Download Slide () - Neurology Collection

The major serotonergic systems in the brain arise in the raphe nuclei of the brain stem. Serotonin is synthesized in a group of brain stem nuclei called the
raphe nuclei. These neurons project throughout the neuraxis, ranging from the forebrain to the spinal cord. The serotonergic projections are the most
massive and diffuse of the monoaminergic systems, with single serotonergic neurons innervating hundreds of target neurons. (Adapted, with permission,
from Heimer 1995.)
A. A sagittal view of the brain illustrates the raphe nuclei. In the brain these nuclei form a fairly continuous collection of cell groups close to the midline of
the brain stem
and extending
its and
length.
In thePrinciples
drawing here
they Science,
are shown
in Editon
more distinct rostral and caudal groups. The rostral raphe nuclei
Source:
Disorders along
of Mood
Anxiety,
of Neural
Fifth
project to a large number of forebrain structures.
Citation: Kandel ER, Schwartz JH, Jessell TM, Siegelbaum SA, Hudspeth AJ, Mack S. Principles of Neural Science, Fifth Editon; 2012 Available
B. This coronal view
the brain illustrates some
of the May
major14,
structures
at: of
http://mhmedical.com/
Accessed:
2017 innervated by serotonergic neurons of the raphe nuclei.
Copyright © 2017 McGraw-Hill Education. All rights reserved