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The Alimentary System (The digestive system) Alimentation • Is the combined processes of ingestion, digestion, absorption, assimilation, and egestion. • Process by which food substances are chemically changed into forms that can be absorbed and assimilated by the cells of the body. Ingestion-process by which food enters the digestive system. (eating) Digestion-The breakdown of large food molecules into a usable form. Absorption The process by which food molecules move into the blood stream to be carried to the cells of the body. Assimilation The incorporation of food molecules into the cells of the body to be used as energy, structural materials, or storage products. Egestion The expulsion of undigestable materials from the body. Digestive System is divided into 2 parts. 1. Alimentary Canal- Organs in which food passes through; oral cavity, pharynx, esophagus, stomach, small intestine, and colon. (large intestine) 30 ft. in length 2. Accessory Organs-glands or organs which secrete chemicals needed for the digestion of food substances; salivary glands, liver, gall bladder, pancreas. 4 layers of the Alimentary Gland 1. Mucosa- innermost, composed of simple columnar epith. • Functions in protection, absorption and secretion 2. Submucosa-composed of loose connective tissue and blood and lymphatic vessels and nerves. • Functions in the nourishment of the mucosa and surrounding tissues and carries away absorbed nutrients. 4 layers of alimentary canal 3. Muscularis 2 layers, inner layer is a circular layer of smooth muscle. Outer layer is a longitudinal layer. • Function is the movement and mixing of the contents of the tube. • Peristalsis- coordinated contraction of a tube. Serosa visceral peritoneum, composed of serous epithelium and connective tissue. • Functions is to secrete fluid to keep outer surfaces moist and lubricated. Organs of the Alimentary Canal Mouth (oral cavity) • Adapted to receive food and prepare it for digestion. • Lined with stratified squamous epithelium. • Tongue-muscular organ covered with taste receptors. • Functions in taste, speech, and swallowing. • Frenulum-attaches tongue to the floor of the mouth • Gingiva-gums Str. Squ. Epith. • Vestibule is the space between the cheek and gum Roof of Oral Cavity the Hard and Soft Palate Hard Palate is anterior. Palatine bone of the skull. Soft Palate is posterior extends to the uvula. Muscular, functions in swallowing. • Cleft Palate- malformation of the hard palate Teeth • Function in the mechanical digestion of foods. • Mastication is the chewing of food into smaller pieces so that enzymes can work at a faster rate. Teeth are composed of pulp, • • 1. 2. dentine, and enamel. The hardest substance in the human body. They are living tissue. 2 sets in your life time. Deciduous set (baby teeth) Permanent set (adult teeth) Deciduous Teeth- 20 3 types of teeth in the baby set: 1. Incisors- flat, chisel like teeth for cutting. 2. Canine- sharp pointed teeth for tearing and shredding. 3. Molars- flat teeth for crushing and grinding. Dental Formula I-8, C-4, M-4, M2-4. Permanent Set-32 • Have the same make-up as baby teeth. • New tooth added: • Bicuspid (premolar) - flat tooth for grinding. • Start to erupt by age 6 and usually thru by age 12. • 3rd Molar “Wisdom Tooth” erupts usually between 17 and 22. Dental Formula: I-8, C-4, B-4, B2-4, M-4, M2-4, M3-4 Dental Caries Tooth Decay • Bacteria living in the mouth produce acids which breaks down the enamel on teeth. • Gradually forming holes in the enamel. • These are called cavities. Salivary Glands • Secrete saliva, composed of water, mucous, amylase, and ions. • Functions: • in the digestion of carbohydrates (amylase) • lubrication of food • maintains the pH of the mouth • washes the teeth • neutralizes acids in mouth. 3 sets of Salivary glands 1. Parotid-located anterior and inferior to the ear. • Secretes a concentrated saliva with a great deal of amylase • Secretes thru Stenson’s duct opposite the 2nd Molar. Submandibular gland • About the size of a walnut. • Lies along the medial aspect of the mandibular body. • Secretes a watery dilute saliva thru Wharton’s duct that is located at base of the frenulum of the tongue. Sublingual gland Dilute saliva, located below the tongue inferior to the floor of the mouth. • Excretes thru 10-12 ducts along the vestibule of lower incisors Swallowing-Deglutition • The muscular act of swallowing. • Reflex controlled by vagus nerve. Events of deglutition 1. Food is chewed and mixed with saliva. (mastication) and rolled into a ball (bolus) and forced into the pharynx 2. The bolus upon reaching the pharynx triggers sensory receptors causing the muscular contraction that cause swallowing. 3. Food enters the esophagus and is carried by peristalsis to the stomach. Peristalsis • Wave like contraction of a tube. • Occurs in the alimentary canal as well as in arteries of the circ. system • Involves the coordinated contraction of both the longitudinal and circular planes of muscle. Esophagus • A straight muscular tube 10 in. length. • Serves as a passageway for food to reach the stomach. • Has a thick muscularis for forcing food down into stomach • Esophageal hiatus- a hole in the diaphragm where the esophagus enters the abdominal cavity. • Site of a hernia, hiatal hernia • Cardiac sphincter- circular muscle serves as the door to the stomach. • Heartburn is when acid from the stomach is splashed up into the esophagus causing a burning sensation in the chest. Stomach • J-shaped pouch • Located upper left quadrant of the abdominal cavity. • Functions: 1. Receive food and mix it with gastric juice. 2. initiate digestion of proteins 3. limited absorption 4. passes food to small intestine. • Stomach is distendible, it stretches, due to rugae, inner folds of the mucosa. Mucosa of the Stomach • Contains gastric pits composed of 3 cells: 1. Chief cell- secretes pepsin (enzyme) which breaks down proteins to polypeptides. 2. Parietal cell- secretes hydrochloric acid (HCl) kills germs and needed to maintain a low pH so pepsin can work. 3. Mucous cell- protects the mucosa so that pepsin will not break down the proteins in the stomach tissue. These products mixed together are known as gastric juice. Gastric Ulcers • also known as peptic ulcers • Due to stress, hypersecretion of HCl, or pepsin, or not enough mucous produced. • A bacteria, H. pylori. are also known to be a cause of peptic ulcers. • The mucosa is eaten away by the action of pepsin. Parts of the Stomach: Stomachs Small Intestine • Starts at the pyloric sphincter and extends some 18-20 ft. in length to the cecum of the colon. • It is the primary organ of digestion and absorption. • Functions: 1. Receives partially digested food material (chyme) from the stomach. 2. Receives secretions from the pancreas, liver and gall bladder. 3. digestion of carbs, proteins, and lipids by enzymes. 4. Absorption of carbs, proteins, and lipids into the blood stream. 5. Secretes and produces various enzymes 6. Transports the remaining undigestable material to the colon Small Intestine (cont) Divided into 3 segments: 1. duodenum- 25cm, primary organ of digestion. • The liver, gall bladder, and pancreas all secrete their products here thru the common bile duct and pancreatic duct 2. jejunum- approx. 15 ft in length, most absorption of nutrients occurs here. 3. Ileum- last 2 ft. very little absorbable materials left. • Ileocecal valve controls the passage of material into the large intestine (colon) Structure of the mucosa of the small intestine • The entire mucosa is covered with tiny microscopic finger-like projections called villi. • These increase the surface area of the small intestine some 600 times so that absorption can occur quickly. • Each villus is covered with even smaller microvilli which increase the surface area even more. • Intestinal glands secrete enzymes that break down; carbs, proteins, and lipids. • Brunner’s glands secrete mucous Mucosa of S.I. (cont) • The muscularis is the force which propels chyme thru the lumen of the small intestine • Within each villi are found, a lacteal, a lymphatic capillary, and a blood capillary. • The lacteal absorbs fats, the blood capillaries absorb other nutrients. Which are carried by the circulatory system to all the cells of the body. Enzyme Secretions of the S.I. Peptidase -proteins Sucrase-sucrose Maltase-maltose Lactase-lactose Nucleases-nucleic acids Lipase-lipids The Peritoneum- Mesenteric Membranes • These are membranes covering most of the organs of the abdominal cavity. • They support them loosely. • They also contain blood vessels, lymphatic vessels and nerves 1. Mesentary- supports small intestine 2. Greater omentum- supports stomach and small intestine 3. Lesser omentum- supports the stomach and liver Large Intestine (Colon) • 5-6 ft. in length, performs no digestive functions. • Functions: 1. Reabsorb water 2. Reabsorb electrolytes 3. Stores and forms feces for defecation. Parts of the Colon Cecum-blind pouch Veriform apppendix- lymphatic tissue Ascending colon Transverse colon Descending colon Sigmoid colon-holds and forms feces Rectum- feces stored here Anus- site of exit of feces Colon (cont.) • Large bacterial flora living in the large intestine. • This is a symbiotic relationship • They produce a number of B vitamins, and vitamin K. • These are absorbed by the large intestine and are used by our bodies. • Eschericia Coli is a predominant bacterial species living in our colons. • Methane is a byproduct of these bacteria, causes flatulation Defecation • Is controlled by 2 sphincter muscles. 1. Internal anal sphincterinvoluntary, must relax before defecation can occur. • Stimulated to relax by fullness in the rectum 2. External anal sphinctervoluntary, must relax and compression of the abdominal organs by the abdominal muscles must occur if defecation is to occur. Constipation- too little water Diarrhea- too much water Accessory Organs Of Alimentation The Liver • Largest gland in the body. • Located in the upper right quadrant of the abdominal cavity Functions: 1. 2. 3. Converts glucose to glycogen and stores it. Converts non-carbohydrates to glucose. Synthesizes cholesterol, phospholipids, and lipoproteins. 4. Synthesis of proteins, carb’s into fat. 5. Deamination of amino acids 6. Formation of urea 7. Stores Vitamins A, D, B12, and Iron 8. Destroys worn out rbc’s 9. Detoxifies the blood (portal vein) 10. Produces Bile. It actually has several more functions!!!!! Structure of the Liver • Liver is enclosed in a fibrous capsule and divided into lobes. • Lobes are further divided into lobules • Lobules are separated by vascular channels called hepatic sinusoids. • Blood from the digestive tract from the portal vein bring newly absorbed nutrients into the sinusoids and nourishes hepatic cells. • This immediately detoxifies the blood from the small intestine • Hepatic cells secrete a substance called bile. Bile Bile • A yellowish green liquid secreted and produced continuously by hepatic cells. • Composed of water, bile salts, bile pigments and cholesterol. • Bile pigments are produced by the destruction of rbc’s. • Bile is an emulsifier. Like soap or detergent. • Breaks down large fat globules into smaller fat globules. • Exposing a greater surface area for catalytic enzymes to break down fats. Gall Bladder • Pear shaped sac attached to the ventral surface of the liver. • Bile produced in the liver enters the gall bladder thru the cystic duct. • The cystic duct and hepatic duct of the liver merge to form the common bile duct. • The common bile duct carries bile from the gall bladder where its secreted to the duodenum. • The presence of fats in the duodenum stimulates the secretion of bile by the gall bladder. • Its controlled by the sphincter of Odi at the terminal end of the common bile duct. Gall Bladder (cont.) • The gall bladder stores and secretes bile only. The liver produces it. • When bile is stored in the gall bladder, water is continually being reabsorbed from the bile. • When water is reabsorbed, bile become more concentrated. • Sometimes when this occurs, too much cholesterol can crystallize forming gall stones. • Gall stones block the flow of bile from the gall bladder. • The removal of these stones is called a cholecystectomy, removal of the gall bladder. Pancreas • Located slightly below and behind the stomach. • Closely associated with the duodenum of the small intestine. • Pancreatic cells produce pancreatic juice which contains enzymes. • They are passed to the duodenum thru the pancreatic duct. • Which joins the common bile duct to enter the duodenum. • Pancreatic juice contains enzymes which break down proteins, carbs, and fats. Pancreatic enzymes: Pancreatic amylase-carbohydrates Pancreatic lipase-fats Trypsin-proteins Chymotrypsin-proteins Carboxypeptidase-proteins We’ve already discussed the endocrine function of the pancreas