Download Inheritance Review

What do you know?
Testing the unborn
Chromosomal
disease
Genetic disease
100
100
100
200
200
200
300
300
300
400
400
400
The challenge
Testing the unborn - 100
Name the procedure that uses
a needle to withdraw fluid from
the womb to acquire cells that
can be used for a karyotype. .
Amniocentesis
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Testing the unborn - 200
Name an invasive procedure that can
be done between the 4th and 9th week of
gestation to acquire cells for a
karyotype.
Chorionic villus sampling.
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Testing the unborn - 300
• Identify the gender
of this patient.
Answer: Male, XY
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Testing the unborn - 400
List three
characteristics of
DNA that are used
to create a
karyotype
Answer:
Length of chromosome
Centromere location
Banding patterns
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Chromosomal disease- 100
Provide the notation
and its meaning for this
karyotype.
Answer: 45 X0
Missing an X
chromosome, Turner
syndrome
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Chromosomal disease- 200
Provide the
notation and its
meaning for this
karyotype.
Answer:
47 XXY
An extra X chromosome,
Klinefelter Syndrome
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Chromosomal disease- 300
Provide the notation
and its meaning for
this karyotype
Answer:
47 XX 21+
Female with Down
Syndrome
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Chromosomal disease- 400
Describe the biological
process that results in trisomy
21.
Answer:
When a new cell is forming the chromosomes do not
split equally. A new cell may have 22 or 24
chromosomes. When it pairs with a gamete that has
the correct haploid number an aneuploidy situation is
created.
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Genetic Disease - 100
Explain the
pattern of
inheritance
associated with
this pedigree.
Answer:
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Autosomal dominant.
Parents can be
heterozygous.
Genetic Disease -200
Name a disease that is autosomal
recessive.
Cystic fibrosis
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Genetic Disease - 300
How does Huntington’s disease affect a
person?
Answer: It is a brain disorder that affects their ability to
talk, think, and move.
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Genetic Disease - 400
• How can Cystic fibrosis be treated using
gene therapy?
Answer: Healthy genes are inserted into
the lungs cells. They replace the
unhealthy genes.
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The Challenge - 500
If a person has one allele for a disease
does it mean that they have symptoms
of the disease?
It depends. If it is an autosomal
dominant disease then yes. But if it is
a recessive disease then no.
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