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VIRUSES Viruses are not considered ALIVE because they are: – Acellular (not made of cells) – No metabolism – No homeostasis – No reproduction outside of host cell T4 Bacteriophage- virus that infects bacteria So what is a virus? Viruses are particles made of only 2 things: – Protein (makes up a cover called the capsid) – Genetic material (either DNA or RNA, but not both) Human Papillomavirus- causes WARTS (including genital and anal warts) Typical Viruses T4 Bacteriophage Influenza virus A virus infecting a bacterium: Diseases caused by viruses: Warts Cervical cancer Herpes simplex 1 (cold sores) Herpes simplex 2 (genital sores) Chicken pox Shingles Mononucleosis Roseola Ebola Polio Common cold Rubella Yellow fever Encephalitis Rabies Measles Mumps Influenza Leukemia HIV The only hope you have if you’ve been infected with a virus is: Your own immune system! Vaccinations Weakened viruses (attenuated) or pieces of viruses are introduced into the body Your immune system (B cells) will make ANTIBODIESproteins that will attach to a virus and alert your immune system to destroy them Ebola RNA virus 4 types: Ebola Zaire, Sudan, Reston and Tai Reston only infects monkeys Transmission: close person to person contact and body fluids Corpses highly infectious Zaire strain 90% fatal Blood vessels attacked and destroyed- patient bleed to death internally Ebola, continued Doctors working with Ebola patients wear “space suits” to prevent becoming infected African countries with recorded Ebola outbreaks: Small Pox DNA virus Transmitted through droplets of water while coughing or pus from blisters Once used as a biological warfare technique during French and Indian War Symptoms appear after 7-14 days – – – – – High fever Malaise Back ache Headache Followed by rash Treatment for Small Pox Last recorded case of small pox on Earth was this man in Somalia Treatments: IV fluids, fever-reducers, antibiotics to prevent secondary bacterial infection Vaccination for Small Pox Vaccination was discontinued in US in 1972 Currently, about 50% of US population has not been vaccinated Antibodies last in blood stream for 5 to 15 years Polio Transmitted by water contaminated with polio victims’ feces Today children receive 4 vaccinations between ages 2 months and 4 years 1979- polio eradicated from US Who is this person? Polio total number of cases reported world-wide on May 12, 2005: 155 In the 1950, summertime was scary for parents because many children became infected with polio Symptoms of Polio -in 95% of cases, there are NO symptoms -flu -diarrhea -fever -sore throat -meningitis -paralysis Dr. Jonas Salk: developed polio vaccine in 1955 Dr. Albert Sabin developed the ORAL polio vaccine in 1957 Viruses and Plants Viruses can infect bacteria, fungi and plants as well as animals This is the Tobacco Mosaic Virus Herpes Genital warts Herpes 50-80% of American Population is infected with Herpes Simplex 1 (cold sores, mouth lesions) At least 20% of American population infected with Herpes Simplex 2 (genital herpes) NO CURE!!!!! As yet, no vaccine, but it is being studied Transmission: skin to skin contact Mouth herpes can be transmitted to a person’s genitals, and vice versa Recurrences happen about 4 times per year, and are triggered by stress, fatigue, diet, skin irritation Chicken Pox Measles Mumps