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Warm-Ups, Closures, and CTQs Week 21 Vocabulary Vestigial structures carbon dating natural selection adaptation genetic variation reproductive fitness wild-type gene duplications Monday, February 1st Warm-Up: A fossil was newly discovered with three intact DNA which was aligned using BLAST all translated genomes in the NCBI database. The results of the alignment is shown below. Sequence Similarity Sequence: 1 2 3 Snake 84% 82% 70% Parrot 95% 92% 90% Species Shark 71% 60% 72% Monkey 98% 74% 95% Fly 65% 45% 38% Construct a cladogram which most accurately places the evolutionary relationship to the other five species. CTQ #1: Radioactive carbon-14 dating conducted on rock samples at the fossil excavation site determined that the species became fossilized 165 million years ago. Furthermore, minor indentations in the fossil were analysed under a high-resolution computer topography scanner to very greatly resemble feathers. Re-create your cladogram considering this information as well as the table of data below showing the point of speciation for each of the five species. (LO 1.10) (LO 1.09) Species Snake Parrot Shark Monkey Fruit fly Point of Speciation from common human ancestor (million years ago) 200 150 400 10 495 CTQ #2: Which came first: the chicken, or the lizard egg? Design a plan using three scientific methods to determine modern lizards speciated from primitive birds or whether modern birds speciated from primitive lizards. Justify how the methods you used contribute to answering your driving question. (LO 1.11) Closure: Explain three scientific methods which provide evidence for biological evolution. (LO 1.12) Tuesday, February 2nd Warm-Up: Describe how primitive Fleenitians, a hairless, slimy population of minions, evolved into modern Fleenzaurs, which are furry mammals. (LO 1.25) CTQ #1: Explain two pieces of evidence scientists could analyze to determine that your description for Fleenzaurian evolution is correct. (LO 1.12) CTQ #2: The peppered moth is naturally preyed upon by the Magpie, a type of bird native to England. The Magpie contains a type photoreceptor neuron in its eye called a contra cell which detects differences in low contrast: for example, the difference between two dark-colored objects. The average number of contra cells per eye was determined over the course of 50 years following the start of the Industrial Revolution in England. The results of this experiment are listed in the table below. Year Avg. No. contra cells (x103) 1800 0.052 1810 0.072 1820 0.090 1830 0.113 1840 0.139 Explain the natural selection of high numbers of contra cells among Magpies following the start of the Industrial Revolution. (LO 1.2) Closure: Explain natural selection and provide an example of natural selection has resulted in evolution. Wednesday, February 3rd Warm-Up: Explain how a retrovirus can acquire genetic variation. CTQ’s #1&2: The Zika virus is a retrovirus which, historically, has been endemic to Brazil and has almost exclusively infected monkey populations (infection of human populations has been rare; see table below). In the past ten years, Brazil has experienced significant deforestation and expansion of its cities. State the point in time at which a mutation formed that causes easier infection in humans, and predict how the virus carrying this mutation had a selective advantage in a changing environment. (LO 1.26) (LO 4.16) (LO 1.5) Human, Monkey, and Zika Population Levels in a Deforested Region of Brazil, (1985–)* 1985- 1995- 2005- 2015- 2015- 2015- 2016Time Jan Jan Jan Jan May Aug Jan Human Population 3.6 4.0 4.6 5.4 5.4 5.5 5.5 (millions) Monkey 12.5 11.9 11.0 6.2 6.0 5.9 5.8 Population (thousands) Human Zika 0.003 0.004 0.002 0.005 0.150 12.0 20.0 Infections (thousands) *Note: Fleenor just made up these data. But he did see the 20,000 somewhere. Closure: Explain the importance of genetic variation in a changing environment. (LO 1.5) Thursday, February 4th Warm-Up: Describe an example of a mutation which is beneficial for the individual but deleterious for the individual’s offspring. CTQ #1: In a 2012 study published in the journal American Journal of Epidemiology, 171 newborn children not affected by malaria were tested every month for malaria. The proportion that continued to stay malaria-negative is plotted on the graph below over time. The solid line represents children heterozygous for the HBA allele, and the dashed line represents children homozygous for the wild-type allele. Assuming that all children affected by malaria died as a result, explain how the genetic makeup of this population changed over time. CTQ #2: The ligand Dll1 promotes formation of vertebrae in the spine: species with high levels of Dll1 activity during development, such as snakes, develop more vertebrae and longer spines. Predict the effects of a duplication of the Dll1 gene on a population of giraffids, an extinct deer-like animal which depended on fruit hanging from trees for survival. (LO 3.24) Closure: How did duplication of the SAS gene result in molecular variation of cellular function in eelpout fish? (LO 4.22) Friday, February 5th Warm-Up: Why do you predict the promoters of genes which have duplications evolve very rapidly? CTQ #1: It has been proposed (by Fleenor, five seconds ago) that fruit flies with red-pigmented eyes are better capable of finding food because they only absorb light at the blue end of the spectrum. Flies without red pigment have a mutation in the white gene (w--); thus, a reverted mutation back to wild-type (w+) would be a beneficial mutation in the population. Design an experiment that would determine whether a fly carrying red-eye mutation (w+) has a selective advantage in a white-eyed population over the course of five generations. State your independent variable, dependent variable, and hypothesis, and describe the experimental setup. CTQ #2: Male peacocks have large and extensive plumage (feathers) that often interfere with their ability to fly. However, the extensive plumage is correlated with greater ability to find a mate; thus, males with extensive plumage are sexier. Describe how males with extensive plumage have greater evolutionary fitness than males with short plumage. Closure: State three scientific methods used to create a cladogram. Learning Objectives This Week LO 1.9 evaluate evidence provided by data from many scientific discipline support biological evolution. (SP5.3) LO 1.10 refine evidence based on data from many scientific disciplines that support biological evolution. (SP5.2) LO 1.11 design a plan to answer scientific questions regarding how organisms have changed over time using information from morphology, biochemistry and geology. LO 1.12 connect scientific evidence from many scientific disciplines to support the modern concept of evolution. LO 1.13 construct and/or justify mathematical models, diagrams or simulations that represent processes of biological evolution. LO 1.25 describe a model that represents evolution within a population. LO 1.26 evaluate given data sets that illustrate evolution as an ongoing process. LO 1.2 evaluate evidence provided by data to qualitatively and/or quantitatively investigate the role of natural selection in evolution. LO 1.4 evaluate data-based evidence that describes evolutionary changes in the genetic makeup of a population over time. LO 1.5 connect evolutionary changes in a population over time to a change in the environment. LO 3.24 predict how a change in genotype, when expressed as a phenotype, provides a variation that can be subject to natural selection. LO 4.16 predict the effects of a change of matter or energy availability on communities. LO 4.22 construct explanations based on evidence of how variation in molecular units provides cells with a wider range of functions.