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Unit Three Respiratory System Lisa Michelek Human Respiration • The transport system delivers nutrients obtained in the digestive system to the body’s cells where the nutrients combine with oxygen to release energy needed to carry out the life processes of the organism. • The life process responsible for releasing energy from nutrients is respiration. • In organisms, respiration involves an exchange of gasses between the organism and its environment. Human Respiration • Respiration in humans is external, internal, and cellular. • External respiration occurs outside the cells and involves the exchange of gases between the lungs and the blood. • Internal respiration takes place when gases are exchanged between the blood and body’s cells. • Cellular respiration is the energy releasing process that takes place inside the cells. Human Respiratory System • The respiratory system transports gases between the external environment and the internal surfaces where gas exchange occurs. • In humans, air from the environment moves through a series of passageways to the lungs, where gas exchange occurs. Human Respiratory System • Air first enters the respiratory system through the nostrils and mouth. • From the nostrils, air moves through hollow cavities, called nasal passages, to the throat. • The nasal passage is lined with mucous membranes and hair-like structures called cilia. • Air is filtered by cilia where it is moistened & warmed by the mucous membranes before it enters pharynx (back of throat). Human Respiratory System • The back of the throat is called the pharynx. • Located in the pharynx is the glottis, which is the opening to the windpipe. • A flap of tissue called the epiglottis covers the glottis during swallowing. • This prevents food from entering the glottis and trachea. • If food enters the windpipe, choking occurs. Human Respiratory System • The trachea (windpipe) transports air to the bronchial tubes. It is kept open by rings of cartilage. • The trachea is lined with cilia that beat constantly in one direction. • The cilia move foreign material, such as dust, pollen, and smoke, out of the trachea and back to the nasal passages. • The cilia can be damaged by smoking or air pollution. Human Respiratory System • At the upper end of the trachea is the larynx (voice box). • The larynx contains the vocal cords. • Different sounds can be produced in the larynx by vibration of the cords. • The pitch of a sound is determined by the amount of tension in the cords. Human Respiratory System • The trachea divides into two bronchial tubes called bronchi. • The bronchi branch into the lungs. – Bronchial tubes are also lined with cilia. • The bronchi further divide into smaller tubes called bronchioles. – The bronchioles are lined with a mucous membrane. • The bronchioles continue to divide, ending in air sacs in the lungs called the alveoli. Human Respiratory System • Gas exchange takes place at the alveoli. • The alveoli are also called air sacs. • They are moist and thin, and are surrounded by a network of blood capillaries. Breathing • Breathing is the movement of gases between the atmosphere and the lungs. • Air is moved into the lungs by inhalation and moved out of the lungs by exhalation. • The oxygen present in air is brought into the body and carbon dioxide is given off into the air. • Air moves into and out of the lungs because of the differences in air pressure between the chest cavity and the outside environment. Breathing • The lungs have no muscle tissue to help in inhalation or exhalation. • Air enters and leaves the lungs because of air pressure changes in the chest cavity. • The pressure changes are caused by the contraction and relaxation of the diaphragm and rib muscles during inhalation and exhalation. Breathing • The diaphragm is a dome-shaped muscle located at the bottom of the chest cavity. • When you inhale, the diaphragm moves down and the rib muscles move upward and outward. – This movement enlarges your chest cavity, and air is forced into your lungs. • When you exhale, the diaphragm moves up to its original curved position and the ribs move in, making your chest cavity smaller and forcing air out of the lungs. Breathing Rate • Breathing rate is affected by foreign particles from smoking or air pollution, and the oxygen (O2), carbon monoxide (CO), and carbon dioxide (CO2) levels in the blood. • The most important factor in controlling breathing rate is the concentration of carbon dioxide (CO2) in the blood. • An increase in blood CO2 concentration increases breathing rate. • When the blood CO2 level decreases, breathing rate decreases. Cellular Respiration • Cellular respiration is the energy-releasing process that takes place inside living cells and involves the exchange of gases between the blood and tissue fluid and the cells. • During cellular respiration, oxygen combines chemically with sugar (glucose) to release energy (ATP – adenosine triphosphate). • Molecules of carbon dioxide and water are waste products of this process. Aerobic Cellular Respiration • In aerobic respiration, oxygen is required. • Glucose is broken down completely to carbon dioxide and water. • The chemical energy of the glucose molecule is released and used to make ATP. Anaerobic Cellular Respiration • In anaerobic respiration, or fermentation, oxygen is not required. • Glucose is partially broken down into lactic acid or alcohol and carbon dioxide, by yeasts and bacteria. • During prolonged exercise, muscle cells are using oxygen faster than the circulatory system can supply it. • In this case, lactic acid may build up in the muscle tissue and is associated with muscle fatigue. Respiratory System Disorders • Bronchitis – An inflammation of the lining of the bronchial tubes. – The bronchioles secrete too much mucus and become small and irritated. – Respiratory cilia cannot clear the passages of the mucus and particles that clog them. – Affected persons are short of breath and often cough up mucus. Respiratory System Disorders • Asthma may be caused by: • Allergens: House dust, dust mites, mold spores, pollen and animal dander • Bacterial and Viral Infections: The common cold, influenza, sinusitis and bronchitis • Irritants: Air pollution, smoke, car fumes, perfume, paint odors and cold air • Other: Weather changes, exercise, GE reflex, stress and emotions. – During an asthma attack, the bronchial tubes narrow, which prevents oxygen from entering the lungs. The person may begin to have a dry cough and chest tightness followed by wheezing. – Treatments include oral and inhaled steroids, albuterol, and other medications to prevent and control an asthma attack. Respiratory System Disorders • Emphysema – A lung disease in which the alveoli become large and break down. – The lungs become less elastic and the amount of air they can hold decreases. – A person with emphysema experiences shortness of breath with the slightest activity. – There is no cure for emphysema, but life can be prolonged with proper treatment. – Smoking is one cause of emphysema. Respiratory System Disorders • Lung Cancer – Is an uncontrollable growth of tumors in the lungs. – There is a proven relationship between lung cancer and cigarette smoking. Respiratory System Disorders • Pneumonia – Is an infection of the lungs that is caused by a bacteria or virus. – The alveoli of the lungs fill with fluid preventing proper exchange of gases and making breathing difficult. – Some types of pneumonia are treated with antibiotics. Respiratory System Disorders • Cystic Fibrosis – Autosomal recessive disorder in which defective gene/protein causes body to produce unusually thick, sticky mucus – Affects lungs most directly by clogging them with mucus and resulting in bacterial infections – Also affects pancreas and it’s ability to generate healthy enzymes to digest food/nutrients Overview of Respiratory System • http://www.youtube.com/watch?v=zRv5tN CMpyY • http://www.youtube.com/watch?v=AJpur6 XUiq4 • http://www.youtube.com/watch?v=AyUtdqi OgCA • http://www.youtube.com/watch?v=00jbG_c fGuQ