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CAPT REVIEW STRAND V Mrs. Scicchitano MARCH 2013 OBJECTIVE: Explain how meiosis contributes to the genetic variability of organisms. MITOSIS: The process of cell division that occurs in somatic cells. The new cells are genetically identical to the original cell. SOMATIC CELLS: body cells (ex. skin cells, stomach cells, muscle cells). MEIOSIS: The process of cell division that creates gamete cells. These cells are genetically different to the parent cells. GAMETE CELL: are reproductive cells produced in sex organs. Sperm are produced in the testes of males. Eggs are produced in the ovaries of females. ZYGOTE: an egg that has been fertilized by a sperm cell OFFSPRING: child •During meiosis the cells goes through division TWICE! •At the end of meiosis there are 4 daughter cells that are haploid. •The daughter cells have HALF the normal number of chromosomes. Symbolically this is known as n. Diploid Cell (2n): number of chromosomes found in somatic cells Haploid (n): number of chromosomes found in gamete cells Diploid # for humans: 46 Haploid # for humans: 23 Why do siblings look different? GENETIC VARIABILITY: Meiosis creates unique sperm and eggs that have individual characteristics. There are two ways genetic variability occurs 1. Fertilization - when a random sperm and random egg combine to form a zygote. 2. Crossing Over – when two pairs of chromosomes link together and segments of DNA are exchanged during meiosis. OBJECTIVE: Use the Punnett Square technique to predict the distribution of traits in monohybrid and dihybrid crossings. DOMINANT allele An allele (gene) that can “mask over” a recessive allele. It is represented by a CAPTIAL letter. RECESSIVE allele An allele (gene) that can only be expressed if a dominant allele is absent. It is represented by a LOWER CASE letter. Ex. “B” Ex. “b” HOMOZYGOUS (purebred) HETEROZYGOUS (hybrid) When a pair of alleles When a pair of alleles for a gene are for a gene are DIFFERENT. IDENTICAL or the SAME. Ex. BB or bb Ex. Bb GENOTYPE PHENOTYPE The description of the gene pair. The observable trait. Ex. BB, Bb, bb Ex. Brown eyes or blue eyes Genotype(s): Phenotype: Genotype: Phenotype: CROSS A HOMOZYGOUS PURPLE FLOWER WITH A WHITE FLOWER. PURPLE IS DOMINANT, WHITE IS RECESSIVE. B b b B Cross a homozygous tall (TT) and brown haired (BB) male with a recessive short (tt) and blonde (bb) female. TTBB x ttbb Co-Dominant (Multiple Alleles): A type of inheritance when two alleles are equally dominant and expressed. Ex. Blood Types There are 3 alleles for blood typing: A, B, O A and B alleles are co-dominant O allele is recessive • Even though “O” is capitalized, it is still considered a recessive allele. BLOOD TYPE GENOTYPE “A” blood AA, AO “B” blood BB, BO “AB” blood “O” blood AB OO CROSS A PARENT WITH “O” TYPE BLOOD WITH A PARENT WITH HETEROZYGOUS “B” TYPE BLOOD. SEX-LINKED: A type of inheritance where certain alleles are found only on one sex chromosome (X) Ex. color-blindness, hemophilia, werewolf syndrome CARRIER: A female that carries the recessive sex-linked allele, but does not express the trait. CROSS A COLORBLIND MALE WITH A NORMAL FEMALE. OBJECTIVE: Deduce the probable mode of inheritance of traits (ex. recessive/dominant, sex-linked) from pedigree diagrams showing phenotypes. PEDIGREE ANALYSIS Male = Female = Marriage = Sibling = AFFECTED INDIVIDUAL = Organization Rules: 1. Generations are numbered using Roman numerals, I, II, III, etc. 2. Children are placed in birth order starting from the left side. OBJECTIVE: Describe the differences between genetic disorders and infectious diseases. Disease Infectious pathogen caused disease passed from one organism to another Genetic Disease caused by a genetic inheritance HIV Human Immunodeficiency Virus Pathogen Symptoms Treatment Virus Generally symptom free for 8-9 years No cure, difficult to develop an HIV vaccine Later stages result in weak immune system and develops into AIDS. Patients take multiple drug treatments that try to stop the virus from replicating. AIDS Acquired Immunodeficiency Syndrome CAUSED BY: a virus called HIV, that attacks White Blood Cells (CD4) HOW IS HIV TRANSMITTED? Direct contact of a mucous membrane or the bloodstream with a bodily fluid containing HIV. ex: blood,semen,vaginal fluid, breast milk Why can’t we create a medicine to fight HIV? HIV replicates at a very fast rate: 10, 000, 000,000 virons per day. HIV differs from many viruses in that it has a very high mutation rate . About 1 mutation every 5 seconds. OBJECTIVES: -Explain how the processes of genetic mutation and natural selection are related to the evolution of species. -Describe how structural and behavioral adaptations increase the chances for organisms to survive in their environments. It is not the strongest of the species that survives, nor the most intelligent that survives. It is the one that is the most adaptable to change. -Charles Darwin, Origin of Species Adaptations (structural and behavioral): inherited characteristics that increases an organisms chance of survival and opportunity to reproduce in it’s niche. Birds---migrate/fly Bears---hibernate Possums---play Desert south in the winter in the winter "dead" to avoid predators animals---nocturnal/inactive during the daytime Duck---webbed feet Fish---gills Giraffe---long neck Beaver---large, pointed teeth Whale---blubber Cactus---shallow roots Snake---flexible jaw Genetic Change! Nucleotides or genes of DNA/RNA can change randomly (mutations). This can lead to a new variation of an organism, this may or may not give the organism an advantage to survive. Charles Darwin: The founder of the theory Natural Selection and author of “Origin of Species” Natural Selection: a process by which individuals that are better suited to their environment survive and reproduce most successfully 1. Overproduction – Each species produces more offspring than can survive. 2. Genetic Variation – Individuals in the population have different traits. (ex. Different fur color, size of claws, length of tail). 3. Struggle to Survive – The natural environment can not support all organisms. This can lead to competition of food, shelter & mates. 4. Reproduction: The organisms that are well adapted to their environment reproduce and pass the favorable traits to their offspring. Those who survive & reproduce are considered “the fittest”. OBJECTIVE: Explain how the current theory of evolution provides a scientific explanation for fossil records of ancient life forms. Fossil: Preserved remains or evidence of an ancient organism. How are fossils formed? An organism dies and is covered by sediments before being rotted or eaten. It will become part of the sedimentary layer that becomes rock. The lower the layer is, the older the fossil is. The higher the layer is, the younger the fossil is. OBJECTIVES: - Describe the factors that affect the carrying capacity of the environment. - Explain how change in population density is affected by emigration, immigration, birth rate and death rate, and relate these factors to the exponential growth of human populations. - Explain how technological advances have affected the size and growth rate of human populations throughout history. Exponential is growth that would take place under ideal conditions with unlimited resources. Logistical is growth that is eventually limited to a number (carrying capacity) that can be supported by environmental resources. Carrying Capacity: The number of individuals in a population that an environment can support. Exponential Growth Curve Logistical Growth Curve 1. Birth Rate: the amount of births for a given time period 2. Death Rate: the amount of deaths for a given time period 3. Immigration: movement of organisms INTO an area occupied by an existing population 4. Emigration: movement of organisms OUT of an area where population is located Definition: A graph that shows a population’s growth based on AGE and SEX. Age Groups: 1. Pre-Reproductive= 0-4 through 15-19 2. Reproductive= 20-24 through 40-44 3. Post Reproductive= 45-49 through 80+ There are 3 types of growth patterns: 1. Rapid Positive Growth 2. Slow Positive Growth 3. Negative Growth http://www.slideshare.net/lntrullin/under standing-populationpyramids?from=share_email International Database http://www.census.gov/ipc/www/idb/count ry.php