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Chemistry of Life Organic Chemistry Water • What do you think makes water so special? • Liquid at room temperature • Everyone needs it to survive, You are made of mostly water • It floats when it freezes • Covers 75% of the earth’s surface Uneven distribution of electrons results in a polar molecule Hydrogen Bond A bond formed in polar molecules Chemical Compounds in Living Things • Inorganic - Do not contain carbon – the exception is carbon dioxide – examples are: water, minerals, sand, stone, salts • Organic – carbon-containing compounds Organic Chemistry • Carbon has the ability to form covalent bonds that are strong and stable • Carbon can bond to Oxygen, Nitrogen, Phosphorus, Hydrogen, Sulfur and more Organic Chemistry Can be single, double or triple covalent bonds Can be a ring with single or double bonds or both Functional Groups • Phosphates • PO3 Polymerization • Can have chains of unlimited length (polymers) • large compounds (polymers) formed by joining together smaller compounds (monomer) Polymerization Starch Glucose Compounds of Life • • • • Proteins Carbohydrates Fats (lipids) Nucleic Acids Carbohydrates Powerful Stuff Carbohydrates Sugars and Starches • Contain Carbon, Hydrogen, and Oxygen in a 1:2:1 ratio • Simplest is Monosaccharides – simple sugars • Glucose, galactose, fructose • C6H12O6 • What makes them different is the arrangement of atoms • Sugars contain lots of energy (stored in the bonds) Dehydration Synthesis Dehydration Synthesis • 2 or more monosaccharides combine to form a larger molecule (polymerize) • Join at OH groups of each molecule. One OH from one molecule combines with the H of another. What is it called when you take the water out of something? Dehydration. • Synthesis is “Putting together”. Dehydration Synthesis is putting two molecules (in this case simple sugars) together and forming a complex molecule (in this case sugar). • Monosaccharides are put together forming Disaccharides • Table Sugar (sucrose) is a disaccharide. Hydrolysis Hydrolysis • Split apart polysaccharides • Reverse of dehydration synthesis Polysaccharides • • • • Putting together many monosaccharides Storage of sugars Starch (Plant) Glycogen (Animals) Lipids Phat! Lipids • Waxy, Oily • 3 Functions: – store energy – form membranes – chemical messengers Lipids • Fatty Acids and Glycerol = lipid • Fatty acids are long chains of hydrogen and carbon atoms with a carboxyl group at one end. • Glycerol – organic alcohol – 3C each attached to a hydroxyl group (-OH) - Triglyceride • Adding two or three fatty acids to glycerol forms many lipids. Lipids • Saturated and Unsaturated Lipids • Saturated – every carbon is attached to another carbon with a single bond – it has the maximum # of Hydrogen atoms • Unsaturated – If any of the C are bonded with a double bond, the fatty acid is unsaturated • Polyunsaturated – If the fatty acid contains several double bonds, it is polyunsaturated Lipids Arrangement Characteristics Saturated No Double Bonds Solid at room Temp From meats & dairy Unsaturated One double bond Polyunsaturated Several double bonds Liquid at room temp Cooking oils Good for you Lipids • Phospholipids – double ended molecule – one side dissolves in water the other side does not. • Forms Cell Membranes • Cholesterol is a sterol (type of lipid) – Important in cell membranes (keeps phospholipids from sticking together) • excess cholesterol is a risk factor of heart disease (clogs arteries) Proteins The meat of the matter! Amino Acids • Nitrogen containing • Polymers of amino acids Peptides • Bond that joins two amino acids is called a Peptide Bond. • Water molecule formed when peptide bond forms • What do we call this? … Dehydration Synthesis Peptide Bonds Peptide Bond Polypeptides • Polypeptide – long chain of peptides • One or more polypeptide chains, and sometimes other chemical groups, form a Protein. • Proteins are important for various reasons: – Help carry out chemical reactions – Pump small molecules out of cells – Ability of cells to move Enzymes Make it happen! Nucleic Acids Its all in the genes Nucleic Acids • RNA and DNA • Carbon, oxygen, hydrogen, nitrogen and phosphorus atoms • Polymers of nucleotides • Nucleotides are 5-carbon sugar, a phosphate group, and a nitrogenous base. • Nucleotides can be linked together to form polynucleotide. • Store and transmit genetic information Nucleic Acids Nucleic Acids