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LarreaPlus LARREAPLUS Serving Size 1 capsule Servings Per Container 90 Amount Per Serving Vitamin C (ascorbic acid) Zinc (lysinate) Bee propolis (5:1) Larrea tridentata (chaparral)(4:1) L-lysine (HCl) Olive leaf extract 150 mg 5 mg 150 mg 150 mg 150 mg 100 mg (Olea europaea)(20% oleuropein) Melissa officinalis (rosmarinic acid)(5%) 50 mg OTHER INGREDIENTS: Cellulose, silica. SUGGESTED USE: As a dietary supplement, take 1 capsule per day for immune health. For additional immune support, take 2-3 capsules two to three times per day or as directed by your healthcare professional. REFERENCES: 1. Arens M, Travis S. Zinc salts inactivate clinical isolates of herpes simplex virus in vitro. J Clin Microbiol. 2000 May;38(5):1758-62. 2. Aziz NH, Farag SE, Mousa LA, et al. Comparative antibacterial and antifungal effects of some phenolic compounds. Microbios. 1998;93(374):43-54. 3. Cho MH, Moinuddin SG, Helms GL, Hishiyama S, Eichinger D, Davin LB, Lewis NG. (+)-Larreatricin hydroxylase, an enantiospecific polyphenol oxidase from the creosote bush (Larrea tridentata). Proc Natl Acad Sci U S A. 2003 Sep 16;100(19):10641-6. 4. Fortes C, Forastiere F, Agabiti N, et al. The effect of zinc and vitamin A supplementation on immune response in an older population. J Am Geriatr Soc. 1998 Jan;46(1):19-26. continued on reverse *These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. AN INNOVATIVE FORMULA COMBINING SELECT HERBS AND EXTRACTS FOR THEIR ANTIVIRAL, ANTIOXIDANT, AND ANTI-INFLAMMATORY PROPERTIES* - Natural components with known antimicrobial and antiviral action* - Herbal anti-inflammatory* - Botanical and nutrient immune system support* - New formulation provides 4:1 extract of Larrea tridentata (600 mg equivalent)* - Contains additional antioxidant ingredients* LARREA TRIDENTATA has been in existence for over 12,000 years and has been scientifically documented as the oldest living plant on earth. To the native tribes of the Southwestern desert in the United States, it was often referred to as “medicine chest.”* Larrea tridentata’s ability to prevent virus replication, particularly against the herpes virus, caught the attention of clinicians. The herpes virus is extremely prevalent in most of the world. The herpes family of viruses is made up of approximately 80 distinct types of viruses, and it is probable that some type of herpes virus will affect nearly everyone in their lifetime.* Although the symptoms of herpes may not be obvious, new research tells us that the viruses are quite active, inflicting constant, cumulative damage to the critical organs in our bodies as they replicate at a low level throughout our lives. Because herpes viruses are excellent at evading the forces of the immune system, we have often felt defenseless against these viruses.* Larrea has demonstrated invaluable promise in the fight against numerous herpes virus conditions. Larrea’s active constituents function as powerful antioxidants that also assist in inhibiting viral replication. By stopping the invasion and survival of herpes virus in the body, further destruction of healthy cells is alleviated.* The active antiviral compounds of the larrea plant have now been formulated with other herbs and nutrients known to have antimicrobial and immunesupport action.* TEL: 425.487.0788 / 866.272.0500 FAX: 425.485.3518 www.bio-genesis.com LARREAPLUS REFERENCES: 5. Gnabre JN, Brady JN, Clanton DJ, et al. Inhibition of human immunodeficiency virus type 1 transcription and replication by DNA sequence-selective plant lignans. Proc Natl Acad Sci U S A. 1995 Nov 21;92(24):11239-43. 6. Gnabre JN, Ito Y, Ma Y, Huang RC. Isolation of anti-HIV-1 lignans from Larrea tridentata by counter-current chromatography. J Chromatogr A. 1996 Jan 8;719(2):353-64. 7. Griffith RS, Walsh DE, Myrmel KH, et al. Success of L-lysine therapy in frequently recurrent herpes simplex infection. Treatment and prophylaxis. Dermatologica. 1987;175(4):183-90. 8. Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London: The Pharmaceutical Press, 1996. 9. Thein DJ, Hurt WC. Lysine as a prophylactic agent in the treatment of recurrent herpes simplex labialis. Oral Surg Oral Med Oral Pathol. 1984 Dec;58(6):659-66. 10. Vynograd N, Vynograd I, Sosnowski Z. A comparative multi-centre study of the efficacy of propolis, acyclovir and placebo in the treatment of genital herpes (HSV). Phytomedicine. 2000 Mar;7(1):1-6. 11. Wolbling RH, Leonhardt K. Local therapy of herpes simplex with dried extract from Melissa officinalis. Phytomedicine. 1994;1:25-31. *These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. 091009 ZINC is a biologically essential trace element and a vital cofactor in many biological processes including DNA, RNA, and protein synthesis. Zinc also plays a role in immune function and wound healing. Research shows that zinc supplementation promotes cell-mediated immune response, including natural killer cells and T-lymphocyte activity. This arm of the immune system is activated during the body’s defense against viral infections. In addition, zinc has shown specific antiviral activity against the herpes virus.* PROPALIS is a resinous material from poplar and conifer buds used by bees for hive maintenance. Propalis has been used medicinally for abscesses and wound healing since 350 B.C. The potent flavanoids found in propolis exhibit antiviral, antibacterial, and antifungal activity. In addition, propolis extract has powerful antioxidant effects and suppresses inflammatory metabolism.* L-LYSINE has been reported to reduce viral replication by modulating the production of arginine. L-lysine provides nutritional support for the body’s natural defense against infections. When taken orally, L-lysine has been shown to reduce replication of the herpes virus and decrease severity and healing time.* VITAMIN C, MELISSA OFFICINALIS & OLIVE LEAF EXTRACT’s active constituents have demonstrated potent immune support and antioxidant properties. Together they provide important protection against tissue-damaging free radicals and maintain normal immune cell defenses.*