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Herpes labialis (A) With primary HSV infection, virus replicates in the oropharyngeal epithelium, ascends peripheral sensory nerves into the trigeminal ganglion. Herpes labialis (B) HSV persists in a latent phase within the trigeminal ganglion for the life of the individual. (C) Various stimuli initiate reactivation of latent virus, which then descends sensory nerves to the lips or perioral skin, resulting in recurrent herpes labialis. Source: VIRAL DISEASES OF SKIN AND MUCOSA, Fitzpatrick's Color Atlas and Synopsis of Clinical Dermatology, 8e Citation: Wolff K, Johnson R, Saavedra AP, Roh EK. Fitzpatrick's Color Atlas and Synopsis of Clinical Dermatology, 8e; 2017 Available at: http://mhmedical.com/ Accessed: May 11, 2017 Copyright © 2017 McGraw-Hill Education. All rights reserved
