Download Ovarian cancer infographic_ Amended 4

Age
Early
diagnosis
Environmental
factors
Lifestyle
factors
Family
history
5-year survival
decreases
significantly
with stage of diagnosis2
92%
60%
28%
of ovarian cancers are diagnosed
at the advanced stage 2
The risk of
developing ovarian
cancer is increased in
women with specific
inherited genetic
abnormalities. One
of these risks is
associated with
BRCA mutations5
References:
1
2
3
4
5
6
73%
5-YEAR SURVIVAL
Ovarian cancer is the 7 most commonly
diagnosed cancer in women worldwide 6
th
Stage
I
BRCA1 and
BRCA2 belong to
a type of genes
known as tumour
suppressors
Up to 39%
of women
39%
Up to
of women who
inherit a BRCA1
mutation are likely
to develop ovarian
cancer 4
Up to
11-17%
of women
About 1.3%
of women
Up to
11 - 17%
of women who
inherit a BRCA2
mutation are likely to
develop ovarian
cancer 4
with a
in the general
with a
population BRCA2 mutation BRCA1 mut ation
will develop ovarian cancer
by age 70 years4
Cancer Research UK: Risk Factors for Ovarian Cancer. Available at: http://www.cancerresearchuk.org/cancer-info/cancerstats/types/ovary/riskfactors/ Last accessed: May 2016
SEER Cancer Factsheets: Ovary cancer. SEER 18 2003-2009. Available at: http://seer.cancer.gov/statfacts/html/ovary.html Last accessed: May 2016
Gadzicki D, et al. Genetic testing for familial/hereditary breast cancer—comparison of guidelines and recommendations from the UK, France, the Netherlands and Germany. J Community Genet. 2011;2:53-69.
National Cancer Institute. BRCA1 and BRCA2: Cancer Risk and Genetic Testing. http://www.cancer.gov/cancertopics/factsheet/Risk/BRCA Last accessed: May 2016
Cancer Genome Atlas Network. Integrated genomic analyses of ovarian carcinoma. Nature. 2011;474:609-15.
World Cancer Research Fund. Ovarian cancer statistics. Available from: http://www.wcrf.org/int/cancer-facts-figures/data-specific-cancers/ovarian-cancer-statistics Last accessed; May 2016
Stage
II/III
Stage
IV
OVARIAN CANCER AND
GENETIC TESTING
Genetic mutations can
play a role in the
development and
treatment of cancer
Individuals at risk of
carrying a genetic
mutation can be referred
for genetic testing3
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Several factors may
influence the development
and prognosis of ovarian
cancer, including : 1,2