Download LOYOLA COLLEGE (AUTONOMOUS), CHENNAI – 600 034

LOYOLA COLLEGE (AUTONOMOUS), CHENNAI – 600 034
M.Sc. DEGREE EXAMINATION – BIOMEDICAL INSTRUMENTATION
FIRST SEMESTER – NOV 2006
AG 02
BI 1801 - CLINICAL BIOCHEMISTRY
Date & Time : 28-10-2006/1.00-4.00 Dept. No.
Max. : 100 Marks
PART - A
Answer all the questions.
10X2=20
1. Define Down regulation & Up regulation of hormones.
2. What are amino acids? Give examples:
3. State the principle of VD Bergh reaction.
4. Which amino acid is considered as an effective physiological buffer? Why?
5. Define Bohr’s effect
6. How Sodium content is regulated when Aldosterone is high?
7. Explain the condition of hyperuricaemia::
8. Give the significance of second messengers:
9. What is the role of myoglobin?
10. Differentiate physiological jaundice from infectious jaundice.
PART - B
Answer any four of the following .
4X10=20
11. How a Myocardial Infarction becomes fatal in a patient suffering from Ischemic
Heart Disease?
12. Give an overview of carbohydrate metabolism with reference to its biomedical importance.
13. Discuss the biological role of phospholipids. Add a note on the functions of cholesterol.
14. What are the four possible outcome of inflammation? Write a description on biogenic
amines and kinins.
15. How do we examine the resting gastric contents in a patient?
16. Give the dietary source, physiological function and deficiency disorders of vitamin C.and A.
PART – C
Answer any two of the following .
2X20=40
17. (a).Describe the methods by which oxygen is transported throughout the body.
(b). Write a note on PhenylKetonuria.
18. Classify various function tests based on GFR. Discuss in detail the procedure
and interpretation of various clearance tests.
19. Explain the disorders associated with thyroid gland with special reference to their
treatment and diagnosis.
20. What are anti-oxidants? Classify them and write a detailed note on the enzymes
using oxygen as a substrate.
_____________________