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HC70A Winter 2006 Genetic Engineering in Medicine, Agriculture, and Law Professor Bob Goldberg Class Announcements 2/14/06 Crisis in US Science & Technology HC70AL Spring 2006 Gene Discovery Laboratory Professor Bob Goldberg M 6-8 TTh 2-6 Send Me An Email Indicating That You Would Like To Take the Lab and Have A “Real-Life” Science Experience Go To http://www.mcdb.ucla.edu/Research/Goldberg/HHMI_P rogram/hc70al.html Take-Home Exam & Oral Mid-Term Exam •Exam Out - Today •Questions Due - 3/2 •Mid-Term Oral - 3/2 •Rules & Fail Safe Discussion Tomorrow •Play -When Science Takes the Witness Stand -- DNA Testing & Criminal Cases Law School Murphy Hall Review of Last Lecture •How Do DNA & Genes Replicate? •The Double Helix •Genetic Engineering & The PCR Revolution! •Kerry Mullis & PCR - The Movie! Text Reading •Chapter 2 - Genes & Gene Activity •Chapter 4 - Proteins •Chapter 11 - Medical Biotechnology Handout Reading •The Molecular Genetics of Hemophilia** •Your Genes Your Choices •Genomes.Org - The Human Genome Project Information •Should We Make a Fuss? A Case for Social Responsibility in Science •Rising Above the Gathering Storm & Is America Flunking Science? Today •Mutations, Pedigrees, & Genetic Diversity •Genes To Proteins •The Genetic Code & Genetic Engineering •DNA vs. RNA •Gene Activity in Bacteria & Eukaryotes •One Gene-Many Proteins-Relevance to Humans & Chimps! •Yo-It’s All in the Sequences!-Modules & Genetic Engineering! •From Pedigree To Gene To Drug-A Case Study-Hemophilia