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Major Concepts of Anatomy and Physiology Part 1: Organization of the Human Body What is A&P? Anatomy: The study of the structure of the human body. Physiology: The study of the function of the human body. Subdivisions of Anatomy Gross Anatomy: Studies structures visible to naked eye. Histology: Studies structure of tissues visible through a microscope. Neuroanatomy: Studies the structures of the human nervous system. Embryology: Studies the development of human embryos. Radiographic Anatomy: Studies the structures visible via x-ray. Subdivisions of Physiology Neurophysiology: Studies the function of the human nervous system Cardiophysiology: Studies the human cardiovascular system. Immunology: Studies the structure & function of the immune system. Endocrinology: Studies the function of hormones and their effects. Pathophysiology: Studies the changes brought on by disease and aging. Homeostasis Homeostasis: The healthy internal balance of the human organism. The body will always attempt to return to homeostasis if change occurs. Feedback Systems are used to maintain homeostasis. E.g. blood glucose, body temperature, etc. Major fluctuations may indicate a problem! Feedback Mechanisms Negative Feedback Mechanisms: Maintains the body condition in question within a small “normal range” of its set point. Examples: Blood sugar range (80-120mg/ml) Body Temperature (36.5-38*C) Blood pH Your thermostat! Feedback Mechanisms Positive Feedback Mechanisms: Strengthens of reinforces a change where the response to a stimulus actually increases the original stimulus. Produces a fairly rapid change. Examples: Labor Hierarchy of Complexity 6 Levels of the Hierarchy Chemical Level Cellular Level Tissue Level Organ Level System Level Organism Level Moves from simple to complex. Chemical Level The atoms and molecules that make up the cells of the body. Subatomic Particles: Smaller than atoms Include protons, neutrons & electrons Atoms: The smallest unit of the elements Formed by combinations of the subatomic particles Chemical Level Elements: Fundamental substances composed of atoms Chemically alike &cannot be separated into smaller substances by typical methods Include Oxygen, hydrogen, carbon, & nitrogen Molecules: Composed of groups of atoms Includes things like Glucose & Macromolecules Macromolecules: Composed of hundreds or thousands of molecules Includes proteins, fats, carbohydrates, DNA, RNA Cellular Level Organelles: Microscopic structures contained inside cells Carry out individual functions Include Mitochondria, endoplasmic reticulum, lysosomes Cells: The basic building block of all organic organisms (living things) Tissue Level Tissue: A mass of similar cells that perform the same specific function FOUR PRIMARY TISSUES Epithelium Tissue Connective Tissue Muscle Tissue Nervous Tissue Organ Level Organ: Structure composed of two or more separate tissue types working together to carry out a particular function Distinct gross anatomical boundaries Include stomach, heart, brain, etc. System Level Organ System: A group of organs connected together to accomplish a unique collective function Example: Digestive system Separate organs include the esophagus, stomach, small & large intestines Functions include digestion, absorption, and excretion Organism Level Organism: A single complete individual Composed of a number of different organ systems 11 Systems in the Human Integumentary Skeletal Muscular Cardiovascular Nervous Endocrine Respiratory Digestive Lymphatic Reproductive Urinary Six Characteristics of Living Organisms 1. Metabolism: All chemical reaction occurring within living cells. 1. 2. 2. 3. Anabolism: Synthesis reactions to combine small molecules to form larger ones. Requires an input of energy. Catabolism: Reactions reduce large, complex substances into simpler ones. Releases energy. Growth: An increase in size through division and/or enlargement of cells. Differentiation: The process of developing unspecialized cells into specialized cells with specific structure and function. Six Characteristics of Living Organisms 1. 2. 3. Movement: Includes motion of a body part or materials through the body. Responsiveness: The ability to detect and respond to changes in the environment. Reproduction: The process of producing a new organism or forming new cells. Anatomical Position The anatomical position is the standard reference position for A&P. Requires a person to… Stand with feet flat on the floor Arms at the sides Palms, face, eyes, and feet face forward All descriptions assume the body is in this position. Directional Terms Superior: Toward the top of the head Inferior: Below or toward the feet Anterior or Ventral: Front Posterior or Dorsal: Back Medial: Toward the midline/midsagittal plane Lateral: Away from the midline Proximal: Closer to midline or the point of limb attachment Directional Terms Distal: Farther away from the midline or point of limb attachment Superficial: Closer to the surface of the body Deep: Farther from the surface of the body Anatomical Planes Sagittal Plane: Extends vertically from head to toes; divides the body into left and right portions. Midsagittal Median Plane: Passes exactly through midline (middle) of the body; divides the body into equal halves. Parasagittal Plane: Any sagittal plane that passes through the body to the left or right of the midline; divides the body into unequal left & right portions. Anatomical Planes Frontal Coronal Plane: Vertically oriented plane At right angles perpendicular to the sagittal plane Divides the body into a front (anterior) and back (posterior) portion Anatomical Planes Transverse Plane: Passes through the body horizontally Perpendicular to the long axis of the body Divides the body into top (superior) and bottom (inferior) portions. Typical plane of Computerized Tomography (CT) scans Anatomical Planes Oblique Plane: Passes through the body at an angle Between the transverse plan and either a sagittal or frontal plane. Surface Anatomy Axial Region: The area of the body closest to the midline. Consists of.. head neck Trunk Thoracic region (chest above diaphragm) Abdominopelvic region (below diaphragm) Surface Anatomy Appendicular Region: Are of body farthest away from the midline. Consists of the Appendages (upper and lower limbs, extremities). Brachium: Arm from shoulder to elbow Antebrachium: Forearm from elbow to wrist Carpus: Wrist area Metacarpus: Hand between carpus & phalanges Manus: Hand Digits (Phalanges): Fingers Thigh: From hip to knee Crus (Shank): From knee to ankle Tarsus: Ankle between leg and metatarsus Metatarsus: Foot from ankle to toes. Pes: The foot Digits (Phalanges): The toes Body Cavities Dorsal Cavity: Lined by the meninges (dura mater, arachnoid mater, and pia mater). Ventral Cavity Cranial Cavity: Contains the brain; enclosed in the skull. Vertebral or Spinal Cavity: Contains the spinal chord; enclosed in the vertebral column. Thoracic Cavity: Contains the heart, lungs, & upper digestive system organs. Abdominopelvic Cavity: Contains the stomach, liver, gallbladder, spleen, pancreas, urinary bladder, small & large intestine. Kidneys located BEHIND abdominopelvic cavity. Organs located in these cavities are referred to as viscera. Abdominopelvic Cavity 4 Abdominopelvic Quadrants: Right Upper Quadrant Left Upper Quadrant Left Lower Quadrant Right Lower Quadrant Abdominopelvic Cavity 9 Abdominopelvic Regions Right Hypochondriac Region: Liver, gall bladder Epigastric Region: Liver, stomach, pancreas Left Hypochondriac Region: Stomach, spleen Right Lateral or Lumbar Region: Ascending colon, gall bladder Umbilical Region: Stomach, transverse colon, small intestine, pancreas Left Lateral or Lumbar Region: Small intestine, descending colon Right Inguinal or Iliac Region: Cecum, small intestine Hypogastric Region: Small intestine, rectum, urinary bladder, reproductive organs Left Inguinal or Iliac Region: Small intestine, sigmoid colon