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Three mechanisms for increasing surface area of the small intestine. The increase in surface area is due to folds of Kerkring, villi, and microvilli. (From Wilson, 1962, with permission.) Source: Physiologic Factors Related to Drug Absorption, Applied Biopharmaceutics & Pharmacokinetics, 7e Citation: Shargel L, Yu AC. Applied Biopharmaceutics & Pharmacokinetics, 7e; 2016 Available at: http://mhmedical.com/ Accessed: May 04, 2017 Copyright © 2017 McGraw-Hill Education. All rights reserved