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Name: _____________________________________ Date: __________ Period: ____ Chapter 12: Checkpoint Questions Cardiovascular System—The Heart 1. Describe the basic function of the cardiovascular system. The cardiovascular system provides an internal transport system for blood, nutrients, and waste products. 2. Compare and contrast the structure and functions of arteries, capillaries, and veins. Arteries, capillaries and veins are all blood vessels within the body. Arteries are efferent vessels that carry blood (usually oxygenated) away from the heart. Veins are afferent vessels that carry blood (usually deoxygenated) toward the heart. Capillaries are the smallest, thin walled blood vessels that carry out nutrient exchange via diffusion across the membranes. They create a network between arteries and veins. 3. Compare and contrast the pulmonary and systemic circuits of the cardiovascular system. The pulmonary circuit pumps blood from the heart, to the lungs, and back, in order to oxygenate the blood. The systemic circuit carries (oxygenated) blood from the heart, to the rest of the body/organs, and back, in order to deliver the oxygen and nutrients to the body. It is therefore imperative that blood alternates between the two circuits. 4. List the four chambers of the heart and describe the major differences between the atria and ventricles. The four chambers of the heart are the right and left atrium, and the right and left ventricles. Both of the atria collect blood (RA from the pulmonary circuit, and LA from systemic circuit) Both of the ventricles pump blood out of the heart (RV pumps blood to pulmonary circuit, and LV pumps blood to systemic circuit). 5. Describe the structure and function of the pericardium. The pericardium consists of dense, fibrous tissue that surrounds and stabilizes the heart. It consists of a parietal layer and visceral layer that holds pericardial fluid. This fluid acts like a lubricant to reduce friction as the heart beats. 6. Compare and contrast the three layers of the heart wall. The epicardium is the outer layer of the heart. It consists of epithelium and connective tissue and is the visceral peridardium. The epicardium connects to the middle layer, the myocardium, which contains all of the cardiac muscle tissue organized into concentric layers. The myocardium allows the heart to “squeeze and twist” during contractions to force blood out of the heart. The myocardium is attached to the inner-most layer, the endocardium, which is composed of simple squamous epithelium. This layer lines the inside of the heart and makes up the heart valves. 7. Describe the pathway that a blood cell would follow through the heart beginning in the right atrium…and ending back in the right atrium. The pathway would go as follows: 1. Right atrium 2. Through the right AV valve (tricuspid) 3. Right ventricle 4. Through the pulmonary semilunar valve 5. Pulmonary trunk (left and right pulmonary arteries) 6. Capillaries in lungs 7. Left and right pulmonary veins 8. Left atrium 9. Through the left AV valve (bicuspid) 10. Left ventricle 11. Through the aortic semilunar valve 12. Aorta (ascending, aortic arch, descending) 13. Systemic circuit 14. Capillaries in body 15. Veins 16. Vena cava (superior and inferior) 17. Right atrium 8. Identify and explain ONE similarity and ONE difference between the left and right atria. Both atria collect blood and are similar in structure. The right atrium collects blood from systemic circuit (deoxygenated blood) The left atrium collects blood from the pulmonary circuit (oxygenated blood) 9. Identify and explain ONE similarity and ONE difference between the left and right ventricles. Both ventricles pump blood. The right ventricle pumps (deoxygenated) blood to the pulmonary circuit (pouch shaped, and thinner walls). The left ventricle pumps (oxygenated) blood to the systemic circuit (cylindrically shaped with thicker walls). 10. Compare and contrast the atrioventricular valves to the semilunar valves in the heart. In your explanation, be sure to include: a) location of valve(s); b) function of valve(s). The atrioventricular valves (AV) are located between the atria and ventricles. The right is a tricuspid, and the left is a bicuspid valve. They both are connected to chordae tendinae (heart strings) and papillary muscles. Their function is to prevent the back flow of blood into the atria from the ventricles when they contract. The semilunar valves are located in the pulmonary trunk and aorta. They are both tricuspids but are not connected to chordae tendinae. Their functions are to prevent the back flow of blood from the arteries back into the ventricles. 11. Damage to the semilunar valves on the right side of the heart would affect blood flow to which vessel? Why might this cause a problem? The semilunar valve on the right side prevents blood from re-entering the right ventricle from the pulmonary trunk. If this didn’t work correctly blood deoxygenated blood would not be able to reach the lungs. 12. What prevents the AV valves from swinging into the atria? The AV valves are connected to papillary muscles by chordae tendinae (heart strings) which prevent the valves from swinging into the atria. 13. What prevents the semilunar valves from allowing backflow? The shape of the semilunar valves prevent blood from flowing back into the heart. The semilunar valves have a concave shape which collects the blood flowing backwards, causing the valve to close. 14. Why is the left ventricle more muscular than the right ventricle? The right ventricle is only responsible for pumping blood to the lungs and back (short distance); the left ventricle must pump blood throughout the entire body which requires more pressure = thicker, more muscular walls. 15. What is the function of the coronary arteries? The coronary arteries carry oxygenated blood from the left ventricle to the actual tissue of the heart. They supply the cardiac tissue with oxygen and nutrients so that the heart can function properly. 16. Describe the difference between diastole and systole with regards to heart contractions. Systole refers to either atria or ventricles while they are contracting (which increases pressure and pumps blood out of chambers). Diastole refers to either atria or ventricles while they are relaxing (which decreases pressure and allows chambers to fill with blood). 17. Summarize the steps of the “cardiac cycle”: a. Step 1: Atrial systole begins: atrial contraction forces blood into the relaxed ventricles. b. Step 2: Atrial systole ends, atrial diastole begins c. Step 3: Ventricular systole—1st phase: ventricular contraction pushes the AV valves closed, but does not create enough pressure to open semilunar valves. nd d. Step 4: Ventricular systole—2 phase: As ventricular pressure rises and exceeds pressure in the arteries, the semilunar valves open and blood is pushed into the aorta and pulmonary trunk. e. Step 5: Ventricular diastole: As ventricles relax, pressure drops; blood flows back against cusps of semilunar valves and forces them closed. Blood flows into the relaxed atria. All chambers are relaxed before the new cardiac cycle begins. 18. Is the heart always pumping blood when pressure in the left ventricle is rising? Explain your answer. No. When pressure in the left ventricle first rises, the heart is contracting but no blood is leaving the heart. During the initial phase of contraction, both the AV and semilunar valves are closed. The increase in pressure results from increased tension as the cardiac muscle contracts. When ventricular pressure exceeds the pressure in the aorta, the aortic semilunar valves are forced open, and blood is rapidly ejected from the ventricle. 19. What events causes the “lubb-dupp” heart sounds as heard with a stethoscope? (HINT: There are 4 different heart functions that produce the sound) The “lubb” is produced by the simultaneous closing of the AV valves and the opening of the semilunar valves; the “dupp” is produced when the semilunar valves close. 20. If the cardioinhibitory center of the medulla oblongata were damaged, which part of the autonomic nervous system would be affected, and how would the heart be influenced? Explain your answer. Damage to the cardioinhibitory center of the medulla oblongata—a part of the parasympathetic division of the ANS—would result in fewer parasympathetic action potentials to the heart and an increase in heart rate due to sympathetic dominance. 21. If the cardioacceleratory center of the medulla oblongata were damaged, which part of the autonomic nervous system would be affected, and how would the heart be influenced? Explain your answer. Damage to the cardioacceleratory center of the medulla oblongata—a part of the sympathetic division of the ANS—would result in fewer sympathetic action potentials to the heart and a decrease in heart rate due to parasympathetic dominance. 22. Why is it a potential problem if the heart beats too rapidly? If the heart beats too rapidly, it has too little time to fill completely between beats. The heart pumps in proportion to the amount of blood that enters: The less blood that enters, the less the heart can pump. If it beats too fast, very little blood will enter the blood stream; tissues will suffer damage from the lack of blood supply. 23. Describe the three steps of ventricular contraction: a. Step 1: Rapid Depolarization: Caused by sodium ion entry. It lasts 3-5 msec, and ends with the closure of voltage-gated sodium channels. b. Step 2: The Plateau: Caused by calcium ion entry. It lasts ~175 msec, and ends with the closure of calcium channels. c. Step 3: Repolarization: Caused by potassium ion loss. It lasts 75 msec, and ends with the closure of potassium channels. 24. If the cells of the SA node were not functioning normally, how would the heart rate be affected? Explain your answer. If cells of the SA node were not functioning, cells of the AV node would become the pacemaker cells, so the heart would continue to beat but at a slower rate (40-60 beats/minute as compared to the SA node sending signals = 70-80 beats/minute) 25. Why is it important for the impulses from the atria to be delayed at the AV node before passing into the ventricles? Explain your answer. If impulses from the atria were not delayed at the AV node, they would be conducted through the ventricles so quickly by the bundle branches and Purkinje fibers that the ventricles would begin contracting immediately, before the atria had finished contracting. As a result, the ventricles would not be as full of blood as they could be, and the pumping of the heart would not be as efficient, especially during activity.