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DINATEC Diversified Nutri-Agri Technologies Inc., A Systems Approach to Mycosis and Mycotoxicosis Management Presented by Dr. Martin Moreira Ph. D. INTRODUCCION Aspergillus spp, Penicillum spp; and Fusarium ssp Mycotoxins comprise a diverse group of persvasive an naturally occurring secondary fungal metabolites that are strongly implicated in disease and diverse pathologies in animals. Consequently, there is a critical necessity for practical and viable integrated methodologies of detoxification. I.M.M. CONCEPT INTEGRATED MYCOTOXIN MANAGEMENT DINASIL Polielectric adsorption DINAPROP Mold inhibition DINAFERM Biotransformation DINAMUNE Immunostimulation IMMUNOSUPRESSION PATHOGENIC MICRO-ORGANISMS VIRAL AGENTS MYCOTOXINS USE CHART I.M.M. BROILERS DAY 42 DAY 21 DAY 1 DINAPROP DINASIL DINAFERM DINAMUNE 1KG/ TM 2.5 KG/TM 500 GR/TM 500 GR/TM PRODUCT SPECIFICATIONS DINAMUNE INMUNOESTIMULANT DINAMUNE Incorporates a 1-3 link 100% natural Beta Glucan derivative as one of the most important active ingredients. This Beta Glucan is derived from the cell walls of the yeast known as S. cerevisiae. Use is indicated whenever there is a diminished immune system. This condition may be aggravated by the hosts succeptability to contagious viral or bacterial deseases and by the presence of certain types of immunosuppresant agents such as many types of mycotoxins. DINAMUNE BETA-GLUCAN Powerfull Immunological Stimulant. Has Anti-oxidant effects. Aids in the regeneration and repair of organic tissue. Has adjuvant characteristics with antibiotics, vaccines,anti-parasites and mycotoxin adsorbants and mold inhibitors. Has antineoplastic effects. DINAMUNE BETA-GLUCAN 100% safe and non toxic. Will not over stimulate the immune system nor will it elicit an anti-immune response Will not interfere with other medication being concurrently administered. Very easy to apply DINAMUNE ASSIMILATION IN THE DIGESTIVE TRACT The digestive tract is lined with entherones and entherocytes. These organisms produce a sticky filamentous material that is called Glycocalix. There are two types of receptors bound to this Glycocalix. One such receptor is highly specific and will adhere to long chain type molecules engulfing them and pulling them towards the interior area of the cellular walls in the digestive system. This is one of the ways that DINAMUNE works. The process wherein this is accomplished is called Pinocytosis or Endocytosis. DINAMUNE ASIMILATION IN THE DIGESTIVE TRACT Polysacharides are transported through the inner lining of the lateral intestinal walls towards the lymphatic system and from there into the blood stream. DINAMUNE MODE OF ACTION Beta Glucans are able to activate macrophages or macrophage like cells within the reticuloendothelial system by stimulating a specific receptor site on the macrophage. Macrophages are able to trap and engulf foreign substances. This event will initiate a cascade of immunological events that will result in the stimulation and strenghtening of the overall immune system alerting it and mobilizing it in a specific sequence. The result is the creation of an immunological bank or reserve that will offer continued protection to the host organism and help it to ward off desease. INTEGRATED MYCOTOXIN MANAGEMENT PROGRAM The End ……for now…. DINATEC Diversified Nutri-Agri Technologies Inc., Visit us at http://www.dinatec.com