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DNA Replication and Cell Division Notes __________ ___________- series of events during which the cell grows, replicates its DNA and divides to form two daughter cells, each of which begin the cycle again. Chromosome Structure chromatids- each contains the DNA double helix inside centromere Terms to Know: ____________________: structures containing the DNA and they help pass this genetic info from one generation to the next; they’re usually visible as an ___ _______________ during _____ _______________ ____________________: identical “sister” structures of the replicated chromosomes; each chromatid contains a double helix _____ and chromatids _______________ from each other during cell division ____________________: area that attaches each pair of chromatids _______________; usually located near the _______________ of the chromatids ____________________: structure of DNA tightly coiled around histones proteins and appear as a mass of threadlike material when cell is not dividing ____________________paired structures found in _____________ cells which help __________ chromosomes during __________ Different levels of DNA condensation during Cell Cycle 2 1. DNA double helix 2. Chromatin (DNA around histones) 3. Condensed chromatin with centromere visible 4. Chromatin with replicated DNA & centromere 5. Chromosome “X” structure Terms Continued… _______________: (n) having a single set of chromosomes in the cell. ex. __________; humans have 23 chromosomes in sex cells (egg and sperm cells) _______________: (2n) having two sets of homologous chromosome in the cell. ex. Somatic (__________) cells; humans have 23 pairs or 46 chromosomes in body cells It’s all about the chromosomes! – There are _____ chromosomes in the human body cells – The __________of chromosomes remain constant during __________-division of the ______ Why Do Cells Divide? Maintain workable _______________ __________ to ______________ - too big-can’t work!! Replace damaged cells; _______________ Produce __________ __________ Increase in __________ and for __________ • • • • Cell ____________________, making of more cells or making offspring, can be ____________ (offspring produced from _____ parent) or sexual (union of _____ parental cells) Forms of Asexual Reproduction (one parent) • __________ __________-cell division in bacteria whereby one parent splits into two cells • __________-cell division in yeast (fungi) whereby daughter cell protrudes (buds) from parent • _______________ Propagation- production of new plant structures without seed or spore formation • _______________ ability to recreate lost or damaged body parts, tissue or cells Advantages of Asexual Reproduction • • • __________production of offspring (bacteria) ___________________ of body parts _______________ ____________________ are continually passed on DNA Replication • • Before a cell can divide the DNA must _______________ (make a copy of itself) Replication Steps… 1. DNA __________ • • An _______________unzips the molecule The enzymes break the hydrogen bonds that hold the nitrogen bases together. 2. Base Pairing • _____________________ bases match with each DNA strand on the open helix 3. DNA Zips Up • An enzyme zips the new molecules back up. • _____ _______________ strands of DNA! • Now that DNA has replicated, we are ready to begin __________ (__________ of the cell divides) Phases of Mitosis- Name each phase shown in the diagrams below: 1. 3. 5. 2. 4. Cytokinesis- division of the _______________ ________ Cells: In plant cells, cytokinesis occurs by the formation of a ________ __________. The cell plate is a new cell ________ assembled from the inside of the dividing cell outward. ___________ Cells:In animals, cytokinesis occurs by the formation of a ____________ furrow. The cleavage furrow forms from the outside inward. Microfilaments (part of the cytoskeleton) pull the cell _____________ from each end inward. When the cell membranes meet, the cell splits in half. Mitosis Review 1. Is the beginning parent cell diploid or haploid (2n or n)? 2. Are the daughter cells diploid or haploid (2n or n)? 3. How many daughter cells are produced? 4. Are the resulting daughter cells different from the parent cell? 5. Are the resulting daughter cells different from each other? 6. How many chromosomes are in a human body cell? 7. Are the chromosomes in human body cells identical? 8. What types of cells are produced by mitosis? 9. Why (when) does a cell go through mitosis? 10. How is cytokinesis different in plant and animal cells?