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Sections 6 Significances of Inflammation 1. Significances ( 1 ) Inflammation is fundamentally a protective response whose ultimate goal is torid the organism of both the initial cause of cell injury and the consequences of such injury, the necrotic cells and tissues. (2) Inflammatory response is closely intertwined with the process of repair. (3) The inflammatory response occurs in the vascularized connective tissue. (4) Inflammatory response of both vascular and cellular responses are mediated by inflammatory mediators chemical factors derived from plasma or cells and triggered by the inflammatory stimulus. (5) However, inflammatory responses are not perfect that may be potentially harmful. 2. Aspects of inflammation (1) Many systemic and local host factors influence the adequacy of the inflammatoryreparative response. ① Nutrion condition ② Immune condition ③ Endocrine condition ④ Characteristics of inflammatory organ or tissue (2) The aspects of inflammatory factors ① Character ② Quantity ③ Duration of injury