Download Company Overview - Peregrine Pharmaceuticals, Inc.

Company Overview
Leader in First-in-Class Monoclonal Antibodies Focused on the
Treatment and Diagnosis of Cancer
Our Mission
Delivering innovative and high quality biopharmaceutical products to improve patient
lives
Our Values:
- Passion: We have a deep personal drive to improve patients’ lives
- Innovation: We continuously pursue novel solutions
- Integrity: We strive to do the right thing every time and accept responsibility for our
actions
- Teamwork: We foster collaboration and work together to achieve goals
- Adaptability: We readily change to meet new challenges
About Peregrine
Peregrine Pharmaceuticals is a clinical stage biopharmaceutical company focused on
developing therapeutics to stimulate the body's immune system to fight cancer. We are
pursuing multiple clinical programs with our lead product candidate, bavituximab. Peregrine also
has in-house cGMP manufacturing capabilities through its wholly-owned subsidiary Avid
Bioservices, Inc. (www.avidbio.com), which provides development and biomanufacturing
services for both Peregrine and outside customers.
Bavituximab, in combination with other anti-cancer agents, has demonstrated promising signs of
anti-tumor activity. Bavituximab is an investigational immunotherapy designed to assist the
body's immune system by targeting and modulating the activity of phosphatidylserine (PS), a
highly immune-suppressive signaling molecule expressed broadly on the surface of tumor cells
1/2
Company Overview
and tumor blood vessel cells. PS targeting antibodies are thought to affect the
immunosuppressive environment that many tumors establish in order to proliferate and spread,
while also fighting cancer by activating immune cells that target and fight cancer. Peregrine is
working with recognized oncology leaders, including AstraZeneca (AZ), Memorial Sloane
Kettering Cancer Center (MSKCC), the National Comprehensive Cancer Network (NCCN) and
the University of Texas Southwestern Medical Center to advance its research and clinical
programs, and to capture the value that we believe exists in new bavituximab therapeutic
combinations and indications. For more information about bavituximab, click here . For more
information on antibody mediated blockade of the phosphatidylserine (PS) signaling pathway,
click here
.
In addition to drug development, Peregrine’s wholly-owned subsidiary, Avid Bioservices, is a
growing commercial biomanufacturing business that provides a comprehensive range of
process development, high quality cGMP clinical and commercial manufacturing services for
Peregrine and other biotechnology and biopharmaceutical companies. With over 15 years of
experience producing monoclonal antibodies and recombinant proteins in batch, fed-batch and
perfusion modes, Avid's services include cGMP clinical and commercial product manufacturing
utilizing stainless steel and single use technology, purification, bulk packaging, stability testing
and regulatory strategy, submission and support. The company also provides a variety of
process development activities, including cell line development and optimization, cell culture
and feed optimization, analytical methods development and product characterization. For more
information about Avid, please visit www.avidbio.com .
2/2