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HUMAN HEART ANATOMY Figure 21.2. Location of the Heart in the Thoracic Cavity. The heart is situated within the middle portion of the mediastinum, immediately posterior to the sternum. (a) Anterior view of the open chest cavity, showing the position of the heart and major vessels relative to the lungs. The sectional plane indicates the orientation of part (c). (b) Relationships between the heart and the pericardial cavity. The pericardial cavity surrounds the heart like the balloon surrounds the fist (right). (c) Diagrammatic view showing the position of the heart and the location of other organs within the mediastinum. In this sectional view, the heart is shown intact so you can see the orientation of the major vessels. (d) A superior view of a horizontal section through the trunk at the level of vertebra T8. Figure 21.3