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Respiratory System Internal Respiration • Internal respiration is the process by which the gases in the air that has already been drawn into the lungs by external respiration are exchanged with gases in the blood/tissues so that carbon dioxide (CO2) is removed from the blood and replaced with oxygen (O2). External Respiration • External respiration concerns the process by which external air is drawn into the body in order to supply the body with oxygen gas, and the (used) air is expelled from the lungs in order to remove carbon dioxide from to body Cellular Respiration • Internal respiration is important to cells because without oxygen, all body functions would cease due to a lack of ATP Main Function • Gas Exchange – To work closely with the cardiovascular system to supply the body with oxygen and to dispose of carbon dioxide Organs Include 1. Nose 2. Pharynx 3. Larynx 4. Trachea 5. Bronchi – And their smaller branches 6. Lungs – Containing alveoli (terminal sacs) The Nose • Externally visible – Nostrils – External Nares – Internally – Nasal Cavity – Divided by nasal septum – Olfactory receptors in the superior cavity in the mucosa Function of Nose • Mucosa lining rests on thin walled veins that warm the air • Mucous produced by the mucosa, moistens the air and traps bacteria and other particulates Pharynx • 13cm muscular passageway (Throat) • Food and air passage – NasopharynxSuperior – Oropharynxcentral – LaryngopharynxInferior Pharynx • Tonsils are located in the pharynx – Pharangeal or Adenoids (superior) – Palatine (oropharynx) – Lingual (base of tongue) Epiglottis • epiglottis guards the entrance of the glottis • normally pointed upward during breathing with its underside functioning as part of the pharynx • during swallowing elevation of the hyoid bone draws the larynx upward; and prevents food from going into the trachea; instead directs it to the esophagus Larynx • AKA Voice box, routes air, role in speech • Inferior to pharynx • Eight rigid hyaline cartilage – Largest is Thyroid cartilage (Adam’s Apple) – Protrusion angel 90˚ in males and 120˚ in females • Cartilage flap – Epiglottis protects opening Larynx • Mucous Membrane forms Vocal folds (vocal cords) – allow us to speak • Glottis - Slit-like passageway between the vocal folds Trachea • Windpipe • Goes to the 5th Thoracic Vertebrae • Reinforced with Cshaped cartilage rings to keep it open anteriorly and allow flexibility for food to pass through the esophagus posteriorly Main Bronchi • Division of the trachea • Runs obliquely • Ends at the hilus (medial depression of the lung) – The right is wider and shorter and more often the site of inhaled objects Bronchioles • Primary bronchi subdivide into smaller branches • Bronchial Tree – Secondary Bronchi – Tertiary Bronchi – Then Bronchioles Alveoli • Small cavity or air sac – Millions of clustered alveoli look like bunches of grapes • Site of gas exchange • Make up a bulk of the lungs – Also stroma which is elastic Diaphragm • sheet of internal muscle that extends across the bottom of the rib cage • The diaphragm separates the thoracic cavity (heart, lungs & ribs) from the abdominal cavity and performs an important function in respiration. Diaphragm • Inspiration: During inhalation, the diaphragm contracts, thus enlarging the thoracic cavity (the external intercostal muscles also participate in this enlargement). This reduces intra-thoracic pressure: In other words, enlarging the cavity creates suction that draws air into the lungs Diaphragm • Expiration: When the diaphragm relaxes, air is exhaled by elastic recoil of the lung and the tissues lining the thoracic cavity in conjunction with the abdominal muscles Gas Exchange • Diffusion, the spontaneous movement of gases, without the use of any energy or effort by the body, happens between the gas in the alveoli and the blood in the capillaries in the lungs. CO2 and O2 • The hemoglobin molecule is the primary transporter of oxygen • Oxygen from the air enters the blood, and carbon dioxide from the body trades places with the oxygen by leaving the blood and entering the alveoli. • Carbon dioxide is then exhaled out of the lungs. • Oxygen must enter the blood and carbon dioxide must leave the blood at a regular rate for our body to function correctly. Pulmonary Circulation • The Pulmonary circulation is the portion of the cardiovascular system which transports oxygen-depleted blood away from the heart, to the lungs, and returns oxygenated blood back to the heart. Systemic Circulation • Systemic circulation is the portion of the cardiovascular system which transports oxygenated blood away from the heart, to the rest of the body, and returns oxygendepleted blood back to the heart. • Carbon Dioxide is picked up along the way and is also carried back to the heart to be exhaled through the lungs. Bone Structures • Conchae- Increase surface area of mucosa and create turbulance • Palate- Separates from oral cavity – Hard palate (bone ) is anterior – Soft palate(tissue) is posterior Cleft Palate • Genetic Defect • Bones do not fuse medially • Causes Problems: – Breathing – Chewing – Speaking Paranasal Sinuses • Surround the nasal cavity • Located in Bones: – – – – Frontal Sphenoid Ethmoid Maxillary Function of Sinuses • Lighten the skull • Resonance for speech • Produce mucous • Nasolacrimal ducts – Drain tears from eyes Rhinitis, Sinusitis, Sinus Headache • Inflammation of the nasal mucosa – Virus – Allergens • Mucosa is continuous so that these infections often spread Lungs • Occupy entire thoracic cavity (except mediastinum where the heart is) • Narrow superior portion (apex) is deep to clavicle • Broad base rests on the diaphragm • Left lung = 2 lobes • Right lung = 3 lobes Lungs • Surface covering is visceral serosa called Pulmonary Pleura • Walls of the cavity are covered with parietal pleura • Pleural fluid reduces friction during breathing movements Pleurisy • Inflammation of the pleura due to decreased secretion of pleural fluid • Pain with each breath • Excess fluid may hinder breathing Respiratory Membrane • Thin squamous epithelial cells • Alveolar pores connect sacs • External surfaces have a “cobweb” of capillaries • Respiratory Membrane is the Air / Blood barrier Airway Obstruction • Heimlich Maneuver – Physical Procedure where someone assists in dislodging a blockage • Tracheostomy – Surgical Procedure cuts a new opening