
2007-2010
2007-2010
Sigma XI, Brown University
Alpha Omega Alpha Honor Medical Society, University of Pennsylvania
Henry and Jacob Lowenberg Prize in Pediatrics, University of Pennsylvania
Pediatric Infectious Disease Society Young Investigator Award
Infectious Disease Society of America Burroughs Wellcome Young Investigator Award
The U. of Chicago, Dept of Pediatrics, Outstanding Teacher Award
Society for Pediatric Research
American Pediatric Society
Office of AIDS Research Scientific Advisory Council
Pediatric Infectious Disease Society Council
OTHER PROFESSIONAL APPOINTMENTS
Professional Societies:
1997Society for Pediatric Research
2003American Pediatric Society
1993American Society of Microbiology
1998
Infectious Disease Society of America
1988
Pediatric Infectious Disease Society
Elected: Nominations and Awards Committee: 2005-2007
Council; 2007-2010
Chair, Membership Committee: 2008-10
Research Affairs Committee: 20102007
American Society of Transplantation
Infectious Disease Community of Practice
Editorial Boards
2010-2012
American Journal of Reproductive Immunology
Study Sections and NIH related activities:
1996-1998
Leukemia Research Foundation National Grant Review Committee
1999
Ad Hoc Member NIHNIAID STD Center Grants
2002
Ad Hoc Member NIH/NICCHD Special Study Section PO1 Review
2002
Ad Hoc Member, NIH/CIPRA Grant Review
2003
Ad Hoc Member, NIDCR Mucosa HIV RFA Study Section
2
April, 2010
2004
2004
2005
2005
2005
2006
2008
2009-10
Herold, Betsy Clement
NIAID SBIR/STTR Special Emphasis Panel
NIH Advisory Panel on Cytokines for Topical Microbicide Development
NIH, Office of AIDS Research, Invited Consultant: “Rationalizing Microbicide
Preclinical Assessment”, Washington, D.C.
Ad Hoc Member, NIH Oral Mucosal HIV RFA Study Section
Ad Hoc Member, NIH/NIAID ACE Study Section
NIAID Center for AIDS Research (CFAR) Study Section
Viral Pathogenesis Special Emphasis Panel, Chairperson (Jan. 8, 2008)
Highly Innovative Tactics to Interrupt Transmission of HIV,
Special Emphasis Panel
Other National and International Committees:
1997
International Herpes Virus Workshop Steering Committee
1997
International Herpes Virus Workshop Abstract Reviewer
1997
Co-chair Neonatal Infectious Diseases Session, SPR
1998
Reviewer, SPR abstracts; Section Neonatal Infectious Diseases
2001
NIAID Office of Aids Research, Invited Participant: Workshop on
Microbicide Research
2002
Moderator, Infectious Disease Session, SPR
2002
Convener: American Society of Virology: Viral Entry Session
2002
Infected Disease Society of America: Invited Panelist
2003-2006
SPR Student Research & House Officer Award Selection Committee
2004
Invited Consultant: Next Steps in Microbicide Development: Funders
Consultation, April 2004, Alliance for Microbicide Development and the Bill &
Melinda Gates Foundation, Washington, D.C.
2004
Moderator, AIDS Session, Infectious Disease Society of America 42nd Annual
Meeting, October, 2004, Boston, MA
2004
Site Review; Microbiology Laboratories
St. Christopher’s Hospital for Children, Phila., PA
2005-2006
American Academy of Pediatrics
Faculty Member, PREP: The Course
2005
HIV Management 2005: the New York Course, Invited Faculty
2005
Reviewer, SPR Abstracts; Section: Infectious Diseases
2005
Microbicides 2006: Scientific Advisory Committee
2005International Partnership for Microbicides Advisory Board
2006PIDS Taskforce: “How do ID Sections Pay for Themselves”
2006
“Development of Standardized Microbicide Toxicity Tables for Clinical Trials”
Invited participant
2007NIH, Microbicides Scientific Advisory Committee
2008
HIV Management 2009: the New York Course, Invited Faculty
2008
UCSF Advances and Controversies in Clinical Pediatrics, Invited Faculty
2008-current Chair, New York Organ Donor Network Infectious Disease Workgroup
2006-09
International Partnership for Microbicides (IPM), Advisory Committee
2008Global Campaign for Microbicides, Advisory Panel
2010
Microbicides 2010 Scientific Advisory Committee
MAJOR INSTITUTIONAL COMMITTEE ASSIGNMENTS:
University of Chicago:
1993-1998
Member, Committee on Virology
1994-1998
Institutional Biosafety Committee
1994-1998
Committee on Virology, Graduate Student Admissions Committee
1994-1998
Committee on Virology, Graduate Student Thesis (6 students)
3
April, 2010
Herold, Betsy Clement
1995-1998
1995-1998
1995-1998
1996-1998
1997-1998
Director, Pediatric Infectious Diseases Fellowship Training Program
Pediatric Representative, Committee on Infection Control and Epidemiology
Residency Selection Committee
Nephrology Search Committee
Committee to Review Developmental Biology Program
Mount Sinai School of Medicine
1998-present Infectious Diseases/Clinical Microbiology Coordinating Committee
1999-2003
Institutional Biosafety Committee
1999-2001
Department of Pediatrics Search Committee for Hematology-Oncology
Division Head
1999-2001
Department of Microbiology Search Committee for Virologist
1999-2007
Pediatric Research Day Steering Committee
1999-2007
Internship Applicant Committee
2000-2007
MSTP and Graduate School Admissions Interviewer
2000-2007
Pediatric Residency Advisory Board
2000-2003
Ph.D. Thesis Advisory Committee, Laura Gillim
2000-2007
General Clinical Research Center Advisory Committee
2002-2007
Morbidity and Mortality Committee
2002-2007
Infection Control Committee; Bioterrorism subcommittee
2002-2007
Pharmacy and Therapeutics Committee
2003-2004
Bioterrorism Preparedness Coordinator
2003-2007
Search Committee, Medicine/Pediatrics Program Director
2004-2005
Departmental Pediatric Fellowship Core Curriculum Committee, Director
2004-2005
Clinical Practice and Utilization - Antifungals Review, Chair
2004-2007
Dean’s Lecture Ad Hoc Committee
2004-2006
Pediatric Research Day; Director of Steering Committee
2005-2006
Search Committee/ Chair Dept of Ophthomology
2006-2007
Chair, Search Committee, Chief, Division of Hematology-Oncology
Division Chief
Albert Einstein College of Medicine/Montefiore Medical Center
2008Pediatric Departmental Internal Grant Award Committee-Chair
2008Pediatric Research Day Committee-Chair
2008Transplantation Translational Research Working Group
2008STD Prevention Research Working Group-Director
2008CERC Search Committee
2009Committee on Appointments and Promotions to Professor
2010
Tenure Committee
REVIEWER:
Journal of General Virology
Journal of Infectious Diseases
Journal of Virology
PLoSOne
Pediatric Infectious Disease Journal
Journal of Pediatrics
Pediatrics
JAMA
Antiviral Research
Virology
AIDS
JCI
Pediatric Transplantation
4
April, 2010
Herold, Betsy Clement
Nature Mucosal Immunology
PLoS Pathogen
TRAINING RECORD
Name
Susan I Gerber, M.D
Level of
Learner
Fellow
Role in Training
Lilly H Immergluck,M.D.
Fellow
Veronica Mas Casullo
Fellow
Mentor: American Social
Health Association
Postdoctoral Research
Fellow
1999-2001
2005-present
Instructor, Mount
Sinai School of
Medicine
Natalia Cheshenko
Post-doc
Mentor
2000-present
Sara Sinha, M.D.
Medical
student
Mentor: National
Student Research Forum
Honoree;
1999-2003
Assistant
Professor,
AECOM
Fellow (Ob-Gyn)
Yale
Minnie John, M.D.
Fellow
NIH T32 Mentor
Program Director (PID)
2002-2004
Ana Tuyama, M.D.
Postdoc
Mentor
2002-2005
Cindy Goldberg, M.D.
Fellow
Mentor
Program Director (PID)
2002-2005
Mount Kisco
Pediatrics
Maria Josefina Carlucci
Postdoc
Mentor
2003-2006
Rebecca Madan, M.D.
Fellow
NIH T32 Mentor
Program Director (PID)
7/04-7/07
Universidad de
Buenos Aires
Assist Prof.
AECOM
Esra Fakioglu, M.D.
Fellow
Mentor
7/05-7/07
Assist Prof,
AECOM
Sarju Patel
Mentor
8/04-2006
Vikas Shende, PhD
Pedro Mesquita, PhD
Janie Trepanier, PhD
Gail Shust, M.D.
Manisha Patel, M.D.
Martha Stefanidu, PhD
Medical
student
Postdoc
Postdoc
Postdoc
Fellow
Fellow
Postdoc
Mentor
Mentor
Mentor
Mentor
NIH T32 Mentor
Mentor
2006-2008
2007-present
2007-present
2007-2009
2008-present
2009-
Doris Duke Fellow
Clinical Research
India
Jenny George, M.D.
Faculty
Mentor/CRTP
2009-
Mentor, NIH Physician
Scientist Award
Mentor: Pediatric Dept
Chairmen Pediatric
Career Physician
Scientist Award
5
Inclusive
Dates
1992-1996
1994-1996
Current Position
Chicago Dept of
Public Health
Assistant Professor
U. of Illinois
Faculty, Long
Island College
Hospital
Resident MSSM
Faculty, MSSM
April, 2010
Herold, Betsy Clement
TEACHING ACTIVITIES
2010
2009200820072000-2006
2005-2007
2003
2003
1999-2007
1994-1998
1994-1997
Graduate Immunology, Course Lecturer
Graduate Virology, Course Lecturer
Microbiology Medical School Course Lecturer, AECOM
Small Group Leader, Immunology, AECOM
Course Director: Integrative Core Block, Year 1, MSSM
Lecturer & Small Group Session Leader, PMHD, Year 1 MSSM
Lecturer, Advanced Virology, MSSM
Lecturer, Public Health and Epidemiology, Columbia University
Lecturer, MDT Infectious Diseases Module, MSSM
Lecturer, Animal Virology, spring quarter, U. of Chicago
Lecturer, Medical Microbiology, U. of Chicago
GRADUATE STUDENT THESIS ADVISORY COMMITTEES:
1994-1997
William Ogle, Ph.D.
University of Chicago
1996-2000
Glenn Randall, Ph. D.
University of Chicago
1999-2002
Laura Gillim, Ph.D.
Mount Sinai
1999-2003
Jesus Vargas, Ph.D.
Mount Sinai
1999-2002
Beverly Barham, Ph.D.
Southern Illinois University
2003-2008
Jamie Potter
Southern Illinois University
2006
Laura Glaser
Mount Sinai
GRANT SUPPORT
Current Grants:
U19AI076980
9/10/09 – 8/31/13
Intravaginal Ring Delivery of Safe & Effective Microbicides to Prevent HIV & HSV
Role: PI and Project Leader, Project 1
AI061679 RO1
Role of calcium signaling in HSV-2 invasion
Role: PI
2/15/05-1/31/11
AI065309 RO1
6/15/05-5/31/2015
Impact of HSV-2 on female genital tract mucosal immunity & HIV infection
Role: PI
R21AI079763
Novel Mucosal Models Predictive of Microbicide Safety
Role: PI
09/01/08-8/31/10
1UO1 AI068633
3/1/06-2/28/13
Microbicides Trial Leadership Network
PI: Sharon Hillier, Magee-Women’s Health Corporation
Role: Science Development Subcommittee Chair: Safety Biomarkers
U19 AI70202 (PI: B Ramratnam, Brown U.)
siRNA as Vaginal Microbicides
Role: Project Leader (P2):
“Novel siRNA Microbicides to Prevent and Treat HSV
6
9/30/06-8/31/10
April, 2010
Herold, Betsy Clement
UO1 AI 69551-01 (PI: Marla Keller)
Microbicide effects on efficacy, safety, innate immunity
PI: Marla Keller
Role: Co-investigator
9/1/05-2/28/11
RO1AI076169
Antiviral lectins as microbicides
PI Kenneth Palmer, U. of Louisville
Role: Co-investigator
04/15/08-3/31/12
U01AI035004
8/1/93-12/31//2012
Womens Interagency HIV Study
Role: Co-I
Supplementary study PI
Mucosal immunity in the genital tract in HIV Infected & uninfected women
R21AI 08341801
Innate resistance to mucosal HSV infection in humans
PI: Christine Posavad, U. of Washington
Role: Co-investigator
R01 PA07356
Expanded Phase II Trial of carraguard for prevention of HPV
PI: Mark Einstein (Albert Einstein College of Medicine)
Role: Co-I
7/23/09-6/30/11
6/1/10-3/31/15
R41AI091246
Cotton Rat: Animal model predictive of clinical responsiveness
to HSV vaccines
7/0110-6/30/12
CONRAD: Evaluation of Safety of Cellulose Sulfate
2008-2010
International Partnership for Microbicides
“Ex vivo Assessment of Pharmacodynamics of Dapivirine:
2009-2011
Completed Grants:
1986-1987
1992-1994
1993-1994
Role of Immune Complexes in Type 1 Diabetes
Juvenile Diabetes Foundation Research Grant
Role: PI
Heparan Sulfate Receptors for HSV
Children’s Research Foundation Award, The University of Chicago
Role: PI
Entry for HSV-1 an HSV-2
Louis H. Block Fund for Basic Research and Advanced Study Award
University of Chicago
7
April, 2010
Herold, Betsy Clement
1989-1994
1994-1997
1995-1997
1995-1999
1995-2000
1997-2000
1995-2005
1999-2004
2000-2005
2001-2006
2003-2007
2006-2007
2006-2008
2002-2007
2006-2009
Role: PI
Role of Herpes Virus Complement Binding Proteins
Physician Scientist Award, NIAID, NIH (K11 AI00945-06)
Role: PI
Viral Receptors for HSV-1 and HSV-2
American Cancer Society Jr. Faculty Award
Role: PI
Heparan Sulfate Receptors for HSV-1 and HSV-2
Ronald McDonald Foundation Research Grant
Role: PI
Defining the pathway of HSV Invasion
Infectious Disease Society of America Burroughs Wellcome Young
Investigator Award in Virology
Role: PI
Glycosaminoglycan receptors for HSV-1 and HSV-2
R29AI 36318
Role: PI
Host and virus factors regulating herpes simplex virus entry
American Cancer Society Research Project Grant
PI-R. Roller, University of Iowa
Role: Co-investigator
Topical microbicides for prevention of STD’s/HIV
2-PO1 AI37940 (PI: L. Stanberry,UT, Galveston)
Role: Project Leader, Project 2
Deans’ Research Award (PI Betsy Herold)
Development of the Adolescent Health Center as Strategic Site for
Multidisciplinary Research for the Prevention and Treatment of STD
NIH T-32AI 07623 (PI: M. Klotman)
Physician Scientist Research Training Pathogenesis of Viral Diseases
Role: Co-PI
PO1-HD41763-01 (PI: Mary Klotman)
Development of dimandelic acid as a topical microbicide for HIV & HSV
Role: Project leader for Project 2
Co-investigator for Project 4
U54 AI057158 (PI: WI Lipkin, Columbia U.)
Northeast Biodefense Center Career Development Award
Role: Mentor CDA-2
Prospective comparative study of the humoral & CMI responses to the
trivalent subviron influenza vaccine in pediatric liver transplant recipients
Astrellas Pharmaceuticals
Retrospective Study of Fungal Infections in Transplantation Recipients
R41AI069659-01NIH/STTR
PI: Michael Oldham, YASO Biotechnology Inc.
Development of SAMMA based vaginal microbicides
Role: Subsite PI
CONRAD, Eastern Virginia Medical School
Evaluation of candidate topical microbicides for anti-HSV activity
Role: PI
R41AI071451-01 NIH/STTR PI: Greg Prince, Virion Systems
Novel Model to Predict Safety and Efficacy of Microbicides
Role: Co-PI
8
April, 2010
Herold, Betsy Clement
2002-2009
2009
PO1HD43733/ 8U19 AI077549 (PI: Betsy Herold)
Multitargeted Microbicide Combinations to Block HIV
R43AI081552-01 (PI: Thomas Smith)
Sustained release acyclovir for prophylaxis of genital herpes
Role; Co-investigator
PUBLICATIONS:
PEER-REVIEWED PUBLICATIONS:
1)
Herold BC, Davis AT, Arroyave C, et al. Cryoprecipitates in Kawasaki Syndrome: Association
with coronary artery aneurysms. Pediatric Infectious Diseases, 7:255-258, 1988.
2)
Herold BC and Shulman ST. Poststreptococcal arthritis. Pediatric Infectious Diseases, 7: 682,
1988.
3)
Arditi M, Herold BC, Yogev R. Cefuroxime Failure in Haemophilus Influenzae Meningitis: Case
report and review of the literature. Pediatrics, 84: 132-135, 1989.
4)
Herold BC, WuDunn D, Soltys N and Spear PG. Glycoprotein C of herpes simplex virus type 1
plays a principal role in the adsorption of virus to cells in infectivity. Journal of Virology, 65:10901098, 1991.
5)
Spear PG, Shieh M-T, Herold BC, WuDunn D, and Koshy TI: Heparan sulfate
glycosaminoglycans as primary cell surface receptors for herpes simplex virus. Advances in
Experimental Medicine and Biology 313:341-353, 1992.
6)
Herold BC, Visalli R, Susmarski N, Brandt C, and Spear PG. Glycoprotein C (gC)-independent
binding of herpes simplex virus to cells requires cell surface heparan sulfate and virion
glycoprotein B (gB). J. of Gen Virol, 75: 1211-1222, 1994.
7)
Herold BC, Spear PG. Neomycin differentiates gC-dependent and gB-dependent interactions
with heparan sulfate proteoglycans and inhibits subsequent steps in herpes simplex virus
infectivity. Virology, 203: 166-171, 1994.
8)
Herold BC, Gerber S, Polonsky T, Belval BJ, Shaklee PN, Holme K. Identification of structural
features of heparin required for inhibition of herpes simplex virus type 1 binding. Virology, 206:
1108-1116, 1995.
9)
Gerber SI, Belval BJ, and Herold BC. Differences in the role of glycoprotein C of HSV-1 and
HSV-2 in viral binding may contribute to serotype differences in cell tropism. Virology, 214: 2939, 1995
10)
Herold BC, Gerber SI, Belval BJ, Siston A, and Shulman N. Differences in the susceptibility of
HSV-1 and HSV-2 to modified heparin compounds suggest serotype differences in viral entry. J.
Virol., 70: 3461-3469, 1996
11)
Herold BC, Sullivan C, Grayhack JJ, Dorning M, Daum RS. Toxic shock syndrome complicating
orthopedic manipulations of the bone. J. Bone and Joint Surgery, 78A: 903-906, 1996.
12)
Immergluck LC, Ben-Ami T, and Herold BC. Thymic Abscess Caused by Methicillin-Resistant
Staphylococcus Aureus. Pediatric Infectious Diseases, 15:96-97, 1996.
9
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Herold, Betsy Clement
13)
Zahraa J, Herold BC, Abrahams C, Johnson DJ. Bronchiolitis obliterans: An unusual lung
finding in a child with acquired immunodeficiency syndrome. Pediatric Infectious Diseases, 15:
448-451, 1996.
14)
Zahraa J, Johnson DJ, Lim-Dunham J, and Herold BC. Unusual features of osteo-articular
tuberculosis. J Pediatrics, 129: 597-602, 1996.
15)
Seferian E, and Herold BC. Polymicrobial bacteremia: a presentation of Munchäusen
Syndrome-by-Proxy. Clinical Pediatrics, July: 419-422, 1997.
16)
Roller RJ and Herold BC. Characterization of a BHK(TK-) cell clone resistant to postattachment entry by herpes simplex viruses 1 and 2. J. Virology, 71: 5805-5813, 1997.
17)
Herold BC, Siston A, Bremer J, Kirkpatrick R, Fugedi P, Peto C, Wilbanks G, and Cooper M.
Sulfated carbohydrate compounds prevent microbial adherence by sexually transmitted disease
pathogens. Antimicrobial Agents and Chemotherapy, 41: 2776-2780, 1997.
18)
Herold BC, Immergluck LC, Maranan M, Lauderdale DS, Gaskin R, Boyle-Vavra S, and Daum
RS. Emergence of methicillin-resistant Staphylococcus aureus (MRSA) as a pediatric
community-acquired pathogen. JAMA, 279:593-599, 1998.
19)
Immergluck LC, Domowicz MS, Schwartz NB, and Herold BC. Viral and cellular requirements
for entry of herpes simplex virus type 1 into primary neuronal cells. J. Gen. Virology, 79:549559, 1998.
20)
Herold BC, Kirkpatrick R, Marcellino D, Travelstead A, Pilipenko V, Krasa H, Bremer J, Dong LJ,
and Cooper MD. Bile salts: natural detergents for the prevention of sexually transmitted
diseases. Antimicrobial Agents and Chemotherapy, 43: 745-51, 1999.
21)
Qie L, Marcellino D, and Herold BC. Participation of tyrosine phosphorylation in herpes simplex
viral entry. Virology 256: 220-27, 1999.
22)
Herold BC, Bourne N, Marcellino D, Kirkpatrick R, Strauss D, Zanenveld LJD, Waller D,
Anderson R, Chany C, Stanberry LR, and Cooper MD. Poly(sodium 4-styrenesulfonate): An
effective candidate topical antimicrobial for the prevention of sexually transmitted diseases. J.
Inf. Dis. 181: 770-3, 2000.
23)
Oram RJ, Marcellino D, Strauss D, Gustafson E, Talarico CL, Root AK, Thompson K, Fingeroth
JD, Crumpacker C, and Herold BC. Characterization of an acyclovir resistant herpes simplex
type 2 strain isolated from a premature neonate. J. Inf. Dis. 181: (4) 1458-61, 2000.
24)
Hendrickson BA, Guo J, Brown I, Dennis K, Marcellino D, Hetzel J, and Herold BC. Decreased
vaginal disease and mortality in J chain-deficient mice following herpes simplex type 2 genital
infection. Virology, 271: 155-62, 2000.
25)
Anderson RA, Feathergill K, Diao X, Cooper M, Kirkpatrick R, Spear P, Waller DP, Chany C,
Doncel GF, Herold B, Zaneveld LJD. Evaluation of poly(styrene-4-sulfonate) as a preventative
agent for conception and sexually transmitted diseases. Journal of Andrology, 21: 862-75, 2000.
26)
Mas Casullo V, Bottone E, Herold BC. Peptostreptococcus asaccharolyticus Renal Abscess: A
rare cause of fever of unknown origin. Pediatrics, 107: E11, 2001.
10
April, 2010
Herold, Betsy Clement
27)
Zaneveld LJD, Waller DP, Anderson RA, Chany C, Rencher WF, Feathergill K, Diao X-H,
Doncel GF, Herold B, and Cooper M. Efficacy and safety of a new vaginal contraceptive
antimicrobial formulation containing high molecular weight poly(sodium 4-styrenesulfonate).
Biology Reprod, 66: 886-894, 2002.
28)
Anderson RA, Feathergill KA, Diao X-H, Cooper MD, Kirkpatrick R, Herold BC, Doncel GF,
Chany CJ, Waller DP, Rencher WF, and Zaneveld LJD. Preclinical evaluation of sodium
cellulose sulfate (UshercellTM) as a contraceptive antimicrobial agent. J. Andrology 23: 426-38,
2002.
29)
Zaneveld LJD, Anderson RA, Diao X-H, Walker DP, Chany C, Feathergill K, Doncel G, Cooper
MD, and Herold BC. A new antimicrobial contraceptive agent for vaginal prophylactic use:
mandelic acid condensation polymer (SAMMA). Fertility & Sterility 78: 1107-15, 2002.
30)
Cheshenko N and Herold BC. Glycoprotein B plays key role in mediating HSV-2 binding and is
essential for entry and cell-cell spread. J Gen Vir 83: 2247-52, 2002.
31)
Herold BC, Scordi-Bello I, Cheshenko N, Marcellino D, Dzuzelewski M, Francois F, Morin R,
Mas Casullo V, Anderson RA, Chaney C, Waller DP, Zaneveld LJD, and Klotman ME. Mandelic
Acid Condensation Polymer: Novel Candidate Microbicide for Prevention of Human
Immunodeficiency Virus and Herpes Simplex Virus Entry. J. Virology 76: 11236-44, 2002.
32)
Herold BC, Marcellino D, Marcelin G, Burrow C, Wilson P, and Satlin LM. Herpes simplex virus:
a model vector system for gene therapy for renal disease. Kidney International, 61: S1: 3-8,
2002.
33)
Kaufman SS, Chatterjee NK, Fuschino ME, Magid MS, Gordon RE, Morse DL, Herold BC,
LeLeiko NS, Tschernia A, Florman SS, Gondolesi GE, Fishbein TM. Calicivirus Enteritis in an
Intestinal Transplant Recipient. Am J Transplant 6; 764-68, 2003.
34)
Donnelly M, Herold BC, Jenkins S, and Daum RS. Obstacles to the eradication of invasive
haemophilus influenzae type b: three illustrative cases. Pediatrics 112; 1465-6, 2003.
35)
Sinha S, Cheshenko N, Lehrer RI, Herold BC. NP-1, a rabbit a-defensin, prevents the entry and
intercellular spread of HSV-2. Antimicrobial Agents & Chemo 47: 494-500, 2003.
36)
Cheshenko N, Del Rosario, B, Woda C, Marcellino D, Satlin L, and Herold BC. Calcium
signaling pathways are required for herpes simplex virus entry. J Cell Biology 163; 283-93;
2003.
37)
Pinchoff RS, Kaufman S, Magid MS, Erdman DD, Mendelson M, Gondolesi GE, Fishbein TM,
and Herold BC. Adenovirus: Common pathogen in pediatric small bowel transplantation
recipients. Transplantation, 76. 183-9; 2003.
38)
Keller MJ, Klotman ME, Herold BC. Topical microbicides for the prevention of HIV and HSV.
AJRI 49: 279-84, 2003.
39)
Keller MJ, Klotman ME, Herold BC. Rigorous pre-clinical evaluation of topical microbicides
to prevent human immunodeficiency virus. J Antimicrob Chemother., 51: 1099-102;
2003.
11
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Herold, Betsy Clement
40)
Yasin B, Wang W, Pang M, Cheshenko N, Hong T, Waring A, Herold BC, Wagar E, and Lehrer,
RI.
and entry. J Virology 78; 5147-56, 2004.
41)
Cheshenko N, Keller, MJ, MasCasullo V, Jarvis, G, Cheng, H., John, M, Li, J-H., Hogarty, K.,
Anderson RA, Waller, DP, Zaneveld L, Profy, AT., Klotman ME, and Herold BC. Sulfonated
polymers bind HSV glycoprotein B and prevent viral entry and cell-cell spread. AAC 48; 202536, 2004.
42)
Jing, B., Janout, V., Herold, BC, Klotman, ME, Heald, T., and Regen, S. Persulfated molecular
umbrellas as anti-HIV and anti-HSV agents. J Am Chem Soc; 126(49):15930-1, 2004.
43)
Campbell, AL and Herold, BC. Preemptive and Prophylactic Strategies to Prevent CMV in
Pediatric Liver Transplantation Recipients. Pediatric Transplantation, 8: 619-27; 2004.
44)
Keller, MJ, Tuyama, A., Carlucci, MJ, and Herold, B.C. Topical microbicides for the prevention
of genital herpes infection. J Antimicrob Chemother, 55: 420-3, 2005.
45)
Scordi-Bello, IQ, Mosoian, A, He, C, Chen, Y, Jarvis, GA, Keller, MJ, Hogarty, K, Waller, DP,
Profy, AT, Herold, BC and Klotman, ME. Candidate sulfonated and sulfated topical
microbicides: comparison of anti-HIV activity and mechanism of action. Antimicrobial Agents &
Chemo, 49: 3607-15, 2005.
46)
Cheshenko, N., Liu, W., Satlin, LM, and Herold, BC. Focal adhesion kinase plays a pivotal role
in HSV-2 invasion. J Biol Chem, 280: 31116-25, 2005.
47)
Campbell, AL and Herold, BC. Immunization of pediatric solid-organ transplantation candidates.
Pediatric Transplantation, 9; 652-61. 2005.
48)
John, M, Keller, MJ, Cheshenko, N, Hogarty, K, Kasowitz, A, Herold, J, Wallenstein, S, Carlucci,
M, Tuyama, A, Lehrer, RI, Klotman, ME and Herold BC. Cervicovaginal secretions convey
innate immunity to genital herpes. Journal of Infectious Diseases, 192: 1731-40, 2005.
49)
Yim, KC, Carroll, CJ, Tuyama, A, Cheshenko, N, Carlucci, MJ, Porter, DD, Prince, GA, and
Herold, BC. Cotton rat provides a novel model to study genital herpes infection and to evaluate
preventative strategies. J Virology 79: 14632-9, 2005.
50)
MasCasullo, V, Fam, E, Keller, MJ and Herold BC. Role of Mucosal Immunity in Preventing
Genital Herpes Infection. Viral Immunology 18: 595-606; 2005.
51)
John, M., Gondolesi G, Herold, BC, Kaufman, S, Fishbein, T. and Posada, R. Impact of
surveillance stool culture guided selection of antibiotics in the management of small bowel
transplantation recipients. Pediatric Transplantation, 10; 198-204, 2006.
52)
Keller, MJ, Zerhouni-Layachi, B, Cheshenko N,John, M., Hogarty, K, Kasowtz, A., Goldberg, C.,
Profy, A.T., Klotman, ME and Herold, BC. PRO 2000/5 gel prevents HIV and HSV infection
following vaginal application: a double-blind, placebo controlled trial. JID 193:27-35, 2006.
53)
Campbell, AL, Goldberg, CL, Magid, M, Kaufman, S and Herold, BC. First case of
toxoplasmosis following SBT and systematic review of tissue-invasive toxoplasmosis following
non-cardiac solid organ transplantation. Transplantation 81: 408-17, 2006.
12
April, 2010
Herold, Betsy Clement
54)
Kasowitz, AR, McCusker, M, Cour-Doniger, P, Neal, WP, Indyk, D, Burk, RD, Jenkins, S. Ricker
VI, and Herold, BC. Stage of change behavioral assessment tool fails to predict the prevalence
of Chlamydia in an urban adolescent health clinic. J Pediatr Adolesc Gynecol. 19(4):277-83,
2006
55)
Tuyama, ACG, Cheshenko, N Carlucci, MJ, Li, J-H, Goldberg, CL,Waller, DP, Anderson RA
Profy AT, Klotman ME, Keller, MJ and Herold, BC. An acid-buffering gel inactivates HSV and
prevents genital herpes in a murine model. JID 194(6):795-803. 2006
56)
Fakioglu, E, Queenan, AM, Bush, K, Jenkins, SG, and Herold, BC. Amp C beta-lactamaseproducing Escherichia coli in neonatal meningitis: diagnostic and therapeutic challenge. J
Perinatol 26(8):515-7, 2006.
57)
Galen, B, Cheshenko, N., Tuyama, A., Ramratnam, B., and Herold, BC. Access to Nectin
Favors HSV Infection at the Apical Surface of Polarized Human Epithelial Cells. J Virol,
80(24):12209-18, 2006.
58)
Keller, MJ and Herold, BC. Impact of Microbicides and Sexually Transmitted Infections on
Mucosal Immunity in the Female Genital Tract. AJRI 56(5-6):356-63, 2006
59)
Hazrati, E, Galen, B., Lu, W, Wang, W, Ouyang, Y, Keller, MJ, Lehrer, RI, and Herold, BC.
Human Alpha- and Beta-Defensins Block Multiple Steps in HSV Infection. The Journal of
Immunology 177: 8658–8666, 2006.
60)
Kerkar N, Cohen S, Dugan C, Morotti RA, Phelps RG, Herold B, Shneider B, and Emre S.
Bullous pemphigoid after liver transplantation for liver failure. Liver Transpl. 12(11):1705-1710,
2006.
61)
Madan, R, Keller, MJ, and Herold BC. Prioritizing Prevention of HIV and STI: First-generation
vaginal microbicides. Curr Opin Infect Dis, 19: 49-54; 2006.
62)
Keller, MJ, Guzman, E., Hazrati, E., Kasowitz, A, Cheshenko, N, Wallenstein,S, Patel, S., Cole,
AL,. Cole, AM, Profy, AT, Wira, CR, Hogarty, K, and Herold, BC. PRO 2000 Elicits a Decline in
Genital Tract Immune Mediators without Compromising Intrinsic Antimicrobial Activity. AIDS, 21:
467-76, 2007.
63)
Galen, BT, Martin, AP, Hasrateean, E, Garin, A, Guzman, E, Wilson, SS, Porter, DD, Lira, SA,
Keller, MR and Herold, BC. A Comprehensive Murine Model to Evaluate Topical Vaginal
Microbicides: Mucosal Inflammation and Susceptibility to Genital Herpes as Surrogate Markers
of Safety. JID, 195(9):1332-9, 2007.
64)
Madan, RP, Mesquita, PMM, Cheshenko, N, Jing, B, Shende, V, Guzman, E, Heald, T, Keller,
MJ, Regen, S, Shattock, RJ and Herold, BC. Molecular Umbrellas: a Novel Class of Candidate
Topical Microbicides to Prevent HIV and HSV. J Virology, 81(14): 7636-46, 2007.
65)
Cheshenko, N, Liu, W, Satlin, LM, and Herold, BC. Multiple Receptor Interactions Trigger
Release of Membrane and Intracellular Calcium Stores Critical for HSV Entry/ Molecular Biology
of the Cell 18(8): 3119-30, 2007.
66)
Patel, S., Hazrati, E, Cheshenko, N, Galen, B, Yang, H, Guzman, E, Wang, R, Herold, BC and
Keller, MJ. Seminal Plasma Reduces the Effectiveness of Topical Polyanionic Microbicides, JID,
196(9):1394-402, 2007.
13
April, 2010
Herold, Betsy Clement
67)
Hogarty, K, Kasowitz, A, Herold, BC and Keller, MJ. Assessment of Adherence to Product
Dosing in a Pilot Microbicide Study. Sexually Transmitted Diseases. 34(12):1000-3, 2007
68)
Guzman, EM, Natalia Cheshenko, Vikas Shende, Marla J. Keller , Nathalie Goyette, Jean-Marc
Juteau, Guy Boivin, Andrew Vaillant, and Betsy C. Herold. Amphipathic DNA Polymers are
Candidate Vaginal Microbicides and Block HSV Binding, Entry and Viral Gene Expression.
Antiviral Therapy, 12: 1147-1156, 2007
69)
Madan, RP, Tan, M, Fernandez-Sesma, A, Moran, T, Emre, S, Campbell, A and Herold, BC. A
Prospective, Comparative Study of the Immune Response to Inactivated Influenza Vaccine in
Pediatric Liver Transplant Recipients and their Healthy Siblings. Clin Inf Dis, 46: 712-8, 2008.
70)
Khine, H, Mayers, M, Avner, JR, Fox, A, Herold, BC, and Goldman D. Associations between
HSV-1 infection and idiopathic unilateral facial paralysis in children and adolescents, PIDJ, 27:
468-9, 2008.
71)
Fichorova, Raina; Richardson-Harman, Nicola; Alfano, Massimo; Belec, Laurent; Carbonneil,
Cedric; Chen, Silvia; Cosentino, Lisa; Curtis, Kelly; Dezzutti, Charlene; Donoval, Betty; Doncel,
Gustavo; Donaghay, Melissa; Grivel, Jean-Charles; Guzman, Esmeralda; Hayes, Madeleine;
Herold, Betsy; Hillier, Sharon; Lackman-Smith, Carol; Landay, Alan; Margolis, Leonid; Mayer,
Kenneth; Pasicznyk, Jenna-Malia; Pallansch-Cokonis, Melanie; Poli, Guido; Reichelderfer,
Patricia; Roberts, Paula; Rodriguez, Irma; Saidi, Hela; Sassi, Rosaria Rita; Shattock, Robin;
Cummins, James. Biological and technical variables affecting immunoassay recovery of
cytokines from serum and simulated vaginal fluid- a multicenter study. Analytical Chemistry, 80:
4741-51, 2008.
72)
Feng T, Ye F, Wu J, Jiang S, Coolbaugh J, Shneider B, Herold B, Emre S, Zhang DY. The
effect of EBV sequence variation on the performance of a Roche real-time Lightcycler PCR
assay. J Clin Microbiol. 46:2463-5, 2008.
73)
Mesquita, PMM, Wilson, S, Manlowe, P, Fischetti, L, Keller, MJ, Herold, BC and Shattock RJ.
Candidate Microbicide PPCM Blocks HIV-1 Infection in Cell and Tissue Cultures
and Prevents Genital Herpes in a Murine Model. J Virol, 82: 6576-84, 2008.
74)
Fakioglu, E, Wilson, SS, Mesquito, P, Cheshenko, N, Blaho, J and Herold, BC. Herpes
Simplex Virus Down-Regulates Secretory Leukocyte Protease Inhibitor: A Novel Immune
Evasion Mechanism. J. Virol, 82(19):9337-44, 2008.
75)
Keller, MJ and Herold, BC. Understanding Basic Mechanisms and Optimizing Assays to
Evaluate the Efficacy of Vaginal Microbicides. Sexually Transmitted Diseases, 36: S92-5, 2009.
76)
Madan, R, Campbell, AL, Shust, G, Kahn, AH, Wistinghausen, B, Posada, R, Kerkar, N,
Shneider, BL, Emre, S and Herold, BC. A Hybrid Strategy for Prevention of Cytomegalovirus
and Epstein Barr Virus Related Complications in Pediatric Liver Transplant Recipients.
Transplantation,87(9):1318-24, 2009.
77)
Mesquita, PMM, Cheshenko, N, Wilson, SS, Mhatre, M, Guzman, E, Fakioglu, E, Keller, MJ, and
Herold, BC. Disruption of tight junctions by cellulose sulfate facilitates HIV infection: Model of
microbicide safety. J Infec Dis, 200: 599-608, 2009.
78)
Wilson, SS, Fakioglu, E, Herold BC Novel Approaches in Fighting Herpes Simplex Virus
Infections. Expert Review of Anti-infective Therapy, 7 (5): 559-568, 2009.
14
April, 2010
Herold, Betsy Clement
79)
Wilson, SS, Cheshenko, N, Fakioglu, E, Mesquita, PMM, Keller, MJ, and Herold, B.C.
Susceptibility to genital herpes as a biomarker predictive of increased HIV risk: expansion of a
murine model of microbicide safety. Antiviral Therapy, 14(8): 1113-24, 2009.
80)
Kerkar, N, Morotti, RA, Madan, R, Shneider, B, Herold, BC, Dugan, C, Miloh, T, Karabicak, I,
Strauchen, JA, and Emre, S. The changing face of post transplant lymphoproliferative disease in
the era of molecular EBV monitoring. Pediatric Transplantation, 2010.
81)
Shust, GF, Cho, S., Kim, M, Madan, RP, Guzman, EM, Pollack, M, Epstein, J, Cohen, HW,
Keller, JR, and Herold BC. Female genital tract secretions inhibit HSV infection: correlation
with soluble mucosal immune mediators and impact of hormonal contraception. Am J Reprodu
Immunol 63: 110-9, 2010.
82)
Keller MJ, Mesquita PM, Torres NM, Cho S, Shust G, Madan RP, Cohen HW, Petrie J, Ford T,
Soto-Torres L, Profy AT, Herold BC. Postcoital bioavailability and antiviral activity of 0.5% PRO
2000 gel: implications for future microbicide clinical trials. PLoS One. Jan 22;5(1):e878, 2010.
83)
Long CB, Madan RP, Herold BC. Diagnosis and management of community-associated MRSA
infections in children. .Expert Rev Anti Infect Ther. Feb;8(2):183-95, 2010.
84)
Gibbs, KA, Kleinman, LC, Jenkins, ST, Herold, BC and Holzman, IR. The vulnerable very low
birth weight infant: late onset bloodstream infections. Journal of Neonatal-Perinatal Medicine;
3(2): 117-125, 2010.
85)
Hollman, D, Coupey, SM, Foxy, AS and Herold, BC. Screening for Trichomonas vaginalis in
high-risk adolescent females with a new transcription mediated nucleic acid amplification test
(NAAT): Associations with ethnicity, symptoms, and prior and current STIs. J Ped Adol Gyn
May, 2010.
86)
Madan, RP and Herold, BC. Viral infection in pediatric solid organ transplantation recipients and
the impact of molecular diagnostic testing. Cur Opin Organ Transplant 15(3):293-300, 2010.
87)
Cheshenko, N., Trepanier, JB, Segarra, TJ, Fuller, AO and Herold, BC. HSV usurps eukaryotic
initiation factor 3 subunit M for viral protein translation: novel prevention target. PLoS One Jul
27;5(7):e11829, 2010.
CHAPTERS, BOOKS, INVITED REVIEWS AND LETTERS:
88)
Herold KC and Herold BC. Benefits and risks of exercise (letter). JAMA, 249: 2889, 1983.
89)
Pachman L, Herold B, Davis A, et al. Immune complexes in Kawasaki Syndrome: A review.
Progress in Clinical & Biological Research. 250: 193-207, 1987.
90)
Barmier H, Christie M, Herold B, et al. The Humoral Anti-Islet Response. In: Ginsberg-Fellner
and McEvoy, (eds) Autoimmunity and the Pathogenesis of Diabetes, Springer-Verlag, New York,
1990.
91)
Herold B, Shulman ST: The Child with Recurrent Infection. In: Stockman JA (ed), Difficult
Diagnosis in Pediatrics. W.B. Saunders Co., Philadelphia, 1990.
15
April, 2010
Herold, Betsy Clement
92)
Herold BC, and Spear PG: Viral-Host Interactions. In: Shulman ST, Phair J, and Sommers HM
(eds), The Biologic and Clinical Basis of Infectious Diseases, Fourth Edition. W.B. Saunders
Co., Philadelphia, 1991.
93)
Spear PG, Shieh M-T, Herold BC, WuDunn D. Cell Surface Receptors Required for Herpes
Simplex Virus Infection Include Heparan Sulfate Glycosaminoglycans. In: Hook M, and Switalski
LM (eds), Microbial Adhesion and Invasion. Springer-Verlag, New York, 1994.
94)
Herold BC and Spear PG: Viral-Host Interactions. In: Shulman ST, Phair J, Peterson LR, and
Warren JR (eds), The Biologic and Clinical Basis of Infectious Diseases, Fifth Edition. W.B.
Saunders Co., Philadelphia, 1997, pp.47-64.
95)
Herold BC. Therapeutic blockade of sexually transmitted disease pathogens. Ped Inf Dis
16:925-931, 1997.
96)
Oram RJ and Herold BC. Antiviral agents for herpesviruses. Ped Inf Dis 17: 652-3, 1998.
97)
Herold BC. Topical antimicrobials to prevent sexually transmitted diseases. Current Practice of
Medicine, April, 2000.
98)
Herold BC, McArdle P, and Stagnaro-Green A. Translational Medicine in the First Year:
Integrative Cores. Academic Medicine 77: 1171; 2002
16
April, 2010
Herold, Betsy Clement
INVITED INTERNATIONAL and NATIONAL SCIENTIFIC PRESENTATIONS
1996
1997
1997
2000
2001
2002
2002
2002
2002
2003
2003
2003
2003
2003
2003
2003
American Academy of Pediatrics
Chicago, IL
“Bugs and Drugs: Antiviral Therapy in Pediatrics”
Society for Pediatric Research; Pediatric Infectious Disease Symposium
Washington, D.C
“Therapeutic Blockade of Sexually Transmitted Disease Pathogens”
The Society for Glycobiology 25th Conference
Long Beach, CA
“Identification of Structural Features of Heparan Sulfate Required
for Herpes Simplex Virus Adsorption to Cells”
NIH Topical Microbicides Preclinical Workshop
Washington, D.C.
“To Spread or Not to Spread: the Case for Genital Herpes”
Society for Pediatric Research: Pediatric Infectious Disease Hot Topics
Baltimore, MD
“MRSA shows no Mercy”
Women & HIV: Translating Research into Practice
New York, NY
“Topical Microbicides Use for the Prevention of HIV and other STD’s”
22nd Annual Meeting of the American Society of Reproductive Immunology
Chicago, IL, Plenary talk:
“Topical Microbicides for Prevention of HIV and HSV”
New York Academy of Medicine
New York, NY
“The State of HIV Microbicide Research”
Office of Population Affairs; Title X Conference
New York, NY
“The Status of HIV Microbicides”
Mount Sinai Hospital 150th Anniversary Academic Symposium
New York, NY
“Topical Microbicides for the Prevention of STD’s”
New York Chapter 3 Annual American Academy of Pediatrics
New York, NY
“Impact of Microbial Resistance on Everyday Pediatric Practice”
UNOS Region 9 Coordinators Forum
New York, NY
“Smallpox Vaccination - A Re-Emerging Public Health Issue”
Alumni Day: Infant and Children’s Hospital of Brooklyn
Brooklyn, NY
“Smallpox Vaccination: Re-Emerging Public Health Issue
Scientific, ethical and Clinical Issues”
Society for Pediatric Research; Infectious Diseases Platform Session
Seattle, WA
“Herpes Simplex Virus Entry Requires Activation of Calcium Signaling Pathways”
Department of Medicine Grand Rounds, Mount Sinai Medical School
New York, NY
“Neonatal Herpes Simplex Virus Infections: New Approaches to Treatment and
Prevention; Antivirals, Vaccines, and Topical Microbicides”
550th Anniversary of the University of Istanbul: Advances in Organ Transplantation,
Istanbul, Turkey
“Prevention of Herpes Viral Infections Post-transplantation:
17
April, 2010
2003
2003
2003
2004
2004
2004
2005
2005
2005
2005
2006
2005
2006
2006
2006
2006
2007
2007
2007
Herold, Betsy Clement
Preemptive or Prophylactic Strategies”
Pfizer Global Research and Development
Groton, CT
“Antimicrobial Resistance: Impact on Decision-Making and Unmet Medical Needs”
Pediatric Grand Rounds, Flushing Medical Center
New York, NY
Neonatal Herpes Simplex Infections: Prevention and Treatment
Pediatric Grand Rounds, MSSM
New York, NY
Topical Microbicides to Prevent HIV, Genital Herpes and other STI
Infectious Disease Symposium
University of South Carolina Medical School, Charleston, SC
“Topical Microbicides for the Prevention of HSV and Other STI”
Microbicides 2004 Conference, London, England
“Interplay of Microbicides and HSV”, Basic Science Symposium Invited Lectureship
7th Annual Update in Pediatric Disease and Liver Transplantation
“CMV Disease in pediatric Liver Transplantation”, New York, NY
HIV Management 2005: The New York Course
“Topical Microbicides” April, 2005, New York, NY
Hormonal Contraception and HIV Transmission:
Links? Mechanisms? Implications?
May, 2005, New York Academy of Sciences, New York, NY
Grand Rounds, Stonybrook Medical Center, Dept of Pediatrics, Nov 16, 2005
“Topical Microbicides to Prevent HIV, HSV and other STI”
Invited Seminar Speaker, Dept of Physiology
Dartmouth Medical School; Dec. 12, 2005
HSV Modifies Mucosal Milieu: Mechanism of Immune Evasion
The Office of Special Populations and Research Training (OSPRT), DEA
NIAID, NIH, DHHS: Women and Girls HIV/AIDS Awareness Day
Keynote Speaker:
“Microbicides: Empowering Women in the Battle against HIV/AIDS & Genital Herpes”
NIH Office of AIDS Research Advisory Council (OARAC)
“Development of Surrogate Markers for Safety and Efficacy
April 6-7, 2006
American Society of Reproductive Immunology, Plenary Speaker
June, 2006, Nashville Tennessee
Genital Herpes Modifies Mucosal Milieu: Novel Mechanisms of Immune Evasion
17th Annual HIV Symposium, NY Dept of Health AIDS Institute
June 6, 2006.
Biomarkers for Evaluating Vagina Microbicides & Contraceptives: Discovery and Early
Validation; Plenary Speaker. November 15-17, sponsored by CONRAD, Alliance for
Microbicides, and Gates Foundation
2006 International Meeting of the Institute of Human Virology
“Development of Pre-clinical and Clinical Models to Predict the Efficacy & Safety of
Vaginal Microbicides”, Nov. 17-21, Baltimore, MD
Microbicide Trial Network Annual Meeting
Washington, D.C. April 20-23, 2009
“Can we use biomarkers in microbicide trials?”
University of Pennsylvania
Dept of Microbiology Graduate Student Seminar Series
“HSV Hijacks Calcium Signaling Pathways for Viral Invasion: Novel Targets for
Treatment & Prevention”, March 28, 2007
American Pediatric Society/Society for Pediatric Research Annual Meeting
18
April, 2010
2007
2007
2007
2007
2007
2008
2008
2008
2008
2008
2008
2009
2009
2009
2009
Herold, Betsy Clement
May 5-8, Toronto, Canada
“Meet the Professors” Breakfast
47th Interscience Conference on Antimicrobial Agents & Chemotherapy
Sept. 17-20, Chicago, IL
“Vaginal Microbicides”
45th Annual Meeting Infectious Disease Society of America
Oct. 4-7, San Diego CA
“Hot Topics in Pediatric Infectious Diseases”
European Commission Workshop on Microbicides
Sept. 24-25, Brussels, Belgium
“Understanding safety& activity in a mucosal setting”
Pediatric Alumni Day, AECOM/Children’s Hospital at Montefiore
October 25, Bronx, NY
“Preempting the Global AIDS Epidemic: Development of Topical Microbicides”
Dept. Obstetrics and Gynecology, AECOM, Grand Rounds
November 6, Bronx , NY
“Preempting the Global AIDS Epidemic: Development of Topical Microbicides”
Yale University, Dept Microbiology, Visiting Professor
January 17, 2008
“HSV Hijacks Different Cellular Signaling Pathways to Invade Cells by Fusion and
Endocytosis”
Alliance for Microbicide Development
April 24, 2008
“The Perfect Phase I Trial”
Arlington, VA
Patricia Spear Symposium
April 18, 2008
“Biology behind the Overlapping Epidemics of HSV & HIV: Strategies for Prevention
Northwestern University, Chicago, IL
HIV Management: The New York Course
“Preempting the Global AIDS Epidemic: Development of Microbicides”
UCSF Advances and Controversies in Clinical Pediatrics, Invited Faculty
“Fever 2008: Approach to Fever in the ER in an Era of Pneumococcal Vaccine”
“Herpes Simplex Virus: From Infancy through Adolescence”
“Judicious Use of Antibiotics”
“Prevention & Treatment of HSV Infections: Infancy through Adolescents”
December 2, 2008
Norwalk Hospital; Grand Rounds, Norwalk, CT
5th Annual Virology Colloquium, Center for Molecular and Tumor Virology
Louisiana Sate University Health Sciences Center at Shreveport
February 15-16, 2009
“Soluble mucosal immunity in the genital tract: Impact on HSV & HIV”
Microbicides Trial Network Annual Meeting,
Washington, D.C., April 20-22, 2009
“From the Bench to the Bedside & Back Again: Lessons from Microbicide Trials”
International Conference on Antiviral Research
Miami, FL May 3-7, 2009
Development of Microbicides with Broad Based Anti-infective Action
American Society for Reproductive Immunology 29th Annual Meeting,
Orlando, FL, June 5-9,2009
“Role of Soluble Mucosal Genital Tract Mucosal Immunity in the Overlapping Epidemics
of genital herpes and HIV”
19
April, 2010
Herold, Betsy Clement
2009
NIH Microbicide Phase I Meeting
Washington, DC
Nov. 30-Dec. 1, 2009
“Perfect Phase I Microbicide Trial”
2009
R BabyMount Sinai Pediatric Infectioius Disease Symposium
New York, NY December 9, 2009
Update: Diagnosis & Treatment of HSV: ER Perspective
2010
Mucosal Immunity in the Male and Female Reproductive Tract & HIV Prevention
Dartmouth Medical School Lebanon, NH
June 30-July 2, 2010
“Effects of Microbicides on Innate and Adaptive Immunity”
20