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TEST BANK MULTIPLE CHOICE 1. _____________ is popular among drug enthusiasts, and some users snort heroin and smoke crack in combination. a. drug crossing b. criss-crossing c. drug spiking d. potentiating ANS: B 2. REF: 34 LO: 3 The __________ acts as a gatekeeper to prevent certain substances from entering brain tissue. a. hypothalamus b. medial forebrain bundle c. blood-brain barrier d. amygdala ANS: C 4. LO: 2 In reaction to emotional memories burned into it by the intensity of the drug euphoria, the __________ operates outside of conscious control to cause intense cravings. a. hypothalamus b. medial forebrain bundle c. blood-brain barrier d. amygdala ANS: D 3. REF: 31 REF: 31-32 LO: 1 The _________________ controls such basic drives as sexual activity. a. hypothalamus b. medial forebrain bundle c. blood-brain barrier d. amygdala ANS: A REF: 34 LO: 3 19 Test Bank 5. Neurotransmitter levels are controlled by chemicals in the presynaptic terminal which are known as _________. a. agonists b. catecholamines c. monoamine oxidases (MAO) d. antagonists ANS: C 6. LO: 1 REF: 23 LO: 1 The term kindling is an alternative term for __________. a. reverse tolerance b. sensitization c. tolerance d. selective tolerance ANS: A 9. REF: 27 One of the last parts of the brain to mature deals with the ability to _______________.. a. make sound judgments b. control movement c. communicate d. all of the above ANS: A 8. LO: 1 Substances that stimulate receptor sites are known as __________. a. agonists b. catecholamines c. monoamine oxidases (MAO) d. antagonists ANS: A 7. REF: 27 REF: 33 LO: 3 Increased sensitivity to the same or lesser dosage of a drug over time is known as _____. a. reverse tolerance b. sensitization c. tolerance d. selective tolerance ANS: A REF: 33 LO: 3 20 Chapter 2: The Biology of Psychoactive Substances 10. When determining risk versus reward, the _______________ tends to emphasize benefits while discounting dangers. a. adult brain b. adolescent neurons c. adolescent brain d. adult neurons ANS: C 11. LO: 1 REF: 34 LO: 3 A ___________ is the basic working unit of the central nervous system. a. neuron b. cell body c. synapsis d. neurotransmitter ANS: A 14. REF: 31 Brain imaging and other technologies show that the addicted brain is _____________ from the nonaddictive brain. a. somewhat different b. not different c. distinctly different d. comparatively different ANS: C 13. LO: 1 Psychoactive drugs are absorbed into the bloodstream and quickly carried to the _______ nervous system. a. central b. autonomic c. sympathetic d. parasympathetic ANS: A 12. REF: 24 REF: 24 LO: 1 __________ where neurotransmitters attach cause chemical substances to interact and produce pharmacological actions. a. Transmitting neurons b. Axon terminals c. Receptor sites d. Receiving neurons ANS: C REF: 27 LO: 1 21 Test Bank 15. An important part of the cell body are __________, which appear as branches of a tree and receive messages from other neurons. a. Serotonin b. Norepinephrine c. Dendrites d. Dopamine ANS: C 16. LO: 1 REF: 26 LO: 1 Depending on the type of _______________, electrical charges from the adjoining neuron are either inhibited or enhanced. a. neurotransmitter b. neuron c. drug d. drug cues ANS: A 19. REF: 27 __________ activates nerve cell receptors to stimulate pleasurable feelings. a. Serotonin b. Norepinephrine c. Dendrites d. Dopamine ANS: D 18. LO: 1 Neurotransmitters are broken down by MAO or recycled by the sending neuron in a process called ______________. a. reuptake b. transportation c. homeoestase d. synthesis ANS: A 17. REF: 24 REF: 27 LO: 1 ___________, one of about 100 neurotransmitters found in the central nervous system, has received special attention because of its apparent role in the regulation of mood and affect and because of its role in motivation and reward processes. a. Serotonin b. Norepinephrine c. Dendrites d. Dopamine ANS: D REF: 26 LO: 1 22 Chapter 2: The Biology of Psychoactive Substances 20. The National Institute on Drug Abuse reports that infants who are born to heroin-abusing mothers frequently suffer from ________________________. a. neonatal adaptation syndrome b. neonatal abstinence syndrome c. neonatal disability syndrome d. neonatal syndrome of polyendocrinopathy ANS: B 21. LO: 1 REF: 24 LO: 1 Many, if not most, people who have been exposed to ____________ or heroin, for example, find the initial experience distinctly unpleasant. a. morphine b. benzodiazepine c. cocaine d. serotonin ANS: A 24. REF: 26 __________, a part of neurons, are contact points for communication between neurons. a. Transporters b. Synapses c. Receptors d. Neurotransmitters ANS: B 23. LO: 4 __________ trigger activity by moving across the synaptic gap to receptor sites on the dendrites on the other side. a. Transporters b. Synapses c. Receptors d. Neurotransmitters ANS: D 22. REF: 35 REF: 28 LO: 1 Consuming more than one type of psychoactive chemical is called _________. a. multidrug use b. criss-crossing c. polydrug use d. additive effects ANS: C REF: 30 LO: 2 23 Test Bank TRUE/FALSE 1. The greater the half-life of a drug, the more severe the withdrawal symptoms after use of the drug is discontinued. ANS: F 2. REF: 33 LO: 3 REF: 24 LO: 1 REF: 34 LO: 3 REF: 33 LO: 3 Homeostasis is a state of equilibrium achieved through the self-adjusting characteristics of the body. ANS: T 10. LO: 1 Selective tolerance is also referred to as kindling. ANS: F 9. REF: 27 The hypothalamus regulates the release of hormones from the pituitary gland. ANS: T 8. LO: 2 Neurons do not interlock but instead are separated by synapses. ANS: T 7. REF: 30 The continued use of certain drugs, particularly depressants, can produce tolerance. ANS: T 6. LO: 4 Reuptake is the sending neuron’s process of recycling neurotransmitters. ANS: T 5. REF: 35 Catecholamine, dopamine, norepinephrine, and endorphins are examples of polydrugs. ANS: F 4. LO: 2 Cocaine use by pregnant women has been linked to various abnormalities in their infants because the substance reduces the supply of blood and oxygen to the fetus. ANS: T 3. REF: 32 REF: 33 LO: 3 A neuron consists of a cell body (soma), the axon, synapses, and dendrites. ANS: T REF: 24 LO: 1 24 Chapter 2: The Biology of Psychoactive Substances COMPLETION 1. __________ is the basic building block for the advancement of human knowledge. ANS: Theory 2. LO: 1 REF: 28 LO: 1 REF: 30 LO: 2 REF: 33 LO: 3 Children born to __________-addicted mothers, in addition to having a host of other physical problems, such as small size, anemia, heart disease, hepatitis, and pneumonia, also suffer from withdrawal symptoms. ANS: heroin 9. REF: 27 ____________develops as the body becomes progressively immune to the chemical effects of the drug at the cellular level. ANS: Tolerance 8. LO: 1 Understanding the biology of psychoactive drugs is complicated by the phenomenon of _______ use—abusers consuming more than one type of psychoactive chemical. ANS: polydrug 7. REF: 25 The __________ model emphasizes the involuntary nature of drug use—use based on a craving—that has found support in laboratory experiments with animals. ANS: disease 6. LO: 1 With regular drug use, ___________ become less responsive to drugs that stimulate them. ANS: receptors 5. REF: 27 A cell body is also called a __________. ANS: soma 4. LO: 1 Neurotransmitter level is controlled by chemicals in presynaptic terminals known as ______________________ (MAO) and transporters that recycle them for further use. ANS: monoamine oxidases 3. REF: 28 REF: 35 LO: 4 ___________ use by pregnant women has been linked to serious emotional difficulties in children which can hinder their social and psychological development. ANS: Cocaine REF: 35 25 LO: 4 Test Bank 10. The neurological effects of mixing drugs can be additive, synergistic, potentiating, or _______________. . ANS: antagonistic REF: 31 LO: ESSAY 1. Explain the three ways in which drugs can enter the bloodstream. ANS: N/A 2. LO: 3 REF: 33 LO 3 Explain the additive, synergistic, potentiating, and antagonistic neurological effects of mixing drugs. ANS: N/A 5. REF: 33 Explain the concept of reverse tolerance. ANS: N/A 4. LO: 1 Explain homeostasis. ANS: N/A 3. REF: 32 REF: 31 LO: 2 What are the symptoms of children who were born with fetal alcohol spectrum disorder? ANS: N/A REF: 36-37 LO: 4 26