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Transcript
Programmed cell death, autophagy, autohagic cell death, and apoptosis
(Lockshin RA)
Molecular mechanism of autophagy in Yeast (Ohsumi Y)
Autophagy and apoptosis represent alternative cellular responses to bioenergetic
stress.
Membrane dynamics of autophagy
1. machinery of autophagy-related pathways (Klionsky DJ)
2. autophagic degradation in the lysosome (Eskelinen EL)
3. New insights into molecular mechanisms of the canonical and specialized
autophagy (Yoshimori T)
4. Regulation of autophagy in Yeast and Mammals (Elazar Z)
5. Genetic interactions between Drosophila Atg1 and paxillin reveal a role for
paxillin in autophagy (Thomas SM)
Autophagy Workshop
6. Photoactivatable proteins reveals stress-dependent turnover kinetics of
autophagosomes (Gauket DW)
7. Characterization of regulated organelle Turnover by autophagy (Kraft C)
8. Identification of two EH domain containing Yeast proteins involved in autophagy
(Bugnicourt A)
9. Roles of Atg26 in methanol-induced autophagy and plant pathogenecity (Sakai Y)
10. The regulation and function of Drosophila Atg1 in autophagy (Chang YY)
11. Determining the role of the Drosophila Bcl-2 protein, Buffy, in mediating
autophagy (Menserrate JP)
12. HIF-1a is a hypoxia-dependent regulator of autophagy (Lum JJ)
Regulation and physiology of autophagy
13. Signaling control of macroautophagy (Codogno P)
14. TOR signaling pathway and control of autophagy in Drosophila (Neufeld T)
15. Physiological role of autophagy in protein metabolism in mice (Mizushima N)
16. Foxo3 stimulates autophagy in atrophying muscle (Zhao J)
Specific autophagy and organelle degradation
17. Role of Atg30 in selective peroxisome turnover in Pichia pastoris (Subramani S)
18. Mitochondrial autophagy (Mitophagy) in living hepatocytes (Lemasters J)
19. Chaperone-mediated autophagy (CMA, Cuervo AM)
20. Role of autophagy in the degradation of Polyglutamine aggregates (Kopito RR)
21. Autophagy counterbalances Endoplasmic Reticulum expansion during the
unfolded protein response (Schuck S)
How to differentiate apoptosis vs necrosis vs autophagic cell death
experimentally
22. biochemical and light microscopic detection of autophagosome formation and
autophagic degradation (Mizushima N)
23. Electron microscopic detection of autophagy (Eskelinen EL)
24. Autophagic cell death: does autophagy have a license to kill? (Codogno P)
25. So many ways to die: elucidating the mechanism by which DT-IL3 kills acute
myelogenous leukemia cells (Horita HN)
26. System approach to quantifying cell death mechanism in stress response
(Sokhansanj BA)
27. System level analysis of the cell death network by single and double RNAimediated perturbations (Zalckvar E)
Interaction of apoptosis and autophagy pathways
28. role of autophagy in caspase-independent cell death (Lenardo MJ)
29. System level analysis of programmed cell death: switching between apoptosis,
autophagy and necrosis (Kimchi A)
30. The intricate interplay between apoptosis and autophagy (Kroemer G)
31. Crystal structure of the BclxL-beclin1 peptide complex: beclin 1 is a novel BH3
only protein
Autophagy in immunity and infection
32. Role of autophagy in viral antigen presentation by class II MHC molecules
(Levine B)
33. Autophagy as an immune effector in tuberculosis and HIV (Deretic V)
34. Subversion of cellular autophagosomal machinery by RNA viruses (Kirkegarrd
K)
35. Autophagy is involved in CD4 T cell apoptosis
36. Contribution of the autophagosomal compartment in the presentation of
endogenous HSV-1 viral antigens on MHC class I molecules (English L)
Autophagy as a target in cancer therapy
37. Treatment of malignant gliomas with manipulation of autophagy (Kondo S)
38. UVRAG, autophagy and cancer (Jung JU)
39. Autophagy, metabolic stress and genomic instability (jin SV)
40. Regulation of autophagy-dependent cell death and tumorigenesis by endophilin
B1/Bif1 (Takahashi Y)
Autophagy in cell survival and cell death
41. Role of autophagy in cancer (White E)
42. Novel connections between autophagy and apoptosis (Levine B)
43. Autophagic cell death in Drosophila (Baehrecke EH)
44. Functional characterization of human Atg4D: processing of Atg8 homologues and
regulation by caspases (Betin VMS)
45. Inhibition of integrin-mediated crosstalk with EGFR/Erk or Src signaling
pathways in autophagic prostate epithelial cells induces caspase-independent
death (Miranti CK)
46. The novel autophagy regulator Ambra-1 is required for nervous system
development)
Autophagy in cell death and disease
47. Common regulators of apoptosis and autophagy-an analysis of known cell death
genes in starvation-induced autophagy (Hou CYC)
48. Kringle 5 of human plasminogen, an angiogenesis inhibitor, induces both
autophagy and apoptotic death in endothelial cells (Nguyen TMB)
49. Ubiquitinated-protein aggregates form in pancreatic b-cells during diabetesinduced oxidative stress and are regulated by autophagy (Brumell JH)
50. Selective autophagy regulates formation of intracytoplasmic inclusions (Komatsu
M)
51. Autophagy attenuates CryAB(R120G)-induced desmin-related cardiomyopathy
(Tannous P)
52. Autophagy kisses NF-kB to death without Hsp90 chaperoning (Xiao G)
53. A critical role for the autophagy gene Atg5 in T cell survival and proliferation
(Pua HH)
54. TLR ligands control induction of autophagy in macropahges (Vargas MAD)
Autophagy as a therapeutic target in neurodegenerative diseases
55. Autophagic clearance of aggregate-prone proteins: therapeutic implications
(Rubinstein DC)
56. Autopahgy deficiency in Alzheimer’s disease and Neurodegeneration (WyssCoray T)
57. Macroautophagy failure in Alzhermer’s disease: genetic factors and pathological
consequences (Nixon RA)
58. Decreased insulin-receptor signaling promotes the autophagic degradation of bamyloid peptide in C.elegans (Florez-McClure M)