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Genetics: The Science of Heredity Table of Contents What Is Heredity? Probability and Heredity Patterns of Inheritance Chromosomes and Inheritance Learning Goal Develop and use a model to describe why asexual reproduction results in offspring with identical genetic information and sexual reproduction results in offspring with genetic variation. Big Question Why don’t offspring always look like their parents? Discuss…. Lesson 1 Vocabulary Lesson 1 Definition heredity Passing of physical characteristics (traits) from parent to offspring trait A specific characteristic genetics The scientific study of heredity fertilization A new organism begins when an egg and a sperm join in this process purebred When an organism is the offspring of many generations that have the same form of a trait. gene Factors to control a trait allele The different forms of a gene dominant allele One whose trait always shows up if the allele is present. Recessive allele This allele is hidden if the dominant allele is present. hybrid An organism that has two different alleles for a trait. Almost Forgotten Read Almost Forgotten and answer the question. (Be prepared to share…) Share Read What did Mendel Observe? As a priest in a monastery Mendel had little opportunity to come in contact with scientists. Ironically, his work was rediscovered by three scientists working independently in the same year. Why is it important for scientists to do library research before lab research? Family Resemblances Have you ever wondered why some family members look very similar while others look very different? Share Lab Zone Do the Inquiry Warm-Up What Does the Father Look Like? Share answer to #4. Read Mendel’s Experiments Why is it necessary to cut off the stamens of the pea flower? To make sure the pollen that landed on the pistil came from the plant Mendel wanted to use in the cross. What Is Heredity? Crossing Pea Plants Mendel devised a way to cross-pollinate pea plants. Purebred Organisms Every living thing has traits it inherited from its parents. Until the work of Mendel, people did not understand how traits were passed on from parents to offspring. What is a purebred organism? The offspring of many generations that have the same form of the trait. Read The F1 and F2 Offspring and Experiments With Other Traits and complete the chart. Mendel began each experiment plants that differed in one specific trait. What did Mendel find when he crossed purebred tall plants with purebred short plants? The offspring were all tall. Was the trait for shortness lost? No, when Mendel crossed the offspring, or F1 generation, with one another, some of the offspring were short, so the trait wasn’t lost. Are the plants in the F1 generation purebred plants? No, they were not all identical to the parent plants. Mendel did not always get exactly three-fourths and one-fourth, but the results were close enough to recognize a pattern. What could be a reason why there might be a slight variation. Some plants might have died or seeds not germinated. probability Latin Origins The terms F1 and F2 are derived from the Latin words filius and filia. In Mendel’s time an educated person would have studies Latin and Greek. In addition, his training as a monk would have included studying Latin. What other reasons might there be for using Latin terms in science? It could be a universal language. Other scientists probably studied Latin in other countries. Where else in your study of science have you seen words that are derived from Latin? Names of the elements. What Is Heredity? Results of a Cross In Mendel’s crosses, some forms of a trait were hidden in one generation but reappeared in the next. What was surprising about the offspring in the F2 generation? Read How Do Alleles Affect Inheritance? An organism’s alleles come from it’s parents. What are two kinds of alleles? Dominant and Recessive How are they different? The dominant one is the one whose trait is always seen if the trait is present. The recessive allele is hidden whenever the dominant is present. Why were purebred pea plants so important for Mendel’s experiments? Purebred plants have two identical alleles for a gene. Therefore, in a cross, each parent contributes a known allele, making the pattern of inheritance easier to detect. What Is Heredity? Alleles in Pea Plants Mendel studied the inheritance of seven different traits in pea plants. Look at Figure 3 Remember that the traits that Mendel studied have two distinct forms. Look at the seed shape. What are the two kinds of seed shape? Round or Wrinkled What trait is the dominant allele? Round What combinations of alleles will produce round seeds? Two dominant alleles or one dominant and one recessive. Are you confused? Trait refers to the general characteristic. Example- hair color Allele refers to the specific forms the characteristic can have. Example – blonde or brown “We Have It So It Must Be Dominant” Worksheet – work with a partner Use tally marks to add your info to this chart. Trait Dimples Earlobes Mid-digit hair Forelock Pinky Thumbs Dominant Class Total Recessive Class Total Assess Yourself Rate yourself on the Learning Goal Where do you stand? 1,2,3,4. Be honest. Read Allele’s in Mendel’s Crosses and Symbols for Alleles Look at Figure 4 – Remember that when you write alleles you list the dominant letter first. How would you write the alleles for a plant that is purebred tall? TT How would you write the alleles for the offspring of a cross between a purebred tall and a purebred short? Tt What term did Mendel use for the individual with one dominant allele and one recessive allele? Hybrid What Is Heredity? Dominant and Recessive Alleles What are the symbols and descriptions of allele? Use the word bank to complete the statements. What are the two possible ways the F2 offspring could look? Lab Zone Inferring the Parent Generation Corn Quick Lab – Examine an ear of colored corn to determine the alleles of the parent generation. Complete and turn in lab. Genetics Packet – Finish for Homework No Traits Lost Remember that Mendel was the first person to show that traits are inherited as discrete units that do not get lost or modified as they are passed from one generation to the next. Why do some of the offspring of two hybrid individuals show the recessive form of the trait? The hybrid parents each had one of the recessive genes. If an offspring receives both of these recessive genes, it will show the recessive form of the trait. Predict When you predict, you use evidence and prior experience to make an inference about a future event. A prediction is more than a guess. Key Concept Summary Key Concept Summary Chapter 6 Lesson 2 Probability and Heredity Read My Planet Diary p. 204 - Storm on the Way Have you ever followed a developing storm on the news? Do Weather forecasters guess about the weather? No they rely on data and past experience. What kind of evidence do scientists studying genetics rely on? Experience from crosses they have done. Vocabulary Homozygous and Heterozygous “Homo” means the same and “Hetero” means other or different. An individual who is ….. homozygous has two of the same alleles for a trait or purebred heterozygous has two different alleles for a trait or hybrid Lesson 2 Vocabulary Lesson 2 Definition probability A number that describes how likely an event will occur. Punnett square A chart that shows the possible ways alleles can combine in a genetic cross. phenotype Physical appearance or visible traits genotype An organism’s genetic makeup homozygous An organism with two identical alleles for a trait. heterozygous An organism that has two different alleles for a trait. Probability Have you ever used a coin toss to decide an issue? Why did you toss a coin in this situation? It is the fairest way to make a decision. Why is a coin toss fair? Each person has a 50-50 chance of winning. Mendel used the principles of probability to explain his results. Probability Read p. 205 What is probability? A number that describes how likely it is that an event will occur. Probability Does probability predict what will definitely occur? No, it predicts what is likely to occur. What does probability predict will happen if you toss a coin 10 times? The coin will land on heads 5 times and tails 5 times. Probability Do the Math p. 205 Read p. 206 and 207 Probability The alleles an offspring receives from it’s parents depends on probability. How is this similar to a coin toss? The allele passed on from a parent to offspring is based on probability and whether a coin lands on heads or tails is also probability. What tool can be used to predict the results of a cross? Punnett Square Probability What is a punnett square? A punnett square is a chart that shows all the possible combinations that can result from a genetic cross. Probability and Heredity How to Make a Punnett Square What are the steps in using a Punnett Square to find the probabilities of a genetic cross? Probability Draw a punnett square for a cross between a purebred pea plant with purple flowers (PP) and a purebred pea plant with white flowers (pp). Where do you write the alleles of the parents? Outside the boxes. What are the alleles for the offspring? All Pp What color flowers will the offspring have? Purple Fertilization The punnett square represents the process of reproduction. What is fertilization? The joining of two sex cells. The letters we write outside the box represent the parents sex cells. The letters inside the boxes represent the joining of the two sex cells during fertilization. Punnett Squares Punnett Square Practice – use worksheet to complete punnett squares. Phenotypes and Genotypes Read p. 208 What is an organism’s phenotype? It’s physical appearance – what it looks like. What is an organism’s genotype? It’s genetic makeup or alleles. Phenotype and Genotype Review. What is the term used to describe an organism whose genotype consists of two identical alleles for a trait? Homozygous What is the term used to describe and organism whose genotype consists of two different alleles for a trait? Heretozygous Homozygous or Heterozygous What are the two ways and organism can be homozygous for a trait? Homozygous dominant or homozygous recessive. What term did Mendel use to describe an organism that is heterozygous? Hybrid Why can you be certain of the genotype of an organism that shows a recessive trait? It must be homozygous recessive because the recessive allele is not hidden by a dominant allele. Probability and Heredity Describing Inheritance An organism’s phenotype is its physical appearance. Its genotype is its genetic makeup. Complete the missing information in the table. Probability and Heredity How do the smooth pods differ? Can you tell the genotype of the parents that produced these pods? No Why can you be certain of the plant that produced the pinched pod? The pinched pod is recessive so the the plant that produced this pod must be ss for this trait. Probability and Heredity This graph shows the phenotypes of guinea pig pups. What would be a good title for the graph? Chapter 6 Lesson 3 Patterns of Inheritance Read p. 210 My Planet Diary (Cold, With a Chance of Males) The laws of probability apply to situations that are not affected by anything other than chance. In most animal species the probability of being a male or female is 50 percent. But…in turtles and some other reptiles the environment is a deciding factor. Patterns of Inheritance Complete Inquiry Warm-Up as a group and report your tally on the chart. Patterns of Inheritance Incomplete Dominance and Codominance The traits we have seen so far have all been traits that involve two possible alleles. There are patterns of inheritance that are more complex and most traits are the result of these more complex patterns. Read p. 211 What are two of the patterns of inheritance? Incomplete dominance and codominance Incomplete Dominance and Codominance Which alleles are expressed in these offspring? both Which organism shows incomplete dominance? Which organism shows codominance? Lesson 3 Vocabulary Lesson 3 Definition Incomplete dominance When one allele is only partially dominant Codominance When both alleles are expressed equally Multiple alleles Polygenic inheritance There are three or more possible alleles for the trait Occurs when more than one gene affects a trait. Multiple Alleles Read p. 212 In multiple alleles each individual has only two alleles for each trait. Each of the rabbits shown has two alleles for coat color. The brown is the wild type or agouti The gray is called chinchilla The white is an albino The albino genotype is cc. Is cc homozygous dominant, homozygous recessive or heterozygous recessive? Homozygous recessive Patterns of Inheritance Blingwings An imaginary insect called the blingwing has three alleles for wing color: R (red), B (blue), and Y (yellow). What are the possible allele pairs for wing color in the blingwings? RY, RR, BB, BY, YY Polygenic Inheritance One gene with two possible alleles can produce three genotypes. Ex. AA, Aa,aa Two genes with two possible alleles can produce nine genotypes. Can we figure out the possible genotypes using the letters A,a,B,b? AABB, AABb, AAbb, AaBb, AaBB, Aabb, aaBB, aaBb, aabb How Genes and the Environment Interact Read p. 213 and 214 and 215 Complete bookwork. No one is born knowing how to do everything! As we live and learn we acquire traits and skills. How Genes and the Environment Interact Patterns of Inheritance An individual’s phenotype is the result of the interaction of genes and the environment. What are some traits that people inherit? Hair color, height, eye color What inheritance pattern does height show? Polygenic inheritance How might the environment affect how the genotype is expressed? A person on a poor diet may not grow to his/her full height. Genes and the Environment How do people change the phenotype of their hair? Straighten, color, curl Do these changes affect a person’s genotype? No How do you know? The body still produces the hair according to the genotype. Lesson 4 Chromosomes and Inheritance Read My Planet Diary p. 216 Genetic research has yielded information about many genetic disorders. By studying how genes are related to an inherited disorder, scientists can learn to diagnose the condition early and help the patient reduce its effects. Inquiry Warm-Up Read and complete inquiry Warm-Up What is the genotype of the offspring? Gg What is the phenotype of the offspring? Green Lesson 4 Chromosomes and Inheritance Read p. 217 What was Sutton trying to understand? How sex cells form What aspect of sex cell formation was he studying? How chromosomes move What was his hypothesis? Chromosomes are involved in how traits are passed from parents to offspring Lesson 4 Chromosomes and Inheritance Apply It! Humans have 46 chromosomes. Skunks have 50 Shrimp have 90 A netted adder's-tongue fern has more than 1200 ?????? Lesson 4 Chromosomes and Inheritance Read and Complete p. 218 Genes are carried on the chromosomes. What did Sutton observe about the relative number of chromosomes in the body cells and sex cells of grasshoppers. The sex cells have half the number of chromosomes as body cells. How are genes passed from parent to offspring? Sex cells contain half of each parent’s chromosomes, which include the parent’s genes. When sex cells join during fertilization, the offspring receive a full set of chromosomes. Lesson 4 Chromosomes and Inheritance What is the chromosome theory of inheritance? Genes are carried from parent to offspring on chromosomes. If human body cells have 46 chromosomes, how many chromosomes do human sex cells have? 23 Chromosomes and Inheritance Paired Up Sutton studied grasshopper cells through a microscope. He concluded that genes are carried on chromosomes. Lesson 4 Chromosomes and Inheritance Look at figure 1. How many chromosomes are in the body cells of a grasshopper? 24 How many chromosomes are in a grasshopper egg cell? 12 How many chromosomes are in a grasshopper sperm cell? 12 How is the chromosome number returned to normal? When a sperm and egg join together in fertilization , their individual 12 chromosomes add up to 24 chromosomes. Lesson 4 Chromosomes and Inheritance Key Concept According to the chromosome theory of inheritance, genes pass from parents to their offspring on chromosomes. A Line Up of Genes Read p. 219 Look at Figure 2 Heterozygous and homozygous apply to the individual pairs of genes not the chromosomes. Individuals can be homozygous for one trait and heterozygous for another. This leads to variety in offspring. Write the genotype for this individual AabbCcDdEEFFGg Chromosomes and Inheritance A Pair of Chromosomes Chromosomes in a pair may have different alleles for some genes and the same alleles for others. Is the organism homozygous or heterozygous? Lesson 4 Vocabulary Lesson 4 Meiosis Definition Is the process by which the number of chromosomes is reduced by half as sex cells form. What Happens During Meiosis Read p. 220 What kind of cells are produced in meiosis? Sex cells How many divisions take place during meiosis? Two What happens in the first division? Chromosome pairs line up together and then move apart What happens in the second division? Chromosomes split into identical halves, which move to new cells In which division is the number of chromosomes reduced by half? In the first division What Happens During Meiosis? Look at Figure 3 How would you describe the shape of a chromosome? Like an X What are the two sides of the X? The chromatids What holds the chromatids together? Centromere How do the chromatids of a chromosome compare? They are identical When do the chromatids separate? During the second division Chromosomes and Inheritance Meiosis During meiosis, a cell produces sex cells with half the number of chromosomes.