Download Remediation Pharmacology Unit Exam Name: Score:____/75 Which

Remediation Pharmacology Unit Exam
Name: _______________________ Score:____/75
1. Which of the following terms best describes a drug that stimulates a receptor for the
parsympathomimic system?
A. Anti-cholinergic
B. Adrenergic
C. Anti-adrenergic
D. Cholinergic
2. Which of the following enzyme when stimulated is thought to decrease Acetylcholine?
a. Adenlycyclase
b. Cholinesterase
c. Phosphodiesterase
d. Mast cells
3. Which of the following best describes the definition of an adrenergic?
A. A drug that blocks the receptor site for epinephrine
B. A drug that stimulates the receptor site for epinephrine
C. A drug that blocks the receptor site for acetylcholine
D. A drug that stimulates the receptor site for acetycholine
4. Alpha 1 receptor stimulation can have which of the following effects?
a. Mucous gland hypertrophy
b. Bronchial smooth muscle relaxation
c. Inhibition of histamine release
d. Vessel constriction
5. Which of the following drugs is considered a corticoid steroid?
A. Aformeterol
B. Foradil
C. Fluticosone
D. Cromolyn Sodium
6. Which of the following enzymes inactivates cAMP?
A. phosodiesterase
B. Choline
C. Cholinesterase
D. Acetyl CoA
7. Single isomer Beta 2 agonists include which of the following?
a. Serevent
b. Levalbuterol
c. Terbutaline
d. MicroNefrin
8. Which of the following is a use for Theophylline?
a. Increase respiratory muscle strength
b. Decrease ventilatory drive
c. Decreasing viscosity of mucus
d. Blockage of musanaric receptors
9. Which of the following drug blocks the response on the muscarinic (M3) receptor site in the
bronchial smooth muscle?
A. Levabluterol
B. Cholinesterase
C. Racemic Epi
D. Ipatropium Bromide
10. Foradil is a brand name for which of the following Beta Adrenergics?
a. Aformeterol
b. Terbutaline
c. Fluticasone
d. Formeterol
11. Which of the following is considered an expectorant?
a. Mucomyst
b. Sodium Bicarbonate
c. Dornase Alfa
d. Tilade
12. Which of the following drugs comes in an MDI formula that is breath activated?
a. Advair
b. Flovent
c. Xopenex
d. Maxair
13. Cholinergic stimulation causes all of the following EXCEPT:
A. Increase heart rate
B. Bronchoconstriction
C. Increased saliva production
D. Increased contractility of skeletal muscle
14. True or False: The autonomic nervous system is under voluntary control.
15. Which of the following is indicated for pseudomonas?
a.
b.
c.
d.
Nystatin
Amphotericin B
Isoconazole
Tobramycin
16. Which of the following is a common effect of adrenergic stimulation on airway smooth muscle?
A.
B.
C.
D.
Bronchodilation
Bronchoconstriction
Decreased mucus production
Increased inflammation
17. When stimulated, which of the following receptors cause bronchoconstriction?
a. M 3
b. Beta 1
c. M2
d. Alpha 1
18. Which antiinfective is commonly used for the treatment of RSV?
a. Ribavirin
b. Tobi
c. Intal
d. Pentamidine
19. Which of the following would be used in the presence of Croup?
a. Albuterol
b. Xopenex
c. Racemic Epinephrine
d. Fluticosone
20. Which of the following is an adverse side effect associated with Atrovent:
A. Tachycardia
B. Dry mouth
C. Hyperkalemia
D. Skeletal muscle paralysis
21. Which of the following describes the definition for a Trade (or brand) name?
a. The name assigned to a chemical by the USAN council when the chemical appears to
have therapeutic use and the manufacture wishes to market the drug.
b. Proprietary name given by a particular manufacturer.
c. The name indicating the drug’s chemical structure
d. The name that is used after the trade mark has expired
22. Which of the following are included in a prescription?
I. Patient’s name and address
II. Patient’s pharmacist name
III. Patient’s dianosis
IV. Transcription
A.
B.
C.
D.
I, and III
I and IV
II, III and IV
All of the above
23. Which of the following is considered hypertonic saline?
a. 0.9% NaCl
b. 9% NaCl
c. 0.45% NaCl
d. Sterile water
24. Which of the following is not considered an orphan drug?
A. Pulmozyme
B. Tobi
C. Prolastin
D. Albuterol
25. A drug with cholinergic effects would NOT result in which of the following?
a. Decreased heart rate
b. Salivation
c. Secretion of mucus
d. Increased heart rate
26. Which of the following definitions describe an antagonist?
A. A chemical or drug that binds to a receptor and creates an effect on the body
B. A chemical or drug that binds to a receptor but does not create an effect on the
body; it actually blocks the receptor site
C. An abnormal or unexpected reaction to a drug compared with the predicted effect
D. Pertains to the whole body, whereas the target for the drug is not local
27. Which of the following is a indication for Mucomyst?
a. Acute Bronchitis
b. Intrinsic asthma
c. Viral pneumonia
d. Acetaminophen overdose
28. Which of the following is considered a route of administration?
I. Enteral
II. Intrainjectable
III. Parenteral
IV. Inhalation
V. Transmembrane
A.
B.
C.
D.
I, II and V
II, III and IV
I, III and IV
III, IV and V
29. True or False: The pharmacodynamic phase is the time course and disposition of a drug in the
body, based on its absorption, distribution, metabolism and elimination.
30. Mechanisms for inducing bronchodilation include drugs that cause the following actions, except:
a. Promote the action of phosphodiesterase
b. Block the effects of parasympathetic system
c. Prevents the release of calcium and myosin
d. Stimulate the conversion of ATP to cAMP
31. Which of the following best describes pinocytosis?
A. A rapid decrease in response to a drug
B. Incorporation of a substance into a cell by a process of membrane engulfment and transport
C. Proportion of a drug that reaches the systemic system
D. A cell component that combines with a drug to change or enhance the function of a cell
32. Which organ is the primary site for drug metabolism?
A. The Lung
B. The Liver
C. The Kidney
D. The Tissues
33. Which of the following is the unit dose of Xopenex?
a. 1.25 mg
b. 2.5 mg
c. 0.63 mg
d. 0.31 mg
34. What effect does endogenous epinephrine have in the body during the fight or flight response?
A. Bronchoconstriction
B. Vessel dilation
C. Decreased heart rate
D. Bronchodilation
35. A common side effect with the use of Pulmozyme include::
a. Voice alteration
b. Osteoporosis
c. Thrush
d. Bronchoconstriction
36. Which of the following are advantages of aerosol drug delivery?
I. Aerosol doses are smaller than systemic doses
II. The number of variables affecting dose
III. Rapid onset of drug
IV. Dose estimation is difficult
A.
B.
C.
D.
I, II and IV
I and III
II and IV
All of the above
37. Which of the following aerosol particle size is ideal for upper airway deposition?
A. 5-10 microns
B. Greater than 10 microns
C. 0.8 -2 microns
D. 3-5 microns
38. What is the typical frequency for the delivery of Spiriva?
a. BID
b. QD
c. TID
d. PRN
39. Which of the following explains aerosol deposition by size and velocity?
A. Inertial impaction
B. Diffusion (Brownian motion)
C. Osmosis
D. Gravitational settling
40. What is the typical dose for Pulmozyme?
a. 0.5 mg
b. 2.5 mg
c. 1.25 mg
d. 0.63 mg
41. Advair is a combination of:
a. Albuterol and Foradil
b. Budesonide and formoterol
c. Serevent and Fluticosone
d. Budesonide and Salmeterol
42. Which of the following is NOT a common dose of Advair DPI?
a. 150/50
b. 250/50
c. 100/50
d. 500/50
43. Cells that are inhibited and are involved in airway inflammation do Not include:
a. Macrophages
b. Eosinophils
c. Mast Cells
d. Epithelial cells
44. Which of the following is a side effect seen with inhaled corticoid steroids?
a. Tachycardia
b. Hyperglycemia
c. Thrush
d. Osteoporosis
45. Which of the following steroid can be nebulized?
a. Fluticosone
b. Asmanex
c. Pulmicort
d. Aerospan
46. The use of Pulmozyme is indicated for:
a. Prophylactic maintenance with CF
b. Bronchiectasis
c. CF with infection
d. Bacterial pneumonia
47. Please list the mode of action of ALBUTEROL, include all steps for full credit:
48. Please list three side effects of systemic steroids:
49. A 56 year old with bilateral expiratory wheezes is admitted in the ER, the patient is short of
breath, SpO2 86% on room air, Please list an appropriate treatment action, include a medication
and dose:
Medication: ____________________________
Other treatment:________________________
50. A patient with severe persistent asthma arrives to the ER with bilateral wheezes. The patient is
awake/alert. Please list an appropriate treatment action, include a medication(s) and dose:
Medication: ____________________________
Other treatment:________________________