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EATING DISORDERS THE ISLAMIC UNVIRSTY OF GAZA Prepared by:_ : Ahmed Abu sheer Ahmad Fayyad Under supervision Dr. Abdalkarim Radwan OBJECTIVES Discuss the signs and symptoms of eating disorders, the appropriate evaluation, and treatment options: Anorexia Bulimia nervosa nervosa Anorexia Nervosa Definition Epidemiology Diagnostic criteria Comorbidity Clinical picture Risk factor Etiology Medical complication Assessment Treatment Prognosis What is Anorexia Nervosa Anorexia nervosa is a serious, potentially lifethreatening eating disorder characterized by selfstarvation , excessive weight loss and body image distortion with an obsessive fear of gaining weight. Anorexia Nervosa- Epidemiology One of the top three chronic conditions of adolescence(asthma,obesity) Incidence rate 8/100 000 of total population. Prevalence 0.2-1% of young women Mainly affects females (95%) Female-to-male ratio is 10:1 Mean age of onset is 17,mid-teens Predominates in Western/industrialized countries- and in white, middle and upper class Median duration of illness:six years. One of the top three chronic conditions of adolescence(asthma,obesity) Incidence rate 8/100 000 of total population. Prevalence 0.2-1% of young women Mainly affects females (95%) Female-to-male ratio is 10:1 Mean age of onset is 17,mid-teens Predominates in Western/industrialized countries- and in white, middle and upper class Median duration of illness:six years. DSM-IV CRITERIA-Anorexia Nervosa Refusal to maintain minimal normal weight for age and height (< 85% of expected body weigh INTENSE FEAR of gaining weight or becoming FAT. Increased emphasis on weight/shape, body image distortion, OR denial of the seriousness of the current low body weig Amenrrohea at least for three consecutive menstrual cycle 2 types of Anorexia Nervosa Restricting type Primarily accomplishes weight loss through dieting, fasting, exercise No regular bingeing or purging Binge-eating-purging engages in binges (large amount of food consumed) following by purging (vomiting or use of laxatives) Binge-Purge type includes all of the features of Anorexia Nervosa (restriction, low weight, fear of fat, etc.) Regular bingeing and purging Methods of purging may include self-induced vomiting, laxative, diuretic, or enema use You may think- “isn’t that Bulimia?” but the key is they’re underweight Anorexia Nervosa ICD criteria Body weight is consistently 15% less (or lower) than that expected for height and age, or body mass index is 17.5 or less. Weight loss is caused by the avoidance of foods perceived to be fattening, along with one or more of the following behaviors: self-induced vomiting, purging, excessive exercise, use of appetite suppressants and/or diuretics. Distorted body image perception driven by an intense, irrational fear of becoming fat, leads to the desire to remain at a low body weight. Anorexia Nervosa ICD criteria Amenorrhea (abnormal absence of a minimum of three successive menstrual cycles) in women, and loss of libido in men. There may be changes in growth hormone, cortisol, thyroid hormone and insulin. Puberty in girls and boys may be delayed if the onset of anorexia nervosa is prepubertal, but once recovery from the illness is made, it will often progress normally. Psychiatric Comorbidity Consequence of starvation 50% have major affective disorder 33% have social phobia 25% have obsessive compulsive disorder Binge-purge sub-type 80% have depression 10-20% have alcohol and substance misuse Personality disturbance 25% of restricting anorexia nervosa have avoidant ,dependent or obsessional personalities 40% of binge-purge sub-type of anorexia nervosa have borderline or histrionic personality disorder. The clinical picture of Anorexia Nervosa Food restriction Excessive exercise Preoccupations with food, eating, and calories Social Isolation Mood irritability, Depression, Obsessive-compulsive behavior Avoiding social situations that involve food Unusual eating habits (ie. cutting food into tiny pieces, picking at food) Going to the bathroom right after meals Eating alone, at night, or in secret Cooking for others, but not eating themselves Wearing baggy clothes to hide weight loss Frequently checking weight on scale Risk Factors for Anorexia Female Adolescent Living in industrialized nation Family history of obesity or addiction Early puberty Childhood obesity Low self-esteem Activities with weight/shape demands Wrestling, dance, etc. Diabetes Personality Disorders (Cluster) Sexual and physical abuse Etiology of anorexia nervosa: Genetic causes of anorexia : Twin studies suggest that anorexic traits and the syndrome have a significant genetic component. If one identical twin has anorexia, the other has more than a 50% chance of also developing it. Research suggests that a genetic predisposition to anorexia may run in families.. Family studies have shown that the prevalence of anorexia nervosa is 7 to 12 times higher among relatives of AN than among controls. In fact, it is common to discover that someone with anorexia has a mother or sister with this eating disorder as well. Biological cause Brain chemistry also appears to play a significant role. . Research has shown decreased levels of serotonin in the brain (a chemical, or neurotransmitter used by nerve cells to communicate and which controls appetite and mood). and contribute to other symptoms of anorexia nervosa such as depression, impulsiveness, obsessive behaviors, or other mood disorders. The Psychological cause: Severe trauma ,sever life event, difficulties and emotional stress (such as the death of a loved one or sexual abuse) during puberty or prepuberty. People with anorexia may have psychological and emotional characteristics that contribute to anorexia. They may have low selfesteem , feelings of insufficiency and rigid thought patterns . They may have obsessive-compulsive personality traits that make it easier to stick to strict diets and forgo food despite being hungry. They may have an extreme drive for perfectionism, which means they may never think they're thin enough. Sociocultural cause: Modern Western culture often cultivates , reinforces and puts a high value on thin or lean bodies The splashed with images of waif-like media are models and actors. Success and beauty are often equated with being thin. Peer pressure may fuel the desire to be thin, particularly among young girls. Teenagers are especially vulnerable to social and peer pressure, which may explain why peak rates of anorexia occur in the teen years. social pressures that can contribute to anorexia. This includes participation in an activity that demands slenderness, such as ballet, gymnastics, or modeling. Medical complications of anorexia: starvation state Dermatological: Dry Skin and Hair Loss , lanugos-like facial hair, thinning scalp hair, edema, pale Hematological: leucopenia, anemia, thrombocytopenia. . Reproductive :Infertility ,Low-birth weight infant Heart: arrhythmias, bradycardia , hypotension , weakened heart muscle Stomach and Intestines :slow movement in the intestinal tract leading to fullness, bloating, nausea and constipation . Bone: osteoporosis, pathological fracture Other: Hypothermia, Poor immunity Medical complications of anorexia: starvation state Endocrine: Reduced levels of estrogen, testosterone, and growth hormones may explain growth retardation and delayed pubertal changes seen in anorexic patient, amenorrhea CNS: the brain shrinks,ventricular space increase in size,cognitive impairment, Peripheral neuropathy Renal :Renal calculi . Dental changes: Tooth enamel erosion, dental caries ,dentinal hypersensitivity assessment Clinical assessment of anorexia nervosa should include full psychiatric and medical history. Full physical examination include vital signs (height, weight, temperature, supine & standing blood pressure and heart rate), examine skin for langue (fine, downy hair that may grow as the result of malnutrition) and/or scars on hands from self-induced vomiting, check for enlargement of parotid gland, erosion of dental enamel, and consider including the following tests: CBC ,Glucose ,Liver Function, Thyroid Function, Analysis of electrolyte levels, BUN, creatinine & albumin (blood and urine). Monitor ketones Bone density tests. assessment Physical examination are required to exclude organic disorder such as Malignancy, thyroid disorder, irritable bowel disease. Ask the patient how do they feel about their body Ask a bout eating habits. Do they take amphetamines to suppress appetite, laxatives, ipecac Treatment of Anorexia: Interdisciplinary Approach Medical Monitoring Nutritional Rehabilitation Psychotherapy Medical treatment for anorexia The first priority in anorexia treatment is to address and stabilize any serious health issues. Hospitalization may be necessary to prevent starvation, suicide, or a medical crisis. Dangerously thin anorexics may also need to be hospitalized until they reach a less critical weight. Outpatient treatment is an option when the patient is not in immediate medical danger. you may need to be admitted to hospital so that fluids and nutrients that you have lost from your body can be replaced. There are no medications specifically approved to treat anorexia. However, antidepressants are often prescribed to treat depression that may accompany anorexia. Nutritional therapy for anorexia A second component of anorexia therapy is nutritional counseling. In nutritional counseling, a nutritionist or dietician teaches the patient about healthy eating, proper nutrition, and balanced meals. The nutritionist also helps the person develop and follow meal plans that include enough calories to reach or maintain a normal, healthy weight Psychotherapy Cognitive Behavioral therapy : Cognitive Behavioral therapy is one of the most effective therapies for anorexia. In cognitive behavioral therapy, the person learns to replace negative, unrealistic thoughts and beliefs with positive, realistic ones. The person is also encouraged to acknowledge their fears and to develop new, healthier ways of solving problems, Cognitive therapy also involves education about anorexia. Psychotherapy Promotes healthy eating behaviors through the use of rewards, reinforcements, self-monitoring, and goal setting. Teaches the patient to recognize anorexia triggers and deal with them using relaxation techniques and coping strategies. Group therapy Group therapy can be very beneficial to someone trying to recover from anorexia nervosa. Allows people with anorexia to talk with each other in a supervised setting. Helps to reduce the isolation many anorexics may feel. Group members can support each other through recovery and share their experiences and advice. Family Therapy Family therapy usually involves the people that are living with or very close to the person with the eating disorder. This could include parents, siblings, spouses and even grandparents. Usually an eating disorder indicates that there are problems within the family. Some problems could include martial problems, substance abuse, physical or sexual abuse, lack of communication, or difficulty in expressing feelings. All these issues can be discussed and worked on in family therapy. In order to solve these problems, the families must be willing to participate in therapy and be willing to make changes in their own behaviors. Prognosis: Median duration is six year. 50 - 70% of people recover from anorexia nervosa 30% have poor prognosis. Mortality rate: 5-18% Death is due to suicide in 24-50% of cases, and medical complication in 50% Bulimia episodic, uncontrolled rapid ingestion of food over a short period of time followed by purging. compensatory measure to rid the body of the excessive calories. The food has a sweet taste, high calorie count. The binging is done in secret and alone Bulimia induced purging use of laxatives,diuretics, or enemas weight fluctuations- but patient is usual of normal weight. DSM-IV CRITERIA- Bulimia Episodes of binge eating with a sense of loss of control Binge eating is followed by compensatory behavior of the purging type (self-induced vomiting, laxative abuse, diuretic abuse) or nonpurging type (excessive exercise, fasting, or strict diets). Binges and the resulting compensatory behavior must occur a minimum of two times per week for three months Dissatisfaction with body shape and weight Symptoms dehydration from the vomiting electrolyte imbalance erosion of tooth enamel from gastric acid tears in the esophagus or gastric mucosa. May also have depression ( 71%) anxiety disorders, substance abuse. EPIDEMIOLOGY Bulimia Occurs in 1-5% of high school girls As high as 19% in college women ASSOCIATED FACTORS History of dieting in adolescent children Childhood preoccupation with a thin body and social pressure about weight Sports and artistic endeavors in which leanness is emphasized Women whose first degree relatives have eating disorders– 6 to 10 fold increased risk for developing an eating disorder ASSOCIATED PSYCHIATRIC CONDITIONS affective disorders anxiety disorders obsessive-compulsive disorder personality disorders substance abuse. Assessment Bulimic patients often have hoarseness,parotid gland enlargement (Chipmunk) ,tooth enamel erosion,scarred fingers. TREATMENT AND OUTCOME Treatment priority the restoration of nutritional status and life threatening physical problems. Behavior Modification Family therapy group therapy like a 12 Step approach education about eating disorders, the causes, the effects on the body, the issues and the situations that may trigger a sense of loss of control and lead to acting out with food relaxation techniques medications (Prozac) Periactin is an appetite stimulant. Have tried Lithium and Thorazine HOSPITALIZATION Severe malnutrition Dehydration Electrolyte disturbances Cardiac dysrhythmia Arrested growth and development Physiologic instability Failure of outpatient treatment Acute psychiatric emergencies Comorbid conditions that interfere with the treatment of the ED NUTRITION Goal: regain to goal of 90-92% of IBW Inpatient treatment varies by facility Oral liquid nutrition Nasogastric tube feedings Gradual caloric increase with “regular” food Parenteral nutrition rarely indicated OUTCOME 50% good outcome 25% intermediate outcome Return of menses and weight gain Some weight regained 25% poor outcome Associated with later age of onset Longer duration of illness Lower minimal weight Overall mortality rate: 6.6%