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Pre-Lecture Quiz, Chapter 52, Drug Therapy for Seizure Disorders and Spasticity True/False 1. Oral doses of phenobarbital must be given with food. 2. Topiramate (Topamax) may be used as monotherapy in the treatment of primary generalized tonic–clonic seizures. 3. Baclofen and diazepam decrease the effects of gamma-aminobutyric acid (GABA). 4. Cyclobenzaprine hydrochloride (Flexeril) is used to treat muscle spasms. 5. Dantrolene (Dantrium) is the only centrally acting muscle relaxant. Fill in the Blank 1. __________ feedings may cause a decrease in levels of phenytoin. 2. Intravenous __________ is the drug of choice for rapid control of tonic–clonic seizures. 3. Patients receiving hydantoin (Dilantin) should be assessed for __________ hyperplasia. 4. Baclofen (Lioresal) is an agonist-specific __________ of GABA receptors in the spinal cord. 5. Centrally acting muscle relaxants may be used to treat and prevent __________ hyperthermia.